Contribution of matrilysin (MMP-7) to the metastatic pathway of human colorectal cancers | Gut
matrix metalloproteinase. MT1-MMP. membrane type-1 matrix metalloproteinase. SDS. sodium dodecyl sulphate. ... 1996) Matrix metalloproteinase 2 (MMP-2) and matrix metalloproteinase 9 (MMP-9) type IV collagenases in colorectal cancer. ... 1995) Distinct pattern of matrix metalloproteinase 9 and tissue inhibitor of metalloproteinase 1 mRNA expression in human ... 1996) Matrix metalloproteinases and tumour invasion: from correlation and causality to the clinic. Semin Cancer Biol 7:147-154. ...http://gut.bmj.com/content/45/2/252
Matrix Metalloproteinase-7 Regulates Cleavage of Pro-Nerve Growth Factor and Is Neuroprotective following Kainic Acid-Induced...
Matrix Metalloproteinase-7 Regulates Cleavage of Pro-Nerve Growth Factor and Is Neuroprotective following Kainic Acid-Induced ... ProNGF can be extracellularly processed to NGF by the enzyme matrix metalloproteinase 7 (MMP-7) (Smith et al., 1995; Lee et al ... Matrix Metalloproteinase-7 Regulates Cleavage of Pro-Nerve Growth Factor and Is Neuroprotective following Kainic Acid-Induced ... Matrix Metalloproteinase-7 Regulates Cleavage of Pro-Nerve Growth Factor and Is Neuroprotective following Kainic Acid-Induced ...http://www.jneurosci.org/content/32/2/703.full
Allele-Specific Regulation of Matrix Metalloproteinase-7 Promoter Activity Is Associated With Coronary Artery Luminal...
Several groups of proteolytic enzymes are able to degrade components of the extracellular matrix. Matrix metalloproteinases ( ... Role of matrix metalloproteinases in abdominal aortic aneurysms. Ann N Y Acad Sci. 1996; 800: 157-174. ... Henney AM, Ye S, Zhang B, Jormsjo S, Whatling C, Eriksson P, Hamsten A. Genetic diversity in the matrix metalloproteinase ... An enhanced expression of matrix metalloproteinase (MMP)-7 has previously been demonstrated in atherosclerotic and aneurysmal ...http://atvb.ahajournals.org/content/21/11/1834
北京大学医学部机构知识库(IR@PKUHSC): Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation...
Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation of c-Fos via ERK1/2 and ... Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation of c-Fos via ERK1/2 and ... We have previously observed that TF/FVIIa upregulates matrix metalloproteinase-7 (MMP-7) expression at the transcriptional ... MATRIX-METALLOPROTEINASE-7 英文摘要: Increased expression of tissue factor (TF) is associated with tumor invasion and metastasis in ...http://ir.bjmu.edu.cn/handle/400002259/61009
CiNii 論文 - Auraptene Decreases the Activity of Matrix Metalloproteinases in Dextran Sulfate...
Expression of matrix metalloproteinases-2 and -9 in intestinal tissue of patients with inflammatory bowel diseases GAO Q. ... The expression of matrix metalloproteinase matrilysin indicates the degree of inflammation in ulcerative colitis MATSUNO KEIKI ... Matrilysin (matrix metalloproteinase-7) expression in ulcerative colitis-related tumorigenesis NEWELL K. J. ... Auraptene Decreases the Activity of Matrix Metalloproteinases in Dextran Sulfate Sodium-Induced Ulcerative Colitis in ICR Mice ...https://ci.nii.ac.jp/naid/10018524287
Genetic Removal of Matrix Metalloproteinase 9 Rescues the Symptoms of Fragile X Syndrome in a Mouse Model | Journal of...
