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*  Iodocyanopindolol - Wikipedia
Iodocyanopindolol (INN) is a drug related to pindolol which acts as both a β1 adrenoreceptor antagonist and a 5-HT1A receptor ... Direct identification by (+/-)-[125I]iodocyanopindolol binding". Circulation Research. 53 (6): 752-758. doi:10.1161/01.res.53.6 ...
  https://en.wikipedia.org/wiki/Iodocyanopindolol
*  iodo-(±)-Cyanopindolol, [125I], 500µCi | PerkinElmer
iodo-(±)-Cyanopindolol, [125I], 500µCi Part Number : NEX174500UC *Overview. *Related Products & Services. *Tools ...
  https://www-punchout.perkinelmer.com/product/-cyanopindolol-125i-iodo-nex174500uc
*  ChemIDplus - 83498-72-0 - WGSPBWSPJOBKNT-UHFFFAOYSA-N - Iodocyanopindolol - Similar structures search, synonyms, formulas,...
Iodocyanopindolol - Similar structures search, synonyms, formulas, resource links, and other chemical information. ... Substance Name: Iodocyanopindolol. RN: 83498-72-0. InChIKey: WGSPBWSPJOBKNT-UHFFFAOYSA-N. Note. *. A highly selective and ...
  https://chem.nlm.nih.gov/chemidplus/rn/83498-72-0
*  Decrease in beta-adrenergic receptors of lymphocytes in spontaneously occurring acute asthma.
Iodocyanopindolol. Lymphocytes / metabolism*. Male. Middle Aged. Pindolol / analogs & derivatives, metabolism. Receptors, ...
  http://www.biomedsearch.com/nih/Decrease-in-beta-adrenergic-receptors/8393400.html
*  Atomoxetine - The Full Wiki
Iodocyanopindolol • Iprocrolol • Isoxaprolol • Isamoltane • Labetalol • Landiolol • Levobetaxolol • Levobunolol • ...
  http://www.thefullwiki.org/Atomoxetine
*  Plus it
Iodocyanopindolol ([125I]CYP) was prepared using cyanopindolol acquired from Sandoz (East Hanover, NJ) and 125I from New ...
  http://molpharm.aspetjournals.org/content/58/2/421
*  Effects of Angiotensin II Type 1 Receptor Blockade and Angiotensin-Converting Enzyme Inhibition on Cardiac β-Adrenergic Signal...
The antagonist affinity of [125I]iodocyanopindolol, as judged on the basis of the KD values, did not differ between the studied ... The ligand [125I]iodocyanopindolol was from Amersham. Dithiothreitol was from Serva. Pertussis toxin was from List Biological ... iodocyanopindolol bound/mg of protein) (n=7 to 10) (B). ...
  http://hyper.ahajournals.org/content/31/3/747
*  Membrane Target Systems: Adrenergic beta 3 (human) membrane preparation, in CHO-K1 cells. 400 Units. | PerkinElmer
We submit every batch of receptor to stringent quality control testing that includes saturation radioligand binding assay to determine receptor concentration (Bmax) and affinity (Kd). Competition binding assays are performed determine affinity (Ki) against known reference agonists and antagonists. GTPgS data is also provided for some of our Gi coupled receptors ...
  http://www.perkinelmer.com/product/adrenergic-beta-3-human-membrane-es-035-m400ua
*  Pathway and mechanism of drug binding to G-protein-coupled receptors | PNAS
Involvement of Tyr356(7.43) in (+/−)cyanopindolol but not (+/−)[125Iodo]cyanopindolol binding. Eur J Med Chem 39:625-631. ...
  https://www.pnas.org/content/108/32/13118
*  Characterization of a potentially reversible increase in beta-adrenergic receptors in isolated, neonatal rat cardiac myocytes...
Binding parameters were measured using [125I]iodocyanopindolol. After 4 hours incubation in potassium cyanide and 2- ... iodocyanopindolol.. *S. L. Petrović, John K. McDonald, Gary D. Snyder, S M Mccann ...
  https://www.semanticscholar.org/paper/Characterization-of-a-potentially-reversible-in-in-Buja-Muntz/30ad456422a57e9acecc669ab325b830fa694ae9
*  Uncoupling between beta-adrenoceptors and adenylate cyclase in dog ischemic myocardium | SpringerLink
... iodocyanopindolol binding, in the absence and presence of ±-isoprenaline and GTP, and 2. adenylate cyclase activity. The ...
  https://link.springer.com/article/10.1007%2FBF00498853
*  Vasopressin/Serotonin Interactions in the Anterior Hypothalamus Control Aggressive Behavior in Golden Hamsters | Journal of...
