*  Properties of halophil nicotinamide-adenine dinucleotide phosphate-specific isocitrate dehydrogenase. True Michaelis constants,...
True values of Michaelis constants of the NADP+-specific isocitrate dehydrogenase from Halobacterium salinarium were not very ... Properties of halophil nicotinamide-adenine dinucleotide phosphate-specific isocitrate dehydrogenase. True Michaelis constants ... Properties of halophil nicotinamide-adenine dinucleotide phosphate-specific isocitrate dehydrogenase. True Michaelis constants ... Properties of halophil nicotinamide-adenine dinucleotide phosphate-specific isocitrate dehydrogenase. True Michaelis constants ...
  http://www.biochemj.org/content/130/3/645
*  Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial
Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the ... Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two ... The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is ... NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid ...
  https://pharos.nih.gov/idg/targets/P51553
*  IDP2 (YLR174W) Result Summary | BioGRID
Catalyzes Oxidation Of Isocitrate To Alpha-ketoglutarate; Levels Are Elevated During Growth On Non-fermentable Carbon Sources ... isocitrate dehydrogenase (NADP(+)) IDP2, L000002737, YLR174W. Cytosolic NADP-specific isocitrate dehydrogenase; catalyzes ... oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced ...
  https://thebiogrid.org/31445/table/saccharomyces-cerevisiae/idp2.html
*  Isocitrate Dehydrogenase Assay Kit (Colorimetric) (ab102528) Protocols
Abcam provides general protocols for Isocitrate Dehydrogenase Assay Kit (Colorimetric) (ab102528). Please download our pdf ...
  http://www.abcam.com/isocitrate-dehydrogenase-assay-kit-colorimetric-ab102528-protocols.html
*  Metabolic alterations driven by IDH mutation in U251 ce | Open-i
... isocitrate dehydrogenase; LDH, lactate dehydrogenase; MAS, malate-aspartate shuttle; Pyr, pyruvate; TCA, tricarboxylic acid ... isocitrate dehydrogenase; LDH, lactate dehydrogenase; MAS, malate-aspartate shuttle; Pyr, pyruvate; TCA, tricarboxylic acid ... Somatic mutations in isocitrate dehydrogenase (IDH)-1 and -2 have recently been described in glioma. This mutation leads to a ... Somatic mutations in isocitrate dehydrogenase (IDH)-1 and -2 have recently been described in glioma. This mutation leads to a ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4385911_cddis201513f7&req=4
*  Evidence for an arginine residue at the coenzyme-binding site of Escherichia coli isocitrate dehydrogenase | Biochemical Journal
Evidence for an arginine residue at the coenzyme-binding site of Escherichia coli isocitrate dehydrogenase. J S McKee, H G ... The data indicate that the coenzyme-binding site of isocitrate dehydrogenase contains a reactive arginine residue that is ... Evidence for an arginine residue at the coenzyme-binding site of Escherichia coli isocitrate dehydrogenase ... Evidence for an arginine residue at the coenzyme-binding site of Escherichia coli isocitrate dehydrogenase ...
  http://www.biochemj.org/content/261/1/301
*  Isocitrate Dehydrogenase 1 Is a Novel Plasma Biomarker for the Diagnosis of Non-Small Cell Lung Cancer | Clinical Cancer...
Isocitrate Dehydrogenase 1 Is a Novel Plasma Biomarker for the Diagnosis of Non-Small Cell Lung Cancer. Nan Sun, Zhaoli Chen, ... Identification of isocitrate dehydrogenase 1 as a potential diagnostic and prognostic biomarker for non-small cell lung cancer ... Isocitrate Dehydrogenase 1 Is a Novel Plasma Biomarker for the Diagnosis of Non-Small Cell Lung Cancer ... Isocitrate Dehydrogenase 1 Is a Novel Plasma Biomarker for the Diagnosis of Non-Small Cell Lung Cancer ...
  http://clincancerres.aacrjournals.org/content/19/18/5136.full
*  Comparison of the effects of Ca2+, adenine nucleotides and pH on the kinetic properties of mitochondrial NAD+-isocitrate...
Yeast NAD(+)-isocitrate dehydrogenase exhibits a low K0.5 for isocitrate and is activated by AMP and ADP, but is insensitive to ... The regulatory properties of NAD(+)-isocitrate dehydrogenase and oxoglutarate dehydrogenase in extracts of yeast and rat heart ... In contrast, the rat heart NAD(+)-isocitrate dehydrogenase was insensitive to AMP, but was activated by ADP and by Ca2+ in the ... nucleotides and pH on the kinetic properties of mitochondrial NAD+-isocitrate dehydrogenase and oxoglutarate dehydrogenase from ...
  http://www.biochemj.org/content/303/2/461
*  Anti-Isocitrate dehydrogenase antibody (ab116609)
Goat polyclonal Isocitrate dehydrogenase antibody validated for WB and tested in Sc. Immunogen corresponding to synthetic ... All lanes : Anti-Isocitrate dehydrogenase antibody (ab116609) at 0.5 µg/ml. Lane 1 : S. cerevisae isocitrate dehydrogenase ... Lane 2 : S. cerevisae isocitrate dehydrogenase wildtype lysate. Lysates/proteins at 35 µg per lane.. Developed using the ECL ... corresponding to internal sequence amino acids 281-295 of Saccharomyces cerevisiae Isocitrate dehydrogenase (NP_014361). ...