2001) Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human fetal testis and ovary. Mol Hum Reprod 7: ... 2006) Effects of extracellular matrix degrading proteases matrix metalloproteinases 3 and 9 on spatial learning and synaptic ... Genetic Removal of Matrix Metalloproteinase 9 Rescues the Symptoms of Fragile X Syndrome in a Mouse Model. Harpreet Sidhu, ... 2006) Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory. J Neurosci 26:1923- ...http://www.jneurosci.org/content/34/30/9867
DBGET Search Result: KEGG Matrix metalloproteinase
K08001 matrix metalloproteinase-23 (CA-MMP) [EC:3.4.24.-] , (RefSeq) MMP23B, MIFR, MIFR-1, MMP22, MMP23A; matrix ... K07994 matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-] , (RefSeq) MMP13, CLG3, MANDP1, MDST, MMP-13; matrix ... K08004 matrix metalloproteinase-26 (matrilysin-2, endometase) [EC:3.4.24.-] , (RefSeq) MMP26; matrix metallopeptidase 26 ... metalloproteinase-1; matrix metalloproteinase pump 1; MMP 7; PUMP-1 proteinase; PUMP; metalloproteinase pump-1; putative ...http://www.genome.jp/dbget-bin/www_bfind_sub?mode=bfind&max_hit=1000&dbkey=kegg&keywords=Matrix+metalloproteinase
Pro-inflammatory effects of matrix metalloproteinase 7 in acute inflammation Roosmarijn Vandenbroucke (UGent), Ineke Vanlaere ( ...https://biblio.ugent.be/publication?q=keyword+exact+%22EPIDERMAL-GROWTH-FACTOR%22
In vivo effects of insulin and free fatty acids on matrix metalloproteinases in rat aorta. - Semantic Scholar
A part of this increased risk may be due to enhanced activation of matrix metalloproteinases (MMPs). Here, we have examined the ... This may, over time, increase degradation of extracellular matrix and together with inflammatory changes promote development of ... Insulin augments matrix metalloproteinase-9 expression in monocytes.. *Arne Fischoeder, Heike Meyborg, Dietger Stibenz, Eckart ... The Important Roles of Matrix Metalloproteinases in the Pathophysiology of Obesity. *RADU MIHAIL MIRICA, MIHAI IONESCU, +6 ...https://www.semanticscholar.org/paper/In-vivo-effects-of-insulin-and-free-fatty-acids-on-Boden-Song/e45fa8ba18503ff1f8357fea03d07a7eb7719135
Medical Sciences | Free Full-Text | Prognosis and Follow-Up of Idiopathic Pulmonary Fibrosis | HTML
Matrix metalloproteinase 7 (MMP-7) has been proved to be a useful marker for the decline of the FVC and also for the ... matrix metalloproteinase 9; MUC5B: mucin 5B; CCL18: Chemokine (C-C motif) ligand 18; CXCL13: chemokine (C-X-C motif) ligand 13 ... matrix metalloproteinase 7; LOXL2: lysyl oxidase-like-2; ICAM-1: intercellular adhesion molecule 1; VCAM-1: vascular cell ... The increase of the matrix metalloproteinase 9 (MMP-9) in the bronchoalveolar lavage (BAL) has been associated with rapid ...http://www.mdpi.com/2076-3271/6/2/51/htm
Matrix metalloproteinases and inflammatory diseases of the central nervous system | Springer for Research & Development
Matrix metalloproteinases (MMPs) are involved in the pathogenesis of several diseases of the central nervous system (CNS) that ... Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 ... a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). J Biol Chem 276: ... Wetzel M, Rosenberg GA, Cunningham LA (2003) Tissue inhibitor of metalloproteinases-3 and matrix metalloproteinase-3 regulate ...https://rd.springer.com/chapter/10.1007/978-3-7643-8585-9_8
A Tale of Two Joints: The Role of Matrix Metalloproteases in Cartilage Biology
