Stem Cells, Nonproliferating Cells, and Their Kinetics in Normal and Neoplastic Tissues | SpringerLink
... it seems appropriate to review critically some principal aspects of Cell. and tissue kinetics as they... ... Potmesil M., LoBue J., Goldfeder A. (1977) Stem Cells, Nonproliferating Cells, and Their Kinetics in Normal and Neoplastic ... Stem Cells, Nonproliferating Cells, and Their Kinetics in Normal and Neoplastic Tissues. ... and tissue kinetics as they relate to stem cells, to nonproliferating cells, and to Cell. recruitment into the mitotic cycle. ...https://link.springer.com/chapter/10.1007/978-1-4684-2739-4_9
Pancreatic cancer stem cells: emerging target for designing novel therapy.
... there have been significant advances in the research on cancer stem cells (CSCs). The emerging evidences have demonstrated that ... CSCs and epithelial-mesenchymal transition (EMT)-type cells, which share molecular characteristics ... Neoplastic Stem Cells / drug effects*, metabolism, pathology. Pancreatic Neoplasms / drug therapy*, genetics, pathology. Signal ... In the past few years, there have been significant advances in the research on cancer stem cells (CSCs). The emerging evidences ...http://www.biomedsearch.com/nih/Pancreatic-cancer-stem-cells-Emerging/22445908.html
Evaluation of cancer stem cell migration using compartmentalizing microfluidic devices and live cell imaging.
Neoplastic Stem Cells / pathology*. Single-Cell Analysis / instrumentation*, methods. Tumor Cells, Cultured. ... If required after cell counting, additional stem cell medium is added to the BTSC suspension to give a cell density of 20,000 ... Cancer Stem Cells-Perspectives on Current Status and Future DirectionsAACR Workshop on Cancer Stem Cells. Cancer ResearchYear: ... BTSCs enriched in this manner demonstrate stem cell-like properties, such as expression of stem cell markers (CD133, nestin), ...http://www.biomedsearch.com/nih/Evaluation-cancer-stem-cell-migration/22217858.html
Endometrial Cancer Spheres Show Cancer Stem Cells Phenotype and Preference for Oxidative Metabolism | Springer for Research &...
This study aimed to characterize endometrial cancer regarding cancer stem cells (CSC) markers, regulatory and differentiation ... Endometrial neoplasms Neoplastic stem cells Glucose metabolism Abbreviations. ALDH. aldehyde dehydrogenase. ATCC. American Type ... Comparison of spheroids formed by rat glioma stem cells and neural stem cells reveals differences in glucose metabolism and ... Götte M, Greve B, Kelsch R et al (2011) The adult stem cell marker Musashi-1 modulates endometrial carcinoma cell cycle ...https://rd.springer.com/article/10.1007%2Fs12253-018-0535-0
Differentiation of mammary stem cells in vivo and in vitro.
... and myoepithelial cells, are distinguished by their ultrastructure and by their accumulation of immunocytochemically detectable ... The fully differentiated cells of the rat mammary parenchyma, the ductal epithelial, alveolar, ... Neoplastic Stem Cells / cytology. Rats. Stem Cells / cytology*. Chemical. Reg. No./Substance: 0/Calcium-Binding Proteins ... Under different culture conditions, the epithelial stem cells differentiate along a separate pathway to myoepitheliallike cells ...http://www.biomedsearch.com/nih/Differentiation-mammary-stem-cells-in/2647483.html
2010 « Events « Institute for Genomics and Systems Biology
Normal and Neoplastic Stem Cells. May 3, 2:00pm - 3:00pm. with Irving L. Weissman, M.D. ... Mechanobiological regulation of tumor and stem cell biology in the central nervous system. Mar 18, 2:15pm - 3:15pm. with Sanjay ... Runx1 Function in Hematopoietic Stem Cell Emergence. May 24, 6:00pm - 7:00pm. with Nancy Speck, Ph.D ... Cell polarity, morphogenesis and cancer. Nov 2, 2:00pm - 3:00pm. Department of Surgery with Senthil Muthuswamy, PhD ...http://www.igsb.anl.gov/events/archive/2010/
Expression levels of stem cell genes and activation of | Open-i
Expression levels of stem cell genes and activation of the Wnt/β-catenin pathway in CD24+ cells.(A) mRNA expression levels of ... Gene Expression Regulation, Neoplastic. *Humans. *Matrix Metalloproteinase 2/metabolism. *Matrix Metalloproteinase 9/metabolism ... To examine whether CD24+ cells have intrinsic stem cell properties, we analyzed the expression of five embryonic stem cell ... To examine whether CD24+ cells have intrinsic stem cell properties, we analyzed the expression of five embryonic stem cell ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4067285_pone.0099412.g002&req=4
More than 45% of A549 and H446 cells are cancer initiating cells: evidence from cloning and tumorigenic analyses.