  http://www.abcam.com/isocitrate-dehydrogenase-antibody-ab116609.html
*  IDH1 isocitrate dehydrogenase (NADP(+)) 1, cytosolic [Homo sapiens (human)] - Gene - NCBI
PTZ00435; isocitrate dehydrogenase; Provisional. * NM_001282387.1 → NP_001269316.1 isocitrate dehydrogenase [NADP] cytoplasmic ... isocitrate dehydrogenase [NADP] cytoplasmic. Names. NADP(+)-specific ICDH. NADP-dependent isocitrate dehydrogenase, cytosolic. ... IDH1 isocitrate dehydrogenase (NADP(+)) 1, cytosolic [Homo sapiens] IDH1 isocitrate dehydrogenase (NADP(+)) 1, cytosolic [Homo ... Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the ...
  https://www.ncbi.nlm.nih.gov/gene/3417
*  RCSB PDB - Protein Feature View - Isocitrate dehydrogenase [NADP] - P16100 (IDH AZOVI)
The PDB archive contains information about experimentally-determined structures of proteins, nucleic acids, and complex assemblies. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.
  http://www.rcsb.org/pdb/protein/P16100
*  icd - Isocitrate dehydrogenase [NADP] - gamma proteobacterium HdN1 - icd gene & protein
Isocitrate dehydrogenase [NADP]UniRule annotation. ,p>Information which has been generated by the UniProtKB automatic ... tr,E1VK08,E1VK08_9GAMM Isocitrate dehydrogenase [NADP] OS=gamma proteobacterium HdN1 OX=83406 GN=icd PE=4 SV=1 ... Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation. ,p>Information which has been generated by the UniProtKB ...
  http://www.uniprot.org/uniprot/E1VK08
*  WikiGenes - IDH1 - isocitrate dehydrogenase 1 (NADP+), soluble
Somatic cell genetic assignment of the human gene for mitochondrial NADP-linked isocitrate dehydrogenase to the long arm of ... Bistability in the isocitrate dehydrogenase reaction: an experimentally based theoretical study. Guidi, G.M., Carlier, M.F., ... Crystallization and preliminary X-ray diffraction studies of monomeric isocitrate dehydrogenase by the MAD method using Mn ... The human PICD gene encodes a cytoplasmic and peroxisomal NADP(+)-dependent isocitrate dehydrogenase. Geisbrecht, B.V., Gould, ...
  http://www.wikigenes.org/e/gene/e/3417.html
*  icd - Isocitrate dehydrogenase [NADP] - Blastococcus saxobsidens (strain DD2) - icd gene & protein
Isocitrate dehydrogenase [NADP]UniRule annotation. ,p>Information which has been generated by the UniProtKB automatic ... Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation. ,p>Information which has been generated ... tr,H6RLV4,H6RLV4_BLASD Isocitrate dehydrogenase [NADP] OS=Blastococcus saxobsidens (strain DD2) OX=1146883 GN=icd PE=3 SV=1 ... Isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH.UniRule annotation. ,p>Information which has been generated by the UniProtKB ...
  http://www.uniprot.org/uniprot/H6RLV4
*  icd - Isocitrate dehydrogenase - Francisella tularensis subsp. novicida (strain U112) - icd gene & protein
Isocitrate dehydrogenaseImported. ,p>Information which has been imported from another database using automatic procedures.,/p ... tr,A0Q7T7,A0Q7T7_FRATN Isocitrate dehydrogenase OS=Francisella tularensis subsp. novicida (strain U112) OX=401614 GN=icd PE=4 ...
  http://www.uniprot.org/uniprot/A0Q7T7
*  JCI - Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas
Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas. Gary Kohanbash,1 Diego A. Carrera,1 ... Mutations in the isocitrate dehydrogenase genes IDH1 and IDH2 are among the first genetic alterations observed during the ... mutations in the isocitrate dehydrogenase IDH1 and IDH2 genes are of particular interest. These mutations have been found to be ... All IDH1 and IDH2 mutations identified to date affect a single amino acid located within the isocitrate-binding site (IDH1 [ ...
  https://www.jci.org/articles/view/90644
*  JCI - Isocitrate dehydrogenase mutations suppress STAT1 and CD8+ T cell accumulation in gliomas
Downloading a figure as powerpoint requires a browser with javascript support. Enable javascript and try again For help please contact sysadmin@the-jci.org ...
  https://www.jci.org/assets/326765/powerpoint
*  idhM - Isocitrate dehydrogenase [NADP], mitochondrial precursor - Dictyostelium discoideum (Slime mold) - idhM gene & protein
... isocitrate dehydrogenase (NADP+) activity, magnesium ion binding, 2-oxoglutarate metabolic process, isocitrate metabolic ... Isocitrate dehydrogenase [NADP], mitochondrialAdd BLAST. 401. Proteomic databases. PaxDb, a database of protein abundance ... Belongs to the isocitrate and isopropylmalate dehydrogenases family.Curated. ,p>UniProtKB Keywords constitute a ,a href="http ... sp,Q75JR2,IDHP_DICDI Isocitrate dehydrogenase [NADP], mitochondrial OS=Dictyostelium discoideum GN=idhM PE=3 SV=1 ...
