1994a) Properties of neuroprotective cell-permeant Ca2+ chelators: effects on [Ca2+]i and glutamate neurotoxicity in vitro. J ... 1977) Use of a water soluble carbodiimide as a fixing agent. Acta Histochem Cytochem 10:14-37. ... 1994) Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino ... Unlike neuroprotective mechanisms, the physiological effects of exogenous Ca2+ buffers have been better characterized. ...http://www.jneurosci.org/content/17/10/3538
My Journey Toward Enlightenment: U.S. Patents Cannabinoids as antioxidants and neuroprotectants
A particular disclosed class of cannabinoids useful as neuroprotective antioxidants is formula (I) wherein the R group is ... 6410588 Use of cannabinoids as anti-inflammatory agents June 2002. Feldmann et al. ...http://myjourneytowardenlightenment.blogspot.com/2012/07/us-patent-for-cannabinoids.html
J147 | CAS#1146963-51-0 | neuroprotective and neurotrophic compound | MedKoo
J147 is a potent neuroprotective and neurotrophic compound. J147 protects against neurotoxicity in cortical neurons in vitro ( ... The first synthesis of [11C]J147, a new potential PET agent for imaging of Alzheimer's disease. Bioorg Med Chem Lett. 2013 Jan ... 4: Chiruta C, Zhao Y, Tang F, Wang T, Schubert D. Metabolism of a potent neuroprotective hydrazide. Bioorg Med Chem. 2013 May ... Description: J147 is a potent neuroprotective and neurotrophic compound. J147 protects against neurotoxicity in cortical ...http://www.medkoo.com/products/6843
USE OF MEDICATIONS WITH NEUROPROTECTIVE PROPERTIES TO PREVENT OR REDUCE THE RISK OF ISCHEMIA-REPERFUSION INJURY IN A SUBJECT -...
... reperfusion injury and chronic intermittent hypoxia related injury through administering a neuroprotective compound. A subject ... dispersing agent, suspending agent, diluent, excipient, thickening agent, solvent or encapsulating material, involved in ... Hence, a neuroprotective compound can be coadministered with at least one other therapeutically active agent in the same ... dispersing agents, suspending agents, thickening agents, and/or excipients. The pharmaceutical composition facilitates ...http://www.sumobrain.com/patents/wipo/Use-medications-with-neuroprotective-properties/WO2017062974A1.html
Marine Drugs | Free Full-Text | Neuroprotective Properties of Chitosan and Its Derivatives | Notes
However, considering the side effects of synthetic neuroprotective agents, the search for natural neuroprotective agents has ... Neuroprotection could be achieved through several classes of natural and synthetic neuroprotective agents. ... Recently, an increasing number of studies have identified neuroprotective properties of chitosan and its derivatives; however, ... Hence, the objective of this review is to discuss neuroprotective properties of chitosan and its derivatives. ...http://www.mdpi.com/1660-3397/8/7/2117/notes
Melatonin, Neuroprotective Agents and Antidepressant Therapy | SpringerLink
Melatonin, a Neuroprotective Agent: Relevance for Stress-Induced Neuropsychiatric Disorders Piyarat Govitrapong, Kasima ... Melatonin as a Novel Therapeutic Agent Against Chemical Warfare Agents René Pita, Eva Ramos, José Luis Marco-Contelles, ... The Role of Arrestins in the Neuroprotective Effects of Antidepressant Drugs Sofia Avissar, Moran Golan, Valeria Feinshtein, ... Many antidepressants that are in clinical use today including the recently introduced novel agents like agomelatine or other ...https://link.springer.com/book/10.1007/978-81-322-2803-5
Neuroprotective Agents | Kosterlitz Centre for Therapeutics | The University of Aberdeen
Home › Kosterlitz Projects › Neuroprotective Agents We have identified a series of novel compounds which protect against ...https://www.abdn.ac.uk/kosterlitz/projects/Neuroprotective-Agents/
Bee Venom as a Neuroprotective Agent in Parkinson's Disease | Parkinson's Disease
Bee Venom as a Neuroprotective Agent in Parkinson's Disease. Rapid Response Innovation Awards, 2008. ...https://www.michaeljfox.org/foundation/grant-detail.php?grant_id=462
Pharmaceuticals | Free Full-Text | Cell Permeable Peptides: A Promising Tool to Deliver Neuroprotective Agents in the Brain
In fact, many bioactive cargoes have neuroprotective properties, and due to their ability to block protein-protein interactions ... Cell Permeable Peptides: A Promising Tool to Deliver Neuroprotective Agents in the Brain. Xanthi Antoniou. ... "Cell Permeable Peptides: A Promising Tool to Deliver Neuroprotective Agents in the Brain." Pharmaceuticals 3, no. 2: 379-392. ... Antoniou, X.; Borsello, T. Cell Permeable Peptides: A Promising Tool to Deliver Neuroprotective Agents in the Brain. ...http://www.mdpi.com/1424-8247/3/2/379
Discovery and Development of Neuroprotective Agents from Natural Products eBook by - 9780128097694 | Rakuten Kobo
Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal ag... ... Read Discovery and Development of Neuroprotective Agents from Natural Products by with Rakuten Kobo. ... Discovery and Development of Neuroprotective Agents from Natural Products draws together global research on medicinal agents ... Discovery and Development of Neuroprotective Agents from Natural Products by Natural Product Drug Discovery ...https://www.kobo.com/us/en/ebook/discovery-and-development-of-neuroprotective-agents-from-natural-products
Neuroprotective Agents: Ninth International Conference - Russell J. Andrews; William Slikker; Bruce Trembly; Tucker A....
