Extracellular vesicle concentrations of glial fibrillary acidic protein and neurofilament light measured 1 year after traumatic...
The multifaceted role of neurofilament light chain protein in non-primary neurological diseases
In particular, neurofilament light chain protein is associated with the degree of neurological impairment and outcome in ... In particular, neurofilament light chain protein is associated with the degree of neurological impairment and outcome in ... The multifaceted role of neurofilament light chain protein in non-primary neurological diseases. Abu-Rumeileh, Samir;Abdelhak, ... review the role of neurofilament light chain protein as a CSF and blood biomarker in non-primary neurological conditions within ...
Zentrum für klinische Neurowissenschaften Dresden - Neurofilaments - Small proteins of physiological significance and...
Autoimmunity against neurofilament protein and its possible association with HLA-DRB1*1502 allele in glaucoma<...
We identified neurofilament protein and the prevalence of anti-bovine neurofilament light subunit (NF-L) autoantibodies in ... We identified neurofilament protein and the prevalence of anti-bovine neurofilament light subunit (NF-L) autoantibodies in ... We identified neurofilament protein and the prevalence of anti-bovine neurofilament light subunit (NF-L) autoantibodies in ... We identified neurofilament protein and the prevalence of anti-bovine neurofilament light subunit (NF-L) autoantibodies in ...
Neurofilament light polypeptide - Wikipedia
... notably the tau and neurofilament light chain proteins. Xu Z, Henderson RD, David M, McCombe PA (2016). "Neurofilaments as ... The NF-L protein is encoded by the NEFL gene. Neurofilament light chain is a biomarker that can be measured with immunoassays ... Neurofilament light polypeptide has been shown to interact with: MAP2, Protein kinase N1, and TSC1. GRCh38: Ensembl release 89 ... Chin SS, Liem RK (December 1989). "Expression of rat neurofilament proteins NF-L and NF-M in transfected non-neuronal cells". ...
Serum Neurofilament Light Chain as a Marker of Progression in Parkinson's Disease : Long-Term Observation and Implications of...
biomarkers, dementia, mortality, neurofilament proteins, Parkinsons disease, prognosis. in Journal of Parkinsons Disease. ... neurofilament proteins; Parkinsons disease; prognosis}}, language = {{eng}}, number = {{2}}, pages = {{571--584}}, publisher ... Serum Neurofilament Light Chain as a Marker of Progression in Parkinsons Disease : Long-Term Observation and Implications of ... Objective: To examine how serum neurofilament light chain (S-NfL) alone or combined with clinical classifications predicts PD ...
Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntington's disease patients
Furthermore, the level of mHTT was associated with the concentrations of tau and neurofilament light chain in the CSF, ... Quantification of mutant huntingtin protein in cerebrospinal fluid from Huntingtons disease patients J Clin Invest. 2015 May; ... Background: Quantification of disease-associated proteins in the cerebrospinal fluid (CSF) has been critical for the study and ... treatment of several neurodegenerative disorders; however, mutant huntingtin protein (mHTT), the cause of Huntingtons disease ...
Utility of Serum Neurofilament Light Protein as a Biomarker in Traumatic Brain Injury, IJSR, Call for Papers, Online Journal
Utility of Serum Neurofilament Light Protein as a Biomarker in Traumatic Brain Injury. Shalini Pasupuleti , Satish Kumar Putta ... Shalini Pasupuleti, Satish Kumar Putta, Vamsi Krishna Yerramneni, Ashima Sharma, "Utility of Serum Neurofilament Light Protein ... All the participants were assessed for serum levels of Neurofilament Light protein (NFL) and S100B. Results: Serum NFL and ... Keywords: Traumatic brain injury, Neurofilament light protein, s100b, axonal injury, orthotrauma patients ...
Pathology of Expansile Astrocytomas: Overview, Pilocytic Astrocytoma, Pilomyxoid Astrocytoma
Neurofilament protein localization may be a useful way to distinguish this tumor from giant cell glioblastomas. [39] CD34 has ... None of the tumors were immunoreactive for synaptophysin or neurofilament protein. Another study indicated that these tumors ... Pleomorphic xanthoastrocytoma has a strong tendency to show nonphosphorylated neurofilament protein immunoreactive cells. ... and the neuronal markers neurofilament protein and synaptophysin. [96] The phenotypic ambiguity also extends to the cortical ...
