Intravenous Ribavirin Treatment for Severe Adenovirus Disease in Immunocompromised Children | ELECTRONIC ARTICLE | Pediatrics
Cidofovir, a cytosine nucleotide analog, has shown apparent efficacy in eradicating both adenovirus infection and treating symptomatic disease in a number of immunocompromised patients, including children.23,25-31 In a series of 22 SCT patients (age range: 1-19 years) with asymptomatic adenoviral infection or disease: 2 of 3 patients treated with cidofovir (both of whom had asymptomatic infection) recovered in contrast to 3 of 13 patients (2 asymptomatic infection and 1 probable disease) treated with ribavirin.25 However, the toxicity profile of cidofovir, most notably nephrotoxicity, has limited its use. Reports of success with alternative strategies are less common and include an apparent beneficial effect of: donor leukocyte infusion in BMT recipients25,32; intravenous immunoglobulin (IVGG) in a child with SCID and adenovirus pneumonia33 and IV ganciclovir in an adult OHT recipient with adenovirus pneumonia.34 None of our patients received leukocyte ...http://pediatrics.aappublications.org/content/110/1/e9.full
Caspofungin Acetate, Fluconazole, or Voriconazole in Preventing Fungal Infections in Patients Following Donor Stem Cell...
RATIONALE: Caspofungin acetate, fluconazole, and voriconazole may be effective in preventing fungal infections in patients following donor stem cell trahttp://www.knowcancer.com/cancer-trials/NCT01503515/
Increased apoptosis of immunoreactive host cells and augmented donor leukocyte chimerism, not sustained inhibition of B7...
Lu, L and Li, W and Zhong, C and Qian, S and Fung, JJ and Thomson, AW and Starzl, TE (1999) Increased apoptosis of immunoreactive host cells and augmented donor leukocyte chimerism, not sustained inhibition of B7 molecule expression are associated with prolonged cardiac allograft survival in mice preconditioned with immature donor dendritic cells plus anti-CD40L mAb. Transplantation, 68 (6). 747 - 757. ISSN 0041-1337 ...http://d-scholarship.pitt.edu/5476/
Augmentation with bone marrow of donor leukocyte migration for kidney, liver, heart, and pancreas islet transplantation - D...
Fontes, P and Rao, A and Demetris, AJ and Zeevi, A and Trucco, M and Carroll, P and Rybka, W and Ricordi, C and Dodson, F and Shapiro, R and Tzakis, A and Todo, S and Abu-Elmagd, K and Jordan, M and Fung, JJ and Starzl, TE (1994) Augmentation with bone marrow of donor leukocyte migration for kidney, liver, heart, and pancreas islet transplantation. Lancet, 344. 151 - 155. ISSN 0140-6736 ...http://d-scholarship.pitt.edu/5023/
Safety and Effectiveness of Granulocyte Transfusions in Resolving Infection in People With Neutropenia (The RING Study) - Full...
