November 1994). "microphthalmia, a critical factor in melanocyte development, defines a discrete transcription factor family". ... "The microphthalmia transcription factor and the related helix-loop-helix zipper factors TFE-3 and TFE-C collaborate to activate ... "The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes". The ... Microphthalmia-associated transcription factor also known as class E basic helix-loop-helix protein 32 or bHLHe32 is a protein ...
best in class Microphthalmia Transcription Factor (MITF); Clone D5 (Concentrate) - RA0207-C.1 ( Antibodies, Research Antibodies ... Microphthalmia Transcription Factor (MITF); Clone D5 (Concentrate). Species: Mouse. Immunogen: N-terminal fragment of human ...
Translocation renal cell carcinomas: an evolving entity and a member of the microphthalmia transcription factor-associated ... Translocation renal cell carcinomas: an evolving entity and a member of the microphthalmia transcription factor-associated ... Translocation renal cell carcinomas : an evolving entity and a member of the microphthalmia transcription factor-associated ... title = "Translocation renal cell carcinomas: an evolving entity and a member of the microphthalmia transcription factor- ...
Open the PDF for Microphthalmia-Associated Transcription Factor in ,span class=search-highlight,Senescence,/span, and Age- ... View article titled, Microphthalmia-Associated Transcription Factor in ,span class=search-highlight,Senescence,/span, and Age ...
Hypoxia inducible factor-1α. eNOS:. Endothelial nitric oxide synthase. MITF:. Microphthalmia-associated transcription factor. ... epidermal growth factor; PDGF: platelet-derived growth factor; HIF-1α: hypoxia inducible factor-1α; eNOS: endothelial nitric ... epidermal growth factor (EGF), platelet-derived growth factor (PDGF), hypoxia inducible factor-1α (HIF-1α), and endothelial ... Furthermore, as an endothelium-derived hyperpolarizing factor, H2S can also cause local thermal hyperaemia and reflex ...
Microphthalmia transcription factor expression in cutaneous benign, malignant melanocytic, and nonmelanocytic tumors. Am J Surg ... 33] S-100, MelanA/Mart-1(A103), tyrosinase(T311), and microphthalmia transcription factor (MITF) typically stain both the ... Constitutional factors have been shown to define the predisposition and pattern of nevus development. [4] Total nevus counts ... Factors influencing nevus density. Race, sex and UV radiation have been shown to influence nevus density. In studies from ...
Microphthalmia-Associated Transcription FactorIBA 06/01/2002 - "Histologic examination showed the classic features of CCMMT, ... and microphthalmia transcription factor.". 01/01/2014 - "Recent studies have demonstrated that cathepsin K seems to be a ... powerful marker in identifying the microphthalmia associated transcription factor (MITF) family tumors such as renal ... microphthalmia transcription factor, S100 and cyclin D1. ". ...
Microphthalmia-associated transcription factor (MITF) is a master transcription factor in melanogenesis. Besides, MITF also ... MITF is one of the key regulators for melanogenesis and it controls the gene transcription of tyrosinase, TRP-1, TRP-2, Cdc42 ... Reverse Transcription-PCR. Cellular total RNA was extracted by TRIzol reagent and quantified spectrophotometrically. Then, ... As shown in Figure 4A, α-MSH remarkably increased MITF transcription, however, no change was observed after J147 treatment, ...
MicroRNA-137 targets microphthalmia-associated transcription factor in melanoma cell lines.. Bemis LT; Chen R; Amato CM; ... DNeasy Blood & Tissue Kit (250) ACT environmental impact factor label US.. ACT environmental impact factor labels are designed ... DNeasy Blood & Tissue Kit (250) ACT environmental impact factor label UK.. DNA yields.. Genotyping of horses.. High-quality DNA ... DNeasy Blood & Tissue Kit (250) ACT environmental impact factor label UK.. DNA yields.. Genotyping of horses.. High-quality DNA ...
