*  Radotinib in the treatment of chronic phase chronic myeloid leukemia patients | Haematologica
... in 77 patients with chronic phase-chronic myeloid leukemia (CP-CML) in a multinational phase II trial. After a median duration ... Radotinib in the treatment of chronic phase chronic myeloid leukemia patients Message Subject (Your Name) has forwarded a page ... Efficacy and safety of radotinib in chronic phase chronic myeloid leukemia patients with resistance or intolerance to BCR-ABL1 ... Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24- ...
  http://www.haematologica.org/content/100/1/e39
*  Monitoring CML patients responding to treatment with tyrosine kinase inhibitors: review and recommendations for harmonizing...
ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are ... in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell. 2002;2: 117-125. ... Although chronic myeloid leukemia (CML) was recognized as a distinct form of leukemia in the first half of the 19th century, it ... Detection of BCR-ABL transcripts in chronic myeloid leukemia (CML) using a "real time quantitative RT-PCR assay. Leukemia. 1999 ...
  http://www.bloodjournal.org/content/108/1/28?sso-checked=true
*  Dasatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia - AdisInsight
This study will investigate the efficacy and tolerability of dasatinib for the first-line treatment of patients with chronic ... Results assessing the efficacy and safety of dasatinib in patients with newly diagnosed chronic-phase chronic myeloid leukemia ... Dasatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia Completed Phase of Trial: Phase II ...
  http://adisinsight.springer.com/trials/700206540
*  Dasatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia in Japan - Full Text View - ClinicalTrials.gov
Leukemia. Leukemia, Myeloid. Leukemia, Myelogenous, Chronic, BCR-ABL Positive. Leukemia, Myeloid, Chronic-Phase. Neoplasms by ... Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Chronic Myeloid Leukemia Chronic Myeloproliferative ... Phase II Clinical Trial of Dasatinib First Line Therapy for Patients With Newly Diagnosed Chronic Myeloid Leukemia in Chronic ... Dasatinib in Newly Diagnosed Chronic-Phase Chronic Myeloid Leukemia in Japan (D-First). The recruitment status of this study is ...
  https://clinicaltrials.gov/show/NCT01464411
*  TYROSINE KINASE INHIBITOR (TKI) SWITCHING : EXPERIENCE FROM SIMPLICITY, A PROSPECTIVE OBSERVATIONAL STUDY OF CHRONIC-PHASE...
A PROSPECTIVE OBSERVATIONAL STUDY OF CHRONIC-PHASE CHRONIC MYELOID LEUKEMIA (CP-CML) PATIENTS IN CLINICAL PRACTICE. Hehlmann, R ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:766974
*  Medline ® Abstract for Reference 23 of 'Treatment of chronic myeloid leukemia in chronic phase after...
of 'Treatment of chronic myeloid leukemia in chronic phase after failure of initial therapy'. 23 ... Data demonstrating the superiority of nilotinib over imatinib in the frontline treatment of chronic myeloid leukemia (CML) and ... the role of BCR-ABL mutations in guiding tyrosine kinase inhibitor therapy in patients with chronic myeloid leukemia. ... Leukemia Department, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. ejabbour@mdanderson.org ...
  http://www.uptodate.com/contents/treatment-of-chronic-myeloid-leukemia-in-chronic-phase-after-failure-of-initial-therapy/abstract/23
*  A Study of Dasatinib vs. High-Dose Imatinib (600 mg) in Patients With Chronic Phase Chronic Myeloid Leukemia (CML) Who Failed...
Leukemia. Leukemia, Myeloid. Leukemia, Myelogenous, Chronic, BCR-ABL Positive. Leukemia, Myeloid, Chronic-Phase. Neoplasms by ... Genetic and Rare Diseases Information Center resources: Myeloid Leukemia Chronic Myeloid Leukemia Chronic Myeloproliferative ... High-Dose Imatinib (600 mg) in Patients With Chronic Phase Chronic Myeloid Leukemia (CML) Who Failed to Achieve Complete ... Imatinib Mesylate in the Treatment of Subjects With Chronic Phase Philadelphia Chromosome-Positive Chronic Myeloid Leukemia Who ...
  https://clinicaltrials.gov/ct2/show/study/NCT00362466?show_locs=Y
*  Bosutinib in Newly Diagnosed Chronic-Phase Philadelphia Chromosome-Positive Chronic Myeloid Leukemia - The ASCO Post
Bosutinib in Newly Diagnosed Chronic-Phase Philadelphia Chromosome-Positive Chronic Myeloid Leukemia. By Matthew Stenger. March ... approval for the treatment of newly diagnosed chronic-phase Philadelphia chromosome-positive chronic myeloid leukemia (CML).1,2 ... approval for the treatment of newly diagnosed chronic-phase Philadelphia chromosome-positive chronic myeloid leukemia (CML). ... Bosutinib versus imatinib for newly diagnosed chronic myeloid leukemia: Results from the randomized BFORE trial. J Clin Oncol ...
