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*  Organ specificity in autoimmune diseases: thyroid and islet autoimmunity in alopecia areata - Thyroid Disease ManagerThyroid...
Although alopecia areata (AA) is one of the most frequent organ-specific autoimmune diseases, the association of AA with other autoimmune diseases and the genetic basis of the association remain to be analyzed. Among the autoimmune diseases associated with AA, autoimmune thyroid disease was most frequent (10.0%), followed by vitiligo (2.7%) and rheumatoid arthritis (0.9%) but not type 1 diabetes (0.0%). The prevalence of thyroid-related autoantibodies in patients with AA was significantly higher than that in controls (TSH receptor antibody [TRAb]: 42.7% vs 1.2%, P = 1.6 × 10(-46); thyroid peroxidase antibody: 29.1% vs 11.6%; P = 1.7 × 10(-6)), whereas the prevalence of islet-related autontibodies was comparable between patients with AA and control subjects. The frequency of DRB1*15:01-DQB1*06:02, a protective haplotype for type 1 diabetes, was significantly higher in TRAb-positive (12.8%, P = .0028, corrected P value [Pc] = .02) but not TRAb-negative (7.1%, not significant) patients with AA ...
  http://www.thyroidmanager.org/2015/05/14/organ-specificity-in-autoimmune-diseases-thyroid-and-islet-autoimmunity-in-alopecia-areata/
*  NYU Cancer Institute Experts Present At The AACR 102nd Annual Meeting 2011 - Redorbit
Authors: Xue-Ru Wu, MD, professor, Urology and Pathology; Joseph B. Guttenplan, PhD, research associate professor, Environmental Medicine and Basic Science. Butyl-hydroxybutyl-N-nitrosamine (BBN) is a powerful carcinogen that specifically causes bladder cancer in rodents, the reason for such a high degree of organ specificity is unclear. BBN is a primary metabolite of the environmental carcinogen, dibutylnitrosamine and hence a potential human carcinogen. Mutagenesis induced by BBN in a chromosomally incorporated mutagenesis reporter gene was measured in bladder urothelial cells and smooth muscle cells of mice or rats and compared with mutagenesis in liver, kidney, ureter and forestomach. Since mutagenesis in the reporter gene is a surrogate for mutagenesis in general, researchers hypothesized mutations also induced in critical growth control genes would contribute to the tumor formation induced by BBN. Researchers found mutagenesis correlated with the organ ...
  http://www.redorbit.com/news/health/2025414/nyu_cancer_institute_experts_present_at_the_aacr_102nd_annual/
*  ORGAN SPECIFICITY AND LACTATE-DEHYDROGENASE ACTIVITY. DIFFERENTIAL INHIBITION BY UREA AND RELATED COMPOUNDS | Biochemical...
Thank you for your interest in spreading the word about Biochemical Journal.. NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.. ...
  http://www.biochemj.org/content/94/2/384
*  GENTAUR antibody-antibodies.com The Marketplace for Antibodies : Tissue-specific Differences in Immune Cell Subsets Located in...
antibody-antibodies.com is the marketplace for research antibodies. Find the right antibody for your research needs. Tissue-specific Differences in Immune Cell Subsets Located in the Naso-oropharyngeal-associated Lymphoid Tissues.
  http://www.antibody-antibodies.com/pubmed-29077981-Tissuespecific_differences_in_immune_cell_subsets_located_in_the_nasooropharyngealassociated_lymphoid_tissues.html
*  TCDB » Human MTPs
Lohi H, Kujala M, Makela S, Lehtonen E, Kestila M, Saarialho-Kere U,Markovich D, Kere J. Functional characterization of three novel tissue-specific anion exchangersSLC26A7, -A8, and -A9.J Biol Chem. 2002 Apr 19;277(16):14246-54. Epub 2002 Feb 07. PMID: 11834742 [PubMed - indexed for MEDLINE]. A second distinct family of anion exchangers, SLC26, in addition to the classical SLC4 (or anion exchanger) family, has recently been delineated. Particular interest in this gene family is stimulated by the fact that the SLC26A2, SLC26A3, and SLC26A4 genes have been recognized as the disease genes mutated in diastrophic dysplasia, congenital chloride diarrhea, and Pendred syndrome, respectively. We report the expansion of the SLC26 gene family by characterizing three novel tissue-specific members, named SLC26A7, SLC26A8, and SLC26A9, on chromosomes 8, 6, and 1, respectively. The SLC26A7-A9 proteins are structurally very similar at the amino acid level to the previous family members and show tissue-specific ...