Melanocytes and the microphthalmia transcription factor network. Steingrímsson, E., Copeland, N.G., Jenkins, N.A. Annu. Rev. ... Biochemistry and genetics of von Willebrand factor. Sadler, J.E. Annu. Rev. Biochem. (1998) [Pubmed] ... Biochemistry and genetics of von Willebrand factor [12].. *Function and genetics of dystrophin and dystrophin-related proteins ... Evidence is growing for the role of systemic factors, such as genetics, diet, estrogen use, and bone density, and local ...
The microphthalmia transcription factor (Mitf) controls expression of the ocular albinism type 1 gene: link between melanin ... Potterf, S. B., Furumura, M., Dunn, K. J., Arnheiter, H. & Pavan, W. J. Transcription factor hierarchy in Waardenburg syndrome ... Reverse transcription-PCR. Isolation of total RNA and gDNA, cDNA synthesis and targeted preamplification on CTC-enriched ... Grahovac, J., Becker, D. & Wells, A. Melanoma cell invasiveness is promoted at least in part by the epidermal growth factor- ...
Microphthalmia-associated transcription factor regulates RAB27A gene expression and controls melanosome transport. J Biol Chem ... The microphthalmia-associated transcription factor (MITF) presents highly dynamic expression patterns in connection to ... An interesting possibility is that the activity of these two transcription factor genes could trigger expression and transcript ... Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells. Elife ...
These mutations reduce but do not eliminate the proteins normal function, impairing its role as a transcription factor. ... Microphthalmia. Mutations in one copy of the PAX6 gene can cause microphthalmia, which describes eyes that are smaller than ... These mutations reduce but do not eliminate the proteins normal function, impairing its role as a transcription factor. ... On the basis of this action, PAX proteins are called transcription factors. ...
... subtype that harbors a translocation involving a member of the microphthalmia transcription factor gene family. These ... TFE3 and TFEB, along with TFEC and MiTF, are members of the microphthalmia-associated transcription factor (MiTF) family, which ... Tumors are negative for microphthalmia-associated transcription factor (MiTF) and RCC. Nuclear overexpression of the TFEB gene ... as these tumors are considered part of the family of microphthalmia transcription factors. [2] ...
... tyrosinase and microphthalmia transcription factor (MITF) protein levels were determined by the Western blot method. ... Both the activation energy, E, and the frequency factor, k0, for the oxidation of linoleic acid mixed with ferulic acid or ... or transcriptional intermediate factor-2 (TIF-2) was most effective for estrogen-dependent induction of the chromosome- ...
A novel role for microphthalmia-associated transcription factor-regulated pigment epithelium-derived factor during melanoma ... Age-resolving osteopetrosis: a rat model implicating microphthalmia and the related transcription factor TFE3.. Weilbaecher K, ... Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor. Widlund H, ... Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor ...
Through proteome-profiling, attenuation of the microphthalmia-associated transcription factor (MITF) signaling pathway was ... is Linked to Altered Microphthalmia-associated Transcription Factor and Phospho-ERK Expression. View ORCID ProfileHusvinee ... is Linked to Altered Microphthalmia-associated Transcription Factor and Phospho-ERK Expression ... is Linked to Altered Microphthalmia-associated Transcription Factor and Phospho-ERK Expression ...
The microphthalmia-associated transcription factor (MITF) is a critical regulator of melanocyte development and differentiation ... The microphthalmia-associated transcription factor (MITF) is a critical regulator of melanocyte development and differentiation ...
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the ... Protein Aliases: Delta EF2a; MCOPS3 (Microphthalmia Syndromic type 3); sex determining region Y-box 2; SOX 2; SRY (sex ... SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 ... transcription factor activity, sequence-specific DNA binding protein binding miRNA binding sequence-specific DNA binding ...
Giant cell tumors: inquiry into immunohistochemical expression of CD117 (c-Kit), microphthalmia transcription factor, tartrate- ... Other risk factors included urinary tract infection, foreign bodies, vesicoureteral reflux and urinary stasis but not acidosis ... involvement of macrophage activation and tumor necrosis factor-alpha. Kasama, T., Kobayashi, K., Yamagata, N., Iwabuchi, H., ... involvement of macrophage activation and tumor necrosis factor-alpha [19]. ...
