Octamer transcription factors are a family of transcription factors which binds to the "ATTTGCAT" DNA sequence. Their DNA- ... Octamer+transcription+factors at the U.S. National Library of Medicine Medical Subject Headings (MeSH) (Articles with short ... "Characterization of chicken octamer-binding proteins demonstrates that POU domain-containing homeobox transcription factors ... "Octamer-binding transcription factors: genomics and functions". Frontiers in Bioscience (Landmark Edition). 18 (3): 1051-71. ...

Methods: We used electrophoretic mobility shift assays to examine the effect of the 3 SNPs on transcription factor binding in 3 ... mobility shift assays show that rs1046295 modulates allele-specific binding by the octamer-binding transcription factor 1 (Oct- ... Conclusion: These results suggest a mechanism by which rs1046295 may act as a regulatory variant modulating transcription at ... 1). Analysis of the relative expression levels of the 2 alleles of this SNP in heterozygous individuals showed a modest, but ...

PDB Compounds: (C:) octamer-binding transcription factor 1. SCOPe Domain Sequences for d1e3oc2:. Sequence; same for both SEQRES ... Protein Oct-1 [47415] (1 species). canonical 4-helical fold. *. Species Human (Homo sapiens) [TaxId:9606] [47416] (7 PDB ... Lineage for d1e3oc2 (1e3o C:1-75). *Root: SCOPe 2.08 *. Class a: All alpha proteins [46456] (290 folds). ... Fold a.35: lambda repressor-like DNA-binding domains [47412] (1 superfamily). core: 4 helices; folded leaf, closed. ...

In this respect, it is interesting to note that the ubiquitous transcription factor, octamer transcription factor-1, acts ... Octamer transcription factor-1 is another member of the homeodomain group of transcription factors. It acts as a positive ... Ishii Y, Hansen AJ, and Mackenzie PI (2000) Octamer transcription factor-1 enhances hepatic nuclear factor-1 alpha-mediated ... Studies on rodent UGT genes have demonstrated that the transcription factors hepatocyte nuclear factor 1 (HNF1) and CAAT- ...

Octamer-binding transcription factor 4 Oct-4 is a homeodomain transcription factor of the POU family.\ ... Octamer-binding transcription factor 4 Oct-4 is a homeodomain transcription factor of the POU family.\ ... Octamer-binding transcription factor 4. Oct-4 is a homeodomain transcription factor of the POU family.\ ... Inhibition of neural stem cell aging through the transient induction of reprogramming factors ...

Octamer-binding transcription factor 4 Oct-4 is a homeodomain transcription factor of the POU family.\ ... Octamer-binding transcription factor 4 Oct-4 is a homeodomain transcription factor of the POU family.\ ... Octamer-binding transcription factor 4. Oct-4 is a homeodomain transcription factor of the POU family.\ ... Inhibition of neural stem cell aging through the transient induction of reprogramming factors ...

Octamer Transcription Factor-2 * Proto-Oncogene Proteins / biosynthesis * Proto-Oncogene Proteins / genetics* ... Primary mediastinal B-cell lymphoma: high frequency of BCL-6 mutations and consistent expression of the transcription factors ... Stefano A Pileri 1 , Gianluca Gaidano, Pier Luigi Zinzani, Brunangelo Falini, Philippe Gaulard, Emanuele Zucca, Federica Pieri ... DOI: 10.1016/s0002-9440(10)63815-1 Abstract Although primary mediastinal (thymic) large B-cell lymphoma has been primarily ...

Octamer-binding transcription factor 4 (Oct4) has been shown to be an essential regulator of embryonic stem cell (ESC) ... is a transcription factor that is critically involved in the self-renewal of pluripotent stem cells, and its expression is ... from mouse somatic cells by transduction of four defined transcription factors. Here, we demonstrate the generation of iPS ... OAC1 increases transcription of the Oct4-Nanog-Sox2 triad and Tet1, a gene known to be involved in DNA demethylation. View ...

The octamer-binding transcription factor 4 (OCT4), an important regulator of embryonic pluripotency, enhanced CSC maintenance ... Several transcription factors involved in embryonic stem-cell maintenance such as the octamer-binding transcription factor 4 ( ... The octamer-binding transcription factor 4 (OCT4), an important regulator of embryonic pluripotency, enhanced CSC maintenance ... Among these factors, OCT4 has emerged as the master transcription factor governing self-renewal and pluripotency in stem cells ...

Octamer Transcription Factor-1. -. dc.subject. Protein-Tyrosine Kinases. -. dc.subject. Leukemia, Myelogenous, Chronic, BCR-ABL ... OCT-1-mediated influx is a key determinant of the intraceflular uptake of imatinib but not nilotinib, (AMN107): reduced OCT-1 ... The addition of prazosin, a potent inhibitor of OCT-1 cellular transporter, reduced the IUR and eliminated interpatient ... whereas OCT-1-mediated influx may be a key determinant of molecular response to imatinib, it is unlikely to impact on cellular ...