This study was designed to investigate the fraction of cancer stem cells in the A549 and H446 cell lines by cloning and ... Cancer stem cells have been isolated from human lung cancer and cancer cell lines. ... Cell Proliferation. Glycoproteins / analysis. Humans. Lung Neoplasms / pathology*. Mice. Mice, Inbred BALB C. Neoplastic Stem ... most A549 and H446 cells may not be stem cells, but they acquired stem cell characteristics when they were alone. Therefore, ...http://www.biomedsearch.com/nih/More-than-45-A549-H446/19287999.html
'Double hit' makes the...
Neoplastic Stem Cells / drug effects*. Chemical. Reg. No./Substance: 50-99-7/Glucose; 657-24-9/Metformin ... is the use of such dual therapy to target cancer stem cells. Metformin has been shown to selectively kill cancer stem cells and ... the chemotherapy-resistant subpopulation of cancer stem cells.8,9 Cancer stem cells greatly depend on aerobic glycolysis to ... but is adequate to maintain viable cells in most of the cancer cells. Indeed, metformin blocks cell growth but can also induce ...http://www.biomedsearch.com/nih/Double-hit-makes-difference/22874594.html
Blood and Lymph Unit 3 Flashcards by Kristen Stahl | Brainscape
... clonal population of neoplastic hematopoietic stem cells takes over marrow. cannot make normal blood cells, falling peripheral ... derive from B cells. Non-Hodgkin Lymphoma: any malignancy derived from mature B, T, NK cells. Majority are B cells. Plasma Cell ... malignant cells=small minority (0.1-2% of total cell pop). -RS cells. -immunophenotype: tumor cells express CD30 and CD15 ... b. mantle cell lymphoma- mantle cell. c. follicular lymphoma- germinal B cell. d. hodgkin lymphoma- germinal B cell. e. burkitt ...https://www.brainscape.com/flashcards/blood-and-lymph-unit-3-4806757/packs/6999439
Stem cell biology in health and disease - کتابخانه الکترونیک و دیجیتال - آذرسا
Stem cell biology in health and disease , کتابخانه الکترونیک و دیجیتال - آذرسا ... Embryonic stem cells -- Cancer stem cells Bibliographies/Indexes : Bibliography Subject : Stem Cells Neoplastic Stem Cells Stem ... Stem cell biology in health and disease , ... Stem cell biology in health and disease Publication Statement : ...http://azarsa.tbzmed.ac.ir/site/catalogue/7280
POSTN induces osteoblastic and myogenic differentiation | Open-i
Cell Adhesion Molecules/genetics*. *Multipotent Stem Cells/cytology/metabolism*. *Neoplastic Stem Cells/cytology/metabolism* ... Here we demonstrate that POSTN promotes a stem cell-like trait and a mesenchymal phenotype in human mammary epithelial cells ... Here we demonstrate that POSTN promotes a stem cell-like trait and a mesenchymal phenotype in human mammary epithelial cells ... Periostin contributes to the acquisition of multipotent stem cell-like properties in human mammary epithelial cells and breast ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3756944_pone.0072962.g004&req=4
MiR-100 impairs CSC properties by down-regulating Plk1A | Open-i
By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy. ... Cell Cycle Proteins/genetics/metabolism. *Cell Line, Tumor. *Female. *Gene Expression Regulation, Neoplastic ... Tumor formation and relapse are sustained by a cell subset of Breast Cancer Stem Cells (BrCSCs). Here we show that miR-100 ... Tumor formation and relapse are sustained by a cell subset of Breast Cancer Stem Cells (BrCSCs). Here we show that miR-100 ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC4385854_oncotarget-06-2315-g005&req=4
Thrombospondin-1 | SpringerLink
