Loading...


*  Matrix Metalloproteinase-12 MMP-12 Inhibitor | GreenMedInfo
Matrix Metalloproteinase-13 (MMP-13) Inhibitor, Matrix metalloproteinase-2 (MMP-2) inhibitor, Matrix metalloproteinase-9 (MMP-9 ... 4 Abstracts with Matrix Metalloproteinase-12 (MMP-12) Inhibitor Research. Filter by Study Type. Animal Study. ... Pharmacological Actions : Matrix Metalloproteinase-12 (MMP-12) Inhibitor. Problem Substances : Tobacco: Smoking, Tobacco Smoke ... 1 Substances Researched for Matrix Metalloproteinase-12 (MMP-12) Inhibitor Name. AC. CK. Focus. ...
  http://www.greenmedinfo.com/pharmacological-action/matrix-metalloproteinase-12-mmp-12-inhibitor
*  Synergistic Expression of Histone Deacetylase 9 and Matrix Metalloproteinase 12 in M4 Macrophages in Advanced Carotid Plaques. ...
... and matrix metalloproteinase 12 (MMP12) in human plaque are not known. This was a prospective cohort study. Genome wide ...
  https://www.sigmaaldrich.com/catalog/papers/28343758
*  Matrix metalloproteinase 12 (MMP12) polyclonal antibody - Allele Biotech
Reagents, Tools and Custom Services for molecular biology, specializing in the fields of Nano-Antibody development (nAb), Cellular Reprogramming (iPSC), Genome Editing, Fluorescent Proteins, RNAi, Viral Packaging and Protein expression.
  http://www.allelebiotech.com/matrix-metalloproteinase-12-mmp12-polyclonal-antibody/
*  Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic...
To compare the selective matrix metalloproteinase inhibitor BAY 12-9566 with the nucleoside analog gemcitabine in the treatment ... Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic ... There were 277 patients enrolled onto the study, 138 in the BAY 12-9566 arm and 139 in the gemcitabine arm. The rates of ... The median survival for the BAY 12-9566 arm and the gemcitabine arm was 3.74 months and 6.59 months, respectively (P ,.001; ...
  https://www.ncbi.nlm.nih.gov/pubmed/12947065
*  Loss of Matrix Metalloproteinase-9 or Matrix Metalloproteinase-12 Protects Apolipoprotein E-Deficient Mice Against...
Loss of Matrix Metalloproteinase-9 or Matrix Metalloproteinase-12 Protects Apolipoprotein E-Deficient Mice Against ... Loss of Matrix Metalloproteinase-9 or Matrix Metalloproteinase-12 Protects Apolipoprotein E-Deficient Mice Against ... Loss of Matrix Metalloproteinase-9 or Matrix Metalloproteinase-12 Protects Apolipoprotein E-Deficient Mice Against ... Loss of Matrix Metalloproteinase-9 or Matrix Metalloproteinase-12 Protects Apolipoprotein E-Deficient Mice Against ...
  http://circ.ahajournals.org/content/109/11/1408
*  Impaired Coronary Collateral Growth in the Metabolic Syndrome Is in Part Mediated by Matrix Metalloproteinase 12-Dependent...
Here, we sought to determine whether matrix metalloproteinases (MMPs) negatively regulate CCG in the metabolic syndrome via ... Impaired Coronary Collateral Growth in the Metabolic Syndrome Is in Part Mediated by Matrix Metalloproteinase 12-Dependent ... Impaired Coronary Collateral Growth in the Metabolic Syndrome Is in Part Mediated by Matrix Metalloproteinase 12-Dependent ... Impaired Coronary Collateral Growth in the Metabolic Syndrome Is in Part Mediated by Matrix Metalloproteinase 12-Dependent ...
  http://atvb.ahajournals.org/content/early/2013/04/18/ATVBAHA.113.301533
*  Abstract 9085: Matrixmetalloproteinase-12 Regulates the Antiviral Immune Response During Viral Myocarditis Through Interaction...
