*  Anti-Isocitrate dehydrogenase antibody (ab116609)
Goat polyclonal Isocitrate dehydrogenase antibody validated for WB and tested in Sc. Immunogen corresponding to synthetic ... All lanes : Anti-Isocitrate dehydrogenase antibody (ab116609) at 0.5 µg/ml. Lane 1 : S. cerevisae isocitrate dehydrogenase ... Lane 2 : S. cerevisae isocitrate dehydrogenase wildtype lysate. Lysates/proteins at 35 µg per lane.. Developed using the ECL ... Mutations of Arg-132 to Cys, Gly or His abolish the conversion of isocitrate to alpha-ketoglutarate. Instead, alpha- ...
  http://www.abcam.com/isocitrate-dehydrogenase-antibody-ab116609.html
*  Species: Isocitrate lyase/phosphorylmutase, conserved site (IPR018523) | InterPro | EMBL-EBI
Species: Isocitrate lyase/phosphorylmutase, conserved site (IPR018523). Key Species. Key species. Number of proteins. FASTA. ...
  http://www.ebi.ac.uk/interpro/entry/IPR018523/taxonomy
*  Synpcc7942 1719 isocitrate dehydrogenase [Synechococcus elongatus PCC 7942] - Gene - NCBI
isocitrate dehydrogenase. Locus tag. Synpcc7942_1719. Gene type. protein coding. RefSeq status. VALIDATED. Organism. ... Synpcc7942_1719 isocitrate dehydrogenase [ Synechococcus elongatus PCC 7942 ] Gene ID: 3775419, discontinued on 5-Feb-2015 * ...
  https://www.ncbi.nlm.nih.gov/gene/3775419
*  Isocitrate Dehydrogenase Assay Kit (Colorimetric) (ab102528) Protocols
Abcam provides general protocols for Isocitrate Dehydrogenase Assay Kit (Colorimetric) (ab102528). Please download our pdf ...
  http://www.abcam.com/isocitrate-dehydrogenase-assay-kit-colorimetric-ab102528-protocols.html
*  IDH1 isocitrate dehydrogenase (NADP(+)) 1, cytosolic [Homo sapiens (human)] - Gene - NCBI
PTZ00435; isocitrate dehydrogenase; Provisional. * NM_001282387.1 → NP_001269316.1 isocitrate dehydrogenase [NADP] cytoplasmic ... isocitrate dehydrogenase [NADP] cytoplasmic. Names. NADP(+)-specific ICDH. NADP-dependent isocitrate dehydrogenase, cytosolic. ... Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two ... IDH1 isocitrate dehydrogenase (NADP(+)) 1, cytosolic [Homo sapiens] IDH1 isocitrate dehydrogenase (NADP(+)) 1, cytosolic [Homo ...
  https://www.ncbi.nlm.nih.gov/gene/3417
*  Apparent isocitrate lyase activity in Leishmania amazonensis : Acta Parasitologica
However, these results have been underestimated because genes for the two key enzymes of the cycle, isocitrate lyase (ICL) and ... Apparent isocitrate lyase activity in. *Anti-angiogenic and anti-lymphangiogenic role of praziquantel and artemether in ... Itaconate, an isocitrate lyase-directed inhibitor in Pseudomonas indigofera. Journal of Bacteriology, 131, 136-144PubMedGoogle ... Major roles of isocitrate lyase and malate synthase in bacterial and fungal pathogenesis. Microbiology, 155, 3166-3175. ...
  https://www.degruyter.com/view/j/ap.2017.62.issue-4/ap-2017-0084/ap-2017-0084.xml
*  aceA - Isocitrate lyase - Escherichia coli (strain K12) - aceA gene & protein
Catalyzes the reversible formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which ... Kcat is 28.5 sec(-1) for isocitrate lyase activity with threo-D-isocitrate as substrate (at pH 7.3).1 Publication. ,p>Manually ... IPR006254. Isocitrate_lyase. IPR018523. Isocitrate_lyase_ph_CS. IPR015813. Pyrv/PenolPyrv_Kinase-like_dom. ... IPR006254. Isocitrate_lyase. IPR018523. Isocitrate_lyase_ph_CS. IPR015813. Pyrv/PenolPyrv_Kinase-like_dom. ...
  http://www.uniprot.org/uniprot/P0A9G6
*  icd - Isocitrate dehydrogenase [NADP] - gamma proteobacterium HdN1 - icd gene & protein
Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation. ,p>Information which has been generated by the UniProtKB ... Isocitrate dehydrogenase [NADP]UniRule annotation. ,p>Information which has been generated by the UniProtKB automatic ... tr,E1VK08,E1VK08_9GAMM Isocitrate dehydrogenase [NADP] OS=gamma proteobacterium HdN1 OX=83406 GN=icd PE=4 SV=1 ...
