Nitroreductase - Wikipedia
Members of this family include oxygen-insensitive NAD(P)H nitroreductase (flavin mononucleotide-dependent nitroreductase) (6,7- ... Nitroreductases are a family of evolutionarily related proteins involved in the reduction of nitrogen-containing compounds, ... An example of a potential cold-active enzyme for prodrug therapy was described using a cold-active nitroreductase, Ssap-NtrB ( ... Bryant, C.; DeLuca, M. (1991-03-05). "Purification and characterization of an oxygen-insensitive NAD(P)H nitroreductase from ...
RCSB PDB - 3G14: Crystal structure of nitroreductase family protein (YP 877874.1) from Clostridium novyi NT at 1.75 A resolution
Crystal structure of nitroreductase family protein (YP_877874.1) from Clostridium novyi NT at 1.75 A resolution ... Nitroreductase family protein. A, B. 193. Clostridium novyi NT. Mutation(s): 0 Gene Names: noxC, NT01CX_1801, YP_877874.1. EC: ... Crystal structure of nitroreductase family protein (YP_877874.1) from Clostridium novyi NT at 1.75 A resolution. *PDB DOI: ... Crystal structure of nitroreductase family protein (YP_877874.1) from Clostridium novyi NT at 1.75 A resolution. Joint Center ...
RCSB PDB - 3KWK: Crystal structure of Putative NADH dehydrogenase/NAD(P)H nitroreductase (NP 809094.1) from BACTEROIDES...
H nitroreductase (NP_809094.1) from BACTEROIDES THETAIOTAOMICRON VPI-5482 at 1.54 A resolution ... Putative NADH dehydrogenase/NAD(P)H nitroreductase. A. 175. Bacteroides thetaiotaomicron VPI-5482. Mutation(s): 0 Gene Names: ... Crystal structure of Putative NADH dehydrogenase/NAD(P)H nitroreductase (NP_809094.1) from BACTEROIDES THETAIOTAOMICRON VPI- ... Crystal structure of Putative NADH dehydrogenase/NAD(P)H nitroreductase (NP_809094.1) from BACTEROIDES THETAIOTAOMICRON VPI- ...
PRIME PubMed | Targeted disruption of the gene encoding the classical nitroreductase enzyme in Salmonella typhimurium Ames test...
Targeted disruption of the gene encoding the classical nitroreductase enzyme in Salmonella typhimurium Ames test strains TA1535 ... This reduction almost completely eliminated the nitroreductase activity of strain TA1538. In contrast, the nitroreductase ... This reduction almost completely eliminated the nitroreductase activity of strain TA1538. In contrast, the nitroreductase ... Role of classical nitroreductase and O-acetyltransferase on the mutagenicity of nifurtimox and eight derivatives in Salmonella ...
Nitroreductase-Activatable Morpholino Oligonucleotides
for in Vivo Gene Silencing
"Nitroreductase-Activatable Morpholino Oligonucleotides for in Vivo Gene Silencing" vol. 9, no. 9, 2014. Export RIS Citation ... 2014). Nitroreductase-Activatable Morpholino Oligonucleotides for in Vivo Gene Silencing. 9(9). Yamazoe, Sayumi and McQuade, ... Title : Nitroreductase-Activatable Morpholino Oligonucleotides for in Vivo Gene Silencing Personal Author(s) : Yamazoe, Sayumi; ... We describe here a new class of caged morpholino oligonucleotides that can be activated by the bacterial nitroreductase NfsB. ...
"Urea-facilitated uptake and nitroreductase-mediated transformation of " by Padmini Das, Dibyendu Sarkar et al.
Enhanced activity of nitroreductase enzyme (NR) in TNT treated vetiver plants was observed, which coincides with the prevalence ... Enhanced activity of nitroreductase enzyme (NR) in TNT treated vetiver plants was observed, which coincides with the prevalence ... Das, P., Sarkar, D., Makris, K., & Datta, R. (2015). Urea-facilitated uptake and nitroreductase-mediated transformation of 2,4, ... Urea-facilitated uptake and nitroreductase-mediated transformation of 2,4,6-trinitrotoluene in soil using vetiver grass. ...
Discovery and Optimisation of Bacterial Nitroreductases for Use in Anti-Cancer Gene Therapy
NitroreductaseGDEPTDirected evolutionSchool: School of Biological Sciences069999 Biological Sciences not elsewhere classified ... Discovery and Optimisation of Bacterial Nitroreductases for Use in Anti-Cancer Gene Therapy. ... candidates for anti-cancer therapy by virtue of their ability to be converted to potent DNA alkylating agents by nitroreductase ...
