Mouse mammary tumor virus - Wikipedia
The majority of mammary tumors in mice are caused by mouse mammary tumor virus. Several mouse strains carry the virus ... Mouse mammary tumor virus (MMTV) is a milk-transmitted retrovirus like the HTL viruses, HI viruses, and BLV. It belongs to the ... "Prolactin regulation of mouse mammary tumor virus (MMTV) expression in normal mouse mammary epithelium". Molecular and Cellular ... "The Mouse Mammary Tumor Virus Transcription Enhancers for Hematopoietic Progenitor and Mammary Gland Cells Share Functional ...
Villanova Digital Library - Construction of Mouse Mammary Tumor Virus Hybrids to Characterize the Sag Gene and Superantigen of...
Construction of Mouse Mammary Tumor Virus Hybrids to Characterize the Sag Gene and Superantigen of Novel Virus Isolates. ... Construction of Mouse Mammary Tumor Virus Hybrids to Characterize the Sag Gene and Superantigen of N... ... Mouse mammary tumor virus.. Superantigens.. About. More Details. Permanent Link. Disclaimers. Disclaimer of Liability. ...
Serval - Mouse mammary tumor virus : the expression of the viral "orf" superantigen in transgenic mice
"Cell transformation and mouse mammary tumor virus. Abstr." by E Y. Lasfargues, J C. Lasfargues et al.
"Chemical carcinogen-mouse mammary tumor virus interactions in cell tra" by D K. Howard, J Schlom et al.
Effect of Withania somnifera root extract on spontaneous estrogen receptor-negative mammary cancer in MMTV/Neu mice
Mice in the treated group (n=35) had an average of 1.66 mammary carcinomas, and mice in the c … ... mice that received a diet containing the extract (750 mg/kg of diet) for 10 months. ... Mammary Neoplasms, Experimental / metabolism * Mammary Neoplasms, Experimental / pathology * Mammary Tumor Virus, Mouse / ... Mice in the treated group (n=35) had an average of 1.66 mammary carcinomas, and mice in the control group (n=33) had 2.48, ...
Inheritance of a mutant histocompatibility gene and a new mammary tumor virus genome in the B6.KH-84 mouse strain<...
Inheritance of a mutant histocompatibility gene and a new mammary tumor virus genome in the B6.KH-84 mouse strain. / Colombo, ... Inheritance of a mutant histocompatibility gene and a new mammary tumor virus genome in the B6.KH-84 mouse strain. ... title = "Inheritance of a mutant histocompatibility gene and a new mammary tumor virus genome in the B6.KH-84 mouse strain", ... Inheritance of a mutant histocompatibility gene and a new mammary tumor virus genome in the B6.KH-84 mouse strain. ...
TagTeam :: Global Down-regulation of Gene Expression Induced by Mouse Mammary Tumor Virus (MMTV) in Normal Mammary Epithelial...
Home Exome pubmed: wnt1 Global Down-regulation of Gene Expression Induced by Mouse Mammary Tumor Virus (MMTV) in Normal Mammary ...
Table 2 - Bovine Leukemia Virus DNA in Human Breast Tissue - Volume 20, Number 5-May 2014 - Emerging Infectious Diseases...
... mouse mammary tumor virus; pAb, polyclonal antibody; HBV, hepatitis B virus; HTLV, human T cell leukemia virus; HPV, human ... Virus. Cells or tissue producing virus (source†). Type of antibody to virus (source†). Reaction of cells or tissue with. ... Bovine Leukemia Virus DNA in Human Breast Tissue Gertrude Case Buehring. , Hua Min Shen, Hanne M. Jensen, K. Yeon Choi1, Dejun ... BLV, bovine leukemia virus; mAb, monoclonal antibody; Ab, antibody; FLK, fetal lamb kidney; MMTV, ...
Breast Cancer Stem Cells | GreenMedInfo | Disease | Natural Medicine
Problem Substances : Mouse Mammary Tumour Viruses (MMTV). [+] Radiotherapy may confer greater aggressiveness to breast cancer ... Pomegranate extract inhibits the proliferation and viability of MMTV-Wnt-1 mouse mammary cancer stem cells in vitro.Sep 30, ... Irradiated breast cancer cells were found to be 30 times more capable of forming new tumors than nonirradiated breast cancer ... study found that morphine contributes to chemoresistance via expanding the population of cancer stem cells and promotes tumor ...
Biological roles of hepatocyte growth factor‑Met signaling from genetically modified animals (Review)
... mouse mammary tumor virus; K14, keratin 14; Pax7, paired box 7; AAV, adeno-associated virus; Emx1, empty spiracles homeobox 1; ... HGF-Tg mice exhibited a range of alterations in the architecture of virgin mouse mammary glands, including an enhancement of ... Mammary gland-specific HGF overexpression. The expressions levels of HGF and Met are regulated during mouse mammary gland ... c-met mice were mated with various Cre recombinase transgenic mice, and conditional c-met KO (Met−/−; cKO) mice have been ...