  http://www.uniprot.org/uniprot/E1VK08
*  RCSB PDB - Protein Feature View - Isocitrate dehydrogenase [NADP] - P16100 (IDH AZOVI)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
  http://www.rcsb.org/pdb/protein/P16100
*  icd - Isocitrate dehydrogenase [NADP] - Blastococcus saxobsidens (strain DD2) - icd gene & protein
Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation. ,p>Information which has been generated by the UniProtKB ... Isocitrate dehydrogenase [NADP]UniRule annotation. ,p>Information which has been generated by the UniProtKB automatic ... Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation. ,p>Information which has been generated ... tr,H6RLV4,H6RLV4_BLASD Isocitrate dehydrogenase [NADP] OS=Blastococcus saxobsidens (strain DD2) OX=1146883 GN=icd PE=3 SV=1 ...
  http://www.uniprot.org/uniprot/H6RLV4
*  WikiGenes - IDH1 - isocitrate dehydrogenase 1 (NADP+), soluble
Somatic cell genetic assignment of the human gene for mitochondrial NADP-linked isocitrate dehydrogenase to the long arm of ... Bistability in the isocitrate dehydrogenase reaction: an experimentally based theoretical study. Guidi, G.M., Carlier, M.F., ... Crystallization and preliminary X-ray diffraction studies of monomeric isocitrate dehydrogenase by the MAD method using Mn ... The human PICD gene encodes a cytoplasmic and peroxisomal NADP(+)-dependent isocitrate dehydrogenase. Geisbrecht, B.V., Gould, ...
  http://www.wikigenes.org/e/gene/e/3417.html
*  icd - Isocitrate dehydrogenase - Francisella tularensis subsp. novicida (strain U112) - icd gene & protein
Isocitrate dehydrogenaseImported. ,p>Information which has been imported from another database using automatic procedures.,/p ... tr,A0Q7T7,A0Q7T7_FRATN Isocitrate dehydrogenase OS=Francisella tularensis subsp. novicida (strain U112) OX=401614 GN=icd PE=4 ...
  http://www.uniprot.org/uniprot/A0Q7T7
*  JCI - Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas
Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas. Gary Kohanbash,1 Diego A. Carrera,1 ... Mutations in the isocitrate dehydrogenase genes IDH1 and IDH2 are among the first genetic alterations observed during the ... mutations in the isocitrate dehydrogenase IDH1 and IDH2 genes are of particular interest. These mutations have been found to be ... All IDH1 and IDH2 mutations identified to date affect a single amino acid located within the isocitrate-binding site (IDH1 [ ...
  https://www.jci.org/articles/view/90644
*  JCI - Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas
Downloading a figure as powerpoint requires a browser with javascript support. Enable javascript and try again For help please contact sysadmin@the-jci.org ...
  https://www.jci.org/assets/326765/powerpoint
*  idhM - Isocitrate dehydrogenase [NADP], mitochondrial precursor - Dictyostelium discoideum (Slime mold) - idhM gene & protein
... isocitrate dehydrogenase (NADP+) activity, magnesium ion binding, 2-oxoglutarate metabolic process, isocitrate metabolic ... Isocitrate dehydrogenase [NADP], mitochondrialAdd BLAST. 401. Proteomic databases. PaxDb, a database of protein abundance ... Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.. ,p>This subsection of the 'Function' section provides information relevant ... Belongs to the isocitrate and isopropylmalate dehydrogenases family.Curated. ,p>UniProtKB Keywords constitute a ,a href="http ...
  http://www.uniprot.org/uniprot/Q75JR2
*  IDH3B - Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor - Homo sapiens (Human) - IDH3B gene & protein
... role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) ... Isocitrate dehydrogenase [NAD] subunit beta, mitochondrialAdd BLAST. 351. Amino acid modifications. Feature key. Position(s). ... isocitrate dehydrogenase (NAD+) activity Source: ProtInc ,p>Traceable Author Statement,/p> ,p>Used for information from review ... isocitrate metabolic process Source: ProtInc ,p>Traceable Author Statement,/p> ,p>Used for information from review articles ...
  http://www.uniprot.org/uniprot/O43837
*  Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. - PubMed - NCBI
Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome.. Reitman ZJ1, Jin G, Karoly ED ... E) TCA and shuttling of citrate, isocitrate, and α-ketoglutarate to the cytosol. Dashed lines indicate exchange of a metabolite ... Point mutations of the NADP(+)-dependent isocitrate dehydrogenases 1 and 2 (IDH1 and IDH2) occur early in the pathogenesis of ... Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome ...
  https://www.ncbi.nlm.nih.gov/pubmed/21289278
*  Isocitrate Dehydrogenase 3 (NAD ) alpha Isocitrate Dehydrogenase 3 (NAD+) alpha ELISA Kits | Biocompare.com
... alpha Isocitrate Dehydrogenase 3 (NAD+) alpha ELISA Kits from leading suppliers on Biocompare. View specifications, prices, ... Isocitrate Dehydrogenase 3 (NAD ) alpha Isocitrate Dehydrogenase 3 (NAD+) alpha ELISA Kits. Clear ... Human Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, IDH3A ELISA Kit *Detection Target: isocitrate dehydrogenase ... Mouse Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, IDH3A ELISA Kit *Detection Target: isocitrate dehydrogenase ...
  https://www.biocompare.com/pfu/110627/soids/2-39925/Assay_Kit/ELISA_Isocitrate_Dehydrogenase_3_NAD_alpha
*  RCSB PDB - 1ISO: ISOCITRATE DEHYDROGENASE: STRUCTURE OF AN ENGINEERED NADP+--> NAD+ SPECIFICITY-REVERSAL MUTANT...