  http://tcdb.org/hgnc_explore.php?symbol=SLC26A8
*  FHL2, a novel tissue-specific coactivator of the androgen receptor. | Sigma-Aldrich
Sigma-Aldrich offers abstracts and full-text articles by [J M Müller, U Isele, E Metzger, A Rempel, M Moser, A Pscherer, T Breyer, C Holubarsch, R Buettner, R Schüle].
  https://www.sigmaaldrich.com/catalog/papers/10654935
*  miRNA Tools and Services Market - Global Opportunity Analysis and Industry Forecast, 2014-2022 | CytoFluidix
miRNA is a set of small, non-coding RNA molecules that regulate gene expression post transcription. These molecules have an impact on a wide range of biological functions such as cell cycle control, stem cell differentiation, immune modulation, viral replication, and metabolic control. As the aforementioned processes are involved in the pathology of various diseases, tests performed on miRNAs help in disease treatment. Moreover, miRNAs can be easily manipulated than proteins, thus making them more useful for clinical diagnostics and therapeutics applications. The global miRNA tools and services market was valued at $146 million in 2015 and is expected to reach $620 million by 2022, growing at a CAGR of 23.4% during the forecast period. It is expected to witness significant growth owing to the rise in incidence of cancer, auto-immune, and cardiovascular diseases. In addition, miRNA molecules possess specific properties, such as higher tissue and organ specificity; and ability ...
  http://www.cytofluidix.com/mirna-tools-and-services-market-global-opportunity-analysis-and-industry-forecast-2014-2022/
*  JCI - The biology and function of exosomes in cancer
It has been assumed that exosomes are cellular trash bags for elimination of excess proteins, but many studies have shown that exosomes often exhibit certain specific markers, irrespective of the organ or cellular source. This suggests that certain proteins are transported to the exosomes with some degree of specificity. Additionally, distinct differences have been identified in the RNA and protein species present in exosomes, likely reflecting cellular and organ specificity. This second layer of complexity is dynamic and can change with the evolving status of the organ and cells within. Here, the pancreas is provided as an example, but this dynamism in exosomal contents presumably holds true for all organs. Therefore, exosome heterogeneity is a much more complex phenomenon than cellular heterogeneity and can be fleeting depending on stimuli and the functional status of the organ ...
  https://jci.org/articles/view/81135/figure/1
*  Attempts to Understand Metastasis Formation: v.1: Metastasis-Related Molecules - Ursula Gunthert; Walter Birchmeier; | Foyles...
In metastasis, tumor cells disseminate from the primary lesion and home to secondary organs where they may remain dormant for a long time. Metastasis formation is still the most feared manifestation for tumor patients and clinicians. Although improvements have been made concerning earlier detection and specific therapy, most of the cancer patients still die of distant metastases. The pu-rpose of these three volumes is to review the recent progress in molecular metas- tasis research and to attempt to further understand the biol- ogy of this multifocal process. With respect to present day molecular biology, the pioneers of metastasis research established the basic concepts of metasta- sis formation in the 1970s and 1980s, namely, clonal selection of metastatic cells, heterogeneity of metastatic subpopulations, organ specificity of metastasis and the importance of angio- genesis (Fidler, Kripke, Nicolson, Folkman and others). In the 1980s and 1990s, several of ...
  http://www.foyles.co.uk/witem/medical-veterinary/attempts-to-understand-metastasis,ursula-gunthert-walter-birchmeier-9783540606802
*  MicroRNA-222 and MicroRNA-146b are tissue and circulating biomarkers of recurrent papillary thyroid cancer - Lee - 2013 -...
