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*  Nuclear Factor-Kappa B, Cancer, and Apoptosis - Bours Vincent
NF-kappa B activation is required for the onset of apoptosis. Therefore, it is likely that the NF-kappa B antiapoptotic role in ... Constitutive NF-kappa B activity in B lymphocytes as well as in Hodgkin's disease and breast cancer cells protects these cells ... en] The role of nuclear factor (NF)-kappa B in the regulation of apoptosis in normal and cancer cells has been extensively ... It has also been reported that NF-kappa B activation by tumor necrosis factor (TNF)-alpha, chemotherapeutic drugs, or ionizing ...
  http://orbi.ulg.ac.be/handle/2268/18485
*  LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth | Development
The transcription factor nuclear factor-kappa B (NF-κB) plays an essential role in epidermal appendage induction and ... In addition to corroborating established NF-κB functions, these analyses uncovered novel NF-κB target genes with potential ... NF-κB signaling is known to modulate activity of WNT and SHH signaling at early stages of hair follicle development, but these ... To identify additional NF-κB target genes we developed a novel method to isolate and transcriptionally profile primary hair ...
  http://dev.biologists.org/content/early/2016/03/03/dev.130898
*  tyrosine hydroxylase has a key role in the physiology of adrenergic neurons. - NF-κB signaling in inflammation and cancer
Today's study seeks to research the role of cathepsin L in glutamate receptor-induced transcription factor nuclear factor-kappa ... B (NF-B) activation and excitotoxicity in rats striatal neurons. degradation and phosphorylation, adjustments in the degrees of ...
  http://healthcarecoremeasures.com/tag/tyrosine-hydroxylase-has-a-key-role-in-the-physiology-of-adrenergic-neurons/
*  Abstract 590: Abrogation of Nuclear Factor-Kappa B Activation in the Heart Alleviates Post-Infarction LV Remodeling |...
significantly (p , 0.05) increased (~2-fold) NF-κB DNA binding activity and mRNA levels of the NF-κB-responsive cytokines tumor ... As NF-κB can signal to either survival or apoptotic pathways, however, whether such activation confers cardioprotective or ... Conclusion: Persistent NF-κB activation imparts detrimental effects in post-infarction HF and worsens LV remodeling, related, ... Abstract 590: Abrogation of Nuclear Factor-Kappa B Activation in the Heart Alleviates Post-Infarction LV Remodeling. Tariq ...
  http://circ.ahajournals.org/content/114/Suppl_18/II_95.3
*  Rabbit polyclonal to Tyrosine Hydroxylase.Tyrosine hydroxylase (EC 1.14.16.2) is involved in the conversion of phenylalanine to...
Today's study seeks to research the role of cathepsin L in glutamate receptor-induced transcription factor nuclear factor-kappa ... B (NF-B) activation and excitotoxicity in rats striatal neurons. degradation and phosphorylation, adjustments in the degrees of ...
  http://healthcarecoremeasures.com/tag/rabbit-polyclonal-to-tyrosine-hydroxylase-tyrosine-hydroxylase-ec-1-14-16-2-is-involved-in-the-conversion-of-phenylalanine-to-dopamine-as-the-rate-limiting-enzyme-in-the-synthesis-of-catecholamines/
*  What does i-kappa b proteins mean?
Meaning of i-kappa b proteins. What does i-kappa b proteins mean? Information and translations of i-kappa b proteins in the ... Definition of i-kappa b proteins in the Definitions.net dictionary. ... In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and ... What does i-kappa b proteins mean?. Definitions for i-kappa b proteins. Here are all the possible meanings and translations of ...
  http://www.definitions.net/definition/i-kappa%20b%20proteins
*  NF-kappa-B-activating protein (Q8N5F7) | InterPro | EMBL-EBI
InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.
  http://www.ebi.ac.uk/interpro/protein/Q8N5F7
*  Nuclear factor NF-kappa-B p105 subunit (P19838) | InterPro | EMBL-EBI
NF-kappa-B/Dorsal (IPR000451)*Nuclear factor NF-kappa-B, p105 subunit (IPR030503) ...
  http://www.ebi.ac.uk/interpro/protein/P19838
*  Nfkbia - NF-kappa-B inhibitor alpha - Rattus norvegicus (Rat) - Nfkbia gene & protein
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their ... an I kappa B that inhibits NF-kappa B, RelB-p50, and c-Rel-p50) and PHF, a novel kappa B site-binding complex.". Tewari M., ... NF-kappa-B inhibitor alphaAdd BLAST. 314. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical ... Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their ...