5-HT binding sites in the AH were labeled with a selective 5-HT1B ligand, [125I]-iodocyanopindolol ([125I]CYP) (Hoyer et al., ... 1985) Characterization of 5-HT1B recognition sites in rat brain: binding studies with (−)[125I]iodocyanopindolol. Eur J ... iodocyanopindolol (B), a selective 5-HT1B receptor ligand. The binding shown was performed on contiguous 20 μm coronal sections ...
  http://www.jneurosci.org/content/17/11/4331.long
*  The neurobiology of stress and gastrointestinal disease | Gut
Time-dependent effects of chronic psychosocial stress on [125I] iodocyanopindolol binding sites. Cell Mol Neurobiol 17:417-432. ...
  http://gut.bmj.com/content/47/6/861.full
*  Nebivolol - Wikipedia
A comparison of [3H]CGP 12.177 and [125I]iodocyanopindolol binding studies". Eur. J. Pharmacol. 460 (1): 19-26. doi:10.1016/ ...
  https://en.wikipedia.org/wiki/Nebivolol
*  Erythema nodosum - Renal and Urology News
Morin, D, Zini, R, Urien, S. "Labelling of rat brain beta-adrenoceptors: (3H)CGP-12177 or (125I) iodocyanopindolol?". J Recept ...
  http://www.renalandurologynews.com/pediatrics/erythema-nodosum/article/622872/
*  ValiScreen Adrenergic beta 3 (human) cell line | PerkinElmer
Stable recombinant cell line expressing the Adrenergic, B3 receptor. Human recombinant, in CHO-K1 host cell. We provide: Two vials of the recombinant cell line as frozen cells; Detailed product information including sequence, cell line properties, culture conditions, pharmacological properties of the recombinant receptor in binding and functional assays (cAMP). In addition, for total reassurance, we will provide up to two free replacements within in a 2 year period should you accidently lose your cell line ...
  http://www.perkinelmer.de/product/adrenergic-beta3-camp-frozen-cells-es-035-cf
*  Cyanopindolol - Wikipedia
Its radiolabelled derivative iodocyanopindolol has been widely used in mapping the distribution of beta adrenoreceptors in the ...
  https://en.wikipedia.org/wiki/Cyanopindolol
*  Methysergide - DrugBank
... iodocyanopindolol binding and inhibition of [3H]-5-hydroxytryptamine release. J Pharmacol Exp Ther. 1992 Feb;260(2):614-26. [ ...
  https://www.drugbank.ca/drugs/DB00247
*  Direct analysis of beta-adrenergic receptor subtypes on intact adult ventricular myocytes of the rat. | Circulation Research
125I]iodocyanopindolol binding to membranes prepared from nonmyocyte elements of rat ventricle occurs with a dissociation ... The beta-adrenergic antagonist ligand (+/-)-[125I] iodocyanopindolol binds to 2 X 10(5) receptors per purified adult rat ... Computer analysis of competition of [125I]iodocyanopindolol binding by betaxolol, practolol, and zinterol in nonmyocyte ... iodocyanopindolol-binding sites on intact myocytes in monophasic manners with dissociation constants of 46, 845, and 923 nM, ...
  http://circres.ahajournals.org/content/56/1/126
*  Plus it
... iodocyanopindolol binding to washed particles. For both ligands the number of binding sites was about 4-fold higher in ...
  http://cancerres.aacrjournals.org/content/46/5/2285
*  Localization of beta 1- and beta 2-adrenergic receptors in rat kidney by autoradiography. | Circulation Research
... iodocyanopindolol in the presence of the selective agents betaxolol (beta 1) and zinterol (beta 2). [125I]Iodocyanopindolol ... iodocyanopindolol labeling of the juxtaglomeruluar granule cells was abolished at lower concentrations (10(-8) M) of betaxolol ...
  http://circres.ahajournals.org/content/57/2/278
*  Age-Related ENOX Proteins (arNOX) | Springer for Research & Development
The iodocyanopindolol and SM-11044 binding protein belongs to the TM9SF multispanning membrane protein superfamily. Gene 273: ...
  https://rd.springer.com/chapter/10.1007/978-1-4614-3958-5_9
*  Ventricular Hypertrophy Plus Neurohumoral Activation Is Necessary to Alter the Cardiac β-Adrenoceptor System in Experimental...
The density of β-adrenoceptors in right and left ventricular crude membranes was determined by (−)-[125I]-iodocyanopindolol ( ... iodocyanopindolol (ICYP, specific activity 2200 Ci/mmol), and γ-[32P]-ATP were purchased from Perkin-Elmer Life Sciences (Köln ...
  http://circres.ahajournals.org/content/91/11/1056