Thousands of people each year are hospitalized for neutropenia, which continues to cause substantial morbidity and mortality for those affected. Neutropenia is primarily caused by chemotherapy and various other cancer treatments, such as radiation therapy, biotherapy, and HSC transplantation. Signs and symptoms of neutropenia may include high fever, chills, sore throat, and diarrhea. In neutropenia, the number of neutrophils, a type of granulocyte, is greatly reduced, weakening the body's immune system and increasing the risk of infection. Therefore, a method to provide adequate numbers of functional granulocytes to people with neutropenia could be of greatest benefit for recovery. Administration of a combination of two drugs, granulocyte colony-stimulating factor (G-CSF) and dexamethasone, has been show to stimulate the body to produce a large number of granulocytes. Granulocyte transfusions obtained from donors who have received these two drugs may help people with low white blood cell ...https://clinicaltrials.gov/ct2/show/NCT00627393?term=Blood+Transfusion&recr=Open&fund=01&rank=3
JCI - Donor dendritic cell-derived exosomes promote allograft-targeting immune response
After organ transplantation, donor cDCs migrate to the recipient lymphoid tissues and prime directly alloreactive T cells (1, 2). However, we found that after heterotopic (abdomen) cardiac transplantation in mice, donor DCs are detected in the spleen and graft-draining lymph nodes in low numbers, likely because, as shown before, they have short lifespan and are targets of NK cells and cytotoxic T cells (8-11). Besides, the transplanted heart contains a limited number of tissue-resident DCs - ranging between 11 × 104 and 44 × 104 per heart (24) - from which a reduced percentage home in recipient lymphoid tissues. Indeed, we found that, at its peak, only 1,127 ± 372 donor cells (mostly migrating DCs) reach the recipient spleen. This figure represents the average number of donor leukocytes at a given time, since donor leukocytes are constantly arriving and becoming apoptotic within the spleen. Beyond this potential caveat, and considering that the mouse spleen harbors ...https://m.jci.org/articles/view/84577
Granulocyte Transfusion | Annals of Internal Medicine | American College of Physicians
To the editor: In a recent article Winston and colleagues (1) describe their study as a "prospectively randomized, controlled study." Several of their points seem to need additional comments. First, with regard to the patient characteristics, why were the numbers of patients in the treatment and control groups with acute myelogenous (p =0.18) and acute lymphocytic leukemia (p =0.01) so different? What would be the effect of removing the patients with acute lymphocytic leukemia from the analysis? Did the fact that one group had more acute lymphocytic leukemia patients give that group a response advantage or disadvantage? These questions also ...http://annals.org/aim/article/696218/granulocyte-transfusion
北京大学医学部机构知识库(IR@PKUHSC): Treating donor mice with rhIL-11 and rhG-CSF promotes transplant-tolerance and preserves the effects...
We investigated the impact of recombinant human interleukin-11 (rhIL-11) and granulocyte colony-stimulating factor (rhG-CSF) on bone marrow transplantation. Treatments for leukemic mice were (A) no treatment, (B) mock transplantation, and transplantation from the following donors: (C1) syngeneic, (C) controls, (D) rhG-CSF treated, (E) rhIL-11 treated, and (F) rhIL-11 and rhG-CSF treated. Graft-versus-host disease incidences were 100%, 60%, 78%, and 30% in C, D, E, and F, respectively. The 30 d leukemia-free survival improved significantly in F (70%) compared to C (0%), D (40%), and E (20%) (P < 0.01). Thus, treating donor mice with rhIL-11 and rhG-CSF promoted transplant-tolerance and recipient survival. (C) 2008 Elsevier Ltd. All rights reserved. ...http://ir.bjmu.edu.cn/handle/400002259/55313
Market Design: 2016
Organ donation should neither enrich nor impose financial burdens on donors. We describe the scope of health care required for all living kidney donors that reflects contemporary understanding of long-term donor health outcomes, propose an approach to identify donor health conditions which should be covered within the framework of financial neutrality, and propose strategies to pay for this care. Despite the Affordable Care Act in the United States, donors continue to have inadequate coverage for important health conditions that are either donation related or may compromise post-donation kidney function. Amendment of Medicare regulations is needed to clarify that surveillance and treatment of conditions that may compromise post-donation kidney function following donor nephrectomy will be covered without expense to the donor. In other countries lacking health insurance for all residents, sufficient data exist to allow creation of a compensation fund or donor insurance policies to ensure ...http://marketdesigner.blogspot.tw/2016/
Disaster Risk Financing and Insurance Program
DONORS. Donors support the Disaster Risk Financing and Insurance (DRFI) program in its work to help vulnerable countries improve financial resilience against climate and disaster risk. DRFI is grateful to the following donors and partners who make its work possible:. Government of Switzerland - Swiss State Secretariat for Economic Affairs. The Swiss State Secretariat for Economic Affairs SECO is a major supporter of DRFI. The Sovereign Disaster Risk Financing and Insurance Program for Middle-Income Countries is a partnership between the World Bank and SECO that aims to reduce the financial vulnerability of these states to natural disasters. This program helps middle-income country governments improve their financial response capacity in the aftermath of a natural disaster while protecting their long-term fiscal balances.. Government of Japan. The Government of Japan is an active supporter of DRFI. The Pacific Disaster Risk Financing and Insurance Program is supported by the Government of Japan ...http://www.worldbank.org/en/programs/disaster-risk-financing-and-insurance-program
Transfusions of white blood cells to treat infections in people with low white blood cell counts or white blood cells that do...
