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*  A New, Genetic Model for Schizophrenia - Scientific American
A New, Genetic Model for Schizophrenia. A new study points to rare gene duplications and deletions that are believed to play a ... Until now, most scientists believed that it was likely that a cluster of relatively common genetic mutations was to blame.. ' ... Their probes turned up a few possible genetic suspects, but the findings were contradicted by those from other studies. In ... Sebat acknowledges that the data presented is merely consistent with the rare mutation gene model and not direct proof of it. ' ...
  https://www.scientificamerican.com/article/new-genetic-model-schi/
*  Mouse genetic model for spongiform brain diseases
Some mice with a genetic mutation for mahogany-colored coats also develop spongiform degeneration of brain tissue, similar to ... Because of this oddity, the mice could be valuable animal models for human disorders, such as Parkinson's and Alzheimer's ... As an animal model, the mahoganoid mutant mice probably will not be useful to study spongiform encephalopathies like mad cow ... Cornell geneticist Teresa Gunn displays a mahoganoid mutant mouse, a possible animal model for brain disease in humans. ...
  http://www.innovations-report.com/html/reports/life-sciences/report-16142.html
*  Development of Porcine Genetic Models of Atherosclerosis | SBIR.gov
The ideal pig model would be of manageable size and manifest both metabolic syndrome and atherosclerosis at an early age. Like ... In this Phase 1 STTR we propose to generate a pig model of metabolic syndrome and rapid atherosclerosis by knocking out the low ... Indeed, a consensus report concerning FDA approval of the stents recommends the use of the pig model to assess these devices. ... However, a marked deficiency in current pig models is that they do not present with metabolic syndrome and significant ...
  https://www.sbir.gov/sbirsearch/detail/370162
*  ARL-TR-6354 - Modeling Genetic Regulatory Networks Using First-Order Probabilistic Logic | U.S. Army Research Laboratory
There is a need to model biological systems to aid in medication and drug delivery. Genetic Regulatory Networks (GRNs) ... GRNs can be modeled using statistical and logical techniques, more precisely using Bayesian networks. Bayesian networks are ... a learning algorithm was implemented to determine the structure and the parameters of Bayesian networks that model GRNs from ... Modeling Genetic Regulatory Networks Using First-Order Probabilistic Logic. Report No.. ARL-TR-6354. ...
  http://www.arl.army.mil/www/?technical_report=6697
*  Sodium and Water Homeostasis - Comparative, Evolutionary and Genetic Models | Kelly Anne Hyndman | Springer
Comparative, Evolutionary and Genetic Models. Editors: Hyndman, Kelly Anne, Pannabecker, Thomas L. (Eds.) ... Greater integration of comparative, evolutionary and genetic animal models in basic science and medical science will improve ... Non-traditional Models: The Molecular Physiology of Sodium and Water Transport in Mosquito Malpighian Tubules ... Non-traditional Models: The Giraffe Kidney from a Comparative and Evolutionary Biology Perspective ...
  https://www.springer.com/us/book/9781493932122
*  Exploring Population Genetic Models With Recombination Using Efficient Forward-Time Simulations | Genetics
Exploring Population Genetic Models With Recombination Using Efficient Forward-Time Simulations Message Subject (Your Name) has ... Hudson, R. R., 2002 Generating samples under a Wright-Fisher neutral model of genetic variation. Bioinformatics 18: 337-338. ... Exploring Population Genetic Models With Recombination Using Efficient Forward-Time Simulations. Badri Padhukasahasram, Paul ... Exploring Population Genetic Models With Recombination Using Efficient Forward-Time Simulations. Badri Padhukasahasram, Paul ...
  http://www.genetics.org/content/178/4/2417
*  Fish eyes: modeling genetic mutations behind ocular disease - Department of Biological Sciences - Purdue University
Using zebrafish as a model, Dr Yuk Fai Leung studies the gene networks behind ocular diseases. Finding the genetic root of ... projects.croucher.org.hk/news/fish-eyes-modeling-genetic-mutations-behind-ocular-disease ...
  https://www.bio.purdue.edu/news/articles/2016/zebrafish-gene-networks.html
*  Genome-wide expression profiling data analysis to study autism genetic models | Autism Speaks
Autism SpeaksScienceGrant SearchResultsGenome-wide expression profiling data analysis to study autism genetic models ... This study aims to test that model in an attempt to explain possible risk factors of autism. Using gene expression data from ... It has been proposed that autism spectrum disorders are caused by combinations of multiple genetic variants, or mutations that ...
  https://www.autismspeaks.org/science/grants/genome-wide-expression-profiling-data-analysis-study-autism-genetic-models?destination=about-us%2Fgrant-search%2Fresults%2Ftaxonomy%3A9771%2C10861
*  Colorectal Cancer: From the Genetic Model to Posttranscriptional Regulation by Noncoding RNAs
... María Antonia Lizarbe,1 Jorge ... In this review, we first focus on colorectal carcinogenesis and on the genetic and epigenetic alterations involved. In addition ...
