Neural crest induction by paraxial mesoderm in Xenopus embryos requires FGF signals | Development
... effects on neural crest formation were parallel to altered mesoderm or neural development. However, neural and neural crest ... Neural crest induction and neural plate posteriorization. Neural crest induction is achieved experimentally by combining the ... to evoke neural crest formation even if the robust induction of neural crest markers and further development of neural crest ... FGF8 enhances neural crest formation in embryos and is sufficient to induce neural crest markers in explants. As FGF8 has ...http://dev.biologists.org/content/130/14/3111
Current projects - THE URIBE LAB
The ENS arises from "vagal" neural crest stem cells that originate from the post-otic dorsal neural tube. Vagal neural crest ... How does a neural crest cell become a particular derivative?. Neural crest cells are a group of multipotent stem cell that ... 4. To understand how neural crest-derived cancers form from the vagal neural crest in vivo.. ... 3. Construction of the signaling-level regulatory network that governs vagal neural crest development and neural crest ...https://www.uribelabrice.com/current-projects.html
Fate maps of neural crest and mesoderm in the mammalian eye
... Gage, PJ; Rhoades, W; Prucka, SK and Hjalt, Tord LU (2005) In ... In the present study, the first long-term fate maps are presented for neural crest and mesoderm in a mammalian eye. METHODS. ... In the present study, the first long-term fate maps are presented for neural crest and mesoderm in a mammalian eye. METHODS. ... The results established that fates of neural crest and mesoderm in mice were similar to but not identical with those in birds. ...https://lup.lub.lu.se/search/publication/216539
Semaphorin/neuropilin signaling influences the positioning of migratory neural crest cells within the hindbrain region of the...
... the receptor components essential for Semaphorin activity by neural crest cells suggests a function in restricting neural crest ... we define a role for both Semaphorins in the maintenance of neural crest cell streams in proximity to the neural tube. ... Although the streaming of neural crest cells is known to involve signals derived from the neuroepithelium, the molecular ... The loss or misguidance of specific neural crest cell populations after changes in Semaphorin signaling also affects the ...https://www.dpag.ox.ac.uk/publications/251911
Int J Dev Biol - Trunk neural crest cells: formation, migration and beyond
The trunk neural crest has long been considered of particular significance. First, it has been held that the trunk neural crest ... Second, the trunk neural crest additionally has skeletal potential. However, it has been demonstrated that a key role of the ... Although trunk NCCs have a limited capacity for self-renewal, sometimes they become neural-crest-derived tumor cells and reveal ... need to translate the wealth of data from animal studies to the clinical area in order to develop treatments for neural crest- ...http://www.ijdb.ehu.es/web/paper/160408gv/trunk-neural-crest-cells-formation-migration-and-beyond
PSRC - APPLICATION OF ZEBRAFISH NEURAL CREST CULTURE ASSAYS TO ELUCIDATE STEM CELL PROPERTIES
Purpose: Vertebrate neural crest development depends on pluripotent, migratory neural crest (NC) cells. Isolation and culture ... APPLICATION OF ZEBRAFISH NEURAL CREST CULTURE ASSAYS TO ELUCIDATE STEM CELL PROPERTIES. Presenter: Beste Kinikoglu, PhD. Co- ... Conclusions: In this study we established a novel in vitro neural crest system and methods for isolating and culturing these ...http://www.ps-rc.org/meeting/abstracts/2013/78.cgi
Differentiation of Neural-Crest-Derived Intermediate Pluripotent Progenitors into Committed Periodontal Populations Involves...