We evaluated the evidence about whether white blood cell transfusions (also called granulocyte transfusions) given to treat infections are safe and reduce the risk of death or severe outcomes due to infection. Our target population was people with a very low white count (neutropenia) or white cells that did not function properly (neutrophil dysfunction).https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0013409/
Medical Complications in Cancer Patients. | Annals of Internal Medicine | American College of Physicians
Medical complications from the neoplasm itself, or its treatment by present-day multimodal therapy, are the subjects of the 18 essays by an international group of experts evenly selected from both sides of the Atlantic. This is a laudable critical evaluation of many types of therapeutic protocols, as exemplified by Klastersky's chapter, "Prevention and Therapy of Infection in Myelo-suppressed Patients." There are excellent reviews also of cardiac and renal diseases associated with all types of cancer, neurologic disorders, respiratory complications, nutrition, coagulopathies, ectopic hormone production, and hypercalcemia. The indications for platelet and granulocyte transfusion are reviewed, as are the pros and ...http://annals.org/aim/article/694887/medical-complications-cancer-patients
Current data on granulocytes donations]. - MyScienceWork
[Current data on granulocytes donations].: Granulocyte transfusion is uncommon but essential for some aplastic patients with major infection and those with septhttps://www.mysciencework.com/publication/show/current-data-granulocytes-donations-94e7d3ea
Oxygen and Transfusion Therapy in York, PA | VCA Charles E. London Animal Hospital
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Oxygen and Transfusion Therapy in Surprise, AZ | VCA El Mirage Animal Hospital
Get exceptional Oxygen and Transfusion Therapy services from highly experienced & loving pet care professionals in Surprise, AZ. Visit VCA El Mirage Animal Hospital today.https://vcahospitals.com/el-mirage/services/primary-care/oxygen-and-transfusion-therapy
SELL monoclonal antibody, clone DREG56 (FITC) - (MAB9801) - Products - Abnova
Mouse monoclonal antibody raised against native SELL. Native purified SELL from PMA-activated human peripheral blood leukocytes. (MAB9801) - Products - Abnovahttp://www.abnova.com/products/products_detail.asp?catalog_id=MAB9801