... octamer , and hepat ocyte nuclear factor-3 (HNF-3) family transcription factors. CC10 expression changes in relation to the ... Dilution: 1:100 using IHC-TekTM Antibody Diluent (Cat# IW-1000 or IW-1001) to reduce background and unspecific staining and ...

Description: A sandwich ELISA for quantitative measurement of Goat Octamer Binding Transcription Factor 4 in samples from blood ... Description: A sandwich ELISA for quantitative measurement of Goat Octamer Binding Transcription Factor 4 in samples from blood ... Description: A sandwich ELISA for quantitative measurement of Goat Octamer Binding Transcription Factor 4 in samples from blood ... Description: A competitive ELISA for quantitative measurement of Goat Octamer Binding Transcription Factor 1 in samples from ...

Octamer Transcription Factor-1 [1]. Octamer Transcription Factor-3 [1]. Odds Ratio [2]. ...

The transcription factor RBPJ forms a coactivator complex in the presence of a Notch signal, whereas it represses Notch target ... Importantly, RBPJL is not able to interact with Notch−1 to −4 and it does not support Notch-mediated transactivation. However, ... Both RBPJL and RBPJ bind to the same conserved octamer motif. Single-molecule experiments reveal that the binding times of both ... The ubiquitously expressed transcription factor RBPJ is the central switch that can actively repress transcription in the ...

After that, antibodies against octamer-binding transcription factor 4 (OCT4; R&D Systems, 1:300), T (R&D Systems, 1:100), GATA2 ... vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis. ... Fibroblast growth factor 2 modulates transforming growth factor beta signaling in mouse embryonic fibroblasts and human ESCs ( ... Developing a simple and efficient protocol for the differentiation of hPSCs into a specialized cell type is a key factor for ...

Human Octamer Binding Transcription Factor 4 (OCT4) ELISA Kit. SEA424Hu-10x96wellstestplate Cloud-Clone 10x96-wells test plate ... Human GABPa(GA Binding Protein Transcription Factor Alpha) ELISA Kit. Human GA Binding Protein Transcription Factor Alpha ( ... Human OCT4(Octamer Binding Transcription Factor 4) ELISA Kit. *Human OCTN1(Organic Cation/Ergothioneine Transporter) ELISA Kit ... Description: A sandwich ELISA kit for detection of Octamer Binding Transcription Factor 4 from Human in samples from blood, ...

... is a B cell-specific co-activator of the Oct1 and Oct2 transcription factors. It is involved in mediating the transcriptional ... The BOB.1 / OBF.1 / OCA-B protein (henceforth designated as BOB.1 / OBF.1) ... Surprisingly, animals deficient for BOB.1 / OBF.1 showed normal express … ... is a B cell-specific co-activator of the Oct1 and Oct2 transcription factors. It is involved in mediating the transcriptional ...

The Oct transcription factors recognise an octamer DNA element from which they regulate transcription of specific target genes ... as well as transcription factors in order to examine their function. The understanding of promoter complexity and transcription ... and as a consequence iNOS transcription does not proceed. Unravelling the mechanisms of transcription factor activity is ... This article is part of a Special Issue entitled: The Oct Transcription Factor Family, edited by Dr. Dean Tantin. ...

... octamer-binding transcription factor 3/4 (Oct 3/4), Sox2, Musashi1, nestin, nanog and pax2 (20,22). The expression of albumin ... In particular, the transfer of transcription factors, mRNAs and non-coding RNAs has been shown to induce epigenetic ... cDNA obtained by reverse transcription of 200 ng of RNA using the miScript Reverse Transcription kit was then subjected to RT- ... Following reverse transcription of the RNA (200 ng), the cDNA was subjected to RT-qPCR to quantify miRNAs as described above. ...

Octamer-Binding Transcription Factor 4, PBS: Phosphate Buffer Saline, PDGF-BB: Platelet-Derived Growth Factor BB, PDK1: ... The three key transcription factors POU5F1, NANOG, and SOX2 serve as differentiation repressors in the aforementioned signaling ... These pluripotent transcription factors are also known to contribute to somatic cell reprogramming into an ESC-like state, ... To study the stemness and enrichment of stem-like cells in both cell lines, we analyzed the pluripotent transcription factors ...

Li Y, Dong M, Kong F, Zhou J. Octamer transcription factor 1 mediates epithelial-mesenchymal transition in colorectal cancer. ... Xiao S, Liu L, Lu X, Long J, Zhou X, Fang M. The prognostic significance of bromodomain PHD-finger transcription factor in ... Social defeat stress promotes tumor growth and angiogenesis by upregulating vascular endothelial growth factor/extracellular ... 1. Relative expression of AFAP1-AS1 in a colorectal carcinoma (CRC) tissues (n = 15) and b colorectal carcinoma HCT116 and ...

