Isocitrate lyase - Wikipedia
... threo-Ds-isocitrate glyoxylate-lyase, and isocitrate glyoxylate-lyase. This enzyme participates in glyoxylate and dicarboxylate ... Isocitrate lyase (EC 4.1.3.1), or ICL, is an enzyme in the glyoxylate cycle that catalyzes the cleavage of isocitrate to ... Glyoxylate cycle Isocitrate lyase family Britton KL, Abeysinghe IS, Baker PJ, Barynin V, Diehl P, Langridge SJ, et al. ( ... Gould TA, van de Langemheen H, Muñoz-Elías EJ, McKinney JD, Sacchettini JC (August 2006). "Dual role of isocitrate lyase 1 in ...
RCSB PDB - 1DQU: CRYSTAL STRUCTURE OF THE ISOCITRATE LYASE FROM ASPERGILLUS NIDULANS
CRYSTAL STRUCTURE OF THE ISOCITRATE LYASE FROM ASPERGILLUS NIDULANS ... Isocitrate Lyase from Aspergillus Nidulans: Crystallization and X-ray Analysis of a Glyoxylate Cycle Enzyme.. Langridge, S.J.,& ... Isocitrate lyase catalyses the first committed step of the carbon-conserving glyoxylate bypass, the Mg(2+)-dependent reversible ... Isocitrate lyase catalyses the first committed step of the carbon-conserving glyoxylate bypass, the Mg(2+)-dependent reversible ...
Acta Parasitologica Volume 62 Issue 4
PLAZA 3.0 Dicots : Binding Sites
Molecular and Functional Characterization of theRhodopseudomonas palustris No. 7 Phosphoenolpyruvate Carboxykinase Gene |...
7, and isocitrate lyase activity was found to be induced in ethanol- and acetate-grown cells (42). Further studies are ... Tahama H., Shinoyama H., and Fujii T. Reaction mechanisms of isocitrate lyase from Rhodopseudomonas sp. No. 7.Biosci. Biotech. ... PYK, pyruvate kinase; MDH, malate dehydrogenase; ICL, isocitrate lyase; Ac-CoA, acetyl-coenzyme A; ND, not detected. The open ... Possible candidates include pyruvate carboxylase (PC) and glyoxylate cycle enzymes, including isocitrate lyase and malate ...
Presence of Glyoxylate Cycle Enzymes in the Mitochondria of Euglena gracilis
Isocitrate lyase and malate synthase are specific enzymes of the glyoxylate cycle, used here as glyoxysomal markers. Both ...
Disinfection exhibits systematic impacts on the drinking water microbiome | Microbiome | Full Text
Specifically, isocitrate lyase (aceA: K01637) and malate synthase (aceB: K01638), two key genes involved in the glyoxylate ...
TCA cycle (aka Krebs or citric acid cycle) (WP78) - Homo sapiens | WikiPathways
Reversibility of isocitrate dehydrogenase and involvement of ATP-citrate lyase in gluconeogenesis. Des Rosiers C, Di Donato L, ... D-threo-Isocitrate. Metabolite. hmdb:HMDB0000193. The ChEBI ID with the correct charge is: 15562. ... The conversion of citrate into cis-aconitate and isocitrate in the presence of aconitase. KREBS HA, HOLZACH O. Biochem J. 1952 ... Reverse flux through cardiac NADP(+)-isocitrate dehydrogenase under normoxia and ischemia. Comte B, Vincent G, Bouchard B, ...
RCSB PDB - 3LYE: Crystal structure of oxaloacetate acetylhydrolase
Oxalacetate acetylhydrolase (OAH), a member of the phosphoenolpyruvate mutase/isocitrate lyase superfamily, catalyzes the ... Oxalacetate is the main OAH substrate, but the enzyme also acts as a lyase of (2R,3S)-dimethyl malate with approximately 1000- ... Comparison between the OAH structure and that of the closely related enzyme, 2,3-dimethylmalate lyase, suggests potential ...
The Differential Gene Expression Pattern of Mycobacterium tuberculosis in Response to Capreomycin and PA-824 versus First-Line...
However, a finding that the persistence of M. tuberculosis in mice requires the glyoxylate shunt enzyme isocitrate lyase (ICL ... In our prior study on capreomycin, the upregulation of isocitrate lyase (ICL) suggests that capreomycin can affect the ... "Persistence of Mycobacterium tuberculosis in macrophages and mice requires the glyoxylate shunt enzyme isocitrate lyase," ...
Challenge project: Designing Itaconate Based Covalent Inhibitors for Tuberculosis: An In-silico Study • BioSolveIT
In SeeSAR software, protein structure of isocitrate lyase was downloaded from Protein Data Bank. Then its binding site was ... Further, these molecules were covalently docked with isocitrate lyase using SeeSAR. The affinity of selected molecules towards ... Itaconate, a mammalian antimicrobial metabolite has shown excellent efficiency against isocitrate lyase that causes ...
Ross Ewen Beever
Volume 66, Issue 2 | Microbiology Society
Many experienced nurses and midwives identify the quality of their interpersonal relationships as the single most significant...