Lee, J. C., Zhao, J. T., Clifton-Bligh, R. J., Gill, A., Gundara, J. S., Ip, J. C., Glover, A., Sywak, M. S., Delbridge, L. W., Robinson, B. G. and Sidhu, S. B. (2013), MicroRNA-222 and MicroRNA-146b are tissue and circulating biomarkers of recurrent papillary thyroid cancer. Cancer, 119: 4358-4365. doi: 10.1002/cncr.28254 ...
  http://onlinelibrary.wiley.com/doi/10.1002/cncr.28254/references?globalMessage=0
*  Vectors | Strader Laboratory
Understanding regulation of developmental events has increasingly required the use of tissue-specific expression of diverse factors affecting plant growth and environmental responses. To allow for cloning of presumptive promoters with tissue-specific activities, we created two plant expression vectors with multiple cloning sites upstream of a Gateway cassette for expression of either untagged or YFP-tagged genes of interest (Michniewicz et al., 2015) by modifying the pEarleyGate100 and pEarleyGate104 constructs (Earley et al., 2006). For fast and easy tissue-specific expression of desired genes, we further developed a set of Gateway-compatible tissue-specific gene expression vectors that allow for the expression of YFP-tagged or untagged proteins driven by various promoters (see table below). Additional vectors will be added to this table as they are created. These vectors provide an invaluable resource to the plant community, allowing for rapid generation of a variety of tissue-specific ...
  http://pages.wustl.edu/strader/vectors
*  Evaluation of Drugs with Specific Organ Toxicities in Organ Specific Cell Lines.
Safety attrition of drugs during preclinical development as well as in late stage clinical trials continues to be a challenge for the pharmaceutical industry for patient welfare and financial reasons. Hepatic-, cardiac- and nephro-toxicity remain the
  http://www.biomedsearch.com/nih/Evaluation-Drugs-with-Specific-Organ/22166485.html
*  Gentaur Molecular :US Biomax \ FDA normal human organ tissue array, 67cases 100 cores, replaced by FDA995 \ FDA993
Gentaur molecular products has all kinds of products like :search , US Biomax \ FDA normal human organ tissue array, 67cases_100 cores, replaced by FDA995 \ FDA993 for more molecular products just contact us
  http://www.antibody-antibodies.com/product_det.php?id=1004685&supplier=search&name=FDA%20normal%20human%20organ%20tissue%20array,%2067cases_100%20cores,%20replaced%20by%20FDA995
*  Gentaur Molecular :US Biomax \ Multiple organ cancer and 6 types of normal organ tissue array, including TNM and pathology...
Gentaur molecular products has all kinds of products like :search , US Biomax \ Multiple organ cancer and 6 types of normal organ tissue array, including TNM and pathology grade, 72 cases_72 cores, replaced by FDA808_2 \ FDA805-2 for more molecular products just contact us
  http://www.antibody-antibodies.com/product_det.php?id=1004763&supplier=search&name=Multiple%20organ%20cancer%20and%206%20types%20of%20normal%20organ%20tissue%20array,%20including%20TNM%20and%20pathology%20grade,%2072%20cases_72%20cores,%20replaced%20by%20FDA808_2
*  "Development in organ tissue culture of kidney rudiments from mutant mo" by waelsch S. Gluecksohn and T R. Rota
Gluecksohn, waelsch S. and Rota, T R., "Development in organ tissue culture of kidney rudiments from mutant mouse embryos." (1963). Subject Strain Bibliography 1963. 428 ...
  https://mouseion.jax.org/ssbb1963/428/
*  Tissue-specific expression of HSD11B2 and DNMTs in offs | Open-i
Tissue-specific expression of HSD11B2 and DNMTs in offspring exposed to prenatal stress.Average (mean ± SEM) mRNA levels of (A) HSD11B2, (B) DNMT1, and (C) DNM
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3383683_pone.0039791.g002&req=4
*  Nature's Laws on Health - Healing Naturally by Bee
Symptoms anywhere in the body, or in a specific organ, are "not" the dis-ease. Symptoms are "signs" the body lacks nutrition, is out of balance nutritionally and/or it has too many toxins that are poisoning it, or because of stress or injury. Therefore the "cause" must be treated, and not the symptom (sign) of dis-ease. In other words, the organs are not causing dis-ease, so they should not be treated. Organs only malfunction because of the "true causes" of dis-ease, and not because they suddenly stop functioning normally ...