Differentiation of Neural-Crest-Derived Intermediate Pluripotent Progenitors into Committed Periodontal Populations Involves ... Differentiation of Neural-Crest-Derived Intermediate Pluripotent Progenitors into Committed Periodontal Populations Involves ...http://www.omicsoft.com/publications/2014/2/22/differentiation-of-neural-crest-derived-intermediate-pluripotent-progenitors-into-committed-periodontal-populations-involves-unique-molecular-signature-changes-cohort-shifts-and-
Fate mapping the chondrichthyan neural crest. The neural crest is an embryonic cell population that gives rise to much of the ... Neural crest fate maps have been generated for a number of osteichthyan model systems (e.g. mouse, chick, frog and zebrafish). ... This work will allow us to infer primitive fates of neural crest cells in the last common ancestor of jawed vertebrates (e.g. ... mesodermal contributions to the craniofacial skeleton and pectoral girdle, and the skeletogenic potential of trunk neural crest ...https://www.zoo.cam.ac.uk/research-groups/gillis-lab/research
Axonal pathfinding and neural crest cells
... Neural crest cells form at the anterior end of the neural plate, at the border of ... Migration of Neural Crest Cells. Beginning Migration. When Neural Crest Cells begin to migrate, they lose their adhesion to the ... Neural crest cells were transplanted from one position in the body to another position. They developed into neural crest ... What are the derivatives of neural crest?. Neural crest cells form dorsal root ganglia (sensory neurons) and melanocytes ( ...https://studentreader.com/7393G/axonal-pathfinding-neural-crest-cells/
Animal models for studying neural crest development: is the mouse different? | Development
... neural crest domain but rather marks dorsal neural stem cells that contribute to both central nervous system and neural crest ... even though Wnt1-Cre lineage tracing labels most neural crest cells in mice, if a gene of interest or prospective neural crest ... the Wnt1-Cre line might be inappropriate to study early stages of neural crest development, as the initiation of neural crest ... perhaps accompanied by differences in the neural crest GRN. However, given that the expression and function of neural crest GRN ...http://dev.biologists.org/content/142/9/1555.long
The role of the non-canonical Wnt-planar cell polarity pathway in neural crest migration | Biochemical Journal
Neural crest cells exhibit collective cell migration, moving in streams of high directionality. The migratory neural crest ... pathway plays a major role in neural crest migration. PCP signalling controls contact inhibition of locomotion between neural ... The role of the non-canonical Wnt-planar cell polarity pathway in neural crest migration. Roberto Mayor, Eric Theveneau ... The neural crest is an embryonic stem cell population whose migratory behaviour has been likened to malignant invasion. The ...http://www.biochemj.org/content/457/1/19
Human Fetal Keratocytes Have Multipotent Characteristics in the Developing Avian Embryo
... keratocytes injected along the neural crest pathway were localized adjacent to HNK-1-positive migratory host neural crest cells ... The objective of this study is to examine the potential of human fetal keratocytes (HFKs) to differentiate into neural crest- ... These results show that HFKs retain the ability to differentiate into some neural crest-derived tissues. Their ability to ... The HuNu-positive cells transformed into neural crest derivatives such as smooth muscle in cranial blood vessels, stromal ...https://scholarship.rice.edu/handle/1911/75339
Dissimilar regulation of cell differentiation in mesencephalic (cranial) and sacral (trunk) neural crest cells in vitro.
Depending on the cranial-caudal level of their origin, different populations of neural crest cells exhibit ... During development neural crest cells give rise to a wide variety of specialized cell types in response to cytokines from ... cranial neural crest cells differ dramatically from the trunk neural crest cells in how they respond to specific extracellular ... During development neural crest cells give rise to a wide variety of specialized cell types in response to cytokines from ...http://www.biomedsearch.com/nih/Dissimilar-regulation-cell-differentiation-in/12925584.html
The MADS box transcription factor MEF2C regulates melanocyte development and is a direct transcriptional target and partner of...
... directs expression to the nascent neural crest adjacent to the neural folds at E8.5 (A) and in neural crest derivatives, ... Neural crest cells are multipotent progenitor cells that originate from the dorsal neural tube at the border of the neural ... To place Mef2c into a pathway for neural crest and melanocyte development, we next examined the Mef2c-F1 neural crest enhancer ... MEF2C function is also required in the neural crest or in neural crest-derived cells for melanocyte function or differentiation ...http://dev.biologists.org/content/138/12/2555
Neural Crest Stem Cells/Progenitors and Their Potential Applications in Disease Therapies | MedCrave
NCSCs: Neural Crest Stem Cells; NCCs: Neural Crest Cells; EMT: Epithelial-Mesenchymal Transition; PNS: Peripheral Nervous ... Kalcheim L Da (1999) The Neural Crest. Cambridge University Press, India.. *Mayor R, Theveneau E (2013) The neural crest. ... Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest ... Clonal analysis of the avian neural crest: migration and maturation of mixed neural crest clones injected into host chicken ...http://googlescholar.medcraveonline.com/scholars/article_fulltext/4294
Growth factors regulating neural crest cell fate decisions - Zurich Open Repository and Archive
Because of its unique ability to generate a wide variety of both neural and nonneural derivatives, the neural crest is an ideal ... Because of its unique ability to generate a wide variety of both neural and nonneural derivatives, the neural crest is an ideal ... Neural crest cells have to integrate these signals to ensure the generation of appropriate numbers of differentiating progeny. ... Neural crest cells have to integrate these signals to ensure the generation of appropriate numbers of differentiating progeny. ...http://www.zora.uzh.ch/id/eprint/116000/
Disc1 regulates foxd3 and sox10 expression, affecting neural crest migration and differentiation | Development
Knight, R. D. and Schilling, T. F. (2006). Cranial neural crest and development of the head skeleton. In Neural crest induction ... neural crest migration and the differentiation of some neural crest derivatives (Cheung et al., 2005; Lister et al., 2006; ... but delayed neural crest migration and depletion of certain neural crest derivatives (Lister et al., 2006; Stewart et al., 2006 ... The mother superior mutation ablates foxd3 activity in neural crest progenitor cells and depletes neural crest derivatives in ...http://dev.biologists.org/content/136/15/2623
meis1 - Homeobox protein Meis1 - Xenopus laevis (African clawed frog) - meis1 gene & protein
... to specify neural crest cell fate. Binds to a highly conserved region in the promoter of the neural crest marker gene zic3. ... Induces expression of a number of neural crest marker genes as part of a heterodimer with isoform b of pbx1, ... to specify neural crest cell fate. Binds to a highly conserved region in the promoter of the neural crest marker gene zic3.3 ... dorsal portion of the neural tube, and neural crest-derived branchial arches. Widely expressed in the adult with highest levels ...http://www.uniprot.org/uniprot/P79937
Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube |...
