Mucin-1 - Wikipedia
Mucin-1 (MUC-1) is a heterodimer transmembrane protein of the mucin family encoded in humans by the MUC1 gene. It is cleaved ... In addition to the membranous isoform, an alternatively spliced mucin-1 is secreted extracellularly. MUC-1 in cancer is ... mucin-1 subunit alpha (MUC1-NT; MUC1-alpha) and mucin-1 subunit beta (MUC-CT; MUC1-beta). These subunits differ in size due to ... isolated mucin preparations, and tumor cells. Developed MUC-1 monoclonal antibodies are used in diagnosis of cancer, and ...
Development and Validation of a Mass Spectrometry-Based Assay for the Molecular Diagnosis of Mucin-1 Kidney Disease
Mucin-1 kidney disease, previously described as medullary cystic kidney disease type 1 (MCKD1, OMIM 174000), is an autosomal ... Development and Validation of a Mass Spectrometry-Based Assay for the Molecular Diagnosis of Mucin-1 Kidney Disease. Author(s) ... Because of variable age of disease onset and often subtle signs and symptoms, clinical diagnosis of mucin-1 kidney disease and ... "Development and Validation of a Mass Spectrometry-Based Assay for the Molecular Diagnosis of Mucin-1 Kidney Disease." The ...
Mucin-1 Monoclonal Antibody [VU12E1] - ImmuQuest
The Role of the Cell Surface Mucin MUC1 as a Barrier to Infection and Regulator of Inflammation.Front Cell Infect Microbiol 24; ... Almasmoum H. The Roles of Transmembrane Mucins Located on Chromosome 7q22.1 in Colorectal Cancer.Cancer Manag Res. 13:3271-3280 ... Cancer Cell Int 21(1):200 (2021).. View Source. Beckwith D M et al. Crosstalk between MUC1 and VEGF in angiogenesis and ... Optimal antibody dilution should be determined by titration, however as a guideline use at WB 0.3µg/ml, ICC/IF 1:100, Flow Cyt ...
Cosrx Advanced Snail Mucin Power Sheet Mask 1 Sheet | Kiokii and...
Human muc 1 mucin gene expression in the fetal pancreas - Fingerprint - Research Nebraska
Studying Circulating Tumor Cells at the Protein Level
Mucin 1. Colon, lung, breast, ovarian, pancreatic, prostate, kidney, stomach, head and neck. [37-40]. ... Charles Ming Lok Chan1Thomas Chi Chuen Au1Anthony Tak Cheung Chan1Brigette Buig Yue Ma1Nancy Bo Yin Tsui2Simon Siu Man Ng3Edwin ... 1Department of Clinical Oncology, State Key Laboratory in Oncology in South China, Sir Y K Pao Centre for Cancer, Hong Kong ... Table 1. Protein markers commonly used for circulating tumor cells investigations. Target protein. Examples of cell/tissue ...
Length of the antibody heavy chain complementarity determining region 3 as a specificity-determining factor
MedlinePlus: Genes: M
CA 15-3: uses and limitation as a biomarker for breast cancer
CA 15-3 which detects soluble forms of MUC-1 protein is the most widely used serum marker in patients with breast cancer. Its ... 1 Department of Pathology and Laboratory Medicine, St Vincents University Hospital, Dublin 4, Ireland. [email protected] ... CA 15-3 which detects soluble forms of MUC-1 protein is the most widely used serum marker in patients with breast cancer. Its ... Mucin-1 / blood * Mucin-1 / chemistry * Mucin-1 / metabolism* * Neoplasm Metastasis * Postoperative Period ...
Recent evolution of the salivary mucin MUC7 | Scientific Reports
PTS-repeats are a hallmark of the mucin group of proteins6. Mucins are highly glycosylated proteins that serve a variety of ... It should be noted here that most other mucins, including MUC1, MUC4, and MUC6, have intact PTS-repeats in mouse33,34,35, ... In fact, mucins, as a functional group, are defined by the presence of PTS-rich repeats6, where T and S clusters provide ... Desseyn, J.-L. & Mucin C. Y. S. domains are ancient and highly conserved modules that evolved in concert. Mol. Phylogenet. Evol ...
Mucin-Like Domain regarding Mucosal Addressin Mobile or portable Bond Molecule-1 Facilitates Integrin α4β7-Mediated Mobile |...
