Intracellular calcium-sensing proteins - Wikipedia
Intracellular calcium-sensing proteins are proteins that act in the second messenger system. Examples include: calmodulin ... Intracellular+Calcium-Sensing+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH) v t e (Human ... "The expanding superfamily of gelsolin homology domain proteins". Cytoskeleton. 70 (11): 775-95. doi:10.1002/cm.21149. PMID ...
Calreticulin | Harvard Catalyst Profiles | Harvard Catalyst
Carrier Proteins [D12.776.157]. *Calcium-Binding Proteins [D12.776.157.125]. *Intracellular Calcium-Sensing Proteins [D12.776. ... is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium ... A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to ... functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. ...
MeSH Browser
Carrier Proteins [D12.776.157] * Calcium-Binding Proteins [D12.776.157.125] * Intracellular Calcium-Sensing Proteins [D12.776. ... Proteins [D12.776] * Intracellular Signaling Peptides and Proteins [D12.776.476] * Intracellular Calcium-Sensing Proteins [ ... Intracellular Signaling Peptides and Proteins [D12.644.360] * Intracellular Calcium-Sensing Proteins [D12.644.360.372] * ... A family of intracellular calcium-sensing proteins found predominately in NEURONS and PHOTORECEPTOR CELLS. They contain EF HAND ...
Hippocalcin | Profiles RNS
Carrier Proteins [D12.776.157]. *Calcium-Binding Proteins [D12.776.157.125]. *Intracellular Calcium-Sensing Proteins [D12.776. ... A neuronal calcium-sensor protein that was initially found in the NEURONS of the HIPPOCAMPUS. It interacts with NEURONAL ... Heterogeneous N-terminal acylation of retinal proteins. Prog Lipid Res. 1999 Jan; 38(1):49-90. ... Intracellular Signaling Peptides and Proteins [D12.644.360]. *Intracellular Calcium-Sensing Proteins [D12.644.360.372] ...
Pediatric Hypoparathyroidism: Practice Essentials, Pathophysiology, Etiology
... or inappropriate regulations that result from the activated or antibody-stimulated calcium-sensing receptor (CaSR). These ... Mature PTH is an 84-amino acid protein. Production and secretion of PTH are regulated by a G protein-coupled calcium-sensing ... Unlike other protein hormones, its production and secretion are stimulated by decreased intracellular calcium concentrations, ... PHP Ia is due to loss-of-function mutations of the subunit of the G protein-coupled calcium-sensing receptor (Gsa). Mutations ...
Oxygen sensing and signal transduction in hypoxic pulmonary vasoconstriction | European Respiratory Society
... may induce intracellular calcium increase and subsequent contraction of PASMCs via direct or indirect interactions with protein ... and intracellular calcium mechanisms is still a source of debate. While intracellular calcium release has been shown to be ... Increased intracellular calcium inducing myosin light chain phosphorylation and contraction is achieved by calcium flow via ... Additionally, intracellular calcium release from RyR-sensitive calcium stores may contribute to HPV and activate store-operated ...
About Us
... biophysics and electrophysiology to understand how the intra cellular calcium sensing protein "Calmodulin" senses changes in ... Allen has been studying the protein-protein interactions in skeletal muscle excitation contraction coupling to discovery the ... specifically in the area of calcium-binding proteins. ... calcium concentration and modifies protein-protein interactions ... a structural biologist that utilizes a multi-disciplinary approach to understand how calcium modifies the function of proteins ...
Frontiers | Mechanistic insights into the role of calcium in the allosteric regulation of the calmodulin-regulated death...
Ca2+/CaM binds to the death-associated protein kinase 1 (DAPK1) to regulate intracellular signaling pathways. However, how the ... Ca2+-binding protein calmodulin (CaM) serves as a primary effector of calcium function. Ca2+/CaM binds to the death-associated ... Ca2+-binding protein calmodulin (CaM) serves as a primary effector of calcium function. ... protein kinase 1 (DAPK1) to regulate intracellular signaling pathways. However, the mechanism underlying the influence of Ca2+ ...
Pediatric Hypoparathyroidism: Practice Essentials, Pathophysiology, Etiology
... or inappropriate regulations that result from the activated or antibody-stimulated calcium-sensing receptor (CaSR). These ... Mature PTH is an 84-amino acid protein. Production and secretion of PTH are regulated by a G protein-coupled calcium-sensing ... Unlike other protein hormones, its production and secretion are stimulated by decreased intracellular calcium concentrations, ... PHP Ia is due to loss-of-function mutations of the subunit of the G protein-coupled calcium-sensing receptor (Gsa). Mutations ...
Activation of endogenous deltaF508 cystic fibrosis transmembrane conductance regulator by phosphodiesterase inhibition
... exhibit residual chloride channel activity that can be stimulated by agonists of the adenylate cyclase/protein kinase A pathway ... permeability is diminished by protein kinase A inhibitors and is not mediated by an increase in intracellular calcium ... Preincubation of CF-T43 cells with CFTR anti-sense oligonucleotides prevented an increase in 36Cl- efflux in response to beta- ... These data indicate that endogenous levels of deltaF508 protein can be stimulated to increase 36Cl- permeability in airway ...
