Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition
Immunodeficient mouse strains display marked variability in growth of human melanoma lung metastases
The absolute NK deficiency in NOD-scid IL2Rgamma(null) animals makes this strain an excellent recipient of melanoma and ... Mice, Inbred NOD * Mice, Knockout * Mice, SCID * Recombinant Fusion Proteins / genetics * Recombinant Fusion Proteins / ... mice. NK cells were detected in all strains except NOD-scid IL2Rgamma(null), and in vitro activated scid, NOD-scid, and NOD- ... Melanoma metastases growth is delayed and variable in scid and NOD-scid mice. In contrast, NOD-scid beta2m(null) and NOD-scid ...
NOG mouse - Wikipedia
NOD/Shi inbred strain, 2) SCID, 3) IL-2Rγnull. These include: Reduced innate immunity derived from a NOD inbred strain, which ... such as nude mouse and NOD/scid mouse. Thus, the mouse can be the best model as a highly efficient recipient of human cells to ... The NOD/Shi inbred strain was first discovered by Makino et al. as autoimmune non-obese-type diabetes mice. Lack of functional ... A NOG (NOD/Shi-scid/IL-2Rγnull) mouse is a new generation of severely immunodeficient mouse, developed by Central Institute for ...
Page 1 | Search Results | Diabetes | American Diabetes Association
mice (3) * mice, inbred nod (3) * autoimmunity (2) * combined modality therapy (2) ... Open the PDF for Poly (ADP-Ribose) Polymerase Inhibition Prevents Spontaneous and Recurrent Autoimmune Diabetes in NOD Mice by ... Combination Therapy With Sirolimus and Interleukin-2 Prevents Spontaneous and Recurrent Autoimmune Diabetes in NOD Mice ... View article titled, Poly (ADP-Ribose) Polymerase Inhibition Prevents Spontaneous and Recurrent Autoimmune Diabetes in NOD Mice ...
Page 1 | Search Results | Diabetes | American Diabetes Association
mice, inbred nod (6) * viruses (6) * autoimmunity (5) * macrophages (5) * t-lymphocytes (4) ... Open the PDF for Evidence for Initial Involvement of Macrophage in Development of Insulitis in NOD Mice in another window ... Association of β-Cell-Specific Expression of Endogenous Retrovirus With Development of Insulitis and Diabetes in NOD Mouse ... Macrophages Essential for Development of β-Cell-Specific Cytotoxic Effectors and Insulitis in NOD Mice in another window ...
Current DRC investigators
Autoantigens, Diabetes Mellitus Type 1, CD4-Positive T-lymphocytes, Inbred NOD mice, islets of Langerhans. The overall research ... Recently, she was involved in work demonstrating that some adipocytes in the major white fat depots of mice and humans are ... His main research focus is on mouse models of autoimmunity, and type 1 diabetes in particular. His work is aimed at ... His lab has developed multiple mouse models of lipid storage and secretion that have uncovered novel tissue and innate immune ...
Division of Nephrology, Hypertension & Apheresis - Research output
- Research Profiles at Washington University School of...
Sequence Detail
Sequenced Mouse Inbred Strain Genome Meta-data. Organism. mouse. Strain/Species. NOD/ShiLtJ ... Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse ... Annotation of mouse strain NOD/ShiLtJ genome assembly provided by GENCODE consortium. Distributed via Ensembl Release 103. Gene ... J:259852 Mouse Genome Informatics and the WTSI Mouse Genomes Project, MGI Strain Genome Feature and Gene Model Load. Database ...
Guo, Beichu | Palmetto Profiles
Ek, S.<...
Transplant - Research output - Research Nebraska
Inbred NOD Mouse 80% * Chemokine Receptors 73% * Type 1 Diabetes Mellitus 58% ... IL-18 is required for self-reactive T cell expansion in NOD mice. Marleau, A. M. & Sarvetnick, N. E., May 2011, In: Journal of ... The incidence of type-1 diabetes in NOD mice is modulated by restricted flora not germ-free conditions. King, C. & Sarvetnick, ... CCR2 and CCR5 chemokine receptors differentially influence the development of autoimmune diabetes in the NOD mouse. Solomon, M. ...
Improved murine MHC-deficient HLA transgenic NOD mouse models for type 1 diabetes therapy development<...
Inbred NOD Mouse Medicine & Life Sciences 100% * Transgenic Mice Medicine & Life Sciences 72% ... NOD.β2m-/--A2.1 mice were previously used to identify β-cell autoantigens presented by this human class I variant to pathogenic ... NOD.β2m-/--A2.1 mice were previously used to identify β-cell autoantigens presented by this human class I variant to pathogenic ... NOD.β2m-/--A2.1 mice were previously used to identify β-cell autoantigens presented by this human class I variant to pathogenic ...
