*  Adipose Tissue Lipolysis Is Upregulated in Lean and Obese Men During Acute Resistance Exercise | Diabetes Care
Although it can be estimated that only a small fraction of the fatty acids released by lipolysis can actually be oxidized, our ... Lipolysis was apparently stimulated by the progressive rise in catecholamines during resistance exercise. The increase in TGLA ... Quisth V, Enoksson S, Blaak E, Hagstrom-Toft E, Arner P, Bolinder J: Major differences in noradrenaline action on lipolysis and ... Adipose Tissue Lipolysis Is Upregulated in Lean and Obese Men During Acute Resistance Exercise. ...
http://care.diabetesjournals.org/content/31/7/1397
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Danadian K, Lewy V, Janovsky JJ, Arslanian S: Lipolysis in African-American children: is it a metabolic risk factor ... African Americans have lower rates of basal lipolysis than whites (37). This could be a metabolic risk factor for both the ...
http://care.diabetesjournals.org/content/31/11/2211
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Lipolysis of VLDL-derived fatty acid then can be thought of as an important process for activation of PPARα both in the liver ... Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue. J Clin Invest 2010;120:3466-3479. ... Local VLDL lipolysis may present high concentrations of fatty acid to tissues. Supporting this hypothesis, treatment with P-407 ... those with high liver fat manifested less suppression of hepatic glucose production and lipolysis at a lower insulin dose and ...
http://care.diabetesjournals.org/content/34/9/e140
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One of the most important metabolic actions of insulin is to prevent lipolysis (23). In the present study, the duration of the ... Plasma concentrations of substrates indicating primarily lipolysis (FFA and glycerol) and ketogenesis (β-hydroxybutyrate) were ... mechanisms contribute to the late phase of hypoglycaemic glucose counterregulation in humans by stimulating lipolysis. J Clin ...
http://care.diabetesjournals.org/content/30/10/2447
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Phlorizin induces lipolysis and alters meal patterns in both early- and late-lactation dairy cows. J Dairy Sci 90: 1810- 1815, ... Veterinary literature suggests that chronic administration of phlorizin in lactating cows induces lipolysis (22), and ...
http://care.diabetesjournals.org/content/32/4/650
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Striking effects on hepatic glucose production, de novo lipogenesis, lipolysis, and whole-body fuel selection. J Clin Invest ...
http://care.diabetesjournals.org/content/35/1/137
*  Dietary Fat Acutely Increases Glucose Concentrations and Insulin Requirements in Patients With Type 1 Diabetes | Diabetes Care
Causal linkage between insulin suppression of lipolysis and suppression of liver glucose output in dogs. J Clin Invest 1996;98: ...
http://care.diabetesjournals.org/content/36/4/810.full
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Butyrate and other short-chain fatty acids increase the rate of lipolysis in 3T3-L1 adipocytes. PeerJ 2014;2:e611pmid:25320679 ... increase circulating glucose and lipids due to increased lipolysis, hepatic glucose production, and dietary (chylomicron- ...
http://care.diabetesjournals.org/content/38/8/1402
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Bicarbonate use in DKA remains controversial (28). At a pH ,7.0, reestablishing insulin activity blocks lipolysis and resolves ... to prevent lipolysis and subsequent ketogenesis, although the evidence for this is weak (14). Both DKA and HHS are associated ... lipolysis) and to unrestrained hepatic fatty acid oxidation to ketone bodies (β-hydroxybutyrate [β-OHB] and acetoacetate), with ...
http://care.diabetesjournals.org/content/24/1/154
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1,120 ± 344 ng/L/h, P = 0.027) and lipolysis (free fatty acid AUC0-24h 7.5 ± 1.6 vs. 8.9 ± 1.9 mmol/L/h, P = 0.005; β-OH- ... Morning and evening glargine administration had differential effects on 24-h lipolysis and plasma glucagon concentrations. The ... However, with evening glargine administration, the suppression of nocturnal EGP, lipolysis, and glucagon concentration are more ... the latter was more effective in suppressing overall lipolysis and plasma glucagon concentrations, primarily over the last 12 h ...
http://care.diabetesjournals.org/content/38/3/503
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NPFF decreases lipolysis in human fat cells in a dose-dependent fashion and may be as potent as insulin, appearing to act by ... Genetic variants in lipolysis have been documented, with a group of 311 obese and 223 nonobese women and 114 and 82 such men, ... A common haplotype in the G-protein-coupled receptor gene GPR74 is associated with leanness and increased lipolysis. Am J Hum ... obesity was associated with increased insulin-induced inhibition of lipolysis and decreased norepinephrine-induced lipolysis. ...
http://care.diabetesjournals.org/content/32/5/e48
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This is consistent with previous observations that reduced apoC-III in TRL enhances LPL-mediated lipolysis and receptor- ... dissociation of apolipoprotein C during lipoprotein lipase induced lipolysis. Biochim Biophys Acta 486:23-35, 1976. ...
