Occludin also plays an important role in the apoptosis. The C-terminus of occludin is important in receiving and transmitting ... Occludin plays a critical role in maintaining the barrier properties of a tight junction. Thus, mutation or absence of occludin ... Disruption of occludin regulation is an important aspect of a number of diseases. Strategies to prevent and/or reverse occludin ... "Entrez Gene: OCLN occludin". "OCLN occludin [Homo sapiens (human)] - Gene - NCBI". Chen Y, Merzdorf C, Paul DL, Goodenough DA ( ...

Occludin antibody - 447 005. Occludin is an integral membrane protein located at the tight junction ... Occludin, a 65-kDa tetraspan integral membrane protein, plays a role in the formation and regulation of the tight junction ... Occludin is localized at tight junctions of both epithelial and endothelial cells. (1) It is highly expressed in the testis, ... Expression of occludin is required for the infection of liver cells by the hepatitis C virus (HCV). (2) ...

Hirase T, Staddon JM, Saitou M, et al: Occludin as a possible determinant of tight junction permeability in endothelial cells. ... Bamforth SD, Kniesel U, Wolburg H, Engelhardt B and Risau W: A dominant mutant of occludin disrupts tight junction structure ... Feldman GJ, Mullin JM and Ryan MP: Occludin: structure, function and regulation. Adv Drug Deliv Rev. 57:883-917. 2005. View ... The present study also demonstrated that netrin‑1 significantly increased the downregulation of claudin‑5, occludin and ZO‑1 ...

... especially occludin correlate with blood-brain barrier (BBB) disruption caused by central nervous system (CNS) inflammation ... Studies also have revealed that VEGF was involved in occludin expression [ 29]. The study revealed that the level of occludin ... VEGF/ p-VEGFR-2 signaling pathway was involved in the effects of propofol and TNF-α on the ERK and occludin in hCMEC/D3 cells. ... It has also been reported that p38MAPK was also activated by TNF-α and was involved in occludin expression [ 13]. As shown in ...

Occludin, the putative tight junction integral membrane protein, is an attractive candidate for a protein that forms the actual ... We also do not know how occludin forms the cell-cell contact at the tight junction. Does it bind to another occludin from the ... Immunofluorescence analysis of occludin showed that the recovery of TER correlated with the reappearance of occludin at the ... Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions ...

ELISA Kit for Occludin (OCLN). ABCC29505 * $70000 $700.00 Unit price/ per ...

This Human Occludin ELISA kit is used to quantitatively determine human OCLN in serum, plasma, tissue homogenates, cell lysates ... HuR promotes occludin translation by blocking occludin mRNA translocation to P-bodies via the displacement of CUGBP1. PMID: ... Occludin protein may contribute to the development of cervical cancer. However, it was not correlated with the clinical ... Low occludin expression is associated with Renal cell carcinoma. PMID: 28534944. *decreased interaction between ZO-1 and ...

Description: A sandwich ELISA kit for detection of Occludin from Rat in samples from blood, serum, plasma, cell culture fluid ... Description: A sandwich ELISA kit for detection of Occludin from Human in samples from blood, serum, plasma, cell culture fluid ... Description: A sandwich ELISA kit for detection of Occludin from Mouse in samples from blood, serum, plasma, cell culture fluid ... Description: A sandwich ELISA kit for quantitative measurement of Human OCLN (Occludin) in samples from Serum, Plasma, Cell ...

Occludin. Damit wurde ein gemeinsamer molekularer Mechanismus für die Assoziation von ZO-1 an adherens und tight junction ... Unsere Ergebnisse bestätigen das Konzept, dass ZO-1 nacheinander mit a-Catenin an den adherens junction und Occludin an den ... Untersuchungen zum Bindungsmechanismus von Occludin und α-Catenin an ZO-1. Title: Untersuchungen zum Bindungsmechanismus von ... Strong spatial evidence indicates that the occludin C-terminal coiled-coil domain dimerizes and interacts as a four-helix ...

