Leukotriene D4 - Wikipedia
Leukotriene D4 (LTD4) is one of the leukotrienes. Its main function in the body is to induce the contraction of smooth muscle, ... Other leukotrienes that function in a similar manner are leukotrienes C4 and E4. Pharmacological agents that inhibit the ... function of these leukotrienes are leukotriene receptor antagonists (e.g., zafirlukast, montelukast) and are useful for ...
The effect of leukotriene C4 and D4 on cutaneous blood flow in humans
Mechanism of Action of Leukotriene D4 on Guinea Pig Tracheal Smooth Muscle Cells: Roles of Ca++ Influx and Intracellular Ca++...
Mechanism of Action of Leukotriene D4 on Guinea Pig Tracheal Smooth Muscle Cells: Roles of Ca++ Influx and Intracellular Ca++ ... OtherPROSTAGLANDINS, LEUKOTRIENES AND OTHER EICOSANOIDS. Mechanism of Action of Leukotriene D4 on Guinea Pig Tracheal Smooth ... OtherPROSTAGLANDINS, LEUKOTRIENES AND OTHER EICOSANOIDS. Mechanism of Action of Leukotriene D4 on Guinea Pig Tracheal Smooth ... Biosynthesis of Sulfidopeptide Leukotrienes Via the Transfer of Leukotriene A4 from Polymorphonuclear Cells to Bovine Retinal ...
Binding of radiolabeled high affinity antagonist to leukotriene D4 receptor in guinea pig lung membranes: interconversion of...
Binding of radiolabeled high affinity antagonist to leukotriene D4 receptor in guinea pig lung membranes: interconversion of ... The kinetic parameters and the pharmacological specificity of a high affinity leukotriene D4 (LTD4) receptor antagonist, ICI- ... Binding of radiolabeled high affinity antagonist to leukotriene D4 receptor in guinea pig lung membranes: interconversion of ... Binding of radiolabeled high affinity antagonist to leukotriene D4 receptor in guinea pig lung membranes: interconversion of ...
AID 54896 - Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung membrane - PubChem
Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung membrane. ...
EFFECTS OF LEUKOTRIENE-D4 AND ITS SPECIFIC ANTAGONIST L-660, 711 IN ISOLATED RAT-HEART WITH CHRONIC MYOCARDIAL-INFARCTION -...
Expanding roles for leukotrienes in airway inflammation | SpringerLink
Cysteinyl (cys) LTs C4, D4, and E4 are long ... Leukotrienes (LTs) are lipid mediators derived from the 5- ... Leukotriene D4 induces gene expression in human monocytes through cysteinyl leukotriene type I receptor. J Allergy Clin Immunol ... Kato J, Kohyama T, Okazaki H, et al.: Leukotriene D4 potentiates fibronectin-induced migration of human lung fibroblasts. Clin ... Lamoureux J, Stankova J, Rola-Pleszczynski M: Leukotriene D4 enhances immunoglobulin production in CD40-activated human B ...
Immediate Hypersensitivity Reactions Medication: Vasopressors, Bronchodilators, Corticosteroids, Histamine 1 receptor...
Inhibits bronchoconstriction as competitive receptor antagonist of leukotrienes D4 & E4; receptor occupation and cysteinyl ... A selective and competitive inhibitor of the cysteinyl leukotriene receptor. Cysteinyl leukotrienes and leukotriene receptor ... Leukotriene inhibitors. Class Summary. Leukotrienes are synthesized by degranulated mast cells and basophils and contribute to ... Inhibitor of 5-lipoxygenase, which inhibits formation of leukotrienes (LTB4, LTC4, LTD4, & LTE4). Inhibition of leukotriene ...
sulfur compound catabolic process - Ontology Report - Rat Genome Database
Metabolomics in COPD | Archivos de Bronconeumología
Leukotriene D4 [LTD4] (sp ↑)37 Leukotriene E4 [LTE4] (sp↑)37 Thromboxane D2 [11-dehydro-TBX2] (sp ↑) 37 ... leukotrienes, and thromboxanes), have shown significantly higher levels in the sputum of COPD patients compared to controls.37 ... along with a decrease in lipooxygenase that transforms fatty acids into leukotrienes.31 ...
Frontiers | Roles, Actions, and Therapeutic Potential of Specialized Pro-resolving Lipid Mediators for the Treatment of...
1990). Identification of lipoxin A4 and its relationship to the sulfidopeptide leukotrienes C4, D4, and E4 in the ... New maresin conjugates in tissue regeneration pathway counters leukotriene D4-stimulated vascular responses. FASEB J. 32, 4043- ... Selectivity of recombinant human leukotriene D(4), leukotriene B(4), and lipoxin A(4) receptors with aspirin-triggered 15-epi- ... 2014). Reduced 15-lipoxygenase 2 and lipoxin A4/leukotriene B4 ratio in children with cystic fibrosis. Eur. Respir. J. 44, 394- ...
Zafirlukast - Mechanism, Indication, Contraindications, Dosing, Adverse Effect, Interaction, Renal Dose, Hepatic Dose | Drug...
