alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 41-1023) protein (His tag)</span...
Recombinant alpha Ketoglutarate Dehydrogenase (alphaKGDHC) Protein (His tag). Species: Mouse (Murine). Source: Insect Cells. ... The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It ... alpha Ketoglutarate Dehydrogenase (alphaKGDHC) (AA 41-1023) protein (His tag) alpha Ketoglutarate Dehydrogenase (alphaKGDHC) ( ... More product categories related to alpha Ketoglutarate Dehydrogenase Protein * 54 anti-alpha Ketoglutarate Dehydrogenase ...http://www.antibodies-online.com/protein/3135266/alpha+Ketoglutarate+Dehydrogenase+alphaKGDHC+AA+41-1023+protein+His+tag/
OGDH Gene - GeneCards | ODO1 Protein | ODO1 Antibody
Oxoglutarate Dehydrogenase, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The ... Localization of the gene (OGDH) coding for the E1k component of the alpha-ketoglutarate dehydrogenase complex to chromosome ... Oxoglutarate (Alpha-ketoglutarate) dehydrogenase (A5XEI0_HUMAN). *Oxoglutarate (Alpha-ketoglutarate) dehydrogenase (A5XEI1_ ... This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2- ...http://www.genecards.org/cgi-bin/carddisp.pl?gene=OGDH
Alpha-Ketoglutarate Dehydrogenase Deficiency | Syndromes: Rapid Recognition and Perioperative Implications |...
... the others being pyruvate dehydrogenase and branched-chain ketoacid dehydrogenase. Each of these enzymes is a complex of ... are identical in all 3 alpha-ketoacid dehydrogenases. Alpha-ketoglutarate dehydrogenase, fumarase, and succinate dehydrogenase ... Alpha-ketoglutarate dehydrogenase is an enzyme of the Krebs cycle that catalyzes the oxidation of alpha-ketoglutarate to ... Alpha-KGD deficiency; 2-Alpha-ketoglutarate dehydrogenase deficiency; Oxoglutaric aciduria; Oxoglutarate dehydrogenase. ...http://accessanesthesiology.mhmedical.com/content.aspx?bookid=852§ionid=49517214
User:RostyslavZvanych/The a-ketoglutarate dehydrogenase complex in Alzheimer's disease - Wikipedia
a b c d e f g h i Mastrogiacoma, F., Bergeron, C. and Kish, S.J., (1993) Brain α-ketoglutarate dehydrogenase complex activity ... The α-ketoglutarate dehydrogenase complex. The α-KGDHC is found in the tricarboxylic acid cycle (TCA), which situated ... The α-ketoglutarate dehydrogenase complex (KGDHC) is an enzyme involved in the citric acid cycle that consists of three ... 1. "Brain α-ketoglutarate dehydrogenase complex activity in Alzheimer's disease" by Mastrogiacoma, F., Bergeron, C. and Kish, S ...https://en.wikipedia.org/wiki/User:RostyslavZvanych/The_a-ketoglutarate_dehydrogenase_complex_in_Alzheimer%E2%80%99s_disease
RCSB PDB - 1CW4: CRYSTAL STRUCTURE OF K230M ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ALPHA-KETOGLUTARATE Literature...
Active site water molecules revealed in the 2.1 A resolution structure of a site-directed mutant of isocitrate dehydrogenase. ... CRYSTAL STRUCTURE OF K230M ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ALPHA-KETOGLUTARATE. *DOI: 10.2210/pdb1cw4/pdb ... ISOCITRATE DEHYDROGENASE A 416 Escherichia coli EC#: 126.96.36.199 IUBMB Mutation: K230M Gene Name(s): icd icdA icdE b1136 JW1122 ... Protein-ligand complexes in two dimensions, ACS Med. Chem. Lett., DOI: 10.1021/ml100164p. Ions and some metal complexes are ...http://www.rcsb.org/pdb/explore/litView.do?structureId=1CW4
RCSB PDB - 3O9Z: Crystal structure of the WlbA (WbpB) dehydrogenase from Thermus thermophilus in complex with NAD and alpha...