  http://www.uniprot.org/uniprot/Q63746
*  Nfkbie - NF-kappa-B inhibitor epsilon - Mus musculus (Mouse) - Nfkbie gene & protein
Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes (By similarity). ... Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. ... Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c- ... Interacts with RELA, REL, NFKB1 nuclear factor NF-kappa-B p50 subunit and NFKB2 nuclear factor NF-kappa-B p52 subunit.By ...
  https://www.uniprot.org/uniprot/O54910
*  Nfkbil1 - NF-kappa-B inhibitor-like protein 1 - Mus musculus (Mouse) - Nfkbil1 gene & protein
Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous ... NF-kappa-B inhibitor-like protein 1Add BLAST. 381. Amino acid modifications. Feature key. Position(s). DescriptionActions. ... sp,O88995,IKBL1_MOUSE NF-kappa-B inhibitor-like protein 1 OS=Mus musculus OX=10090 GN=Nfkbil1 PE=2 SV=1 ... Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous ...
  https://www.uniprot.org/uniprot/O88995
*  Influence of Block of NF-Kappa B Signaling Pathway on Oxidative Stress in the Liver Homogenates
... Paulina Kleniewska,1 ... The aim of the present study was to assess whether BAY 11-7082, a nuclear factor-kappaB (NF-κB) inhibitor, influences the level ... control). ET-1 administration slightly downregulated gene expression of p65 of NF-κB but potently and in a dose-dependent way ... of reactive oxygen species (ROS), tumor necrosis factor alpha (TNF-α), and NF-κB related signaling pathways in the liver. The ...
  https://www.hindawi.com/journals/omcl/2013/308358/abs/
*  NF-kappa B genes have a major role in Inflammatory Breast Cancer
Jr Selective activation of NF-kappa B subunits in human breast cancer: potential roles for NF-kappa B2/p52 and for Bcl-3. ... NF-kappa B genes have a major role in Inflammatory Breast Cancer. Florence Lerebours,. 1,2 Sophie Vacher,1,2 Catherine Andrieu, ... NF-kappa B activation in human breast cancer specimens and its role in cell proliferation and apoptosis. Proc Natl Acad Sci USA ... The 35 upregulated genes included NF-κB genes (NFKB1, RELA, IKBKG, NFKBIB, NFKB2, REL, CHUK) and NF-κB-regulated genes involved ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2267801/?lang=en
*  NKIRAS1 - NF-kappa-B inhibitor-interacting Ras-like protein 1 - Homo sapiens (Human) - NKIRAS1 gene & protein
May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear ... Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B ... NF-kappa-B inhibitor-interacting Ra.... NF-kappa-B inhibitor-interacting Ras-like protein 1 (NFKB inhibitor interacting Ras- ... Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B ...
  https://www.uniprot.org/uniprot/Q9NYS0
*  NF-kappa-B-activating protein - Wikipedia
NF-kappa-B-activating protein is a protein that in humans is encoded by the NKAP gene. GRCh38: Ensembl release 89: ... "Entrez Gene: NKAP NF-kappaB activating protein". Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial ... Zhande R, Karsan A (2007). "Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF- ... 2004). "Inverse correlation between p16INK4A expression and NF-kappaB activation in melanoma progression". Hum. Pathol. 35 (8 ...
  https://en.wikipedia.org/wiki/NF-kappa-B-activating_protein
*  Inhibition of NF-kappa B, a key inflammatory protein, reduced radiation toxicity in zebrafish
Rodeck, the key is to downmodulate the NF-kappa B activity, rather than ablating it completely, as excessive NF-kappa B ... Inhibition of NF-kappa B, a key inflammatory protein, reduced radiation toxicity in zebrafish. September 1, 2009 Directly ... Reporting in Molecular Cancer Therapeutics, the researchers found that inhibitors of NF-kappa B not only protected against ... "We started with the premise that NF-kappa B activity might be helpful in protecting cells against the harmful effects of ...
  https://medicalxpress.com/news/2009-09-inhibition-nf-kappa-key-inflammatory-protein.html
*  The effect of the NF-kappa B inhibitors curcumin and lactacystin on myogenic differentiation of rhabdomyosarcoma cells.