CoP: Co-expressed Biological Processes
New insights into Escherichia coli metabolism: carbon scavenging, acetate metabolism and carbon recycling responses during...
In agreement, the isocitrate lyase specific activity (Icl or AceA, one of the glyoxylate shunt enzyme) was detected in JM101 ... Isocitrate lyase (Icl): 50 mM morpholipepropanesulfonic acid (MOPS; pH, 7.3), 1 mM EDTA, 5 mM MgCl2, 4 mM phenylhydrazine HCl ( ... Isocitrate dehydrogenase (Icdh): 50 mM phosphate buffer (pH 7.5), 5 mM MgCl2, 2 mM NADP+, 2.5 mM D,L isocitrate [81]. ... Aoshima M, Ishii M, Yamagishi A, Oshima T, Igarashi Y: Metabolic characteristics of an isocitrate dehydrogenase defective ...
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- University of Strathclyde
A new path for killing pathogenic bacteria - EPFL
... the enzyme isocitrate dehydrogenase keeps it for the fat-metabolism and energy production cycle; the enzymes isocitrate lyase ... But if isocitrate goes the biosynthesis route, it must be replenished or else the energy-producing cycle will stop. Devastating ... The results showed that the mycobacterium decides where to direct isocitrate by using a mechanism that is not like a simple on- ... The molecule in question is called isocitrate, which, once produced, can go in two directions: continue the energy production ...
Comparative metabolomics of Phialemonium curvatum as an omnipotent fungus cultivated on crude palm oil versus glucose |...
... isocitrate lyase will need to provide malate synthase with glyoxylate. The detected increase in isocitrate lyase activity is ... Isocitrate lyase (ICL) and isocitrate dehydrogenase (IDH) involved in regulating TCA and glyoxylate cycle were shown ... Enzymatic assay of isocitrate lyase, isocitrate dehydrogenase, and succinate dehydrogenase assay. The enzymatic activity of ... Bowyer P, De Lucas JR, Turner G. Regulation of the expression of the isocitrate lyase gene (acuD) of Aspergillus nidulans. MGG ...
Related GMR Articles | Page 4 | GMR | Genetics and Molecular Research | The Original by FUNPEC-RP
Alcohol Dehydrogenase; Catalase; Esterases; Germination; Glutamate Dehydrogenase; Isocitrate lyase; Malate dehydrogenase; ...
SustainPineDB
AutoFact: Isocitrate lyase n=1 Tax=Pinus taeda RepID=Q41084_PINTA 9.0e-31 ... AutoFact: Isocitrate lyase n=1 Tax=Pinus taeda RepID=ACEA_PINTA 0.0 ... AutoFact: Isocitrate lyase n=1 Tax=Pinus taeda RepID=Q41084_PINTA 0.0 ... FL-Next: sp=Isocitrate lyase; Pinus taeda (Loblolly pine). 0.0 • Sma3: Isocitrate lyase 2.8026e-45 ...
Regulon of PsrA in Shewanella amazonensis SB2B
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The glyoxylate cycle is involved in pleotropic phenotypes, antagonism and induction of plant defence responses in the fungal...
Isocitrate lyase (ICL), a signature enzyme of the glyoxylate cycle, is required for metabolism of non-fermentable carbon ... Isocitrate lyase (ICL), a signature enzyme of the glyoxylate cycle, is required for metabolism of non-fermentable carbon ... Antagonism; Biocontrol; Glyoxylate cycle; Isocitrate lyase; Trichoderma atroviride Publicerad i. Fungal Genetics and Biology. ...
glycine biosynthesis in Pseudomonas stutzeri RCH2
EC 4.1.3 and EC 4.1.99
EC 4.1.3 Oxo-Acid-Lyases. EC 4.1.99 Other Carbon-Carbon Lyases. EC 4.1.3 Oxo-Acid-Lyases. Contents. EC 4.1.3.1 isocitrate lyase ... Ds-isocitrate glyoxylate-lyase; isocitrate glyoxylate-lyase. Systematic name: isocitrate glyoxylate-lyase (succinate-forming). ... EC 4.1.3.46 (R)-citramalyl-CoA lyase Entries. EC 4.1.3.1. Accepted name: isocitrate lyase. Reaction: isocitrate = succinate + ... NANA lyase; acetylneuraminate pyruvate-lyase; N-acetylneuraminate pyruvate-lyase; NanA; N-acetylneuraminate pyruvate-lyase (N- ...
CoP: Co-expressed Biological Processes
F:isocitrate lyase activity, catalytic activity;P:metabolic process;C:chloroplast, chloroplast stroma;OBFPAM. O.I.. C.G.. H.G. ... F:lyase activity, magnesium ion binding;P:metabolic process;C:unknown;PO. O.I.. C.G.. H.G.. Please select. TAIR (integral). ... F:lyase activity, magnesium ion binding;P:metabolic process;C:unknown;PO. O.I.. C.G.. H.G.. Please select. TAIR (integral). ...