... dehydrogenase from Thermus thermophilus in complex with NAD and alpha-ketoglutarate at 1.45 angstrom resolution ... Crystal structure of the WlbA (WbpB) dehydrogenase from Thermus thermophilus in complex with NAD and alpha-ketoglutarate at ... the enzyme in a complex with NAD(H) and alpha-ketoglutarate, and the enzyme in a complex with NAD(H) and its substrate (UDP-N- ... Both alpha-ketoglutarate and the UDP-linked sugar bind in the WlbA active site with their carbon atoms (C-2 and C-3', ...https://www.rcsb.org/structure/3O9Z
Structural Biochemistry/Krebs Cycle (Citric Acid cycle) - Wikibooks, open books for an open world
Alpha-ketoglutarate is converted to succinyl-CoA and CO2 by the action of the α-ketoglutarate dehydrogenase complex. NAD+ is ... α-ketoglutarate+ CoA + NAD+ -(α-ketoglutarate dehydrogenase complex)-, succinyl-CoA + CO2A +NADH 5. Conversion of Succinyl-CoA ... The pyruvate dehydrogenase complex is composed of three different enzymes. Its complex is composed of members of a family of ... homologous complexes which include citric acid cycle enzyme a-ketoglutarate dehydrogenase complex. These complexes are very ...https://en.wikibooks.org/wiki/Structural_Biochemistry/Krebs_Cycle_
Pyruvic acid - DrugBank
2-ketoglutarate dehydrogenase complex deficiency. Disease. Warburg Effect. Metabolic. Argininosuccinic Aciduria. Disease. ... Pyruvate dehydrogenase activity. Specific Function. The pyruvate dehydrogenase complex catalyzes the overall conversion of ... Another is activation of pyruvate dehydrogenase, promoting its own oxidation by inhibiting pyruvate dehydrogenase kinase. ... UPyruvate dehydrogenase E1 component subunit beta, mitochondrial. Not Available. Human. UPyruvate kinase PKM. Not Available. ...https://www.drugbank.ca/drugs/DB00119
PRODUCTION OF 1,4 BUTANEDIOL IN A MICROORGANISM - MICROBIA, INC.
b) CoA-independent succinic semialdehyde dehydrogenase;. (c) α-ketoglutarate dehydrogenase complex;. (d) 4-aminobutyrate ... hydroxybutyrate dehydrogenase, a 1 ,3 propanediol dehydrogenase, cinnamyl-alcohol dehydrogenase, or an alcohol dehydrogenase. ... 3 propanediol dehydrogenase, cinnamyl-alcohol dehydrogenase, or an alcohol dehydrogenase; the polypeptide that catalyzes the ... CoA-dependent succinic semialdehyde dehydrogenase; (7) 4- hydroxybutanoate dehydrogenase; (8) [alphaj-ketoglutarate ...http://www.sumobrain.com/patents/wipo/Production-14-butanediol-in-microorganism/WO2010085731.html
Excitatory Amino Acid Neurotoxicity | Springer for Research & Development
The alpha-ketoglutarate dehydrogenase complex. Ann NY Acad Sci 1999; 893 61-78.CrossRefGoogle Scholar ... The effects of calcium ions and adenine nucleotides on the activity of pig heart 2-oxoglutarate dehydrogenase complex. Biochem ... Herrero A, Barja G. ADP-regulation of mitochondria] free radical production is different with complex I- or complex II-linked ... A model of 02.-generation in the complex III of the electron transport chain. Mol Cell Biochem 1998; 184(1-2):21-33.PubMed ...https://rd.springer.com/chapter/10.1007/978-1-4615-0123-7_1
Difference between revisions of "Dahlquist:MAPP Archive" - OpenWetWare
2-ketoglutarate dehydrogenase complex. *Aromatic Compounds Degradation *Phenolic Compounds Degradation *Phenylacetate ...https://openwetware.org/wiki/?title=Dahlquist:MAPP_Archive&diff=prev&oldid=244851
KAKEN - Research Projects | Database of Supergene Family (KAKENHI-PROJECT-03558027)
Purification and molecular cloning of succinyltransferase of the rat a-ketoglutarate dehydrogenase complex.' J.Biol. Chem.266. ... Purification and molecular cloning of succinyltransferase of the rat α-ketoglutarate dehydrogenase complex.' J.Biol.Chem.266. ...https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-03558027/
Similar articles for PubMed (Select 22719765) - PubMed - NCBI
Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity. ... Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex.. Shi Q, Xu H, Yu H, Zhang N, Ye Y, ... Inhibition of alpha-ketoglutarate dehydrogenase complex promotes cytochrome c release from mitochondria, caspase-3 activation, ... Alpha-ketoglutarate dehydrogenase complex-dependent succinylation of proteins in neurons and neuronal cell lines. ...https://www.ncbi.nlm.nih.gov/pubmed?linkname=pubmed_pubmed&from_uid=22719765
Nontargeted Metabolite Profiling of Induced Pluripotent Stem Cells (iPSCs) Derived Neural Cells: Insights Into Mechanisms of...