In addition, we inhibited NF-κB activity in these cells and analyzed the effects on myogenic differentiation. We show that ... However, after treatment of the cells with two different small-molecule NF-κB-inhibiting compounds, the IKK inhibitor curcumin ... Thus, here, we tested whether the ubiquitous transcription factor NF-κB, which regulates myogenic differentiation and is also a ... For this purpose, we analyzed NF-κB activity (classical pathway) in myoblasts with different differentiation potential, ...
  http://www.biomedsearch.com/nih/effect-NF-kappa-B-inhibitors/22469857.html
*  NF-kappa B-inducible BCL-3 expression is an autoregulatory loop controlling nuclear p50/NF-kappa B1 residence.
In the NF-kappa B-I kappa B autoregulatory loop, activated (nuclear) Rel A.NF-kappa B1 induces the resynthesis of I kappa B ... presence of an NF-kappa B-BCL-3 autoregulatory loop important in terminating NF-kappa B1 action and that individual NF-kappa B ... NF-kappa B-inducible BCL-3 expression is an autoregulatory loop controlling nuclear p50/NF-kappa B1 residence.. Brasier A.R., ... Down-regulation of BCL-3 induction results in prolonged, enhanced NF-kappa B1 binding and increased NF-kappa B-dependent ...
  https://www.uniprot.org/citations/11387332
*  NFKB1 / NF-Kappa-B Antibody (N-Terminus) for WB/Western, IP, ELISA LS-C9278
NF-Kappa-B antibody LS-C9278 is an unconjugated rabbit polyclonal antibody to human NF-Kappa-B (NFKB1). Validated for ELISA, IP ... About NFKB1 / NF-Kappa-B. NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint ... NF-Kappa-B antibody LS-C9278 is an unconjugated rabbit polyclonal antibody to human NF-Kappa-B (NFKB1). Validated for ELISA, IP ... NF-Kappa-B antibody LS-C9278 is an unconjugated rabbit polyclonal antibody to human NF-Kappa-B (NFKB1). Validated for ELISA, IP ...
  https://www.lsbio.com/antibodies/anti-nfkb1-antibody-nf-kappa-b-antibody-n-terminus-elisa-ip-wb-western-ls-c9278/10019
*  Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta (I-Kappa B Kinase Beta or Nuclear Factor NF-Kappa-B Inhibitor Kinase...
I-Kappa B Kinase Beta or Nuclear Factor NF-Kappa-B Inhibitor Kinase Beta or IKBKB or I-Kappa-B Kinase 2 or IKK2 or NFKBIKB or ... Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta ( ... NF-kappa-B activation and phosphorylates inhibitors of NF-kappa ... The report reviews Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta (I-Kappa B Kinase Beta or Nuclear Factor NF-Kappa-B ... Product: Inhibitor of Nuclear Factor Kappa-B Kinase Subunit Beta (I-Kappa B Kinase Beta or Nuclear Factor NF-Kappa-B Inhibitor ...
  https://www.researchandmarkets.com/reports/3788902/inhibitor-of-nuclear-factor-kappa-b-kinase
*  TL1-A can engage death receptor-3 and activate NF-kappa B in endothelial cells | BMC Nephrology | Full Text
TL1A induces NF-κB activation in EC in renal and cardiac tissue from wild type but not DR3 knock-out mice. TL1A and DR3 ... these EC also respond to its ligand TL1A by activating NF-κB. Very low levels of DR3 can be detected on the cell surface of ... activate NF-κB in vascular endothelial cells, and can be an important regulator of renal interstitial vascular injury. ... the interstitial EC positive for DR3 showed strong signal for NF-κBp65 indicative of NF-κB activation (Figure 1D-F). NF-κB ...
  https://bmcnephrol.biomedcentral.com/articles/10.1186/1471-2369-15-178
*  NF-kappa B | Colorado PROFILES
The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA. ... "NF-kappa B" by people in this website by year, and whether "NF-kappa B" was a major or minor topic of these publications. ... "NF-kappa B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject ... Below are the most recent publications written about "NF-kappa B" by people in Profiles. ...
  https://profiles.ucdenver.edu/display/202828
*  NF-kappa-B essential modulator
Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from ... the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B ... NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 11 ... This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting ...
  https://pharos.nih.gov/idg/targets/IKBKG
*  NF-kappa-B inhibitor beta
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and ... IKK-NF-kappaB cascade ( B cell receptor signaling ) 8 IKK-NF-kappaB cascade ( CD4 T cell receptor signaling (NF-kB cascade) ) 8 ... Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after ... NF-kB signaling ( Toll-like receptor signaling pathway (trough NF-kappaB) ) 12 ...
  https://pharos.nih.gov/idg/targets/Q15653