Reference Summary
... and NOD/Lt inbred strains of mice. Tumors presented primarily in the subcutaneous tissues of the ventral neck (74% of the ... Forty myoepitheliomas were tested by the avidin-biotin complex technique with a panel of antisera specific for mouse keratins, ... Antibodies directed against the specific mouse keratins K5, K6, and K14, and a broadly cross-reactive cytokeratin antibody ... did not show restriction fragment length polymorphisms when mouse mammary tumor virus (MMTV) cDNA or Int-1 genomic DNA probes ...
Leptin therapy in insulin-deficient type I diabetes.
Eric Meissner's research topics | Palmetto Profiles
Diabetes - Immunovirology - Research output
- Lund University
Antibiotic treatment of pregnant non-obese diabetic (NOD) mice leads to altered gut microbiota and intestinal immunological ... MafA expression preserves immune homeostasis in human and mouse islets. Singh, T., Sarmiento, L., Luan, C., Prasad, R. B., ... Immunological alteration and changes of gut microbiota after dextran sulfate sodium (DSS) administration in mice. Håkansson, Å. ...
A biomimetic five-module chimeric antigen receptor (|sup|5M|/sup|CAR) designed to target and eliminate antigen-specific T cells...
Inbred NOD Mouse 15% * Histocompatibility Antigens Class I 14% * Cytotoxic T-Lymphocytes 13% ...
Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor - Fingerprint -...
Inbred NOD Mouse 93% * Type 1 Diabetes Mellitus 68% * Immunoglobulins 67% * Proteins 28% ... Dive into the research topics of Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin ... Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor. ...
Ching-Shuen Wang - Research output - Taipei Medical University
Search results | DigiNole
Page 1 | Search Results | Diabetes | American Diabetes Association
mice, inbred nod (6) * pancreas (6) * autoimmunity (5) * endocrine pancreas (5) * insulin (4) ... Open the PDF for Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10-Secreting ,em,Lactococcus lactis,/em, ... Reversal of Diabetes in NOD Mice by Clinical-Grade Proinsulin and IL-10-Secreting Lactococcus lactis in Combination With Low- ... Oral Delivery of Glutamic Acid Decarboxylase (GAD)-65 and IL10 by Lactococcus lactis Reverses Diabetes in Recent-Onset NOD Mice ...
Taipei Medical University - Research output - Taipei Medical University
Division of Allergy & Immunology - Research output
- Research Profiles at Washington University School of Medicine
Inbred NOD Mouse 100% * Type 1 Diabetes Mellitus 72% * B-Lymphocytes 62% ... Vκ polymorphisms in NOD mice are spread throughout the entire immunoglobulin kappa locus and are shared by other autoimmune ... In vivo islet protection by a nuclear import inhibitor in a mouse model of type 1 diabetes. Moore, D. J., Zienkiewicz, J., ... Gut microbiota from twins discordant for obesity modulate metabolism in mice. Ridaura, V. K., Faith, J. J., Rey, F. E., Cheng, ...
Knud Elnegaard Josefsen - Publikationer - Region Hovedstadens forskningsportal
Corrigendum to "Large Gliadin Peptides Detected in the Pancreas of NOD and Healthy Mice following Oral Administration". Bruun, ...
Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/sCiD...
Inbred NOD Mouse 14% * SCID Mice 13% * Serum-Free Culture Media 13% ... Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/sCiD ... Angiopoietin-like 5 and IGFBP2 stimulate ex vivo expansion of human cord blood hematopoietic stem cells as assayed by NOD/sCiD ...
Involvement of CXCR4 and IL-2 in the homing and retention of human NK and NK T cells to the bone marrow and spleen of NOD/SCID...
Inbred NOD Mouse Medicine & Life Sciences 100% * Natural Killer T-Cells Medicine & Life Sciences 97% ... of NOD/SCID mice. The retention of NK and NK T cells within the spleen and BM was dependent on Gαi signaling and CXCR4 function ... of NOD/SCID mice. The retention of NK and NK T cells within the spleen and BM was dependent on Gαi signaling and CXCR4 function ... of NOD/SCID mice. The retention of NK and NK T cells within the spleen and BM was dependent on Gαi signaling and CXCR4 function ...
New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer<...
Inbred NOD Mouse Medicine & Life Sciences 44% * SCID Mice Medicine & Life Sciences 42% ... Antitumor activity of one of the selected siRNAs was confirmed by retarded tumor growth of HPV16+ cells in NOD/SCID mice when ... Antitumor activity of one of the selected siRNAs was confirmed by retarded tumor growth of HPV16+ cells in NOD/SCID mice when ... Antitumor activity of one of the selected siRNAs was confirmed by retarded tumor growth of HPV16+ cells in NOD/SCID mice when ...
Designing IgG Constructs for Tolerance to Diabetogenic * - Uniformed Services University
Inbred NOD Mouse Medicine & Life Sciences 78% * Uveitis Medicine & Life Sciences 71% ... and can both prevent and reverse autoimmune responsiveness in uveitis and EAR Preliminary results in NOD mice as a model for ... insulin B chain-IgG or a GAD-IgG construct can be used to transfect B cell blasts and provide clinical protection in NOD mice ...