  http://www.uniprot.org/uniprot/Q75JR2
*  IDH3B - Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor - Homo sapiens (Human) - IDH3B gene & protein
... role to facilitate the assembly and ensure the full activity of the enzyme catalyzing the decarboxylation of isocitrate (ICT) ... Isocitrate dehydrogenase [NAD] subunit beta, mitochondrialAdd BLAST. 351. Amino acid modifications. Feature key. Position(s). ... isocitrate dehydrogenase (NAD+) activity Source: ProtInc ,p>Traceable Author Statement,/p> ,p>Used for information from review ... Cluster: Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial. 64. O43837-2. UPI000BB51C8E. UPI0008135940. UPI000BB4D11A ...
  http://www.uniprot.org/uniprot/O43837
*  Isocitrate Dehydrogenase 3 (NAD ) alpha Isocitrate Dehydrogenase 3 (NAD+) alpha ELISA Kits | Biocompare.com
... alpha Isocitrate Dehydrogenase 3 (NAD+) alpha ELISA Kits from leading suppliers on Biocompare. View specifications, prices, ... Isocitrate Dehydrogenase 3 (NAD ) alpha Isocitrate Dehydrogenase 3 (NAD+) alpha ELISA Kits. Clear ... Human Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, IDH3A ELISA Kit *Detection Target: isocitrate dehydrogenase ... Mouse Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial, IDH3A ELISA Kit *Detection Target: isocitrate dehydrogenase ...
  https://www.biocompare.com/pfu/110627/soids/2-39925/Assay_Kit/ELISA_Isocitrate_Dehydrogenase_3_NAD_alpha
*  RCSB PDB - 1ISO: ISOCITRATE DEHYDROGENASE: STRUCTURE OF AN ENGINEERED NADP+--> NAD+ SPECIFICITY-REVERSAL MUTANT...
Determinants of cofactor specificity in isocitrate dehydrogenase: structure of an engineered NADP+ --> NAD+ specificity- ... Isocitrate/Isopropylmalate dehydrogenase- like Dimeric isocitrate & isopropylmalate dehydrogenases Isocitrate dehydrogenase, ...
  http://www.rcsb.org/pdb/explore/derivedData.do?structureId=1ISO
*  RCSB PDB - 1CW4: CRYSTAL STRUCTURE OF K230M ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ALPHA-KETOGLUTARATE Literature...
Active site water molecules revealed in the 2.1 A resolution structure of a site-directed mutant of isocitrate dehydrogenase. ... ISOCITRATE DEHYDROGENASE A 416 Escherichia coli EC#: 1.1.1.42 IUBMB Mutation: K230M Gene Name(s): icd icdA icdE b1136 JW1122 ... CRYSTAL STRUCTURE OF K230M ISOCITRATE DEHYDROGENASE IN COMPLEX WITH ALPHA-KETOGLUTARATE. *DOI: 10.2210/pdb1cw4/pdb ...
  http://www.rcsb.org/pdb/explore/litView.do?structureId=1CW4
*  Isocitrate dehydrogenase 1-snail axis dysfunction significantly correlates with breast cancer prognosis and regulates cell...
Background The isocitrate dehydrogenase (IDH) gene family expresses key functional metabolic enzymes in the Krebs cycle and ... Isocitrate dehydrogenase 1 (IDH1) expression was significantly lower in breast cancer a Protein levels of IDH1 and IDH2 in ... Abbreviations: IDH isocitrate dehydrogenase, IDC invasive ductal carcinoma, DSS disease-specific survival, DFS disease-free ... The isocitrate dehydrogenase (IDH) gene family expresses key functional metabolic enzymes in the Krebs cycle and mediates the ...
  https://link.springer.com/article/10.1186/s13058-018-0953-7
*  Isocitrate dehydrogenase - Wikipedia
Using the enzyme isocitrate dehydrogenase (IDH), isocitrate is held within its active site by surrounding arginine, tyrosine, ... Isocitrate dehydrogenase catalysis,catalyze the chemical reactions Isocitrate + NAD+ ⇌ {\displaystyle \rightleftharpoons } 2- ... "The Crystal Structure of Porcine Mitochondrial NADP+-dependent Isocitrate Dehydrogenase Complexed with Mn2+ and Isocitrate". ... "Nondecarboxylating and decarboxylating isocitrate dehydrogenases: oxalosuccinate reductase as an ancestral form of isocitrate ...
  https://en.wikipedia.org/wiki/Isocitrate_dehydrogenase
*  Items where Author is "Tordai, Attila" - Repository of the Academy's Library
Location and type of isocitrate dehydrogenase mutations influence clinical characteristics and disease outcome of acute myeloid ...
  http://real.mtak.hu/view/creators/Tordai=3AAttila=3A=3A.default.html