  http://ascopost.com/issues/march-10-2018/bosutinib-in-newly-diagnosed-chronic-phase-philadelphia-chromosome-positive-chronic-myeloid-leukemia/
*  Study of Dasatinib (BMS-354825) in Patients With Accelerated Phase Chronic Myeloid Leukemia
A Phase II Study of BMS-354825 in Subjects With Accelerated Phase Chronic Myeloid Leukemia Resistant to or Intolerant of ... A Phase II Study of BMS-354825 in Subjects With Accelerated Phase Chronic Myeloid Leukemia Resistant to or Intolerant of ... positive (BCR/ABL+) accelerated phase chronic myeloid leukemia (CML) whose disease. has primary or acquired hematologic ... Phase 2. Minimum Age:. 18 Years. Maximum Age:. N/A. Enrollment Status:. Not Enrolling. Gender:. Both. Conditions:. Chronic ...
  http://www.knowcancer.com/cancer-trials/NCT00101647/
*  6-Hydroxymethylacylfulvene in Treating Patients With Refractory Myelodysplastic Syndrome, Acute Myeloid Leukemia, Acute...
Acute Myeloid Leukemia, Acute Lymphocytic Leukemia, or Blastic Phase Chronic Myelogenous Leukemia. The safety and scientific ...
  https://clinicaltrials.gov/ct2/show/results/NCT00003997
*  Evaluation of the Safety of Imatinib Mesylate in 200 Iraqi Patients with Chronic Myeloid Leukemia in the Chronic Phase: Single...
Evaluation of the Safety of Imatinib Mesylate in 200 Iraqi Patients with Chronic Myeloid Leukemia in the Chronic Phase: Single- ... Evaluation of the Safety of Imatinib Mesylate in 200 Iraqi Patients with Chronic Myeloid Leukemia in the Chronic Phase: Single- ... Keywords: Safety, Imatinib, Chronic myeloid leukemia. matinib Mesilat n Kronik Faz Kronik Myeloid L semi Tan l 200 Irakl ... OBJECTIVE: Imatinib mesylate, a tyrosine kinase inhibitor, is presently the drug of choice for chronic myeloid leukemia (CML). ...
  http://www.tjh.com.tr/jvi.aspx?pdir=tjh&plng=eng&un=TJH-82346&look4=
*  Imatinib Combined with Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation versus Imatinib Alone for Chronic...
Allogeneic Hematopoietic Stem Cell Transplantation versus Imatinib Alone for Chronic Myeloid Leukemia in Chronic Phase Next ... Allogeneic Hematopoietic Stem Cell Transplantation versus Imatinib Alone for Chronic Myeloid Leukemia in Chronic Phase ...
  http://adisinsight.springer.com/trials/700227726?error=cookies_not_supported&code=9c896aca-58ba-4edb-813d-fb90b170dbd3
*  Imatinib Completed Phase 3 Trials for Chronic Myeloid Leukemia (CML) Treatment - DrugBank
Imatinib Completed Phase 3 Trials for Chronic Myeloid Leukemia (CML) Treatment. Back to Imatinib ... Compare Bosutinib To Imatinib In Subjects With Newly Diagnosed Chronic Phase Philadelphia Chromosome Positive CML. *DB06616 ( ...
  https://www.drugbank.ca/drugs/DB00619/clinical_trials?conditions=DBCOND0036419&phase=3&purpose=treatment&status=completed
*  Imatinib Completed Phase 1 Trials for Chronic Myeloid Leukemia (CML) Treatment - DrugBank
Previously Untreated Chronic Myeloid Leukemia in Chronic Phase (CML-CP). *DB00316 (Acetaminophen) ... Imatinib Completed Phase 1 Trials for Chronic Myeloid Leukemia (CML) Treatment. Back to Imatinib ... Bioequivalence Study of Mesylate Imatinib Capsule in Chronic Myeloid Leukemia Body. *DB00619 (Imatinib) ...
  https://www.drugbank.ca/drugs/DB00619/clinical_trials?conditions=DBCOND0036419&phase=1&purpose=treatment&status=completed
*  A Phase II, Single Arm, Open Label Study of Treatment-Free Remission in Chronic Myeloid Leukemia (CML) chronic phase (CP)...
A Phase II, Single Arm, Open Label Study of Treatment-Free Remission in Chronic Myeloid Leukemia (CML) chronic phase (CP) ... A Phase II, Single Arm, Open Label Study of Treatment-Free Remission in Chronic Myeloid Leukemia (CML) chronic phase (CP) ...
  http://adisinsight.springer.com/trials/700224140?error=cookies_not_supported&code=3436a4a7-0db3-4d48-80b9-ea5a475a4a72
*  Imatinib Completed Phase 3 Trials for Leukemia,Myeloid, Chronic Treatment - DrugBank
Imatinib Completed Phase 3 Trials for Leukemia,Myeloid, Chronic Treatment. Back to Imatinib ... High-Dose Gleevec Alone or in Combination With Peg-Intron and GM-CSF in Early Phase Chronic Myelogenous Leukemia (CML). * ...