Modulation of Androgen Receptor Transactivation by Gelsolin | Cancer Research | American Association for Cancer Research
... mouse mammary tumor virus; aa, amino acid; β-gal, β-galactosidase; DAPI, 4,6-diamidino-2-phenylindole; ER, estrogen receptor3b ... Tumor size was measured weekly before harvest. D, LNCaP xenografts in nude mice after castration (b and d) versus sham ... Tumor size was measured weekly before harvest. D, LNCaP xenografts in nude mice after castration (b and d) versus sham ... Onda H., Lueck A., Marks P. W., Warren H. B., Kwiatkowski D. J. Tsc2(+/−) mice develop tumors in multiple sites that express ...
Comparison of Prostate-Specific Promoters and the Use of PSP-Driven Virotherapy for Prostate Cancer
Both mice model with xenograft prostate tumor model and canine model were used. The best PSP was selected to construct a ... conditional oncolytic viruses (such as conditional replication adenovirus (CRAD)) are developed to specifically target prostate ... Although virus-based gene therapy is a promising strategy to combat advanced prostate cancer, its current effectiveness is ... "Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-α: ...
Genome-wide analysis of estrogen receptor binding sites | Nature Genetics
... hormone receptors to octamer transcription factors determines transcriptional synergism at the mouse mammary tumor virus ... Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities. Genes Dev. 9, 2266-2278 (1995). ... Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl. Acad. Sci. ... Lee, C.H., Chinpaisal, C. & Wei, L.N. Cloning and characterization of mouse RIP140, a corepressor for nuclear orphan receptor ...
A New Insight into the Development of Novel Anti-Cancer Drugs that Improve the Expression of Mitochondrial Function-Associated...
ADP-ribosylation of chromosomal proteins and mouse mammary tumor virus gene expression. The Journal of Biological Chemistry. ... In this regard, "cancer is a metabolic disease". This is not only important as an indicator of tumors, but also as one of the ... LACTB is a tumor suppressor that modulates lipid metabolism and cell state. Nature. 2017;. 543. (7647):681-686. ... Chen P, Yu J, Knecht J, Chen Q. Decrease of PDSS2 expression, a novel tumor suppressor, in non-small cell lung cancer. Cancer ...
Publications by Archibald S. Perkins, M.D., Ph.D. - University of Rochester Medical Center
"Acceleration of mouse mammary tumor virus-induced murine mammary tumorigenesis by a p53 172H transgene: influence of FVB ... "Cooperating oncogenic events in murine mammary tumorigenesis: assessment of ErbB2, mutant p53, and mouse mammary tumor virus." ... "Formation of Neu/ErbB2-induced mammary tumors is unaffected by loss of ErbB4." Oncogene.. 2006 Sep 14; 25(41):5664-72. Epub ... "neu/ERBB2 cooperates with p53-172H during mammary tumorigenesis in transgenic mice." Molecular and cellular biology.. 1997 Jun ...
Crystal structure of the nucleosome core particle at 2.8 Å resolution | Learn Science at Scitable
Both types of positioning have been detected with base- pair accuracy in the mouse mammary-tumour virus long terminal repeat 9 ... Pruss, D., Bushmann, F. D. & Wolffe, A. P. Human immunodeficiency virus integrase directs integration to sites of severe DNA ...
Model Details
Strain Summary
Mammary gland tumor - benign. Mammary gland. MMTV - mouse mammary tumor virus. 0.8 ... Mammary gland tumor. Mammary gland. MMTV - mouse mammary tumor virus. 27 - 84 ... Mammary gland adenocarcinoma - type B. Mammary gland. MMTV - mouse mammary tumor virus. very high ... Mammary gland adenocarcinoma - type A. Mammary gland. MMTV - mouse mammary tumor virus. low ...
WHO EMRO | Detection and genotyping of human papillomavirus in breast cancer tissues from Iraqi patients | Volume 20, issue 6 |...
Mouse mammary tumor virus-like sequences in human breast cancer. Cancer Res. 2010 May 1;70(9):3576-85. PMID:20388779 ... Tumour Biol. 2007;28(6):327-32. PMID:18391549. *Lindel K, Forster A, Altermatt HJ, Greiner R, Gruber G. Breast cancer and human ... In the benign tumour group 3/24 (12.5%) revealed positive red signals. None of the healthy breast tissues presented positive ... Kulka J, Kovalszky I, Svastics E, Berta M, Fûle T. Lymphoe-pithelioma-like carcinoma of the breast: not Epstein-Barr virus-, ...
