*  Exercise stress alters the percentage of splenic lymphocyte subsets in response to mitogen but not in response to interleukin-1.
Mice. Mice, Inbred C3H. Mitogens / pharmacology*. Physical Exertion*. Spleen / immunology*, physiology. Chemical. ... Mice in this study were assigned to one of five treatment conditions. Two groups of mice were exposed only to the noise and ... Three groups of mice were exposed to 8 weeks of treadmill training: one group was sacrificed immediately after training, a ... 15116368 - Effects of high-intensity endurance exercise training in the g93a mouse model of amyotr.... 11673518 - C57bl/6 and ...
  http://www.biomedsearch.com/nih/Exercise-stress-alters-percentage-splenic/2790228.html
*  IGF-binding protein-5 stimulates osteoblast activity and bone accretion in ovariectomized mice.
Mice. Mice, Inbred C3H. Osteoblasts / cytology, drug effects*. Ovariectomy. Spine / cytology, drug effects. ... To evaluate whether IGFBP-5 can stimulate osteoblast activity and enhance bone accretion in a mouse model of osteoblast ... These data indicate that IGFBP-5 effectively enhances bone formation and bone accretion in OVX mice by stimulating osteoblast ... mice for 8 wk. Femur and spine bone mineral density (BMD), measured every 2 wk, showed early and sustained increases in ...
  http://www.biomedsearch.com/nih/IGF-binding-protein-5-stimulates/11440904.html
*  Effect of tacrolimus derivatives on immunosuppression.
Mice. Mice, Inbred BALB C. Mice, Inbred C3H. Mice, Inbred DBA. Polyethylene Glycols / pharmacology*. Prodrugs / pharmacology*. ...
  http://www.biomedsearch.com/nih/Effect-tacrolimus-derivatives-immunosuppression/19407973.html
*  The amyloid precursor protein is not enriched in caveolae-like, detergent-insoluble membrane microdomains - Lancaster EPrints
Mice ; Mice, Inbred C3H ; Neuroblastoma ; Phosphatidylinositol Diacylglycerol-Lyase ; Polyethylene Glycols ; Receptors, ... Caveolin could not be detected in microsomal membranes from either mouse cerebellum or SH-SY5Y cells. These observations ... Detergent-insoluble membranes from mouse cerebellum retained nearly all of the glycosylphosphatidylinositol-anchored proteins-- ... caveolae-like membranes from both mouse cerebellum and the human neuroblastoma cell line SH-SY5Y. ...
  http://eprints.lancs.ac.uk/51855/
*  The effects of colony-stimulating factor-1 on the distribution of mononuclear phagocytes in the developing osteopetrotic mouse.
Mice. Mice, Inbred C3H. Mice, Inbred C57BL. Organ Specificity. Osteoclasts / pathology. Osteopetrosis / blood, embryology, ... mouse. Fetal/neonatal mice, derived from matings of either +/csfmop females with csfmop/csfmop males or the reciprocal pairings ... 16557874 - Pathological changes in brain and other target organs of infant and weanling mice after.... 15285784 - Maternal ... gestational day-17 mothers were injected intravenously with 125I-mouse CSF-1 or human rCSF-1, and the 125I-cpm or human CSF-1 ...
  http://www.biomedsearch.com/nih/effects-colony-stimulating-factor-1/9573014.html
*  Endotoxic activities of tumor necrosis factor independent of IL1 secretion by macrophages/monocytes - Publikationsserver der...