  https://www.drugbank.ca/drugs/DB00619/clinical_trials?conditions=DBCOND0029677&phase=3&purpose=treatment&status=completed
*  Vaccine Therapy and Imatinib Mesylate in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia
Leukemia, Myeloid. *Leukemia, Myelogenous, Chronic, BCR-ABL Positive. *Leukemia, Myeloid, Chronic-Phase ... Diagnosis of chronic myelogenous leukemia. - Chronic phase disease. - Philadelphia chromosome positive disease. - Disease in ... imatinib mesylate in patients with persistent chronic phase chronic myelogenous. leukemia in first hematologic response.. - ... Trial Phase:. Phase 1. Minimum Age:. 18 Years. Maximum Age:. N/A ... chronic phase chronic myelogenous leukemia. *Philadelphia ...
  http://www.knowcancer.com/cancer-trials/NCT00301093/
*  Sargramostim in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Who Are Not in Complete Cytogenetic Remission...
Phase II Study of GM-CSF in Patients With Chronic Phase Chronic Myeloid Leukemia (CP-CML) Who Are Not in Complete Cytogenetic ... Phase II Study of GM-CSF in Patients With Chronic Phase Chronic Myeloid Leukemia (CP-CML) Who Are Not in Complete Cytogenetic ... Histologically confirmed chronic phase chronic myelogenous leukemia (CML). - Presence of t(9;22)(q34;q11) with at least 20 ... of the bone marrow in patients with chronic phase chronic myelogenous leukemia who are. not in complete cytogenetic remission ...
  http://www.knowcancer.com/cancer-trials/NCT00072579/
*  A Phase 1/2 Study of Ponatinib in Japanese Patients With Chronic Myeloid Leukemia (CML) and Ph+ Acute Lymphoblastic Leukemia ...
Leukemia. Leukemia, Myeloid. Precursor Cell Lymphoblastic Leukemia-Lymphoma. Leukemia, Lymphoid. Leukemia, Myelogenous, Chronic ... MedlinePlus related topics: Chronic Lymphocytic Leukemia Chronic Myeloid Leukemia Leukemia Drug Information available for: ... Genetic and Rare Diseases Information Center resources: Acute Lymphoblastic Leukemia Myeloid Leukemia Chronic Myeloid Leukemia ... Phase Chronic Myeloid Leukemia (CML) Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL) Drug: ponatinib - ...
  https://clinicaltrials.gov/ct2/show/NCT01667133
*  Comprehensive evaluation of time-to-response parameter as a predictor of treatment failure following imatinib therapy in...
Early recognition of high-risk patient is important to improve long-term outcomes following imatinib therapy for chronic ... myeloid leukemia (CML). Some controversy surrounds the question, which of short-term response parameters at which time-point, ... response parameter as a predictor of treatment failure following imatinib therapy in chronic phase chronic myeloid leukemia: ... Leukemia, Myeloid, Chronic-Phase / drug therapy*. Piperazines / therapeutic use*. Predictive Value of Tests*. Proportional ...
  http://www.biomedsearch.com/nih/Comprehensive-evaluation-time-to-response/20882527.html
*  Tacrolimus and Mycophenolate Mofetil in Preventing Graft-Versus-Host Disease in Patients Who Have Undergone Total-Body...
Phase Accelerated Phase Chronic Myelogenous Leukemia Adult Acute Lymphoblastic Leukemia in Remission Adult Acute Myeloid ... Chronic Lymphocytic Leukemia Leukemia, B-cell, Chronic Myeloid Leukemia Acute Myeloid Leukemia Acute Non Lymphoblastic Leukemia ... Blastic Phase Chronic Myelogenous Leukemia Childhood Acute Lymphoblastic Leukemia in Remission Childhood Acute Myeloid Leukemia ... Adult Acute Myeloid Leukemia With Del(5q) Adult Acute Myeloid Leukemia With Inv(16)(p13;q22) Adult Acute Myeloid Leukemia With ...
  https://clinicaltrials.gov/ct2/show/NCT00089011?recr=Open&cond=%22Mycoses%22&rank=3
*  Lyme Disease - Cancer Therapy Advisor
FDA Approves Bosutinib for Newly Diagnosed Chronic Myeloid Leukemia Featured. Chronic Myeloid Leukemia: Choosing A TKI ... A controversial phase of Lyme disease, called post-Lyme disease syndrome, posttreatment chronic Lyme disease, or chronic Lyme ... Chronic Lyme disease: chronic fatigue syndrome or fibromyalgia, which tend to produce more generalized and disabling symptoms, ... "Chronic Lyme Disease". Infect Dis Clin North Am. vol. 29. 2015. pp. 325-40. ...
  https://www.cancertherapyadvisor.com/hospital-medicine/lyme-disease/article/605117/
*  JCI - Volume 127, Issue 5
The mixed-lineage leukemia (. MLL. ) gene often fuses with ENL. and AF10. family genes in leukemia. However, the functional ... KDR expression increased in myeloid cells as myeloid-derived suppressor cells (MDSCs) accumulated, which was associated with ... Together, the results of these two studies lay the groundwork for future studies to determine how, in the face of chronic ... Clinical safety and therapeutic efficacy were evaluated in a phase II study. ...
  https://hzyouma.com.www.mobile.jci.org/127/5