Features proceedings of the Ninth International Conference on Neuroprotective Agents * Part of the Annals of the New York ... Neuroprotective Agents: Ninth International Conference (Paperback). Russell J. Andrews. William Slikker. Bruce Trembly. Tucker ... Features proceedings of the Ninth International Conference on Neuroprotective Agents * Part of the Annals of the New York ...http://www.foyles.co.uk/witem/science-mathematics/neuroprotective-agents-ninth,russell-j-andrews-william-slikker-bruce-trembly-tucker-a-patterson-9781573317771
Noopept - Neuroprotective agent
Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis ... Noopept - Neuroprotective agent Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model ... Secret Service Agent Sues Oklahoma Narcotics Agent for Muscle Profiling. By Prince in forum Muscle Central ... Moreover, neuroprotective properties of noopept likely include its ability to decrease tau phosphorylation and to restore the ...http://www.ironmagazineforums.com/threads/201774-Noopept-Neuroprotective-agent?mode=hybrid
The Feasibility of Neuroprotective Agent Administration by Pre-hospital Personnel in an Urban Setting | Stroke
The Feasibility of Neuroprotective Agent Administration by Pre-hospital Personnel in an Urban Setting. Todd J Crocco, Travis C ... The Feasibility of Neuroprotective Agent Administration by Pre-hospital Personnel in an Urban Setting ... The Feasibility of Neuroprotective Agent Administration by Pre-hospital Personnel in an Urban Setting ... The Feasibility of Neuroprotective Agent Administration by Pre-hospital Personnel in an Urban Setting ...http://stroke.ahajournals.org/content/32/Suppl_1/369.4
Observation periods of 1 year for clinical trials of neuroprotective agents in glaucoma are feasible | IOVS | ARVO Journals
A clinical trial, with a VF outcome and an observation period of only 12 months, for a neuroprotective agent in patients on IOP ... The assumed study design is a placebo-controlled trial of a neuroprotective agent, with all patients taking latanoprost in ... Observation periods of 1 year for clinical trials of neuroprotective agents in glaucoma are feasible ... Observation periods of 1 year for clinical trials of neuroprotective agents in glaucoma are feasible ...http://iovs.arvojournals.org/article.aspx?articleid=2268984
Jumex - Dopaminergics, Neuroprotective Agents, Antiparkinson Agents, Antidyskinetics, Central Nervous...
Dopamine is an essential chemical that occurs in many parts of the body. It is the premature degradation of dopamine that results in the symptoms of Parkinson's disease. Monoamine oxidase (MAO) is an enzyme which accelerates the breakdown of dopamine. Selegiline can prolong the effects of dopamine in the brain by preventing its breakdown through seletively blocking MAO. It also may prevent the removal of dopamine between nerve endings and enhance release of dopamine from nerve cells ...http://pharmacycode.com/Jumex.html
Recombinant human stress protein Hsp70 as a perspective neuroprotective agent | 4science
Recombinant human stress protein Hsp70 as a perspective neuroprotective agent. Рус Eng ... To test possible neuroprotective effect of recombinant human Hsp70 we used two separate mouse models of AD-like pathology, ... Taken together, our findings establish exogenous human Hsp70 as a practical pharmacological agent for the treatment of various ... Various data suggest that Hsp70 and other molecular chaperones function as a complex neuroprotective system, which fails in the ...https://4science.ru/events/sf2016/theses/137f247c6a154b30b8a9ea9ab4fdd49d
Predni N Tablinen - Neuroprotective Agents, Glucocorticoids, Antiemetics, Anti-inflammatory Agents, ...