... matrix metalloproteinase-8 (MMP-8), matrix metalloproteinase-9 (MMP-9), matrix metalloproteinase-13 (MMP-13), and matrix ... 6. Matrix Metalloproteinases in Response to Mechanical Insult. Activation of matrix metalloproteinases, especially MMP-13, is ... 2. The Role of Matrix Metalloproteinases in Healthy Cartilage. Seven matrix metalloproteinases have been shown to be expressed ... "Matrix metalloproteinases, a disintegrin and metalloproteinases, and a disintegrin and metalloproteinases with thrombospondin ...https://www.hindawi.com/journals/dm/2016/4895050/
Human Total MMP-7 Quantikine ELISA Kit DMP700: R&D Systems
View Human Total MMP-7 Quantikine ELISA Kit (DMP700) datasheet. ... Elevated serum matrix metalloproteinase-3 and -7 in H. pylori- ... Matrix metalloproteinase-7 as a marker of metastasis and predictor of poor survival in bladder cancer.. Authors: Szarvas T, ... Urinary matrix metalloproteinase-7 level is associated with the presence of metastasis in bladder cancer.. Authors: Szarvas T, ... Circulating matrix metalloproteinase-7: an early or metastatic marker for renal cell carcinoma?. Authors: Jung K, Ramankulov A ...https://www.rndsystems.com/products/human-total-mmp-7-quantikine-elisa-kit_dmp700
The role of matrix metalloproteinase-7 in redefining the gastric microenvironment in response to Helicobacter pylori.. Authors: ... Analyst 2018 Sep 7. Epub 2018 Sep 7.. Department of Physics, Oliver Lodge Laboratory, University of Liverpool, Liverpool, L69 ... Stimulation of MMP-7 (matrilysin) by Helicobacter pylori in human gastric epithelial cells: role in epithelial cell migration. ... Epub 2006 Aug 7.. Division of Gastroenterology, Department of Medicine, University of Massachusetts Medical School, Worcester, ...https://www.pubfacts.com/author/Mark+Pritchard
Interleukin-10 Induced Activating Transcription Factor 3 Transcriptional Suppression of Matrix Metalloproteinase-2 Gene...
Akt1 induces extracellular matrix invasion and matrix metalloproteinase-2 activity in mouse mammary epithelial cells. Cancer ... Matrix metalloproteinase-7-dependent release of tumor necrosis factor-α in a model of herniated disc resorption. J Clin Invest ... Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN. Oncogene 2001;20: ... Inhibition of matrix metalloproteinase 9 expression by a ribozyme blocks metastasis in a rat sarcoma model system. Cancer Res ...http://mcr.aacrjournals.org/content/2/7/403
Optical Imaging of Cancer-Related Proteases Using Near-Infrared Fluorescence Matrix Metalloproteinase-Sensitive and Cathepsin B...
Localization of matrix metalloproteinase MMP-2 to the surface of invasive cells by interaction with integrin alpha v beta 3. ... Tumor-derived matrix metalloproteinase-13 (MMP-13) correlates with poor prognoses of invasive breast cancer. BMC Cancer. 2008;8 ... Matrix metalloproteinase expression is related to angiogenesis and histologic grade in spindle cell soft tissue neoplasms of ... Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine ...http://thno.org/v02p0179.htm
Circulation Editors' Picks | Circulation
Matrix Metalloproteinase-7 and ADAM-12 (a Disintegrin and Metalloproteinase-12) Define a Signaling Axis in Agonist-Induced ... Matrix Metalloproteinase-7 and ADAM-12 (a Disintegrin and Metalloproteinase-12) Define a Signaling Axis in Agonist-Induced ... Matrix metalloproteinase-7 and ADAM-12 (a disintegrin and metalloproteinase-12) define a signaling axis in agonist-induced ... Matrix Metalloproteinase-7 and ADAM-12 (a Disintegrin and Metalloproteinase-12) Define a Signaling Axis in Agonist-Induced ...http://circ.ahajournals.org/content/124/16/e415
Regulation of programmed-death ligand in the human head and neck squamous cell carcinoma microenvironment is mediated through...