Divergent modulation of normal and neoplastic stem cells by thrombospondin-1 and CD47 signaling. Int J Biochem Cell Biol. 2016 ... Cell Mol Life Sci. 2008;65:672-86.PubMedPubMedCentralCrossRefGoogle Scholar ... Visavadiya NP, Li Y, Wang S. High glucose upregulates upstream stimulatory factor 2 in human renal proximal tubular cells ...https://link.springer.com/referenceworkentry/10.1007/978-3-319-67199-4_637
Extracellular Vesicles: A New Prospective in Crosstalk between Microenvironment and Stem Cells in Hematological Malignancies
... and clinical studies in all areas of stem cell biology and applications. The journal will consider basic, translational, and ... Stem Cells International is a peer-reviewed, Open Access journal that publishes original research articles, review articles, ... Cancer stem cells (CSCs), neoplastic cells, hematopoietic stem cells (HSCs), and mesenchymal stromal/stem cells (MSCs) are all ... Y. Kfoury and D. T. Scadden, "Mesenchymal cell contributions to the stem cell niche," Cell Stem Cell, vol. 16, no. 3, pp. 239- ...https://www.hindawi.com/journals/sci/2018/9863194/
adult optic nerve glioma 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Neoplastic Stem Cells / pathology. Optic Nerve Glioma / pathology. *[MeSH-minor] Adult Stem Cells / pathology. Biomarkers / ... Lasky JL 3rd, Choe M, Nakano I: Cancer stem cells in pediatric brain tumors. Curr Stem Cell Res Ther; 2009 Dec;4(4):298-305. ... The adult population presented more cases of basal cell carcinomas (18 cases), squamous cell carciomas (12 cases), meningiomas ... Cell Differentiation. Chemotherapy, Adjuvant. Child. Humans. Surgical Procedures, Operative. *Genetic Alliance. consumer health ...http://www.bmlsearch.com/?kwr=adult+optic+nerve+glioma+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
embryonal carcinoma of testis diagnosis drug therapy 2000:2010[pubdate] *count=100 - BioMedLib™ search engine
Neoplasms, Germ Cell and Embryonal / etiology. Neoplasms, Germ Cell and Embryonal / genetics. Neoplastic Stem Cells / ... Embryonal Carcinoma Stem Cells. Epigenesis, Genetic / physiology. Humans. Male. Models, Biological. Stem Cells / physiology ... Such atypical cells appear in the tubules adjacent to the germ cell tumors, in some few cases (6%) also in the contra lateral ... Neoplastic Cells, Circulating. Vascular Neoplasms / diagnosis. Vascular Neoplasms / secondary. Vascular Neoplasms / surgery. ...http://www.bmlsearch.com/?kwr=embryonal+carcinoma+of+testis+diagnosis+drug+therapy+2000:2010%5Bpubdate%5D&cxts=100&stmp=b1
Kenneth Pienta - Research Output - Johns Hopkins University
Correction: The marrow niche controls the cancer stem cell phenotype of disseminated prostate cancer [Oncotarget., 7, (2016) ( ...https://jhu.pure.elsevier.com/en/persons/kenneth-pienta/publications/?type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fcontributiontojournal%2Fcomment
Johns Hopkins University - Research Output - Johns Hopkins University
Neoplastic Stem Cells Epigenomics Musculoskeletal MRI structured evaluation: How to practically fill the reporting checklist. ... Biomarkers in neoplastic neuropathology. Rodriguez, F. & Ho, C. Y. Jan 1 2016 Springer International Publishing. 98 p.. ... An introduction to neuroscientific methods: Single-cell recordings. Stuphorn, V. & Chen, X. Jan 1 2015 Springer New York. 25 p. ...https://jhu.pure.elsevier.com/en/organisations/johns-hopkins-university-3/publications/?type=%2Fdk%2Fatira%2Fpure%2Fresearchoutput%2Fresearchoutputtypes%2Fbookanthology%2Fbook
John J Laterra - Research Output - Johns Hopkins University
