Leukemic Infiltration Summary Report | CureHunter
The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest ... All types of leukemia show various degrees of infiltration, depending upon the type of leukemia. ... A pathologic change in leukemia in which leukemic cells permeate various organs at any stage of the disease. ... appearing in myelocytic leukemia, but infiltration is seen also in the granulocytic and lymphocytic types. The kidney is also a ...
Acute Myeloid Leukemia (AML) Clinical Presentation: History, Physical Examination
... disease manifestations may be the result of organ infiltration with leukemic cells. The most common sites of infiltration ... Occasionally, patients have skin rashes due to infiltration of the skin with leukemic cells (leukemia cutis). Chloromata are ... Signs relating to organ infiltration with leukemic cells include hepatosplenomegaly and, to a lesser degree, lymphadenopathy. ... Symptoms of organ infiltration with leukemic cells. Alternatively, ...
Category C - Diseases
CD44 engagement enhances acute myeloid leukemia cell adhesion to the bone marrow microenvironment by increasing VLA-4 avidity ...
CD44 reflects and mediates leukemic infiltration of bone marrow. We measured CD44 and CD49d surface expression of BM-derived ... targeting CD44 reduced leukemic repopulation in serial transplantations by eradication of leukemic stem cells.3 ... Requirement for CD44 in homing and engraftment of BCR-ABLexpressing leukemic stem cells. Nat Med. 2006; 12(10):1175-1180. https ... Selectins and their ligands are required for homing and engraftment of BCR-ABL1+ leukemic stem cells in the bone marrow niche. ...
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Astrovirus MLB2, a New Gastroenteric Virus Associated with Meningitis and Disseminated Infection - Volume 22, Number 5-May 2016...
Magnetic resonance imaging showed signs of meningeal leukemic infiltration without cerebral involvement. The patient ... Although meningeal infiltration had diminished, it was still detectable. Thus, the patient underwent cranial irradiation ... In March 2015, he experienced a headache and was ultimately given a diagnosis of a leukemic relapse, including meningeal ...
Frontiers | Anti-Leukemic Properties of Histamine in Monocytic Leukemia: The Role of NOX2
The clinical benefit of HDC/IL-2 is pronounced in monocytic forms of AML, where the leukemic cells express histamine type 2 ... The clinical benefit of HDC/IL-2 is pronounced in monocytic forms of AML where the leukemic cells express histamine type 2 ... These effects of HDC were absent in corresponding leukemic cells genetically depleted of NOX2 (NOX2−/−). We also observed that ... These effects of HDC were absent in corresponding leukemic cells genetically depleted of NOX2 (NOX2-/-). We also observed that ...
MLLT4 | Cancer Genetics Web
Histopathological results demonstrated severe leukemic infiltration in numerous organs in each group. Reverse transcription ... Times of leukemic onset in mice of S1, S2 and S3 groups were all earlier than that of the SHI-1 group, whereas the survival ... Moreover, the numbers of organs infiltrated by leukemic cells in S1, S2 and S3 groups were more than those in the SHI-1 group ( ... The presence of mature granulocytes/monocytes derived from leukemic cells in MLL-associated leukemia.. Int J Hematol. 2009; 90( ...
Zebrafish Model of Severe Combined Immunodeficiency (SCID) Due to JAK3 Mutation - PubMed
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Internal Medicine
Multiple cerebral hemorrhages under marked leukocyotosis was due to leukemic cell infiltration into the brain. Massive cerebral ... while leukemic cell infiltration occurred under a marked leukocyotosis (peripheral white blood cell count ,100, 000/μl). Four ... multiple hemorrhages due to leukemic cell infiltration (2 cases) and a single massive hemorrhage with petechial hemorrhages in ... Histologically, the biopsied pancreas was replaced by fibrous tissue with a small amount of mononuclear cell infiltration. She ...
IndexCat
Meningeal Infiltration of Chronic Myelomonocytic Leukemia
The diagnosis of central nervous system leukemic infiltration has to be confirmed by lumbar puncture and cytological ... Our patient had clinical presentation and laboratory findings which were suggestive for CNS leukemic infiltration. It is ... hyperviscosity and to prove leukemic infiltration of CNS. Only with this evidence it is possible to choose the right treatment ... less often skin infiltration or serous effusions. Meningeal leukemic involvement is rarely a presenting feature of CMML. We are ...
This Unusual Syndrome of the Face Could Be an Early Sign of AML | MedPage Today
Fast Five Quiz: Acute Leukemia
Frei, Emil 1997 - Office of NIH History and Stetten Museum
However, with combination, within three days, the bone pain would be gone, leukemic infiltration would start retreating, that ... But obviously that was not for export because the donor cells were in fact leukemic. But it did lead to efforts to get normal ... So what we set about to do was to systematically look at organ function, at leukemia infiltration, particularly leukemia ... infiltration of the marrow, to try to decide what is important, what correlates with survival and with complications, what can ...
Frontiers | Potential role of MAP2K1 mutation in the trans-differentiation of interdigitating dendritic cell sarcoma: Case...
Comprehensive genomic profiling of the formalin fixed the tumor tissue, and the cryopreserved leukemic cells revealed several ... Comprehensive genomic profiling of the formalin fixed tumor tissue and the cryopreserved leukemic cells revealed several common ... Four years later, systemic bone infiltration was discovered. Surgical resection of the IV rib and intensive chemotherapy led to ... Four years later, systemic bone infiltration was discovered. Surgical resection of the IV. rib and intensive chemotherapy led ...
Thieme E-Journals - Indian Journal of Medical and Paediatric Oncology / Full Text
Acute Myeloid Leukemia (AML) - Hematology and Oncology - MSD Manual Professional Edition
... symptoms of extramedullary leukemic infiltration are present in only about 5% of patients (often as skin manifestations). ... Patients may also have... read more ) caused by the rapid lysis of leukemic cells during initial therapy in AML. ... Meningeal infiltration can result in cranial nerve palsies, headache, visual or auditory symptoms, altered mental status, and ... Minimal residual disease is defined as having , 0.1 to 0.01% (based on the assay used) leukemic cells in bone marrow. In AML, ...
DeCS
Code System Concept
MeSH Browser
... "leukemic infiltration of the skin in lymphocytic leukemia" = LEUKEMIC INFILTRATION (IM) + SKIN /pathol (IM) (not SKIN ... Leukemic Infiltration Preferred Concept UI. M0026176. Scope Note. A pathologic change in leukemia in which leukemic cells ... Leukemic Infiltration Preferred Term Term UI T051433. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1993). ... The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest ...
MeSH Browser
... "leukemic infiltration of the skin in lymphocytic leukemia" = LEUKEMIC INFILTRATION (IM) + SKIN /pathol (IM) (not SKIN ... Leukemic Infiltration Preferred Concept UI. M0026176. Scope Note. A pathologic change in leukemia in which leukemic cells ... Leukemic Infiltration Preferred Term Term UI T051433. Date01/01/1999. LexicalTag NON. ThesaurusID NLM (1993). ... The degree of infiltration may vary from site to site. The liver and spleen are common sites of infiltration, the greatest ...
Different types of cancer, drugs can cause thrombotic microangiopathy, affect kidney health - news
... but certainly some of these patients can develop quite a lot of AKI as a result of TMA or leukemic and lymphoma infiltration. ... Of course, direct infiltration also occurs, but unlike leukemias, lymphomas can produce monoclonal proteins that can damage the ... Usually, in leukemias, the complication is through direct infiltration of the leukemia into the kidneys. In lymphoma, the ...