RCSB PDB - 4OZV: Crystal Structure of the periplasmic alginate lyase AlgL
Crystal Structure of the periplasmic alginate lyase AlgL ... Alginate lyase. A. 335. Pseudomonas aeruginosa PAO1. Mutation(s ... The majority of genes required for alginate synthesis, including the alginate lyase, algL, are located in a single operon. ... In vitro enzymatic analysis of active site mutants highlights R249 and Y256 as key residues required for alginate lyase ... Crystal Structure of the periplasmic alginate lyase AlgL. *PDB DOI: https://doi.org/10.2210/pdb4OZV/pdb ...
RCSB PDB - 5TDE: TEV Cleaved Human ATP Citrate Lyase Bound to Citrate
TEV Cleaved Human ATP Citrate Lyase Bound to Citrate ... TEV Cleaved Human ATP Citrate Lyase Bound to Citrate. *PDB DOI ... Binding of hydroxycitrate to human ATP-citrate lyase.. Hu, J., Komakula, A., Fraser, M.E.. (2017) Acta Crystallogr D Struct ... Well diffracting crystals showing how the inhibitor binds to human ATP-citrate lyase were grown by modifying the protein. The ... The protein crystallized consisted of residues 2-425-ENLYFQ and S-488-810 of human ATP-citrate lyase. (2S,3S)-2-Hydroxycitrate ...
RCSB PDB - 3C5M: Crystal structure of oligogalacturonate lyase (VPA0088) from Vibrio parahaemolyticus. Northeast Structural...
Crystal structure of oligogalacturonate lyase (VPA0088) from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium ... Crystal structure of oligogalacturonate lyase (VPA0088) from Vibrio parahaemolyticus.. Forouhar, F., Abashidze, M., Seetharaman ... Crystal structure of oligogalacturonate lyase (VPA0088) from Vibrio parahaemolyticus. Northeast Structural Genomics Consortium ...
RCSB PDB - 1RW9: Crystal structure of the Arthrobacter aurescens chondroitin AC lyase
Crystal structure of the Arthrobacter aurescens chondroitin AC lyase ... Chondroitin lyases (EC 4.2.2.4 and EC 4.2.2.5) are glycosaminoglycan-degrading enzymes that act as eliminases. Chondroitin ... Chondroitin lyases (EC 4.2.2.4 and EC 4.2.2.5) are glycosaminoglycan-degrading enzymes that act as eliminases. Chondroitin ... Like other chondroitin AC lyases, it is capable of cleaving hyaluronan. We have determined the three-dimensional crystal ...
RCSB PDB - 1DQU: CRYSTAL STRUCTURE OF THE ISOCITRATE LYASE FROM ASPERGILLUS NIDULANS
CRYSTAL STRUCTURE OF THE ISOCITRATE LYASE FROM ASPERGILLUS NIDULANS ... Isocitrate Lyase from Aspergillus Nidulans: Crystallization and X-ray Analysis of a Glyoxylate Cycle Enzyme.. Langridge, S.J.,& ... Isocitrate lyase catalyses the first committed step of the carbon-conserving glyoxylate bypass, the Mg(2+)-dependent reversible ... Isocitrate lyase catalyses the first committed step of the carbon-conserving glyoxylate bypass, the Mg(2+)-dependent reversible ...
RCSB PDB - 4PFM: SHEWANELLA BENTHICA DHDPS WITH LYSINE AND PYRUVATE
Classification: LYASE. *Organism(s): Shewanella benthica KT99. *Expression System: Escherichia coli. *Mutation(s): No ...
RCSB PDB - 7QGT: Crystal structure of human cystathionine beta-synthase (delta516-525) in complex with AOAA.
Classification: LYASE. *Organism(s): Homo sapiens. *Expression System: Escherichia coli BL21(DE3) ...
RCSB PDB - 2VVA: Human carbonic anhydrase in complex with CO2
Classification: LYASE. *Organism(s): Homo sapiens. *Expression System: Escherichia coli. *Mutation(s): No ...
RCSB PDB - 3QJA: Crystal Structure of the Mycobacterium tuberculosis Indole-3-glycerol phosphate synthase (TrpC) in apo form
Classification: LYASE. *Organism(s): Mycobacterium tuberculosis. *Expression System: Escherichia coli. *Mutation(s): No ...
RCSB PDB - 4QHE: Crystal structure of Mg2+ bound human APE1
DNA-(apurinic or apyrimidinic site) lyase. A. 285. Homo sapiens. Mutation(s): 2 Gene Names: APEX1, APE, APE1, APEX, APX, HAP1, ...
RCSB PDB - 1JCX: Aquifex aeolicus KDO8P synthase in complex with API and Cadmium
Classification: LYASE. *Organism(s): Aquifex aeolicus. *Expression System: Escherichia coli. *Mutation(s): No ...
RCSB PDB - 5HST: Crystal structure of the dehydratase domain of MlnB from Bacillus amyloliquefaciens
Classification: LYASE. *Organism(s): Bacillus amyloliquefaciens. *Expression System: Escherichia coli BL21(DE3) ...
RCSB PDB - 1EPX: CRYSTAL STRUCTURE ANALYSIS OF ALDOLASE FROM L. MEXICANA
Classification: LYASE. *Organism(s): Leishmania mexicana. *Expression System: Escherichia coli. *Mutation(s): No ...