  https://www.hindawi.com/journals/bmri/2017/7354260/abs/
*  PPT - Genetic Model Systems : Yeast PowerPoint Presentation - ID:203314
Genetic Model Systems : Yeast. David M. Bedwell, Ph.D. Department of Microbiology BBRB 432 Phone: 934-6593 E-mail: dbedwell@uab ... genetic traits. widow's peak. genetic traits. albinism. genetic traits. attached and unattached earlobes. genetic traits. ... Genetic Testing -. lecture 8. overview of genetic testing. genetic diseases often depend on the genotype of an individual at a ... Principles of genetic engineering -. l mathias. what is genetic engineering. genetic engineering, also known as recombinant dna ...
  https://www.slideserve.com/Audrey/genetic-model-systems-yeast
*  A Genetic Model of Retinoblastoma in Zebrafish | IOVS | ARVO Journals
A Genetic Model of Retinoblastoma in Zebrafish Maura McGrail; Pavel A. Brodskiy; Elizabeth M. Whitley; Donald S. Sakaguchi; ... A Genetic Model of Retinoblastoma in Zebrafish You will receive an email whenever this article is corrected, updated, or cited ... Our zebrafish retinal tumor model provides a novel genetic system for investigating the genetics of retinoblastoma onset and ... Maura McGrail, Pavel A. Brodskiy, Elizabeth M. Whitley, Donald S. Sakaguchi, Jeffrey J. Essner; A Genetic Model of ...
  https://iovs.arvojournals.org/article.aspx?articleid=2352079
*  Genetic model of posterior subcapsular cataract formation | Disease Models & Mechanisms
Genetic model of posterior subcapsular cataract formation Message Subject (Your Name) has sent you a message from Disease ... Anatoly Samoylenko, Seppo Vainio and colleagues describe a novel model to assay the roles of co-regulated genes in kidney ... Your Name) thought you would like to see the Disease Models & Mechanisms web site. ... Thank you for your interest in spreading the word on Disease Models & Mechanisms. ...
  http://dmm.biologists.org/content/4/4/421.5
*  Genetic model offers elegant tool for testing Parkinson's disease therapies
... August 21, 2018, University of British Columbia ... The model-known as a VPS35 D620N knock-in (VKI)-induces the biology of a disease-causing gene rather than the symptoms of the ... The new model, developed by Farrer and his team could offer the precise tool that researchers have long hoped would deliver the ... Although the model shows no behavioral signs of Parkinson's, their new study found the changes in biology are clear and ...
  https://medicalxpress.com/news/2018-08-genetic-elegant-tool-parkinson-disease.html
*  Modelling Genetic Regulatory Networks - ePrints - Newcastle University
Full text for this publication is not currently held within this repository. Alternative links are provided below where available. ...
  http://eprint.ncl.ac.uk/pub_details2.aspx?pub_id=167806
*  Genetic Rat Models of Schizophrenia-Relevant Symptoms
While efforts should be made to evaluate the predictive validity of these genetic rat models, we propose that they have the ... lesion-induced and genetic mouse models, the present review focuses on describing the most relevant genetically-based rat ... To be considered a valid analogue of the disorder, a given model should present good face validity (i.e. similarity of symptoms ... As several recent works have already reviewed the main behavioural and developmental models, as well as the most used drug- ...
  http://www.scirp.org/journal/PaperInformation.aspx?PaperID=47392
*  New genetic models of autism point to cellular roots of disease | UCSF Department of Psychiatry
New genetic models of autism point to cellular roots of disease. December 5, 2017 - 1:21pm. *Print ... Researchers at UC San Francisco have developed a new genetic model of autism, using neurons created in the lab from patients' ... "For something as behaviorally complex and hard to quantify as autism, when we look at all the different genetic models that ... 21, 2017, in Molecular Psychiatry developed a second novel genetic model of autism. The researchers again created neurons from ...
  http://psych.ucsf.edu/node/3486
*  Scripps Research Scientists Create New Genetic Model of Premature Aging Diseases - Healthcanal.com : Healthcanal.com
Home Geriatrics and Aging Scripps Research Scientists Create New Genetic Model of Premature Aging Diseases ... scientists from the Florida campus of The Scripps Research Institute have developed a new genetic model of premature aging ... to model two rare human genetic disorders: Hutchinson-Gilford Progeria Syndrome and laminopathies. ... "This model is ready now and can be used to screen and develop chemical compounds to treat these and other age-related diseases ...