Determinants of cofactor specificity in isocitrate dehydrogenase: structure of an engineered NADP+ --> NAD+ specificity- ... Isocitrate/Isopropylmalate dehydrogenase- like Isocitrate/Isopropylmalate dehydrogenase- like Dimeric isocitrate & ...
  http://www.rcsb.org/pdb/explore/derivedData.do?structureId=1ISO
*  Isocitrate lyase - Wikipedia
Isocitrate lyase (EC 4.1.3.1), or ICL, is an enzyme in the glyoxylate cycle that catalyzes the cleavage of isocitrate to ... ICL competes with isocitrate dehydrogenase, an enzyme found in the TCA cycle, for isocitrate processing. Flux through these ... Deactivation of isocitrate dehydrogenase by phosphorylation thus leads to increased isocitrate channeling through ICL, as seen ... threo-Ds-isocitrate glyoxylate-lyase, and isocitrate glyoxylate-lyase. This enzyme participates in glyoxylate and dicarboxylate ...
  https://en.wikipedia.org/wiki/Isocitrate_lyase
*  Isocitrate epimerase - Wikipedia
In enzymology, an isocitrate epimerase (EC 5.1.2.6) is an enzyme that catalyzes the chemical reaction (1R,2S)-1-hydroxypropane- ... Hoshiko S, Kunimoto Y, Arima K, Beppu T (1982). "Mechanism of L-alloisocitric acid fermentation: isocitrate epimerase activity ...
  https://en.wikipedia.org/wiki/Isocitrate_epimerase
*  Isocitrate dehydrogenase - Wikipedia
Using the enzyme isocitrate dehydrogenase (IDH), isocitrate is held within its active site by surrounding arginine, tyrosine, ... Isocitrate dehydrogenase catalysis,catalyze the chemical reactions Isocitrate + NAD+ ⇌ {\displaystyle \rightleftharpoons } 2- ... "The Crystal Structure of Porcine Mitochondrial NADP+-dependent Isocitrate Dehydrogenase Complexed with Mn2+ and Isocitrate". ... Eukaryotic isocitrate dehydrogenase enzymes on the other hand, have not been fully discovered yet. Each dimer of IDH has two ...
  https://en.wikipedia.org/wiki/Isocitrate_dehydrogenase
*  RCSB PDB - 1CW4: CRYSTAL STRUCTURE OF K230M ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ALPHA-KETOGLUTARATE Literature...
Active site water molecules revealed in the 2.1 A resolution structure of a site-directed mutant of isocitrate dehydrogenase. ... ISOCITRATE DEHYDROGENASE A 416 Escherichia coli EC#: 1.1.1.42 IUBMB Mutation: K230M Gene Name(s): icd icdA icdE b1136 JW1122 ... CRYSTAL STRUCTURE OF K230M ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ALPHA-KETOGLUTARATE. *DOI: 10.2210/pdb1cw4/pdb ...
  http://www.rcsb.org/pdb/explore/litView.do?structureId=1CW4
*  Isocitrate dehydrogenase 1-snail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell...
Background The isocitrate dehydrogenase (IDH) gene family expresses key functional metabolic enzymes in the Krebs cycle and ... Isocitrate dehydrogenase 1 (IDH1) expression was significantly lower in breast cancer a Protein levels of IDH1 and IDH2 in ... Abbreviations: IDH isocitrate dehydrogenase, IDC invasive ductal carcinoma, DSS disease-specific survival, DFS disease-free ... The isocitrate dehydrogenase (IDH) gene family expresses key functional metabolic enzymes in the Krebs cycle and mediates the ...
  https://link.springer.com/article/10.1186/s13058-018-0953-7
*  Isocitrate lyase family - Wikipedia
Isocitrate lyase (EC 4.1.3.1) is an enzyme that catalyzes the conversion of isocitrate to succinate and glyoxylate. This is the ... Tanaka A, Atomi H, Ueda M, Hikida M, Hishida T, Teranishi Y (1990). "Peroxisomal isocitrate lyase of the n-alkane-assimilating ... Isocitrate lyase family is a family of evolutionarily related proteins. ... Isocitrate lyase InterPro: IPR006254 Methylisocitrate lyase InterPro: IPR012695 Carboxyvinyl-carboxyphosphonate ...
  https://en.wikipedia.org/wiki/Isocitrate_lyase_family