Neoplastic Stem Cells Profiling the dynamics of a human phosphorylome reveals new components in HGF/c-Met signaling.. Woodard, ... Cancer stem cells: Distinct entities or dynamically regulated phenotypes?. Li, Y. & Laterra, J. Feb 1 2012 In : Cancer Research ... Regulation of glioblastoma stem cells by retinoic acid: Role for Notch pathway inhibition. Ying, M., Wang, S., Sang, Y., Sun, P ... Lipid metabolism enzyme ACSVL3 supports glioblastoma stem cell maintenance and tumorigenicity. Sun, P., Xia, S., Lal, B., Shi, ...https://jhu.pure.elsevier.com/en/persons/john-j-laterra/publications/
Frontiers | Commentary: "Prom1 Function in Development, Intestinal Inflammation, and Intestinal Tumorigenesis" | Oncology
Besides progenitor cells, its expression is widespread throughout terminally differentiated cells as those found in glandular ... is related to its use as a stem and cancer stem cell marker (1). ... marks intestinal stem cells that are susceptible to neoplastic ... is related to its use as a stem and cancer stem cell marker (1). Besides progenitor cells, its expression is widespread ... Lardon J, Corbeil D, Huttner WB, Ling Z, Bouwens L. Stem cell marker prominin-1/AC133 is expressed in duct cells of the adult ...https://www.frontiersin.org/articles/10.3389/fonc.2015.00091/full
Cancer Stem Cell News: More about presentations at AACR10
Role of telomerase in normal and neoplastic stem cells [Presentation Abstract].. Another poster about the telomerase inhibitor ... Cancer Stem Cell News A blog of news items related to cancer stem cells, with an emphasis on recent research and articles that ... The editor is a member of the Board of Directors of the Cancer Stem Cell Consortium (CSCC), which is based in Ottawa, Canada.. ... Stem cells in cancer: do they matter? (Video of lecture by John Dick, 2014) ...http://cancerstemcellnews.blogspot.com/2010/05/more-about-presentations-at-aacr10.html
5th International Congress on Myeloproliferative Diseases and Myelodysplastic Syndromes - 5. - 7. 11. 2009, New York Marriott...
11:30 am Keynote Address: Normal and neoplastic stem cells Speaker invited. 12:15 pm Discussion / Questions. 12:30 pm Lunch. ... 2:30 pm Migration of hematopoetic stem cells and niche abnormalities Speaker invited. 3:00 pm Novel therapies and assessing ...https://www.linkos.cz/lekar-a-multidisciplinarni-tym/celozivotni-vzdelavani/kongresy/kongresovy-kalendar/5th-international-congress-on-myeloproliferative-diseases-and-myelodysplastic-sy/
Autologous Stem/Stromal Cells in Neurological Disorders and Disease - Full Text View - ClinicalTrials.gov
Use Of Autologous Stem Cell Use In Neurological Non-neoplastic Disorders And Disease. ... Autologous Stem/Stromal Cells in Neurological Disorders and Disease (NDD). The safety and scientific validity of this study is ... The study deals with evaluation of safety and efficacy of use of stem/stromal cell isolates from autologous microvasculature in ... that there are minimal or no significant risk of harm to general health or conditions for collection of autologous stem cell ...https://www.clinicaltrials.gov/ct2/show/NCT03297177?recrs=a&cond=Huntington+Disease&rank=27
Evaluation of the effect of the CXCR6 ligand CXCL16 on | Open-i
Evaluation of the effect of the CXCR6 ligand CXCL16 on melanoma cell line growth.Twenty thousand cells were seeded overnight in ... neoplastic growth and its origin from normal tissue cells.We defined CXCR6 as a new biomarker for tissue-specific stem cell ... neoplastic growth and its origin from normal tissue cells.We defined CXCR6 as a new biomarker for tissue-specific stem cell ... In addition, ABCG2+ cells produced tumors that had a 2-fold greater mass than tumors produced by unsorted cells or ABCG2- cells ...https://openi.nlm.nih.gov/detailedresult.php?img=PMC3008677_pone.0015183.g011&req=4