Congenital Hand Deformities: Overview, Incidence, Embryology
The ectoderm in the dorsum of the developing limb bud secretes a protein called wingless-type mouse mammary tumor virus ... The dorsal ectoderm produces wingless-type mouse mammary tumor virus integration site 7a (Wnt-7a), which stimulates production ... The dorsal ectoderm produces wingless-type mouse mammary tumor virus integration site 7a (Wnt-7a), which stimulates production ... The dorsal ectoderm produces wingless-type mouse mammary tumor virus integration site 7a (Wnt-7a), which stimulates production ...
Frontiers | IL-15/IL-15Rα Heterodimeric Complex as Cancer Immunotherapy in Murine Breast Cancer Models
The antitumor efficacy was studied in mouse mammary carcinoma models (Her2/neu transgenic and 4T1-luc mammary cancers) treated ... a moderate tumor growth inhibition or heterogenous tumor regressions with survival improvement. Further studies are warranted ... The antitumor efficacy was studied in mouse mammary carcinoma models (Her2/neu transgenic and 4T1-luc mammary cancers) treated ... Intratumoral GET with plasmid IL-15/IL-15Rα leads to a long-term survival benefit in 4T1 mammary carcinoma model. An ea... ...
CDP/Cutl1 controls differentiation-specific MMTV and cellular gene expression in the mammary gland
Virus expression is low during early stages of mammary development, but high levels of MMTV transcription occur during ... strains of CDP knockout mice increased endogenous MMTV and other mammary-specific cellular genes in undifferentiated mammary ... Virgin mammary glands have high levels of full-length CDP that binds to negative regulatory elements (NRE) to repress MMTV ... Studies with mouse embryo fibroblasts lacking endogenous nuclear CDP confirmed that CDP150 lacks transcriptional repressor or ...
G protein β interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus | Journal of...
... mouse mammary tumor virus; NES, nuclear export signal; RACK1, receptor for activated C-kinase 1; RPLP0, ribosomal ... mouse mammary tumor virus; NES, nuclear export signal; RACK1, receptor for activated C-kinase 1; RPLP0, ribosomal ... and Rack1 on GR-induced transcriptional activity of the glucocorticoid-responsive mouse mammary tumor virus (MMTV) promoter in ... Tumor necrosis factor alpha receptor- and Fas-associated FLASH inhibit transcriptional activity of the glucocorticoid receptor ...
Professor Marysia Placzek | Biosciences | The University of Sheffield
A putative int domain for mouse mammary tumor virus on mouse chromosome 7 is a 5 extension of int-2.. J Virol. , 63(3), 1448- ... and segregation analysis of endogenous proviral units of mouse mammary tumor virus.. J Virol. , 59(3), 535-544. ... Insertion elements and transitions in cloned mouse mammary tumour virus DNA: further delineation of the poison sequences.. ... Peters G, Brookes S, Smith R, Placzek M & Dickson C (1989) The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is ...
Inhibitors of beta-Catenin Signaling
Mammary tumorigenesis in wild mice: identification of a novel int locus in mammary tumors induced by mouse mammary tumor virus ... Many mouse mammary tumor virus-induced tumors contain a provirus integrated into the same region of the host genome. Cell. 1982 ... Dixon S, Smith R, Brooks S, Peters G. Oncogenesis by mouse mammary tumor virus: proviral cellular gene activation in the common ... Roelink H, Wagenaar E, Lopes da Silva S, Nusse R. Wnt-3, a gene activated by provirus injection into mouse mammary tumors, is ...
1dsq.1 | SWISS-MODEL Template Library
CK1ε Is Required for Breast Cancers Dependent on β-Catenin Activity | PLOS ONE
5. Nusse R, Varmus HE (1982) Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same ... Wnt1 was originally discovered as an oncogene activated by mouse mammary tumor virus (MMTV) [5], and mice engineered to express ... 6A), as well as in NIH 3T3 mouse fibroblasts (data not shown). Expression of myristoylated CK1ε is also able to support tumor ... of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice. ...
Precision medicine for human cancers with Notch signaling dysregulation (Review)
... for the mouse mammary tumor virus in mouse mammary tumors identifies a gene whose product has furin-like and thrombospondin- ... Mouse mammary tumor virus infection accelerates mammary carcinogenesis in Wnt-1 transgenic mice by insertional activation of ... are proto-oncogenes that are activated by mouse mammary tumor virus (MMTV) (103-108). Notch signaling is required for the CSL- ... Concerted activation of two potential proto-oncogenes in carcinomas induced by mouse mammary tumour virus. Nature. 320:628-631 ...