The ubiquitous human octamer-binding transcription factor, Oct-1, is believed to regulate the expression of a number of ... The octamer motif may be required for the expression of both H2B and H2A genes. The degenerate octamer motif contained in this ... It is possible that histone gene transcription factors are stored for the same purpose. ... previously unidentified octamer-binding protein which has been termed Oct-R, for octamer-related. Oct-1 does not bind to a ...

... octamer-binding transcription factor 4) (Cat # wl01728, Wanleibio, Shenyang, China; Dilution rate: 1:2000), Ki67 (Cat # ab16667 ... Transcriptional factor six2 promotes the competitive endogenous RNA network between CYP4Z1 and pseudogene CYP4Z2P responsible ... 1. Tanshinone IIA attenuates breast cancer stemness in vitro. A, B qRT-PCR was utilized to examine the mRNA levels of stemness ... Additional file 1: Figure S1.. The effects of Tanshinone IIA on the cell cycle distribution of breast cancer cells and ...

Pituitary-specific positive transcription factor 1 (P28069) (SMART). OMIM:173110: Pituitary hormone deficiency, combined. ... the octamer-binding proteins Oct-1 and Oct-2, and the neural Unc-86 from Caenorhabditis elegans. POU domain genes have been ... TERNARY COMPLEX OF THE DNA BINDING DOMAINS OF THE OCT1 AND SOX2 TRANSCRIPTION FACTORS WITH A 19MER OLIGONUCLEOTIDE FROM THE ... POU proteins are eukaryotic transcription factors containing a bipartite DNA binding domain referred to as the POU domain. The ...

Octamer-binding transcription factor-4",. author = "Shuchun Lin and Wenfeng Mei and Haichun Lai and Xiufeng Li and Huanjiao ... which are rich in octamer-binding transcription factor (OCT)-4, inhibitor of differentiation 1 (ID1), nuclear factor (NF)-κB, ... which are rich in octamer-binding transcription factor (OCT)-4, inhibitor of differentiation 1 (ID1), nuclear factor (NF)-κB, ... which are rich in octamer-binding transcription factor (OCT)-4, inhibitor of differentiation 1 (ID1), nuclear factor (NF)-κB, ...

The expression of stemness transcription factors, including Nanog homeobox (NANOG), octamer-binding transcription factor 4 (OCT ... as well as the mRNA expression level of stemness transcription factors. Consistent with the in vivo results, HIF-1α and Akt/GSK ... cancer stemness in vitro was detected using suspension sphere experiments and the expression of stemness transcription factors ... v-Myc avian myelocytomatosis viral oncogene homolog (C-MYC) and hypoxia-inducible factor-1α (HIF-1α), was detected using real- ...

... the identification of cis-regulatory sites in previously unexplored regions of the genome and the cooperating transcription ... Selective binding of steroid hormone receptors to octamer transcription factors determines transcriptional synergism at the ... Figure 4: Identification of enriched motifs within the estrogen receptor binding sites and validation of transcription factor ... Figure 5: Involvement of cooperating transcription factors at estrogen receptor binding sites.. ...

Okamoto K, Okazawa H, Okuda A, Sakai M, Muramatsu M, Hamada H. A novel octamer binding transcription factor is differentially ... The entire BD Mouse Pluripotent Stem Cell Transcription Factor Analysis Kit must be stored in the dark at 2° to 8°C. Do not ... mouse ESC from the ES-E14TG2a cell line stained using the BD Stemflow Mouse Pluripotent Stem Cell Transcription Factor Analysis ... mouse ESC from the ES-E14TG2a cell line stained using the BD Stemflow Mouse Pluripotent Stem Cell Transcription Factor Analysis ...

... responsible for reduced KIAA0319 expression resides on the risk haplotype close to the genes transcription start site. We ... The causative variant(s) remains unknown but may modulate gene expression, given that (1) a dyslexia-associated haplotype has ... Knocking down OCT-1 expression in the neuronal cell line SHSY5Y using an siRNA restores KIAA0319 expression from the risk ... the strongest association has been found for the region spanning exon 1 of KIAA0319. Here, we test the hypothesis that variant( ...

Transcription of the gene encoding octamer-binding transcription factor 4 was higher in blastocysts obtained from in vivo ... Semiquantitative reverse-transcription polymerase chain reaction assay was used to compare the gene expression of, the cell ... MRS Advances / Volume 1 / Issue 15 / 2016 Published online by Cambridge University Press: 11 January 2016, pp. 1021-1027 Print ... We found that alcohol intake increased the risk of CRC; OR (95 % CI) was 2·02 (1·41, 2·87) for ≥60 g/d drinkers compared with ...