Furthermore, downstream players such as microphthalmia-associated transcription factor and visual system homeobox 2 were also ... Ppargc1a is a multifunctional transcriptional coactivator and has the ability to interact with different transcription factors ... epidermal growth factor receptor (Egfr), fibrillin 2 (Fbn2), Fyn proto-oncogene (Fyn), and insulin-like growth factor 2 (Igf2) ... transforming growth factor beta binding protein 4 (Ltbp-4) to regulate the targeting of transforming growth factor β (Tgf-β) in ...
... microphthalmia-associated transcription factor a (mitfa), which controls cell fate specification of melanocytes in zebrafish; ... The forkhead transcription factor gene FKHL7 is responsible for glaucoma phenotypes which map to 6p25. Nat Genet. 1998; 19:140- ... The winged-helix transcription factor FoxD3 is important for establishing the neural crest lineage and repressing melanogenesis ... The forkhead box D3 (FOXD3) gene encodes a forkhead transcription factor that plays an important role in neural crest ...
... that eventually lead to the expression of genes codifying for microphthalmia-associated transcription factor (MITF). This is a ... This induces several signalling pathways that result in the stimulation of the transcription factor AP-1, which upregulates ... Stress Factors. External stress factors (e.g., radiation) or derived from lifestyle (smoking) or disease (cold, psoriasis or ... Most of the factors related to the individual are congenital. In this regard, it is considered that some factors, notably ...
... a transcription factor belonging to the microphthalmia/transcription factor E (MiT/TFE) family of transcription factors, has ... Nutrient-sensitive transcription factors TFEB and TFE 3 couple autophagy and metabolism to the peripheral clock. EMBO J. 2019; ... MiT/TFE family of transcription factors, lysosomes, and cancer. Annu Rev Cancer Biol. 2019;3:203-222.. View this article via: ... The transcription factors TFEB and TFE3 link the FLCN-AMPK signaling axis to innate immune response and pathogen resistance. ...
... the expression and nuclear translocation of microphthalmia-associated transcription factor (MITF) as a key transcription factor ... Melanin Synthesis through Suppressing Transactivation Activity of Microphthalmia-Associated Transcription Factor ... The skin pro-inflammatory cytokines interleukin (IL)-8 and tumor necrosis factor (TNF)-α were examined to evaluate the pro- ... The New Zealand Unique Manuka Factor Honey Association, which represents New Zealand manuka honey processing companies, said it ...
The Microphthalmia-associated Transcription Factor (MiT) family proteins (MITF, TFEB, TFE3, TFEC) are considered master ... This project aims at shedding light on a potential mechanistic role of the MiT transcription factor pathway in relation to ... Crosstalk of organelles in Parkinsons disease - MiT family transcription factors as central players in signaling pathways ...
Microphthalmia Transcription Factor (MiTF). Czytaj dalej. Mesothelin. Czytaj dalej. Melan A (M). Czytaj dalej ...
Human Microphthalmia Associated Transcription Factor (MITF) ELISA Kit. SEH645Hu-1x48wellstestplate Cloud-Clone 1x48-wells test ... Human Microphthalmia Associated Transcription Factor (MITF) ELISA Kit. SEH645Hu-1x96wellstestplate Cloud-Clone 1x96-wells test ... Human Microphthalmia Associated Transcription Factor (MITF) ELISA Kit. SEH645Hu-5x96wellstestplate Cloud-Clone 5x96-wells test ... Human Microphthalmia Associated Transcription Factor (MITF) ELISA Kit. SEH645Hu-10x96wellstestplate Cloud-Clone 10x96-wells ...
The roles of microphthalmia-associated transcription factor and pigmentation in melanoma. Arch Biochem Biophys. 2014;563:28-34. ... These two promoters, at least in Jurkat cells, designated EPD NK4_1 and EPD IL32_1, are thought to support the transcription of ... Interactions between IL-32 and tumor necrosis factor alpha contribute to the exacerbation of immune-inflammatory diseases. ... A chromatin landmark and transcription initiation at most promoters in human cells. Cell. 2007;130(1):77-88. ...