RCSB PDB - 5HVN: 3.0 Angstrom Crystal Structure of 3-dehydroquinate Synthase (AroB) from Francisella tularensis in Complex with...
Classification: LYASE. *Organism(s): Francisella tularensis subsp. tularensis SCHU S4. *Expression System: Escherichia coli ...
RCSB PDB - 3EWZ: human orotidyl-5'-monophosphate decarboxylase in complex with 5-cyano-UMP
Classification: LYASE. *Organism(s): Homo sapiens. *Expression System: Escherichia coli. *Mutation(s): No ...
RCSB PDB - 2QCE: Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to...
Classification: LYASE. *Organism(s): Homo sapiens. *Expression System: Escherichia coli. *Mutation(s): No ...
RCSB PDB - 7ETD: Crystal structure of AbHpaI-Zn-(4S)-KDGlu complex, Class II aldolase, HpaI from Acinetobacter baumannii
Classification: LYASE. *Organism(s): Acinetobacter baumannii. *Expression System: Escherichia coli BL21(DE3) ...
RCSB PDB - 4OYM: Human solAC Complexed with (4-Amino-furazan-3-yl)-(3-methoxy-phenyl)-methanone
Classification: LYASE. *Organism(s): Homo sapiens. *Expression System: Spodoptera frugiperda. *Mutation(s): Yes ...
RCSB PDB - 6PVX: RNase A in complex with p5U
Classification: LYASE. *Organism(s): Bos taurus. *Mutation(s): No *Deposited: 2019-07-21 Released: 2019-11-06 ...
RCSB PDB - 1HKV: mycobacterium diaminopimelate dicarboxylase (lysa)
Classification: LYASE. *Organism(s): Mycobacterium tuberculosis H37Rv. *Expression System: Escherichia coli. *Mutation(s): No ...
RCSB PDB - 3NNT: Crystal Structure of K170M Mutant of Type I 3-Dehydroquinate Dehydratase (aroD) from Salmonella typhimurium...
Classification: LYASE. *Organism(s): Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 ...
RCSB PDB - 3M98: Crystal structure of human carbonic anhydrase isozyme II with 5-(1H-benzimidazol-1-ylacetyl)-2...
Classification: LYASE. *Organism(s): Homo sapiens. *Expression System: Escherichia coli. *Mutation(s): No ...
RCSB PDB - 4LU3: The crystal structure of the human carbonic anhydrase XIV
Classification: Lyase/lyase Inhibitor. *Organism(s): Homo sapiens. *Expression System: Spodoptera frugiperda ...
RCSB PDB - 4E49: Nucleophile recognition as an alternative inhibition mode for benzoic acid based carbonic anhydrase inhibitors
Classification: LYASE/LYASE INHIBITOR. *Organism(s): Homo sapiens. *Expression System: Escherichia coli ...
RCSB PDB - 6I0L: Crystal structure of human carbonic anhydrase I in complex with the 1-[4-chloro-3-(trifluoromethyl)phenyl]-3-...
Classification: LYASE. *Organism(s): Homo sapiens. *Mutation(s): No *Deposited: 2018-10-26 Released: 2019-11-20 ...
RCSB PDB - 4LBH: 5-chloro-2-hydroxyhydroquinone dehydrochlorinase (TftG) from Burkholderia phenoliruptrix AC1100: Apo-form
... which we propose to be lyases. ...
RCSB PDB - 1DUB: 2-ENOYL-COA HYDRATASE, DATA COLLECTED AT 100 K, PH 6.5
Classification: LYASE. *Organism(s): Rattus norvegicus. *Mutation(s): No *Deposited: 1996-06-10 Released: 1997-07-07 ...
RCSB PDB - 1YDN: Crystal Structure of the HMG-CoA Lyase from Brucella melitensis, Northeast Structural Genomics Target LR35.
Crystal Structure of the HMG-CoA Lyase from Brucella melitensis, Northeast Structural Genomics Target LR35. ... HYDROXYMETHYLGLUTARYL-COA LYASE. A, B, C, D. 295. Brucella melitensis bv. 1 str. 16M. Mutation(s): 6 Gene Names: GeneID:1197637 ... Here we present crystal structures of the HMG-CoA lyases from Bacillus subtilis and Brucella melitensis at 2.7 and 2.3 A ... We propose a detailed model for the catalytic reaction mechanism of HMG-CoA lyase based on the examination of previously ...
RCSB PDB - P0T Ligand Summary Page
Steroid 17-alpha-hydroxylase/17,20 lyase. MWELVALLLLTLAYLFWPKRRCPGAKYPKSLLSLPLVGSLPFLPRHGHMH.... unknown. inhibitor. 3-hydroxy- ...
RCSB PDB - 3LYE: Crystal structure of oxaloacetate acetylhydrolase
Oxalacetate is the main OAH substrate, but the enzyme also acts as a lyase of (2R,3S)-dimethyl malate with approximately 1000- ... Comparison between the OAH structure and that of the closely related enzyme, 2,3-dimethylmalate lyase, suggests potential ... Oxalacetate acetylhydrolase (OAH), a member of the phosphoenolpyruvate mutase/isocitrate lyase superfamily, catalyzes the ...