Matrix Metalloproteinase (MMP)-12 activity has been attributed to cleavage of cytokines, and digestion of extracellular matrix ... Abstract 9085: Matrixmetalloproteinase-12 Regulates the Antiviral Immune Response During Viral Myocarditis Through Interaction ... Abstract 9085: Matrixmetalloproteinase-12 Regulates the Antiviral Immune Response During Viral Myocarditis Through Interaction ... Abstract 9085: Matrixmetalloproteinase-12 Regulates the Antiviral Immune Response During Viral Myocarditis Through Interaction ...
  http://circ.ahajournals.org/content/122/Suppl_21/A9085
*  Overexpression of cathepsin f, matrix metalloproteinases 11 and 12 in cervical cancer | BMC Cancer | Full Text
Matrix metalloproteinases (MMPs) and cathepsins play a central role on the enhancement of tumor-induced angiogenesis, cell ... Nevertheless, no other metalloproteinases or cathepsins have been yet related with the progression and/or invasion of this type ... TIMP1, Integrins alpha 1 and 4, cadherin 2 and 11, Cathepsins F, B L2, MMP 9, 10 11 and 12 were upregulated and Cathepsin S, L ... Kato Y, Yamashita T, Ishikawa M: Relationship between expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 ...
  https://0-bmccancer-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/1471-2407-5-68
*  CHEMBL502896 Compound Report Card
Matrix metalloproteinase 12 Homo sapiens 0.971 CHEMBL2274 Sphingosine 1-phosphate receptor Edg-8 Homo sapiens 0.940 ...
  https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL502896
*  Inhibition of interleukin-1alpha-induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by...
... degrade cartilage oligomeric matrix protein (COMP) to produce fragments similar to those found in synovial fluid (SF) from ... OBJECTIVE To determine whether matrix metalloproteinases (MMPs) degrade cartilage oligomeric matrix protein (COMP) to produce ... potential role for matrix metalloproteinases in the generation of cartilage oligomeric matrix protein fragments in arthritic ... induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by matrix metalloproteinase inhibitors: ...
  https://www.semanticscholar.org/paper/Inhibition-of-interleukin-1alpha-induced-cartilage-Ganu-Goldberg/47e2a0c79e28f167c6d8fa6605924d88f5c10d24
*  Open Access Rheumatology: Research and Reviews | Volume 1 - Dove Press
Basic fibroblast growth factor induces matrix metalloproteinase-13 via ERK MAP kinase-altered phosphorylation and sumoylation ... The emerging roles of ADAMTS-7 and ADAMTS-12 matrix metalloproteinases Edward A Lin, Chuan-ju Liu ...
  https://www.dovepress.com/open-access-rheumatology-research-and-reviews-archive59-v96
*  A large lung gene expression study identifying IL1B as a novel player in airway inflammation in COPD airway epithelial cells |...
Alterations of inflammatory chemokine and matrix metalloproteinase mRNA levels in BAL cells from HIV-infected COPD patients. Am ... 12.. Shaykhiev R, Otaki F, Bonsu P, Dang DT, Teater M, Strulovici-Barel Y, et al. Cigarette smoking reprograms apical ...
  https://rd.springer.com/article/10.1007/s00011-018-1145-8
*  Matrix metalloproteinases 1, 2, 3 and 9 functional single-nucleotide polymorphisms in idiopathic recurrent spontaneous abortion...