The hallmark of acalculous cholecystopathy, frequently called biliary dyskinesia, is recurrent right upper quadrant pain in the absence of gallstones. Acalculous cholecystitis refers to cholecystitis without gallstones.

We now report that TJ function, as well as claudin-1 and occludin expression, change in parallel during late epidermal ... with concurrent upregulation of claudin-1 and occludin. TJ then become more permeable to ions and water as the fetus approaches ...

We also found that Ang-1 inhibits thrombin induced tyrosine phosphorylation of Occludin and promote Occludin interaction with ... We also found that Ang-1 inhibits thrombin induced tyrosine phosphorylation of Occludin and promote Occludin interaction with ... We also found that Ang-1 inhibits thrombin induced tyrosine phosphorylation of Occludin and promote Occludin interaction with ... We also found that Ang-1 inhibits thrombin induced tyrosine phosphorylation of Occludin and promote Occludin interaction with ...

Dive into the research topics of Cyclic strain-mediated regulation of vascular endothelial occludin and ZO-1: influence on ... Cyclic strain-mediated regulation of vascular endothelial occludin and ZO-1: influence on intercellular tight junction assembly ... Cyclic strain-mediated regulation of vascular endothelial occludin and ZO-1: influence on intercellular tight junction assembly ... These changes were accompanied by reduced occludin tyrosine phosphorylation (75.7+/-8%) and increased ZO-1 serine/threonine ...

... and phosphatase assay were performed to study the effect of DUSP3 on the TJ protein occludin (OCLN). Mutations of Tyr residues ... Rao R. Occludin phosphorylation in regulation of epithelial tight junctions. Ann NY Acad Sci. 2009;1165:62-8. ... Occludin proteolysis and increased permeability in endothelial cells through tyrosine phosphatase inhibition. J Cell Sci. 1999; ... The tight junction-specific protein occludin is a functional target of the E3 ubiquitin-protein ligase Itch. J Biol Chem. 2002; ...

keywords = "Ameloblast, Claudin, Occludin, Tight junction, Tooth",. author = "Masaki Hata and Tadafumi Kawamoto and Mariko ... Hata M, Kawamoto T, Kawai M, Yamamoto T. Differential expression patterns of the tight junction-associated proteins occludin ... Dive into the research topics of Differential expression patterns of the tight junction-associated proteins occludin and ... T1 - Differential expression patterns of the tight junction-associated proteins occludin and claudins in secretory and mature ...

... occludin; Cldn2, claudin 2; FcRn, neonatal constant fragment receptor; Blimp-1, B-lymphocyte-induced maturation-protein-1; REF ...

Sections were incubated with rabbit anti-occludin or rabbit anti-ZO-1 (1:400 for ZO-1 and 1:100 for occludin staining; Zymed ... Cryosections (5 μm) were fixed in acetone at −20°C for 5 min for occludin and fixed in ethanol for 30 min at room temperature ... Immunofluorescence analysis of occludin and ZO-1. Jejunum segments were immediately removed, washed with PBS, mounted in ... Representative immunofluorescence staining for (A) ZO-1 and (B) occludin in ob/ob mice fed a normal diet (Ob-CT), non-prebiotic ...

Sections were incubated with rabbit anti-occludin or rabbit anti-ZO-1 (1:400 for ZO-1 and 1:100 for occludin staining; Zymed ... Cryosections (5 μm) were fixed in acetone at −20°C for 5 min for occludin and fixed in ethanol for 30 min at room temperature ... Immunofluorescence analysis of occludin and ZO-1. Jejunum segments were immediately removed, washed with PBS, mounted in ... Representative immunofluorescence staining for (A) ZO-1 and (B) occludin in ob/ob mice fed a normal diet (Ob-CT), non-prebiotic ...