Inactivation and reactivation of the mitochondrial α-ketoglutarate dehydrogenase complex. J Biol Chem. 2011;286(20):17640-8. ... pyruvate dehydrogenase, isocitrate dehydrogenase, and α-ketoglutarate dehydrogenase [81-83]. In addition, the levels of ATP and ... Inhibition of the alpha-ketoglutarate dehydrogenase complex alters mitochondrial function and cellular calcium regulation. ... An immunohistochemical study on alpha-ketoglutarate dehydrogenase complex in Parkinson's disease. Ann Neurol. 1994;35(2):204-10 ...https://www.intechopen.com/books/pluripotent-stem-cells-from-the-bench-to-the-clinic/nontargeted-metabolite-profiling-of-induced-pluripotent-stem-cells-ipscs-derived-neural-cells-insigh/
Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways...
... of the α-ketoglutarate dehydrogenase complex and malate dehydrogenase (MDH2)], the electron transport chain [ATP synthase ... 2005) The alpha-ketoglutarate-dehydrogenase complex: A mediator between mitochondria and oxidative stress in neurodegeneration ... Acetylation profiles of (B) succinate dehydrogenase subunit A (SDHA) from complex II in the ETC, (C) isocitrate dehydrogenase ( ... In the TCA cycle, both the α-ketoglutarate complex (KGDHC) and MDH2 had a ≥20-fold increase in acetylation levels at K153 and ...http://www.pnas.org/content/110/16/6601
Analysis of 13000 unique Citrus clusters associated with fruit quality, production and salinity tolerance | BMC Genomics | Full...
a-Ketoglutarate dehydrogenase complex. 188.8.131.52. No hits. No hits. Succinyl-CoA synthetase ... Sunkar R, Bartels D, Kirch HH: Overexpression of a stress-inducible aldehyde dehydrogenase gene from Arabidopsis thaliana in ... aldehyde dehydrogenases involved in detoxification [GenBank:DY301300 ] ; two genes of the inositol metabolism [GenBank: ...https://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2164-8-31
Pathogenesis of diencephalic lesions in an experimental model of Wernicke's encephalopathy | SpringerLink
Calingasan N.Y., Baker H., Sheu K.-F.R. and Gibson G.E. (1994). Distribution of the α-ketoglutarate dehydrogenase complex in ... 2. α-ketoglutarate dehydrogenase.Neurochem. Res. 11:567-577.CrossRefPubMedGoogle Scholar ...https://link.springer.com/article/10.1007%2FBF01991781
OGDH - Wikipedia
"Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity". The ... Alpha-ketoglutarate dehydrogenase also known as 2-oxoglutarate dehydrogenase E1 component, mitochondrial is an enzyme that in ... This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2- ... Evidence for direct association of the alpha-ketoglutarate dehydrogenase and dihydrolipoamide dehydrogenase components". The ...https://en.wikipedia.org/wiki/OGDH
KAKEN - Research Projects | Structure and expression of the human 2-oxoglutarate dehydrogenase gene (KAKENHI-PROJECT-05670149)
Publications] Kwan-Fu Rex Sheu: 'Abnormality of the alpha-ketoglutarate dehydrogenase complex in fibroblasts from familial ... Publications] Kwan-Fu Rex Sheu: 'Abnormality of the α-ketoglutarate dehydrogenase complex in fibroblasts from familial ... Publications] Kwan-Fu Rex Sheu: 'Abnormality of the alpha-ketoglutarate dehydrogenase complex in fibroblasts from familial ... The 2-oxoglutarate dehydrogenase (OGDH) complex that catalyzes oxidative decarboxylation of 2-oxoglutarate. It is apparent that ...https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-05670149/