The implication of Mycobacterium tuberculosis-mediated metabolism of targeted xenobiotics | Nature Reviews Chemistry
Identification of a mycothiol-dependent nitroreductase from Mycobacterium tuberculosis. ACS Infect. Dis. 4, 771-787 (2018). ... 2b). Two nitroimidazole drugs delamanid and pretomanid (36) are also bioactivated by Mtb nitroreductases (Fig. 2b). In the ... In addition to its function as a nitroreductase, Mrx-2 conferred partial protection to menadione stress. However, 44 showed low ... AmiC, putative amidase; Ddn, deazaflavin-dependent nitroreductase; DHFR, dihydrofolate reductase; FbiC, Fgd1, probable F420 ...
Molecules | February 2018 - Browse Articles
Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing. |...
Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing.. ... Nitroreductase enzymes are responsible for the reduction of nitro functional groups to amino functional groups, and are found ... Transgenic zebrafish models have been developed for tissue-specific cell ablation, which use nitroreductase to ablate specific ... Investigating the application of a nitroreductase-expressing transgenic zebrafish line for high-throughput toxicity testing.. ...
Characterization of a Pseudomonad 2-Nitrobenzoate Nitroreductase and its Catabolic Pathway-Associated 2-Hydroxylaminobenzoate...
Characterization of a Pseudomonad 2-Nitrobenzoate Nitroreductase and its Catabolic Pathway-Associated 2-Hydroxylaminobenzoate ... Characterization of a Pseudomonad 2-Nitrobenzoate Nitroreductase and its Catabolic Pathway-Associated 2-Hydroxylaminobenzoate ... Characterization of a Pseudomonad 2-Nitrobenzoate Nitroreductase and its Catabolic Pathway-Associated 2-Hydroxylaminobenzoate ... to the sequential formation of 2-hydroxy/aminobenzoate and 3-HAA are catalyzed by a NADPH-dependent 2-NBA nitroreductase (NbaA ...
MSMEG 2921 MSMEG 2921 NADPH-flavin oxidoreductase (EC 1.6.99.-) (Nitroreductase) (EC 1.6.99.3)Mycobacterium smegmatis (strain...
PDB 7T2Z | Chain THE STRUCTURE OF HAEMOPHILUS INFLUENZAE RD KW20 NITROREDUCTASE COMPLEXED WITH 1-METHYL-5-NITROIMIDAZOLE | 7T2Z...
THE STRUCTURE OF HAEMOPHILUS INFLUENZAE RD KW20 NITROREDUCTASE COMPLEXED WITH 1-METHYL-5-NITROIMIDAZOLE - 7T2Z , canSARS ... THE STRUCTURE OF HAEMOPHILUS INFLUENZAE RD KW20 NITROREDUCTASE COMPLEXED WITH 1-METHYL-5-NITROIMIDAZOLE ... THE STRUCTURE OF HAEMOPHILUS INFLUENZAE RD KW20 NITROREDUCTASE COMPLEXED WITH 1-METHYL-5-NITROIMIDAZOLE ...
Iyd MGI Mouse Gene Detail - MGI:1917587 - iodotyrosine deiodinase
British Library EThOS: Nitroaromatic pro-drug activation and resistance in the African trypanosome
SCOPe 2.08: Domain d1vkwa1: 1vkw A:1-206
Superfamily d.90.1: FMN-dependent nitroreductase-like [55469] (3 families) *. Family d.90.1.2: Putative nitroreductase TM1586 [ ... Fold d.90: FMN-dependent nitroreductase-like [55468] (1 superfamily). core: (alpha-beta-alpha-beta)2; 3 layers a/b/a; ... PDB Compounds: (A:) putative nitroreductase. SCOPe Domain Sequences for d1vkwa1:. Sequence; same for both SEQRES and ATOM ... Protein Putative nitroreductase TM1586 [111079] (1 species). *. Species Thermotoga maritima [TaxId:2336] [111080] (1 PDB entry) ...
Environmental Fate and Transport of a New Energetic Material, CL-20
Hu L - Search Results - PubMed
WikiGenes - SureCN60839 - N-(3-methyl-1,1-dioxo-1,4-thiazinan-4-yl)...
Role of classical nitroreductase and O-acetyltransferase on the mutagenicity of nifurtimox and eight derivatives in Salmonella ... Evidence of an outer membrane-located nitroreductase. Moreno, S.N., Mason, R.P., Docampo, R. J. Biol. Chem. (1984) [Pubmed] ... Evidence of an outer membrane-located nitroreductase [7].. *Nifurtimox is reduced by rat liver microsomes to a nitro anion-free ... Role of classical nitroreductase and O-acetyltransferase on the mutagenicity of nifurtimox and eight derivatives in Salmonella ...
Dibs Sarkar | Stevens Institute of Technology
Xenopus: A Laboratory Manual