Mucin-Like Domain regarding Mucosal Addressin Mobile or portable Bond Molecule-1 Facilitates Integrin α4β7-Mediated Mobile. ... Increased basic lcd sRAGE (Hours per-one firewood rise, 1.Fifty three; 95% CI, 1.16-2.03; r Equates to Zero.003) and an ... lcd sRAGE stage every product of your energy elevated the chance of dying from day Three months by selleck kinase inhibitor 1% ...
Chapter - Mucin MUC7 | Bentham Science
Mucin MUC7, Mucins - Potential Regulators of Cell Functions Volume Title: Gel-Forming and Soluble Mucins (2013) 1: 398. https ... Mucins - Potential Regulators of Cell Functions Volume Title: Gel-Forming and Soluble Mucins ... Mucin MUC7. Author(s): Joseph Z. Zaretsky and *Department of Cell Research and Immunology George S. Wise Faculty of Life ... The MUC7 gene belongs to a group of genes encoding soluble mucin glycoproteins. This chapter describes the structure of the ...
Effect Of Multipurpose Contact Lens Care Solutions On Membrane-associated Mucins Expressions In The Rat Cornea | IOVS | ARVO...
Membrane-associated mucins are one of the major components of the ocular surface that play a vital role in the maintenance of ... Membrane-associated mucins (Muc 1 and Muc 16) expressions were subsequently analyzed by Western blot. Winstar Rats were also ... Purpose: : To evaluate the effect of multipurpose contact lens care solutions (MPSs) on membrane-associated mucins (Muc 1 & 16 ... Results: : Western blot results showed that MPSs containing boric acid down-regulate membrane-associated mucins in the cornea ...
AVHANDLINGAR.SE: Studies on o-glycosylation of mucin-type proteins and their binding to antibodies, bacterial toxins and viral...
Avhandling: Studies on o-glycosylation of mucin-type proteins and their binding to antibodies, bacterial toxins and viral ... The multivalent mucins could adsorb chain type - sp ecific anti - A antibodies, which indicate a prospective use of the mucins ... The mucin - type protein was used as a probe to analyze the O - glycosylation capacity of the se cell lines, which today are ... Studies on o-glycosylation of mucin-type proteins and their binding to antibodies, bacterial toxins and viral receptors Detta ...
LOC105374301 | 遺伝子情報 | J-GLOBAL 科学技術総合リンクセンター
IWR-1-endo | WNT Pathway Inhibitor | STEMCELL Technologies
IWR-1 endo potently inhibits WNT signaling and WNT-induced accumulation of β-catenin, through stabilization of the destruction ... for mucin-1, 93% for surfactant protein B, and 89% for the epithelial marker CD54. Additionally, exposing induced ... IWR-1-endo potently inhibits WNT signaling by blocking a cell-based WNT/β-catenin pathway reporter response with an IC₅₀ value ... We found that of induced AET1 cells, more than 90% were positive for type I markers, T1α, and caveolin-1. Acellular lung ...
Intrinsic Sleep Disorders - Ontology Report - Rat Genome Database
mucin 1, cell surface associated. ISO. protein:increased expression:plasma. RGD. PMID:19336590. RGD:5131166. NCBI chrNW_ ... PPARG coactivator 1 alpha. ISO. DNA:SNP:cds:p.G482S (rs8192678) (human). RGD. PMID:22392034. RGD:6484261. NCBI chrNW_004955480: ... cysteinyl leukotriene receptor 1. ISO. protein:increased expression:tonsil, T cell. RGD. PMID:18490405. RGD:4888517. NCBI chrNW ... Meis homeobox 1. ISO. CTD Direct Evidence: marker/mechanism. CTD. PMID:17637780 PMID:28604731. NCBI chrNW_004955424:18,060,499 ...
Medullary Cystic Disease: Practice Essentials, Background, Pathophysiology
9] The abnormal mucin 1 protein accumulates intracellularly in the distal nephron segments. How this accumulation of protein ... MCKD type 1 has a median onset of ESRD at age 62 years and is caused by defects in the MUC1 gene that encodes mucin 1. [9] ... The median age of onset of ESRD is 13 years in juvenile NPH, 1-3 years in infantile NPH, and 19 years in adolescent NPH. [18] ... Median onset of ESRD is age 62 years for MCKD type 1 and age 32 years for MCKD type 2. [9, 10, 11, 12] ...