Singulair (montelukast) dosing, indications, interactions, adverse effects, and more
Internet Scientific Publications
... leukotrienes C4, D4, and E4). Compelling evidence exists for the role of the cysteinyl leukotrienes in the pathophysiology of ... 5. Wardlaw AJ, Hay H, Cromwell O, et al.: Leukotrienes, LTC4 and LTB4 in bronchoalveolar lavage in bronchial asthma and other ... 4. Weller PF, Lee CW, Foster DW, et al.: Generation and metabolism of 5-1ipoxygenase pathway leukotrienes by human eosinophils ... EPA is a substrate for the generation of less active prostanoids and leukotrienes than arachidonic acid, thereby potentially ...
Thieme E-Journals - Pneumologie / Abstract
7 Diamant Z, Hiltermann J T, Van Rensen E L. The effect of inhaled leukotriene D4 and metacholine on sputum cell differentials ... 27 Pearlman D S, Ostrom N K, Bronsky E A, Bonuccelli C M, Hanby L A. The leukotriene D4-receptor antagonist zafirlukast ... a leukotriene D4 receptor antagonist, in subjects with bronchial asthma. Am J Respir Crit Care Med. 1994; 150 618-623 ... a potent leukotriene D4-receptor antagonist. N Engl J Med. 1990; 232 1736-1739 ...
N-3 polyunsaturated fatty acids and mast cell activation - NRC Publications Archive - Canada.ca
Pathoma - Respiratory Pathology Flashcards by Jon L | Brainscape
Ertapenem: Uses, Interactions, Mechanism of Action | DrugBank Online
Zafirlukast-13C,d6 (ICI 204219-13C,d6) | Stable Isotope | MedChemExpress
Zafirlukast (ICI 204219) is a potent orally active leukotriene D4 (LTD4) receptor antagonist. Zafirlukast shows anti-asthmatic ... Zafirlukast (ICI 204219) is a potent orally active leukotriene D4 (LTD4) receptor antagonist. Zafirlukast shows anti-asthmatic ... Zafirlukast (ICI 204219) is a potent orally active leukotriene D4 (LTD4) receptor antagonist. Zafirlukast shows anti-asthmatic ... Role of leukotrienes in exercise-induced asthma. Inhibitory effect of ICI 204219, a potent leukotriene D4 receptor antagonist. ...
R. Kirk Riemer's Profile | Stanford Profiles
LEUKOTRIENE-C4, LEUKOTRIENE-D4, AND LEUKOTRIENE-E4 IN FETAL LAMB TRACHEAL FLUID JOURNAL OF DEVELOPMENTAL PHYSIOLOGY Velvis, H ... To further investigate the role of leukotrienes, we measured concentrations of leukotriene (LT) C4, LTD4, and LTE4 in 17 ... During normoxia (descending aortic PaO2 2.9 +/- 0.3 kPa [21.5 +/- 2.5 mmHg]; mean +/- SD), all 3 leukotrienes were detected in ... Purification and separation of leukotrienes was done by reverse-phase high performance liquid chromatography using a gradient ...
Dehydropeptidase 1 promotes metastasis through regulation of E-cadherin expression in colon cancer | Oncotarget
Polypodium leucotomos as an Adjunct Treatment of Pigmentary Disorders | JCAD | The Journal of Clinical and Aesthetic Dermatology
Page 1 | Search Results | Anesthesiology | American Society of Anesthesiologists
leukotriene d4 (1) * lung (1) * venous oxygen saturation (1) * volume (1) * wounds and injuries (1) ... CARDIOPULMONARY INJURY PRODUCED BY LEUKOTRIENE D 4 IN ANESTHETIZED DOGS J. M. Shapiro, M.D., F. G. Mihm, M.D., B. D. Halperin, ...
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Cysteinyl leukotriene metabolism of human eosinophils in allergic disease<...
... eosinophilic rhinosinusitis present a characteristic fatty acid metabolism with selectively higher production of leukotriene D4 ... Cysteinyl leukotriene metabolism of human eosinophils in allergic disease」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。 ... Cysteinyl leukotriene metabolism of human eosinophils in allergic disease. Jun Miyata, Koichi Fukunaga, Yusuke Kawashima, Osamu ... Cysteinyl leukotriene metabolism of human eosinophils in
Wondossen Sime - Lund University
A new approach: Animal and clinical pharmacology of zafirlukast (Accolate®, ICI-204,219)<...
Orally administered zafirlukast decreases the bronchoconstrictor effect of inhaled leukotriene D4 (LTD4) in a dose-dependent ... Orally administered zafirlukast decreases the bronchoconstrictor effect of inhaled leukotriene D4 (LTD4) in a dose-dependent ... Orally administered zafirlukast decreases the bronchoconstrictor effect of inhaled leukotriene D4 (LTD4) in a dose-dependent ... Orally administered zafirlukast decreases the bronchoconstrictor effect of inhaled leukotriene D4 (LTD4) in a dose-dependent ...
CHEMICAL MEDIATORS OF INFLAMMATION - Welcome | University of - [PDF Document]
Leukotrienes C4, D4, E4. 103 X histamine potency. Antiinflammatory. Page 20. LYSOSOMAL CONSTITUENTS ...