http://care.diabetesjournals.org/content/31/8/1656
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Bicarbonate use in DKA remains controversial (58). At a pH ,7.0, administration of insulin blocks lipolysis and resolves ... to prevent lipolysis and subsequent ketogenesis (15). Both DKA and HHS are associated with glycosuria, leading to osmotic ... lipolysis) and to unrestrained hepatic fatty acid oxidation to ketone bodies (β-hydroxybutyrate ([β-OHB] and acetoacetate), ...
http://care.diabetesjournals.org/content/29/12/2739
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The lowering of FFAs and triglycerides, indicating the ease of lipolysis, might also contribute to the improvement of β-cell ... continuous decline in β-cell function is affected by glucotoxicity generated by hyperglycemia and lipotoxicity due to lipolysis ...
http://care.diabetesjournals.org/content/27/11/2597
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Lipolysis and ketogenesis leading to diabetic ketoacidosis (DKA) may be suppressed by the continuous provision of small doses ...
http://care.diabetesjournals.org/content/33/5/1031
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A crucial question remains as to what regulatory molecules contribute to the change from lipid storage to accelerated lipolysis ... Thus, like a perfect storm, subclinical inflammation, placental hormones, reduced adiponectin secretion, and excess lipolysis ... The ability of insulin to suppress whole-body lipolysis is also reduced during late pregnancy (3), and this is further reduced ... thus accelerating adipose tissue insulin resistance and the switch from lipid storage to lipolysis. This transition to insulin ...
http://care.diabetesjournals.org/content/30/Supplement_2/S112
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When larger VLDL1 is produced, lipolysis by LPL is less efficient, leading to production of remnant particles, which are ... with lipolysis by lipoprotein lipase (LPL) to form LDL1. Under more typical circumstances of triglyceride formation, VLDL2 is ... Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an antiinflammatory role for lipoprotein ... models describe a pathway from VLDL formation in the liver to formation of IDL and then of LDL particles via lipolysis. ...
http://care.diabetesjournals.org/content/30/8/2164
*  Spectrum of Liver Disease in Type 2 Diabetes and Management of Patients With Diabetes and Liver Disease | Diabetes Care
The pathogenic sequence of events leading to hepatocellular carcinoma appears to be insulin resistance, increased lipolysis, ... This paradoxical effect is thought to be due to an increase in circulating free fatty acids due to increased lipolysis seen ... A central abnormality in the pathogenesis of steatosis appears to be insulin resistance resulting in lipolysis, which increases ...
http://care.diabetesjournals.org/content/30/3/734.full
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... lipolysis) and to unrestrained hepatic fatty acid oxidation in the liver to ketone bodies (β-hydroxybutyrate and acetoacetate ... adequate to prevent excessive lipolysis and subsequent ketogenesis but not hyperglycemia (4). ... levels in HHS are inadequate to facilitate glucose utilization by insulin-sensitive tissues but adequate to prevent lipolysis ...
http://care.diabetesjournals.org/content/32/7/1335
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... inhibition of lipolysis, and energy storage leading to weight gain (34). High-glycemic load diets also lead to other ...
http://care.diabetesjournals.org/content/28/12/2939
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... lipolysis, and hepatic and skeletal muscle triglyceride content in patients with type 2 diabetes. Diabetes 51:797-802, 2002. ... including lipolysis (19). Further triglyceride enrichment of the lipolytic products through the action of cholesteryl ester ... a protein that reduces lipolysis of triglyceride-rich lipoproteins and clearance of their remnants (59). Fibrates also raise ...
http://care.diabetesjournals.org/content/27/6/1496
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... and further to IDL during lipolysis of VLDL. Reduced conversion of squalene to desmosterol might increase its serum level in ...
http://care.diabetesjournals.org/content/27/1/53
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CONCLUSIONS Despite better suppression of lipolysis and less suppression of endogenous insulin secretion by nocturnal than ...
http://care.diabetesjournals.org/content/17/8/805
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... beta-hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G. J Biol Chem 280:26649-26652, 2005. ... Lipolysis of triglyceride-rich lipoproteins generates PPAR ligands: evidence for an anti-inflammatory role for lipoprotein ... which is allowing understanding of the mechanism of action of this agent in inhibiting adipocyte lipolysis in vivo, and ... may explain the action of high-protein ketogenic diets in inhibiting lipolysis and decreasing hepatic triglyceride synthesis. ...
http://care.diabetesjournals.org/content/28/10/2577
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... with local lipolysis bringing about fatty acid-mediated inhibition of β-cell function (22). Exposure to even modest ... Local lipolysis will bring about interstitial and intracellular concentrations of fatty acids sufficient to inhibit β-cell ...
http://care.diabetesjournals.org/content/39/5/808