Human TIM-1/KIM-1/HAVCR Alexa Fluor® 405-conjugated Antibody FAB1750V-100UG: R&D Systems
View Human TIM-1/KIM-1/HAVCR Alexa Fluor® 405-conjugated Antibody (FAB1750V-100UG) datasheet. ... The ECD contains oneV-type Ig-like domain and a mucin region characterized by multiple PTTTTL motifs. The mucin region ... T-cell immunoglobulin and mucin domain-containing protein 1; TIM1; TIM-1; TIM-1TIM; TIM1TIMD-1; TIMD1T-cell membrane protein 1 ... HAVCRT cell immunoglobin domain and mucin domain protein 1; hepatitis A virus cellular receptor 1; Kidney injury molecule 1; ...
Medical Science Monitor | Combined Blockade of T Cell Immunoglobulin and Mucin Domain 3 and Carcinoembryonic Antigen-Related...
T cell immunoglobulin and mucin domain 3 (Tim-3) is a key checkpoint receptor responsible for exhaustion and dysfunction of T ... Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) has been recently identified as a heterophilic ligand for ... T cell immunoglobulin and mucin domain 3 (Tim-3) is a key checkpoint receptor responsible for exhaustion and dysfunction of T ... Combined Blockade of T Cell Immunoglobulin and Mucin Domain 3 and Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 ...
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IJMS | Special Issue : Signalling Molecules and Signal Transduction in Cells
Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors: Correlation to Mucin-1 ... Correlation analysis revealed an overall positive correlation between pEGFR Y845 and mucin 1 (MUC1). Further subgroup analysis ... Endothelial mPGES-1 exacerbates KA-induced neuronal damage in in vivo experiments. In in vitro experiments, mPGES-1 produces ... In contrast, silencing of Cas-1, Scap and S2P from SREBP pathway had no affect on Cry11Aa toxicity in A. aegypti larvae. ...
'Phenomenal': Amazon's No. 1 bestselling joggers are down to $13 (that's nearly 50%...
muco-, muc-, muci-, mucin- + - Word Information
... mucin in the blood.. 2. The presence of mucin in blood, a condition that may occur in metastatic malignancies of the ... muco-, muc-, muci-, mucin- + (Latin: mucus, mucous, or mucosa; a viscid, slippery, slime secretion of the mucous membranes; ... Resembling mucin or mucus present in saliva and bile, in salivary glands, and in the skin, connective tissues, tendon, and ... Capable of bringing about the hydrolysis (splitting of a compound into fragments by the addition of water) of mucin, as by a ...
Frontiers | Resolving Viral-Induced Secondary Bacterial Infection in COPD: A Concise Review
Neutrophil elastase induces mucin production by ligand-dependent epidermal growth factor receptor activation. Am J Physiol Lung ... Neutrophil elastase induces MUC5AC mucin production in human airway epithelial cells via a cascade involving protein kinase C, ... Neutrophils can also increase mucin production by activating epidermal growth factor receptor (EGFR) signaling (41), which ... Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells. Proc Natl Acad Sci USA. (2005) 102: ...
Keratins - Keratin Summary Report | CureHunter
Profile, School of Pharmacy | University of Otago
2019 Cilia, Mucus and Mucociliary Interactions Conference GRC
Cell Biology of Cilia, Flow and Mucin Components Discussion Leaders: Burton Dickey (University of Texas MD Anderson Cancer ... Protein Assembly and Structure: Translating Messages to Build Mucins and Cilia Discussion Leaders: Eszter Vladar (University of ... Bcl-2 Modifying Factor (Bmf) Reduces Goblet Cell Metaplasia by Enhancing Mucin Degradation ... The C-Terminal Dimerisation Domain of Mucin MUC5B: Structure, Stability and Interactions ...
What is dry eye syndrome? | 1-800-GET-LENS
Mucin. Mucin is a mucous-like substance that is produced by cells in the conjunctiva and outer surface of the eye. It helps ... 1995-2023 1-800-GET-LENS. All Rights Reserved. Terms & Conditions of Use , Privacy Policy , Site Map ... but at least one survey suggests that approximately 20 percent of people in the United States suffer from dry eye syndrome.1 ...
Dissertations.se: BIOLOGISK KEMI
Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Glycopeptides; mucins; mucin type-O- ... Development and Evaluation of Tools to Explore Posttranslational HexNAc-Tyrosine and Mucin-Type O-Glycosylation. Author : ... Showing result 1 - 5 of 44 swedish dissertations containing the words biologisk kemi. ...