IRSA has been associated with abnormalities in the remodelling of endometrial extracellular matrix, as well as aberrant matrix ... as well as aberrant matrix metalloproteinase (MMP) gene expression in endometrium of IRSA women and chorionic villi of IRSA ... has been associated with abnormalities in the remodelling of endometrial extracellular matrix, ... metalloproteinase (MMP) gene expression in endometrium of IRSA women and chorionic villi of IRSA concepti. The aim of this ...
  https://www.semanticscholar.org/paper/Matrix-metalloproteinases-1%2C-2%2C-3-and-9-functional-Pereza-Ostoji%C4%87/b57ad989adefc5edcd71a4f14b901393a838b46c
*  KEGG ENZYME: 3.4.24.65
Cloning and characterization of a unique elastolytic metalloproteinase produced by human alveolar macrophages. ... matrix metalloproteinase-12 (macrophage elastase). Genes. .g1{display:none;}. HSA: 4321(MMP12) ...
  http://www.genome.jp/dbget-bin/www_bget?EC:3.4.24.65
*  PTX3 protein Summary Report | CureHunter
Matrix Metalloproteinase 12 10. Troponin T (T, Troponin) Related Therapies and Procedures. 1. Renal Dialysis (Hemodialysis) ... 12/01/2015 - "It is known, that the long pentraxin, pentraxin 3 (PTX3) is produced at the sites of inflammation, therefore may ... 12/01/2015 - "Pentraxin 3 (PTX3), a soluble pattern recognition receptor, plays an important role in innate immunity and has ... 12/01/2015 - "Cardio-protective effects of pentraxin 3 produced from bone marrow-derived cells against ischemia/reperfusion ...
  http://www.curehunter.com/public/keywordSummaryC077657-PTX3-protein.do
*  Chronic cigarette smoke exposure generates pathogenic T cells capable of driving COPD-like disease in Rag2-/- mice. - PubMed -...
A) Matrix metalloproteinase (MMP)-12 mRNA expression in whole lungs. (B) CATHEPSIN-S mRNA expression in whole lungs. (C) Broad- ... matrix degradation, and airspace enlargement reminiscent of emphysema. ... 1 wk of smoke acclimation followed by 12 wk of exposure). At the end of the study, tissues were harvested and analyzed as ...
  https://www.ncbi.nlm.nih.gov/pubmed/20133926
*  Circulating Porphyromonas gingivalis lipopolysaccharide resets cardiac homeostasis in mice through a matrix metalloproteinase-9...
Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against ... Matrix metalloproteinase-9 protein levels were determined in the LV of WT animals by immunoblotting. Pro-MMP-9 values doubled ... Peripheral levels of matrix metalloproteinase-9, interleukin-6, and C-reactive protein are elevated in patients with acute ... Matrix metalloproteinase-9 gene deletion facilitates angiogenesis after myocardial infarction. Am. J. Physiol. Heart Circ. ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC3804276/?lang=en-ca
*  Overview of MMP Biology and Gene Associations in Human Diseases | IntechOpen
... activation of pro-matrix metalloproteinase-2 by leukolysin/membrane-type 6 matrix metalloproteinase/matrix metalloproteinase 25 ... Matrix metalloproteinase-9 and matrix metalloproteinase-2 gene polymorphisms in multiple sclerosis. Journal of Neuroimmunology ... matrix metalloproteinase-2, and tissue inhibitor of matrix metalloproteinase-1 in human abdominal aortic vascular smooth muscle ... Matrix metalloproteinase-1 and matrix metalloproteinase-3 gene promoter polymorphisms are associated with carotid artery ...
  https://www.intechopen.com/books/the-role-of-matrix-metalloproteinase-in-human-body-pathologies/overview-of-mmp-biology-and-gene-associations-in-human-diseases/
*  Frontiers | RNA-Seq Analysis of Microglia Reveals Time-Dependent Activation of Specific Genetic Programs following Spinal Cord...
2003). An adverse role for matrix metalloproteinase 12 after spinal cord injury in mice. J. Neurosci. 23, 10107-10115. ... matrix metalloproteinases 12 (Mmp12) (Wells et al., 2003) and NADPH oxidase 2 (Cybb) (Cooney et al., 2014). Here we report over ... cytoskeleton and extracellular matrix remodeling (Table S2). Pathway analysis comparison between the two lesion severities also ... Adult heterozygote CX3CR1+/GFP mice (12 weeks of age) were anesthetized by inhalation of 1.5% isoflurane gas; laminectomy was ...
  https://www.frontiersin.org/articles/10.3389/fnmol.2017.00090/full
*  Analysis of high fat diet induced genes during mammary gland development: identifying role players in poor prognosis of breast...