18 Dental Surgeon (Class-II) posts in Health Department, Haryana, < 19.8.2014 | Big...
d) Relaxation in upper age limit is available to physically handicapped candidates of Haryana upto 10 years for the Schedule Castes/Backward Castes candidates and upto 5 years for General ...http://www.big-jobs.in/2014/08/18-dental-surgeon-class-ii-posts-in.html
Treatment of Patients With MDS or AML With an Impending Hematological Relapse With Azacitidine (Vidaza) - AdisInsight
This trial will investigate the efficacy and safety of azacitidine [Vidaza] for the prevention of haematological relapse in patients with acute myeloidhttp://adisinsight.springer.com/trials/700209050
Gentaur Molecular :SibEm \ Mnl I \ E482
Gentaur molecular products has all kinds of products like :search , SibEm \ Mnl I \ E482 for more molecular products just contact ushttp://www.antibody-antibodies.com/product_det.php?id=291700&supplier=search&name=Mnl%20I
Leadtek GeForce GTX 260 Extreme+ 216 Shaders | TechPowerUp Forums
The new Leadtek GeForce GTX 260 Extreme+ comes with an increased shader count of 216 compared to 196 on the regular GTX 260. Leadtek has also overclocked...https://www.techpowerup.com/forums/threads/leadtek-geforce-gtx-260-extreme-216-shaders.75181/
Ear Spirals & Ear Hanger Plugs From 14 Gauge up to 5/8'
Shop for ear spirals, hangers and pinchers. Available in wood, stone, glass, and stainless steel. Sizes / gauges 14g, 12g, 10g, 8g, 6g, 4g, 2g, 0g, 00g, 1/2', 9/16', 5/8'. Competitive prices and free shipping on orders over $20http://www.urbanbodyjewelry.com/spirals-talons-pinchers.html?flare=145&size_chart=178
sentinel HIV through blood transfusion
HIV THROUGH BLOOD TRANSFUSION. In the event that the insured contracted HIV as a result of blood transfusion, 10% on the Principal Sum Insured is payable. If you wish to apply for 'The Personal Sentinel' coverage, just instruct us by e-mail providing the following details and we will be sending you the appropriate Application Form:-. ...http://kooagency.com.my/sentinel_hivbloodtransfusion.htm
EARLY PHASE OF vCJD INFECTION IN BLOOD TRANSFUSION POSITION STATEMENT
Date: May 27, 2005 at 6:39 am PST. ##################### Bovine Spongiform Encephalopathy #####################. 1. POSITION STATEMENT. EARLY PHASE OF vCJD INFECTION IN BLOOD TRANSFUSION. RECIPIENTS. Issue. 1. The Committee on Microbiological Safety of Blood, Tissue and. Organs has requested advice from SEAC on whether a scientific. distinction can be drawn between historic and recent blood. transfusion recipients in terms of the relative load of the vCJD. agent that may be present in the bone, tissues or organs of the. blood transfusion recipient. In the context of this question, a recent. recipient is defined as having received a blood transfusion within. the week prior to bone, tissue or organ donation. A historic. recipient is defined as having received a blood transfusion in the. more distant past.. Background. 2. A pre-symptomatic diagnostic test for vCJD is currently not. available. Therefore, blood, bone, tissue or ...http://www.vegsource.com/talk/madcow/messages/94502.html
Overuse of blood transfusions increases infection risk | Veterinary Sciences Tomorrow
by Vetscite. Blood transfusions are one of the most common procedures patients receive in the hospital but the more red blood cells they receive, the greater their risk of infection, says a new study led by the University of Michigan Heath System and VA Ann Arbor Healthcare System. Researchers analyzed 21 randomized controlled trials for the study that appears in Journal of the American Medical Association (JAMA). Elderly patients undergoing hip or knee surgeries were most susceptible, with a 30 percent lower risk of infection when fewer transfusions were used. Overall, for every 38 hospitalized patients considered for a red blood cell transfusion (RBC), one patient would be spared a serious infection if fewer transfusions were used. Transfusions are often used for anemia or during surgery to make up for blood loss. The authors evaluated all health care-associated infections that were reported after receiving donor blood in ...http://vetscite.org/2014/04/overuse-of-blood-transfusions-increases-infection-risk/
Blood Transfusion in Resource-limited Settings | Anesthesiology | ASA Publications
As French physicians frequently and currently deployed in Theater of Operations in Africa, we read with interest the article by Ariyo et al.1 reviewing the anesthesia care provided at Médecins Sans Frontières facilities between 2008 and 2014. Spinal anesthesia was the most common type of anesthetic technique (34,413 [45.56%]), with cesarean section being the most common type of procedure performed (26,091 [34.54%]). Wound surgeries represented another common procedure type included in this retrospective study (18,547 [24.55%]). In this context, perioperative deaths occurred in 72 (0.21%) cases of obstetrics/gynecology and urology surgery and in only seven (0.06%) cases of wound surgeries. Nevertheless, the authors did not provide any details regarding the causes of death or any details about the incidence of perioperative bleeding and perioperative blood management. Perioperative blood management refers to perioperative blood transfusion and adjuvant therapies.2 Perioperative blood ...http://anesthesiology.pubs.asahq.org/article.aspx?articleid=2553806