Milner JM and Cawston TE: Matrix metalloproteinase knockout studies and the potential use of matrix metalloproteinase ... Several matrix metalloproteinases (MMPs) were found to be upregulated in HNSCC; in particular, MMP-7 and -13 were upregulated ... Matrix metalloproteinase (MMP) expression in head and neck squamous cell carcinoma (HNSCC) cell lines (OSC-20, OSC-19 and ... Tubulin inhibitor increases matrix metalloproteinase-13 (MMP-13) expression on R/M head and neck squamous cell carcinoma (HNSCC ...https://spandidos-publications.com/ijo/52/2/379
Browsing Biochemistry and Cell Biology by Title
Matrilysin/matrix metalloproteinase-7(MMP7) cleavage of perlecan/HSPG2 creates a molecular switch to alter prostate cancer cell ...https://scholarship.rice.edu/handle/1911/64813/browse?rpp=20&sort_by=1&type=title&etal=-1&starts_with=I&order=ASC
Browsing Bioengineering by Title
Matrilysin/matrix metalloproteinase-7(MMP7) cleavage of perlecan/HSPG2 creates a molecular switch to alter prostate cancer cell ... Measurement of mechanical tractions exerted by cells within three-dimensional matrices Legant, Wesley R.; Miller, Jordan S.; ...https://scholarship.rice.edu/handle/1911/8304/browse?rpp=20&sort_by=1&type=title&etal=-1&starts_with=M&order=ASC
Browsing Biochemistry and Cell Biology Publications by Title
Matrilysin/matrix metalloproteinase-7(MMP7) cleavage of perlecan/HSPG2 creates a molecular switch to alter prostate cancer cell ... It is evolutionarily conserved and abundantly expressed in the extracellular matrix (ECM), on the cell ... ...https://scholarship.rice.edu/handle/1911/64864/browse?rpp=20&order=ASC&sort_by=1&etal=-1&type=title&starts_with=G
JCI - Fragile X syndrome: causes, diagnosis, mechanisms, and therapeutics
Matrix metalloproteinase 9 (MMP9) mRNA is among the many putative FMRP target mRNAs with increased translation in FXS (123). ... Matrix metalloproteinase-7 disrupts dendritic spines in hippocampal neurons through NMDA receptor activation. J Neurochem. 2006 ... Claudia Bagni,1,2,3 Flora Tassone,4,5 Giovanni Neri,6 and Randi Hagerman5,7 1Katholieke Universiteit Leuven, Center for Human ... The fragile X mutation is the most common single genetic cause of autism, occurring in 1% to 6% of boys with ASD (7). ...https://www.jci.org/articles/view/63141
Tamoxifen downregulatesTGF‐β1 protein levels via matrix metalloproteinase activity in breast cancer in vivo
1. Effects of sex steroids and tamoxifen on matrix metalloproteinase activity and generation of endostatin in the breast. Open ... Tamoxifen downregulatesTGF‐β1 protein levels via matrix metalloproteinase activity in breast cancer in vivo. Nilsson, Ulrika W ... Matrix metalloproteinases are potent matrixdegrading enzymes that affect several steps in tumor progression including ... Angiogenesis, Breast cancer, TGF-β1, Endostatin, Estradiol, Mammary gland, Matrix metalloproteinases, MCF-7, Microdialysis, ...http://liu.diva-portal.org/smash/record.jsf?pid=diva2:23708
Matrix Metalloproteinases and Minocycline: Therapeutic Avenues for Fragile X Syndrome
... Saul S. Siller1,2 and Kendal Broadie1 ... A. Page-McCaw, A. J. Ewald, and Z. Werb, "Matrix metalloproteinases and the regulation of tissue remodelling," Nature Reviews ... A. Page-McCaw, J. Serano, J. M. Santë, and G. M. Rubin, "Drosophila matrix metalloproteinases are required for tissue ... A. Page-McCaw, "Remodeling the model organism: matrix metalloproteinase functions in invertebrates," Seminars in Cell and ...https://www.hindawi.com/journals/np/2012/124548/
Clinical Trials sub-cluster 83
Background: Matrix metalloproteinase-9 (MMP-9) and its inhibitor tissue inhibitor of metalloproteinase-1 (TIMP-1) are involved ... Enhanced Exhalation of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Patients ... ... Matrix metalloproteinases and their tissue inhibitors play a key role in the pathogenesis of adult-onset multiple sclerosis, ... We determined serum levels of matrix metalloproteinase-7, matrix metalloproteinase-9, and tissue ... ...http://www.biomedsearch.com/cluster/19/Clinical-Trials/sub-83-p2.html