Mice. MESH. Mice, Inbred C3H. MESH. Monocytes/physiology. MESH. Recombinant Proteins/toxicity. MESH. ... Intravenous injection of TNF resulted in a hypothermic reaction of mice within 3 to 6 hours. This reaction was not the result ... Intravenous injection of TNF resulted in a hypothermic reaction of mice within 3 to 6 hours. This reaction was not the result ... Peritoneal exudate cell cultures from endotoxin low responder mice or human peripheral mononuclear leukocyte cultures did not ...
  https://epub.uni-regensburg.de/15989/
*  Mutation of IRAK-1's KTIM abrogates its ability to bind | Open-i
Mentions: At the view of our observations, we screened the mouse IRAK-1 sequence for possible SHP-1 binding sites. We ... Mentions: At the view of our observations, we screened the mouse IRAK-1 sequence for possible SHP-1 binding sites. We ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2596967_pntd.0000305.g003&req=4
*  "Free cholesterol accumulation in macrophage membranes activates Toll-l" by Yu Sun, Minako Ishibashi et al.
Studies in macrophages from knockout mice showed major roles for TLR4, following plasma membrane cholesterol loading, and for ... mice. In mechanistic studies, cholesterol loading of macrophage plasma membranes (cyclodextrin-cholesterol) or endosomal system ... BALB/c-Apoe(-/-) mice bearing a null mutation in the Npc1 gene display prominent medial erosion and atherothrombosis, whereas ... Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Knockout; Microphthalmia-Associated Transcription Factor; Phosphorylation; ...
  https://escholarship.umassmed.edu/infdis_pp/59/
*  Cancers | Free Full-Text | Mechanism of Cancer Growth Suppression of Alpha-Fetoprotein Derived Growth Inhibitory Peptides (GIP...
New York State mouse cell line; GWI-1 = New York State mouse mammary tumor; E2 = estradiol; C3H = inbred mouse cell line).. ... New York State mouse cell line; GWI-1 = New York State mouse mammary tumor; E2 = estradiol; C3H = inbred mouse cell line). ... Human cancer cell lines, tumor-bearing C3H mice, chemo-drug conjugation; Human cancer cell culture lines. GIP-34 and GIP-8 ... Mouse, Human AFP AFP-derived peptides, GIP-34, GIP-8. Immature uterus, MCF-7 breast cancer cells, NYLAR mouse ascites tumor-6WI ...
  http://www.mdpi.com/2072-6694/3/2/2709/htm
*  DCs derived from TLR-4-deficient mice are not sensiti | Open-i
A) Bone marrow-derived DCs were obtained from either C3H/HeN (wild-type) and C3 ... DCs derived from TLR-4-deficient mice are not sensitive to sHA stimulation. ( ... Mice. *Mice, Inbred C3H. *Mice, Inbred C57BL. *Mitogen-Activated Protein Kinases/metabolism ... Mentions: The mouse strains C3H/HeJ and C57BL10/ScCr are nonresponsive to LPS due to a mutation or lack of the TLR-4 receptor, ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196009_001858f6&req=4
*  "Genetic disassociation of autoimmunity and resistance to costimulation" by Todd Pearson, Thomas G. Markees et al.
Further analyses revealed that the F(1) mice shared the dendritic cell maturation defects and abnormal CD4(+) T cell responses ... We conclude that resistance to allograft tolerance induction in the NOD mouse is not a direct consequence of overt autoimmunity ... Unexpectedly, we observed that (NOD x C57BL/6)F(1) mice, which have no diabetes, nonetheless resist prolongation of skin ... The outcomes of tolerance induction protocols tested in NOD mice may not accurately predict outcomes in human subjects. ...