Matrix metalloproteinase 12, MMP12) were still significantly associated with poor prognosis (Table 3). Therefore, HFD-induced ... 2010, 12: 211-PubMedPubMed CentralView ArticleGoogle Scholar. *. Hunter DJ, Spiegelman D, Adami HO, Beeson L, van den Brandt PA ... 1989, 12: 61-68.PubMedView ArticleGoogle Scholar. *. Sasaki T, Kobayashi Y, Shimizu J, Wada M, In'nami S, Kanke Y, Takita T: ... 2011, 12: 1436-1448.View ArticleGoogle Scholar. *. Korsching E, Packeisen J, Liedtke C, Hungermann D, Wulfing P, van Diest PJ, ...
  https://bmcresnotes.biomedcentral.com/articles/10.1186/1756-0500-7-543
*  Research Tools - Qualified Antibodies - Orbigen Antibodies - Proteases - Page 1 - Allele Biotech
Matrix metalloproteinase 14 (MMP14) polyclonal antibody [[100 µg, ABP-PAB-10654]] (100 µg) MMP14 is a member of the membrane- ... Matrix metalloproteinase 15 (MMP15) polyclonal antibody [[100 µg, ABP-PAB-10862]] (100 µg) MMP15 is a member of the membrane- ... Matrix metalloproteinase 16 (MMP16) polyclonal antibody [[100 µg, ABP-PAB-10863]] (100 µg) MMP16 is a member of the membrane- ... Matrix metalloproteinase 13 (MMP13) polyclonal antibody [[100 µg, ABP-PAB-10860]] (100 µg) MMP13 cleaves type II collagen more ...
  http://www.allelebiotech.com/categories/Qualified-Antibodies/Orbigen-Antibodies/Proteases/
*  The Role of Microglia and Matrix Metalloproteinases Involvement in Neuroinflammation and Gliomas
"Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 ... R. Visse and H. Nagase, "Matrix metalloproteinases and tissue inhibitors of metalloproteinases: structure, function, and ... "Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix ... "Oligodendrocytes utilize a matrix metalloproteinase, MMP-9, to extend processes along an astrocyte extracellular matrix," Glia ...
  https://www.hindawi.com/journals/jir/2013/914104/ref/
*  UPENN Biomedical Graduate Studies | Richard K. Assoian
Matrix metalloproteinase-12 is an essential mediator of acute and chronic arterial stiffening. Scientific Reports 5: 17189, ... A FAK-Cas-Rac-Lamellipodin Signaling Module Transduces Extracellular Matrix Stiffness into Mechanosensitive Cell Cycling. ... N-cadherin adhesive interactions modulate matrix mechanosensing and fate commitment of mesenchymal stem cells. Nature Materials ... Extracellular matrix, microenvironment, adhesion receptor signaling, mechanotransduction, integrins, cadherins, actin, ...
  http://www.med.upenn.edu/apps/faculty/index.php/g20000220/p13532
*  Mutation Linked to COPD Susceptibility | Medpage Today
Source Reference: Brusselle GG "Matrix metalloproteinase 12, asthma, and COPD" N Engl J Med 2009; DOI: 10.1056/NEJMe0910626. ... Found in the promoter region of matrix metalloproteinase 12 (MMP12), the single-nucleotide polymorphism (SNP) had a positive ... 2009-12-16T17:13:39-0500. *. Primary Source. New England Journal of Medicine. Source Reference: Hunninghake GM, et al "MMP12, ...
  https://www.medpagetoday.com/Pulmonology/SmokingCOPD/17581