  https://www.healthcanal.com/geriatrics-aging/16640-scripps-research-scientists-create-new-genetic-model-of-premature-aging-diseases.html
*  A Convex-Risk-Measure Based Model and Genetic Algorithm for Portfolio Selection
... Weijia Wang,1 Jie Hu,1 and Ning Dong2,3 ... norms and their applications," Applied Stochastic Models in Business and Industry, vol. 23, no. 1, pp. 49-62, 2007. View at ... R. Fuss, D. G. Kaiser, and A. Zeno, "Value at risk, GARCH modelling and the forecasting of the hedge fund return volatility," ...
  https://www.hindawi.com/journals/mpe/2015/451627/ref/
*  A Convex-Risk-Measure Based Model and Genetic Algorithm for Portfolio Selection
... Weijia Wang,1 Jie Hu,1 and Ning Dong2,3 ... Furthermore, a genetic algorithm is proposed for this portfolio optimization model. At last, simulations are made on randomly ... Then a portfolio optimization model based on this risk measure is set up. ... and the results indicate that the proposed model is reasonable and the proposed algorithm is effective. ...
  https://www.hindawi.com/journals/mpe/2015/451627/abs/
*  Immunity at the forefront of the brain: A new genetic model of FTD | Science Translational Medicine
Functional characterization of a genetic variant linked to frontotemporal dementia in a murine model reveals deficits in ... Functional characterization of a genetic variant linked to frontotemporal dementia in a murine model reveals deficits in ... Functional characterization of a genetic variant linked to frontotemporal dementia in a murine model reveals deficits in ... Immunity at the forefront of the brain: A new genetic model of FTD ...
  http://stm.sciencemag.org/content/9/394/eaan5227.full
*  Qualitative Modelling of genetic networks using high level Petri nets
Qualitative Modelling of genetic networks using high level Petri nets J.-P. Comet, H. Klaudel and S. Liauzu ... The second modelling is more compact since the unique place abstracts the cell in which each token represents a specific gene ... This formalism allows us to unify the modelling of both approaches, to take advantage of all results and tools in the field of ... biological system to the model. We revisit here the tremendous work of R. Thomas in term of high-level Petri nets. It has been ...
  http://www.i3s.unice.fr/~comet/publications/ConfIntl-sans-actes/confIPG2004.html
*  Animal Models of Genetic Disorders of Myelin | Springer for Research & Development
... of myelin is afforded by the study of animals in which interference with these processes occurs as a result of genetic ... Hogan E.L., Greenfield S. (1984) Animal Models of Genetic Disorders of Myelin. In: Morell P. (eds) Myelin. Springer, Boston, MA ... Bird, T. D., Farrell, D. F., and Sumi, S. M., 1978, Brain lipid composition of the shiverer mouse: Genetic defect in myelin ... During the past decade, considerable work has been carried out on several mouse mutants with genetic defects in and limited to ...
  https://rd.springer.com/chapter/10.1007/978-1-4757-1830-0_14
*  Mouse Genetic Models Reveal Surprising Functions of IκB Kinase Alpha in Skin Development and Skin Carcinogenesis
... ... "Mouse Genetic Models Reveal Surprising Functions of IκB Kinase Alpha in Skin Development and Skin Carcinogenesis." Cancers 5 (1 ... but also demonstrates that mouse models are extremely valuable tools for revealing the mechanisms underlying these biological ...
  https://dash.harvard.edu/handle/1/11855921
*  DIGITAL.CSIC: Genetic model for the inheritance of the parthenocarpy in the tomato line '75/59'
EN] A genetic model for the parthenocarpy in the strain 75/79 was proposed in 1986 by Nuez et al. This parthenocarpic strain ... Genetic model for the inheritance of the parthenocarpy in the tomato line '75/59'. ... ANALES_19_1-2.-Genetic model.pdf. 174,47 kB. Adobe PDF. Visualizar/Abrir ... In agreement with this model, 75/79 would be homozygous for the genes pat-3 and pat-4 wich are partially recessive and with ...
  https://digital.csic.es/handle/10261/12882
*  Abstract 4951: A Genetic Model of Vascular Inflammation: Switchable Expression of Hypoxia Inducible Factor1 Alpha (HIF1a)...
Abstract 4951: A Genetic Model of Vascular Inflammation: Switchable Expression of Hypoxia Inducible Factor1 Alpha (HIF1a) ... Abstract 4951: A Genetic Model of Vascular Inflammation: Switchable Expression of Hypoxia Inducible Factor1 Alpha (HIF1a) ... Abstract 4951: A Genetic Model of Vascular Inflammation: Switchable Expression of Hypoxia Inducible Factor1 Alpha (HIF1a) ... Abstract 4951: A Genetic Model of Vascular Inflammation: Switchable Expression of Hypoxia Inducible Factor1 Alpha (HIF1a) ...
  http://circ.ahajournals.org/content/120/Suppl_18/S1028.3