  https://escholarship.umassmed.edu/gsbs_sp/972/
*  Expression of genes encoding fat transport and storage | Open-i
Expression of genes encoding fat transport and storage proteins in ileal mucosa of mice harboring a simplified human intestinal ... n = 8 mice per group. *, P , 0.05, and **, P , 0.01, for obese SIHUMI or Cra mice versus less obese SIHUMIw/oCra mice ( ... n = 8 mice per group. *, P , 0.05, and **, P , 0.01, for obese SIHUMI or Cra mice versus less obese SIHUMIw/oCra mice ( ... mice than in SIHUMIw/oCra mice (Fig. 5B). Transcription of Fatp4 and Plin2 was increased in ileal mucosa of SIHUMI mice but not ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4196224_mbo0051420090005&req=4
*  Intravenous administration of STAg causes production of | Open-i
Mice. *Mice, Inbred C3H. *Mice, Inbred C57BL. *Mice, Inbred CBA. *Mice, Knockout ... Spleen cell suspensions from mice injected with STAg, but not from uninjected mice or from mice injected with PBS alone, ... Spleen cell suspensions from mice injected with STAg, but not from uninjected mice or from mice injected with PBS alone, ... Mice from the indicated strains were intravenously injected with 25 μg STAg. Where indicated (+), mice were intraperitoneally ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2199158_JEM.971614f2b&req=4
*  The total cell count of the H33342-stained blastocyst. | Open-i
Mice. *Mice, Inbred C3H. *Mice, Inbred C57BL. *Necrosis. *Phosphorylation. *Zygote/drug effects ... IGF-1/IGFBP-1 increases blastocyst formation and total blastocyst cell number in mouse embryo culture and facilitates the ... IGF-1/IGFBP-1 increases blastocyst formation and total blastocyst cell number in mouse embryo culture and facilitates the ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC239990_1471-2121-4-14-3&req=4
*  macrophages cultured with mouse serum (MS) have a dif | Open-i
macrophages cultured with mouse serum (MS) have a different morphologyappearance, higher number of vesicle-like organelles and ... Mice, Inbred C3H. *Microscopy, Electron, Scanning. *Microscopy, Electron, Transmission. *Nitric Oxide/biosynthesis ... Culture of mouse peritoneal macrophages with mouse serum induces lipid bodies that associate with the parasitophorous vacuole ... Culture of mouse peritoneal macrophages with mouse serum induces lipid bodies that associate with the parasitophorous vacuole ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4238769_0074-0276-mioc-109-6-0767-gf01&req=4
*  Analysis of TNF-α production by DCs in response to sHA | Open-i
Mice. *Mice, Inbred C3H. *Mice, Inbred C57BL. *Mitogen-Activated Protein Kinases/metabolism ... Bone marrow-derived DCs from C3H/HeJ and C57BL/10ScCr mice carrying mutant TLR-4 alleles were nonresponsive to sHA-induced ... Bone marrow-derived DCs from C3H/HeJ and C57BL/10ScCr mice carrying mutant TLR-4 alleles were nonresponsive to sHA-induced ... Conversely, DCs from TLR-2-deficient mice were still susceptible to sHA. In accordance, addition of an anti-TLR-4 mAb to human ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2196009_001858f2c&req=4
*  A Longitudinal Study of the Effect of Genistein on Bone in Two Different Murine Models of Diminished Estrogen-Producing Capacity
Genetic effects for femoral biomechanics, structure, and density in C57BL/6J and C3H/HeJ inbred mouse strains. Journal of Bone ... G versus OVX mice. The VCD-treated mice retained a similar cortical thickness and BMDs similar to SHM mice up to 30-wk-age or ... Tibia length was increased in OVX mice relative to SHM and SVG mice. VCD-treated mice exhibited similar bone lengths to SHM ... Also, two OVX mice identified as having an ovary inadvertently left in place and two O + G mice with large fluid filled sacs at ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2951124/
*  tHRF antiserum interferes with tick feeding and B. burg | Open-i
Mice, Inbred C3H. *RNA, Messenger/genetics. *RNA, Small Interfering/genetics. *Reverse Transcriptase Polymerase Chain Reaction ... Ticks engorging on tHRF antiserum-treated mice weighed significantly less than ticks that fed on control mice (Figure 3A). The ... Ticks engorging on tHRF antiserum-treated mice weighed significantly less than ticks that fed on control mice (Figure 3A). The ... burgdorferi burden in mice.Interfering with tHRF by actively immunizing mice with recombinant tHRF, or passively transferring ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2991271_ppat.1001205.g003&req=4
*  The development of inter-strain variation in cortical and trabecular traits during growth of the mouse lumbar vertebral body |...