  https://www.healingnaturallybybee.com/natures-laws-on-health
*  Stem Cells
Cell Biologics provides custom cell isolation service to our customers upon request. On request, we will isolate cells of any description from specific organs or tissues (any animal or human tissues) designated by our customers. If you would like to use of Custom Cell Isolation Service, for details regarding these special services, please contact us at service@cellbiologics.com.. Thank You!. ...
  http://cellbiologics.com/index.php?route=product/category&path=2_86
*  Macrophages
Cell Biologics provides custom cell isolation service upon request. On request, we will isolate cells of any description from specific organs or tissues (any animal or human tissues) designated by our customers. If you would like to use of Custom Cell Isolation Service, for details regarding these special services, please contact us at service@cellbiologics.com.. Thank You!. ...
  http://cellbiologics.com/index.php?route=product/category&path=2_383
*  Rabbit Cells
Cell Biologics provides custom cell isolation service to our customers upon request. On request, we will isolate cells of any description from specific organs or tissues (any animal or human tissues) designated by our customers. If you would like to use of Custom Cell Isolation Service, for details regarding these special services, please contact us at service@cellbiologics.com.. Thank You!. ...
  http://cellbiologics.com/index.php?route=product/category&path=2_54
*  Monkey Cells
Cell Biologics provides custom cell isolation service to our customers upon request. On request, we will isolate cells of any description from specific organs or tissues (any animal or human tissues) designated by our customers. If you would like to use of Custom Cell Isolation Service, for details regarding these special services, please contact us at service@cellbiologics.com.. Thank You!. ...
  http://cellbiologics.com/index.php?route=product/category&path=2_154
*  giving blood propecia Hair
41. While cost blтod have played a role in slowing the activation gviing programs (costs are in the range giving blood propecia 60,000 to 250,000, depending on the specific organ), these figures do not accurately reflect the cost of this procedure to society. 72, 276в282.
  http://shoping-plaza.ru/ed-online-pharmacy/giving-blood-propecia.html
*  Tissue-Specific Protein Extracts
Comprehensive collection of high-quality human total protein extracts ready for electrophoresis. Quickly confirms tissue-specific abundance of your protein. Easily accesses hard-to-obtain human tissues, including brain regions and fetal tissues.
  http://www.clontech.com/US/Products/Protein_Interactions_and_Profiling/Tissue-Specific_Protein_Extracts/Protein_Medleys?sitex=10020:22372:US&PROD=6jJm8cm4i_T6drONfZUmnDiZ:S&PROD_pses=ZG1C9A5E04D6C0CAAB5C8A6727B894F3A4948F7416B89FFC4BC941AD6CE416CF6D52C5E3B79851FE2A6D3B99A3D8B6D48C7120CC4725F4098F
*  Tissue-Specific Protein Extracts
Comprehensive collection of high-quality human total protein extracts ready for electrophoresis. Quickly confirms tissue-specific abundance of your protein. Easily accesses hard-to-obtain human tissues, including brain regions and fetal tissues.
  http://www.clontech.com/US/Products/Protein_Interactions_and_Profiling/Tissue-Specific_Protein_Extracts/Protein_Medleys?sitex=10020:22372:US&PROD=rpAs8tc4cp-TkZxuCGmkW1-C:S&PROD_pses=ZG1148204B5925B6797608F3978FB255DC5687973DDFB1013AA9721BDF36489D47BAB115F9973CA491013F4BFB9A0F7045AC5C962081ED8514
*  Ask About This Article
We all know that our body is made up of thousands of organs and all these organ combine together to form into various organ systems. All these organ s
  http://bmdkumar.articlealley.com/orthoaedician-helps-you-out-with-your-bone-2423208.html