... slug-expressing neural crest cells. Thus, BMPs play multiple and discernible roles at sequential stages of neural crest ... For neural crest cells to engage in migration, it is necessary that epithelial premigratory crest cells convert into mesenchyme ... Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube ... Regulation of the onset of neural crest migration by coordinated activity of BMP4 and Noggin in the dorsal neural tube ...http://dev.biologists.org/content/126/21/4749
Cardiac neural crest cells - Wikipedia
Cardiac neural crest cells (CNCCs) are a type of neural crest cells that migrate to the circumpharyngeal ridge (an arc-shape ... In 2005, Tomita transplanted neural crest stem cells from mammal hearts to the neural crest of chick embryos. These CNCCs were ... and for differentiation of neural crest cells to smooth muscle cells of the aortic arch arteries. In neural crest-specific Alk2 ... Neural crest cells are a group of temporary, multipotent (can give rise to some other types of cells but not all) cells that ...https://en.wikipedia.org/wiki/Cardiac_neural_crest_cells
neural crest markers
... Jim Du jdu at u.washington.edu Sat Aug 19 18:25:45 EST 1995 *Previous message: Larval feeding habits ... Does anyone have a good marker (cDNA or antibody) for staining of trunk neural crest in the zebrafish embryos (11 hrs to 24 hrs ...http://www.bio.net/bionet/mm/zbrafish/1995-August/003151.html
What Are Neural Crest Cells?
Neural crest cells are a type of migratory cells that are responsible for the formation of many different anatomical structures ... and vagal neural crest cells.. During embryonic development, the neural crest is formed shortly before the neural tube - the ... the neural crest cells migrate through the cranium and settle into the pharyngeal arches. Now called cranial neural crest cells ... Some of the neural crest cells will continue to travel to other parts of the body. Ganglia within the digestive system are ...http://www.wisegeek.com/what-are-neural-crest-cells.htm
Neural Crest: Origin, Migration and Differentiation
The neural crest is a population of cells that emigrates from the dorsal neural tube during early embryogenesis and migrates ... when the neural crest cells are beginning to migrate. At the neural plate stage, neural crest cells are not yet specified, but ... neural crest cells (NC) are induced to form from the edges of the neural plate (or neural folds). N, notochord; NC, neural ... stages of neural crest migration. Initially, neural crest cells (NC) migrate ventrally between the neural tube and somite (S). ...http://www.els.net/WileyCDA/ElsArticle/refId-a0000786.html
Neural Crest Induction and Differentiation | Jean-Pierre Saint-Jeannet | Springer
Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all ... Neural Crest Induction and Differentiation. Editors. * Jean-Pierre Saint-Jeannet Series Title. Advances in Experimental ... Neural Crest Induction and Differentiation, written by an international panel of recognized leaders in the field, discusses all ... to the pathologies associated with abnormal neural crest development and function. Each chapter provides an invaluable resource ...http://www.springer.com/us/book/9780387351360
Infantile hemangiomas exhibit neural crest and pericyte markers. - PubMed - NCBI
Infantile hemangiomas exhibit neural crest and pericyte markers.. Spock CL1, Tom LK, Canadas K, Sue GR, Sawh-Martinez R, Maier ... We observed that neural crest markers such as NG2 and nestin were expressed in the hemangioma samples, in addition tomultiple ... We analyzed a number of cell markers using these methods, including cell markers for the neural crest, pericytes, endothelial ... Infantile hemangiomas exhibit neural crest and pericyte markers. [Ann Plast Surg. 2015] ...https://www.ncbi.nlm.nih.gov/pubmed?term=24401806