... are synthetic glucocorticoids used as antiinflammatory or immunosuppressive agents. ...http://pharmacycode.com/Predni_N_Tablinen.html
Synthesis and Biological Evaluation of Amidine, Guanidine, and Thiourea Derivatives of 2-Amino(6-trifluoromethoxy)benzothiazole...
... benzothiazole as Neuroprotective Agents Potentially Useful in Brain Diseases ...https://www.infona.pl/resource/bwmeta1.element.acs-doi-10_1021_jm901375r
Poulsen Studies Neuroprotective Agent for Traumatic Brain Injury - Jacobs School of Medicine and Biomedical Sciences -...
"The development of novel neuroprotective agents has proven difficult, as TBI represents a heterologous injury," he says. ... 966,000 in private funding to further study a novel neuroprotective agent for moderate-to-severe traumatic brain injury (TBI). ... "The company is focused on the development of safe and effective neuroprotective treatments for stroke and TBI," Poulsen says. ... but Poulsen says it may also may exert a neuroprotective effect by reducing neuroinflammation after TBI. ...http://medicine.buffalo.edu/news_and_events/news.host.html/content/shared/smbs/news/2017/03/poulsen-phenoxybenzamine-tbi-6711.detail.html
IJMS | Free Full-Text | Regenerative Medicine for Epilepsy: From Basic Research to Clinical Application | HTML
Subsequently, we discuss the concepts of regenerative medicine including cell therapy, neuroprotective agents, and electrical ... 2.2.2. Neuroprotective Agents. Many neurotrophic factors have been explored as therapeutic modalities against TLE. ... We envision that cell therapy, novel neuroprotective agents, and electrical stimulation epitomize the new frontiers of ... Subsequently, we discuss the concepts of regenerative medicine including cell therapy, neuroprotective agents, and electrical ...http://www.mdpi.com/1422-0067/14/12/23390/htm
Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: A pilot...
Ketamine as a neuroprotective and anti-inflammatory agent in children undergoing surgery on cardiopulmonary bypass: A pilot ...http://www.biomedsearch.com/nih/Ketamine-as-neuroprotective-anti-inflammatory/21926656.html
Book Series: International Review of Neurobiology
Neuroprotective Agents and Cerebral Ischaemia Published: 26th November 1996 Serial Volume Editors: Richard Green Alan Cross ...https://www.elsevier.com/books/book-series/international-review-of-neurobiology
Molecular and Cellular Biology of Neuroprotection in the CNS | SpringerLink
Neurotrophic Factors as Neuroprotective Agents. * Front Matter Pages 301-301 PDF. * Neurotrophins ... Neuroprotective Activity of Metabotropic Glutamate Receptor Ligands Peter J. Flor, Giuseppe Battaglia, Ferdinando Nicoletti, ... Na+Channels and Ca2+ Channels of the Cell Membrane as Targets of Neuroprotective Substances ...https://link.springer.com/book/10.1007/978-1-4615-0123-7
Frontiers | Role of mTORC1 Controlling Proteostasis after Brain Ischemia | Neuroscience
In addition, neuroprotective intervention either by estradiol or by specific AT2R agonists shows an important regulatory role ... Some Neuroprotective Agents Regulate mTOR Activity. Many data support the hypothesis that PI3K-Akt-mTORC1 represents a major ... "Some neuroprotective agents regulates mTOR Activity"; FW, "Conclusion." The figures has been designed and made by MV, FW, and ... An important neuroprotective element used in ischemia models is estradiol, which has been reputed to reduce ischemic damage ...https://www.frontiersin.org/articles/10.3389/fnins.2018.00060/full
IJMS | Free Full-Text | Neuroprotective and Therapeutic Strategies against Parkinson's Disease: Recent Perspectives | HTML
Here, we will discuss diverse mechanisms that are involved in PD, neuroprotective and therapeutic strategies currently in ... Several neuroprotective agents that target different pathways have been proposed. These putative neuroprotective agents are ... Thus, conceivably, agents that can inhibit the apoptotic or cell death pathways could be used as neuroprotective agents in PD. ... Thus, further research is necessary to develop such an agent that will qualify as a "neuroprotective" agent that will mitigate ...http://www.mdpi.com/1422-0067/17/6/904/htm