Bone traits were quantified for lumbar vertebral bodies of female A/J, C57BL/6J (B6), and C3H/HeJ (C3H) inbred mouse strains ... Establishing the temporal changes in bone morphology for three inbred mouse strains revealed that genetic variation in adult ... Comparing early postnatal differences in morphology of lumbar vertebral bodies for three inbred mouse strains identified ... These early coordinate changes defined the phenotypic differences among the inbred mouse strains. ...
  https://link.springer.com/article/10.1007%2Fs00198-016-3801-6
*  Direct Evidence for a Crucial Role of the Arterial Wall in Control of Atherosclerosis Susceptibility | Circulation
Background- Inbred mouse strains C57BL/6J (B6) and C3H/HeJ (C3H) exhibit marked differences in atherosclerosis susceptibility. ... mice with C3H/HeJ mice, followed by 12 sequential backcrossings with C3H/HeJ mice. F1 mice were generated by crossing female B6 ... Mice. Female 8-week-old B6.apoE−/− and C3H.apoE−/− mice were used as aorta donors; 10-week-old female F1 mice between the 2 ... Inbred mouse strains C57BL/6J (B6) and C3H/HeJ (C3H) exhibit marked differences in atherosclerosis susceptibility. This study ...
  http://circ.ahajournals.org/content/114/22/2382
*  Chronic ketamine impairs fear conditioning and produces long-lasting reductions in auditory evoked potentials
Ketamine exposure in adult mice leads to increased cell death in C3H, DBA2 and FVB inbred mouse strains. Drug Alcohol Depend. ... The effects of ketamine vary among inbred mouse strains and mimic schizophrenia for the P80, but not P20 or N40 auditory ERP ... Inhibition of auditory evoked potentials and prepulse inhibition of startle in DBA/2J and DBA/2Hsd inbred mouse substrains. ... Mice were housed four or five per cage until electrode implantation, after which each mouse was housed singly. One ketamine- ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2726963/?lang=en-ca
*  Patent US5405772 - Medium for long-term proliferation and development of cells - Google Patents
C3H, C57Bl/6, Balb/c, and DBA/2 are inbred strains of mice; CD-1 is an outbred strain of mouse; while B6D2F1 (BDF1) and B6C3F1 ... 7 shows that the serum-free medium supported hematopoiesis from all strains of mice tested, whether they were inbred, outbred ... A mutant strain of mice can be used in which the CSF-1 gene (B6C3Fe-a/a-op/op mouse strain) or the gene for its receptor or ... Mouse collagen IV (Sigma) was used at a range of concentrations from 0-15 μg/cm2, whereas mouse fibronectin (Sigma) was used at ...
  http://www.google.com/patents/US5405772?dq=U.S.+Patent+
*  Porins of Borrelia burgdorferi
Mice, Mice; Inbred C3H, Models; Molecular, Molecular Sequence Data, Multigene Family, Sequence Homology; Amino Acid, Species ... The transcription of p13 and other gene family members during in vitro growth and in a mouse infection model was therefore ... The transcription of the paralogues of gene family 48 during in vitro culturing and in a mouse infection model was also ... Finally, p13 and bbi31 are the only members of gene family 48 that are transcribed in mice, suggesting their importance during ...
  http://umu.diva-portal.org/smash/record.jsf?pid=diva2:144383
*  Differential neurosensitivity to the discriminative stimulus properties of ethanol in C57BL/6J and C3H/He mice. - PubMed - NCBI
The purpose of this study was to compare sensitivity to the discriminative stimulus effects of ethanol in two inbred mouse ... namely C57BL/6J and C3H/He mice.. METHODS: Adult male C57BL/6J and C3H/He mice were trained to discriminate between ethanol and ... Results indicate that ethanol discrimination was more readily acquired and maintained in C57BL/6J mice than C3H/He mice. ... This deficit in acquisition was overcome when the training dose was increased to 2.0 g/kg for C3H/He mice. In a second ...
  https://www.ncbi.nlm.nih.gov/pubmed?term=15166645