Plasma glial fibrillary acidic protein and neurofilament light chain for the diagnostic and prognostic evaluation of...
In this study, we investigated the diagnostic performance of plasma GFAP (pGFAP), plasma neurofilament light chain (pNfL) and ... Studies of glial fibrillary acidic protein (GFAP), an astrocytic damage marker, may help advance our understanding of different ... Glial fibrillary acidic protein and protein S-100B: different concentration pattern of glial proteins in cerebrospinal fluid of ... Zhu, N., Santos-Santos, M., Illán-Gala, I. et al. Plasma glial fibrillary acidic protein and neurofilament light chain for the ...
KCC3 axonopathy: neuropathological features in the central and peripheral nervous system | Modern Pathology
... and using an antibody against neurofilament protein (h, case 7). Neuraxonal spheroids were either filled with neurofilament- ... Immunostaining with an antibody against neurofilament protein demonstrates much larger spheroids in the oculomotor nerve than ... or immunostained with an antibody against neurofilament protein (b, d, f, h). The centrum semiovale (a, b, case 4) and the ... Dispersed neurofilament protein and flocculent densities filled the axoplasm in other locations (Figure 9a). ...
A blood test shows MS worsening 1 to 2 years before it happens | ScienceDaily
Neurofilament light chain as a biomarker in neurological disorders | Journal of Neurology, Neurosurgery & Psychiatry
The following search terms were used: neurofilament light, neurofilament light chain, neurofilament light protein, NfL ... Serum neurofilament light protein predicts clinical outcome in traumatic brain injury. Sci Rep 2016;6:1-9.doi:10.1038/srep36791 ... CSF neurofilament proteins in the differential diagnosis of dementia. J Neurol Neurosurg Psychiatry 2007;78:936-8.doi:10.1136/ ... Serum neurofilament light protein as a marker for diffuse axonal injury: results from a case series study. J Neurotrauma 2017; ...
Thomas Shea | Biological Sciences | Kennedy College of Sciences | UMass Lowell
Yabe, J.T., Jung, C., Chan, W.K., Shea, T.B. (2000). Phospho-Dependent Association of Neurofilament Proteins with Kinesin in ... Lee, S., Sunil, N., Shea, T.B. (2011). C-Terminal Neurofilament Phosphorylation Fosters Neurofilament-Neurofilament ... Phosphorylated 200kD neurofilament protein in NB2a/d1 perikarya - 19th Annual Meeting of the American Society for ... Expression of neurofilament proteins by differentiated neuroblastoma cells., 1986 - Eunice Kennedy Shriver Center for Mental ...
Neurofilament L Antibody from ST JOHN'S LABORATORY
Helena Brisby | University of Gothenburg
Loss of Mitogen-Activated Protein Kinase Kinase Kinase 4 (MAP3K4) Reveals a Requirement for MAPK Signalling in Mouse Sex...
2004) Mitogen-activated protein kinase regulates neurofilament axonal transport. J Cell Sci 117: 4629-4642. * View Article ... mitogen-activated protein kinase; MAP3K4, mitogen-activated protein kinase kinase kinase 4; PECAM, platelet/endothelial cell ... at amino acid position 382 of the 1,597 amino acid MAP3K4 protein. The predicted truncated protein lacks the critical kinase ... Analysis of SF1, FOXL2, and FGFR2 protein expression in XY control and byg/byg gonads at 11.5 dpc. (A, B) Transverse section ...
Staff | Max Planck Institute for Human Cognitive and Brain Sciences
Plus it
1995) Neurofilament protein defines regional patterns of cortical organization in the macaque monkey visual system: a ... 1991) A subpopulation of corticocortical neurons is distinguished by somatodendritic distribution of neurofilament protein. ... also regulate cell hypertrophy by inducing protein synthesis, translation initiation factors, and nucleolar structural proteins ... Many morphogenetic proteins, such as members of thewingless/Wnt and Hedgehog/Shh families, regulate cell growth as well as ...
The Cytoskeleton
Neurofilaments and Neurofilament Proteins in Health and Disease. Aidong Yuan, Mala V. Rao, Veeranna, and Ralph A. Nixon. ... Actin and Actin-Binding Proteins. Thomas D. Pollard. Microtubules and Microtubule-Associated Proteins. Holly V. Goodson and ... Motor Proteins. H. Lee Sweeney and Erika L.F. Holzbaur. Cytoskeleton Integrators: The Spectrin Superfamily. Ronald K.H. Liem. ... Type III Intermediate Filaments Desmin, Glial Fibrillary Acidic Protein (GFAP), Vimentin, and Peripherin. Elly M. Hol and ...