DLST - Wikipedia
1998). "Subunit interactions in the mammalian alpha-ketoglutarate dehydrogenase complex. Evidence for direct association of the ... of human alpha-ketoglutarate dehydrogenase complex". Somat Cell Mol Genet. 20 (2): 99-105. doi:10.1007/BF02290679. PMID 8009371 ... 1990). "Inhibition of alpha-ketoglutarate dehydrogenase activity by a distinct population of autoantibodies recognizing ... Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial is an enzyme ...https://en.wikipedia.org/wiki/DLST
DLST Gene - GeneCards | ODO2 Protein | ODO2 Antibody
... of human alpha-ketoglutarate dehydrogenase complex. (PMID: 8009371) Ali G … Blass JP (Somatic cell and molecular genetics 1994) ... Dihydrolipoamide Succinyltransferase Component Of 2-Oxoglutarate Dehydrogenase Complex 4 * 2-Oxoglutarate Dehydrogenase Complex ... The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It ... The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It ...http://www.genecards.org/cgi-bin/carddisp.pl?id_type=entrezgene&id=1743
Lipoamide dehydrogenase | definition of lipoamide dehydrogenase by Medical dictionary
What is lipoamide dehydrogenase? Meaning of lipoamide dehydrogenase medical term. What does lipoamide dehydrogenase mean? ... Looking for online definition of lipoamide dehydrogenase in the Medical Dictionary? lipoamide dehydrogenase explanation free. ... a part of several enzyme complexes (for example, α-ketoglutarate dehydrogenase complex). Decreased activity leads to neuronal ... dihydrolipoamide dehydrogenase. (redirected from lipoamide dehydrogenase) di·hy·dro·lip·o·am·ide de·hy·dro·gen·ase. (dī-hī'drō- ...http://medical-dictionary.thefreedictionary.com/lipoamide+dehydrogenase
Protocols and Video Articles Authored by Kyle Denton (Translated to Spanish)
The activity of the mitochondrial Î±-ketoglutarate dehydrogenase complex (KGDHC) in homogenates from autopsy brain declines ... Deficits in the Mitochondrial Enzyme Î±-ketoglutarate Dehydrogenase Lead to Alzheimer's Disease-like Calcium Dysregulation ... The major problem in determining the role of Nef in HIV/AIDS has been the lack of tractable in vivo models where Nef's complex ... from complex environmental samples without the need for extensive growth of cultures. ...https://www.jove.com/author/Kyle_Denton?language=Spanish
Oxoglutarate dehydrogenase complex - Wikipedia
The oxoglutarate dehydrogenase complex (OGDC) or α-ketoglutarate dehydrogenase complex is an enzyme complex, most commonly ... Gibson, GE; Blass, J.P.; Beal, M.F.; Bunik, V. (2005). "The alpha-ketoglutarate-dehydrogenase complex: a mediator between ... Much like pyruvate dehydrogenase complex (PDC), this enzyme forms a complex composed of three components: Three classes of ... 2011). "Inactivation and Reactivation of the Mitochondrial α-Ketoglutarate Dehydrogenase Complex". The Journal of Biological ...https://en.wikipedia.org/wiki/Oxoglutarate_dehydrogenase_complex
Lipoyl synthase, chloroplastic (IPR027526) | InterPro | EMBL-EBI
... that is linked to a specific Lys as prosthetic group for the pyruvate and alpha-ketoglutarate dehydrogenase complexes and the ...https://www.ebi.ac.uk/interpro/entry/IPR027526