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Van Itallie CM, Lidman KF, Tietgens AJ, Anderson JM (2019) Newly synthesized claudins but not occludin are added to the basal ... They consist of claudins and occludin. Claudins form an independent protein family. According to their sequence homology, they ...

We further observed subapical localization of occludin in a nodal pattern, indicative of functional tight junctions (Fig. 2d, ... Ca1004, 1:100), mouse monoclonal anti-occludin (Invitrogen, Cat. No. 33-1500, 1:100) and rabbit polyclonal anti-vimentin (Cell ... Epithelial cells form tight junctions visible by labelling for occludin (green, left). Organoids also contain occasional ...

Occludin: a novel integral membrane protein localizing at tight junctions. J. Cell Biol. 123, 1777-1788 (1993). ...

Binge alcohol exposure significantly reduced the levels of AJ proteins (e.g., ZO-1, claudin-1, and occludin in Figure 3B) and ... and occludin in ethanol-exposed mice (Figure 3D). Consistently, TUNEL analyses revealed that alcohol exposure elevated the ... occludin (1:1000 dilution; Santa Cruz Biotechnology), claudin-1 (1:1000 dilution; Abcam), or glyceraldehyde 3-phosphate ...

occludin. increases cleavage. ISO. actinidine results in increased cleavage of OCLN protein. CTD. PMID:25042511. NCBI chr 2: ...

The reaction was very strong with M2 (OD 2.58) and with NFP (OD 2.00). The only moderate reaction was with occludin+zonulin (OD ... Different peptides of occludin, zonulin, claudin 5 and 6, beta-catenin, aquaporin-4 (AQP4), presenilin, fibulin, protein ... Our study found immune reactivity between SARS-CoV-2 antibodies and barrier target proteins; occludin+zonulin, beta-catenin, ... occludin+zonulin (OD 0.61), ENA (OD 0.53) MBP (OD 0.41), phospholipid (OD 0.37) and alpha-myosin (OD 0.36) is considered low. ...

Cited in 4 publications. View Rabbit Polyclonal anti-Tight Junction Protein 2 Antibody (NBP1-86850). Validated Applications: WB, ICC/IF, IHC, IP. Validated Species: Human, Mouse, Rat. Validated by: Orthogonal Strategies. Sample size available.

Anti-Occludin antibody [EPR20992] (ab216327) Knockout Human CAT (Catalase) knockout HeLa cell line (ab265250) ...

ab276131), occludin (cat. no. ab216327), claudin 1 (cat. no. ab211737), BCL6 (cat. no. ab33901), phosphorylated (p)-p38 (cat. ... 3A, western blotting revealed that IL-13 significantly reduced the levels of ZO-1, occludin and claudin 1 in JME/CF15 cells ... 5E-G). Additionally, siRNA-BCL6 significantly inhibited the production of ZO-1, occludin and claudin 1 in IL-13-induced cells ... A) Protein levels of ZO-1, occludin and claudin 1 in JME/CF15 cells were measured by western blotting. (B) Immunofluorescence ...

Loss of occludin affects tricellular localization of tricellulin. Mol Biol Cell 2008; 19: 4687-4693. ... ZO-1, occludin and claudins are the main junction proteins determining paracellular permeability [21, 22]. Claudins are ... claudins and occludins, which are linked to cytoskeletal proteins and each other by scaffolding proteins, such as zonula ... Overexpression of occludin increases epithelial permeability to small hydrophilic molecules while reducing ion movement [26]. ...

As shown by immunohistochemistry, occludin localizes to the oocyte-facing granulosa cell surface. Occludin and thus tight ... Activin A and Follicle-Stimulating Hormone Control Tight Junctions in Avian Granulosa Cells by Regulating Occludin Expression ... Small white follicles, which have not yet started yellow yolk incorporation, show pronounced occludin expression in vitro and ... By contrast, yellow yolk-incorporating small yellow follicles exhibit much lower levels of occludin, and hierarchical, ...