The Cytoskeleton
Neurofilaments and Neurofilament Proteins in Health and Disease. Aidong Yuan, Mala V. Rao, Veeranna, and Ralph A. Nixon. ... Actin and Actin-Binding Proteins. Thomas D. Pollard. Microtubules and Microtubule-Associated Proteins. Holly V. Goodson and ... Motor Proteins. H. Lee Sweeney and Erika L.F. Holzbaur. Cytoskeleton Integrators: The Spectrin Superfamily. Ronald K.H. Liem. ... Type III Intermediate Filaments Desmin, Glial Fibrillary Acidic Protein (GFAP), Vimentin, and Peripherin. Elly M. Hol and ...
Dementia Pathology: Dementia, Alzheimer Disease, Vascular Dementia
Multiple other FTDs exist; some have characteristic neuronal inclusions (eg, neurofilament, TAR DNA binding protein-43), ... the transmitting agent is a misfolded protein called the prion protein, capable of causing native, normally folded protein to ... Lewy bodies comprise a number of different aggregated proteins, the most diagnostically useful of which is alpha-synuclein. [20 ... Amyloid angiopathy can be identified using stains for amyloidal protein (Congo red, thioflavin-S), or immunohistochemical ...
Frontiers | Extended Postnatal Brain Development in the Longest-Lived Rodent: Prolonged Maintenance of Neotenous Traits in the...
... and synaptic protein expression continues to change throughout the first 3 years of life. Intriguingly, NMR axonal composition ... and synaptic protein expression continues to change throughout the first three years of life. Intriguingly, NMR axonal ... At 4 months of age, NMR brains reach 90% of adult size with stable neuronal cytostructural protein expression whereas myelin ... At four months of age, NMR brains reach 90% of adult size with stable neuronal cytostructural protein expression whereas myelin ...
Chicken Neurofilament NF ELISA Kit - Gentaur.com
... - Product info ... Neurofilament H, 200kD (NF-H, NFH, 200kD Neurofilament Protein ... neurofilament light polypeptide; neurofilament subunit NF-L; neurofilament triplet L protein; neurofilament protein, light ... Neurofilament 3, NEF3, Neurofilament Medium Polypeptide, Neurofilament Protein Medium, NEFM, Neurofilament Triplet M Protein, ... Neurofilament 3, NEF3, Neurofilament Medium Polypeptide, Neurofilament Protein Medium, NEFM, Neurofilament Triplet M Protein, ...
Adrenal Gland | College of American Pathologists
Anders Wallin | Göteborgs universitet
Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis. ... Differential Impact of Neurofilament Light Subunit on Cognition and Functional Outcome in Memory Clinic Patients with and ... Serum but not cerebrospinal fluid levels of insulin-like growth factor-I (IGF-I) and IGF-binding protein-3 (IGFBP-3) are ... Discriminatory Analysis of Biochip-Derived Protein Patterns in CSF and Plasma in Neurodegenerative Diseases. ...
Neurotoxins: Definition, Epidemiology, Etiology
Both carbon disulfide and n-hexane are thought to cause toxicity by crosslinking proteins, including neurofilaments. [14] ... Differential protein expression of hippocampal cells associated with heavy metals (Pb, As, and MeHg) neurotoxicity: Deepening ... Furthermore, carbon monoxide binds to other iron-containing proteins such as myoglobin, cytochrome p450, catalase, peroxidase, ... Carbon disulfide poisoning causes a peripheral nerve axonopathy with axonal swellings, with accumulation of neurofilaments and ...
Aluminum salts final content: chapter 2.4 - Canada.ca
alteration of phosphorylation level of neurofilaments, including phosphorylation of tau-protein, and resulting neurofibrillary ... Johnson et al. (1992) observed decreased levels of cytoskeletal proteins (microtubule associated protein-2, spectrin) in the ... delayed expression of a phosphorylated neurofilament protein (Poulos et al. 1996), differential effects on choline ... Johnson et al. (1992) reported decreased levels of microtubule associated protein-2 in the brains of rat pups exposed eight ...