Estilbenos
... are an important family of plant calcium sensor proteins that sense and decode changes in the intracellular calcium ... Involvement of the Calmodulin-like Protein Gene VaCML92 in Grapevine Abiotic Stress Response and Stilbene Production. ... Moreover, it elevated the mitochondrial membrane potential, decreased the gene and protein expression of Caspase-3 and Bax, and ... the western blot technique was used to analyze the effect of lipDMU-212 and FSH treatments on CYP11A1 and HSD3B1 protein levels ...
DeCS
Inhibitor of Growth Protein 1 * Intracellular Calcium-Sensing Proteins [D12.644.360.372] Intracellular Calcium-Sensing Proteins ... Inhibitor of Growth Protein 1 * Intracellular Calcium-Sensing Proteins [D12.776.476.387] Intracellular Calcium-Sensing Proteins ... One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protein in the ENDOPLASMIC ... One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protein in the ENDOPLASMIC ...
AMP-Activated Protein Kinases | Profiles RNS
I-kappa B Proteins. *Interleukin-1 Receptor-Associated Kinases. *Intracellular Calcium-Sensing Proteins ... Intracellular signaling protein kinases that play a signaling role in the regulation of cellular energy metabolism. Their ... Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]. *AMP-Activated Protein Kinases [D08.811.913.696.620.682.700.085 ... AMP-Activated Protein Kinase beta Subunits*AMP-Activated Protein Kinase beta Subunits ...
Mitogen-Activated Protein Kinase Phosphatases | Profiles RNS
I-kappa B Proteins. *Interleukin-1 Receptor-Associated Kinases. *Intracellular Calcium-Sensing Proteins ... Mitogen-Activated Protein Kinase Phosphatases*Mitogen-Activated Protein Kinase Phosphatases. *Mitogen Activated Protein Kinase ... "Mitogen-Activated Protein Kinase Phosphatases" is a descriptor in the National Library of Medicines controlled vocabulary ... A subcategory of phosphohydrolases that are specific for MITOGEN-ACTIVATED PROTEIN KINASES. They play a role in the ...
Context-dependent reversal of odorant preference is driven by inversion of the response in a single sensory neuron type | PLOS...
... revealing that context-dependent engagement of distinct intracellular signaling pathways within a single sensory neuron type is ... via heterotrimeric G proteins (Fig 3A) [26]. Reduced intracellular cGMP levels closes cGMP-gated channels, inhibits calcium ... To assess the extent to which saturation with 1 AWC-sensed odorant influences the response to a pulse of a second AWC-sensed ... we next examined hexanol-evoked changes in intracellular calcium dynamics. Attractive odorants decrease intracellular calcium ...
MeSH Browser
Intracellular Calcium-Sensing Proteins [D12.644.360.372] * Mesothelin [D12.644.360.410] * Methyl-Accepting Chemotaxis Proteins ... Amino Acids, Peptides, and Proteins [D12] * Proteins [D12.776] * Intracellular Signaling Peptides and Proteins [D12.776.476] * ... CDKI Proteins CIP-KIP CDKI Proteins CIP-KIP CKI Proteins CIP-KIP Cyclin-Dependent Kinase Inhibitors CKI Proteins Cyclin-Kinase ... Amino Acids, Peptides, and Proteins [D12] * Proteins [D12.776] * Neoplasm Proteins [D12.776.624] * Tumor Suppressor Proteins [ ...
Bone | 0013 | SFEBES2007 | Society for Endocrinology BES | Endocrine Abstracts
Ligand binding by the calcium-sensing receptor (CaSR), which belongs to family C of the G-protein coupled receptor super-family ... activates the phospholipase C-inositol triphosphate pathway and leads to an increase in intracellular calcium. CaSR ... Characterisation of 25 calcium-sensing receptor mutations in disorders of calcium homeostasis. Christie Paul , Curley Alan , ... Calcium-containing renal stones, which affect 7% of adults, may be associated with endocrine and metabolic disorders that ...
Calsequestrin | Profiles RNS
Calcium-Binding Proteins. *Annexins. *Calbindins. *Calsequestrin. *Fetuins. *Intracellular Calcium-Sensing Proteins. *Myosin ... Acidic protein found in SARCOPLASMIC RETICULUM that binds calcium to the extent of 700-900 nmoles/mg. It plays the role of ... In vivo, cardiac-specific knockdown of a target protein, malic enzyme-1, in rat via adenoviral delivery of DNA for non-native ...
DeCS
Inhibitor of Growth Protein 1 * Intracellular Calcium-Sensing Proteins [D12.644.360.372] Intracellular Calcium-Sensing Proteins ... PSD 95 Protein PSD-95 Protein PSD95 Protein Postsynaptic Density Protein 95 SAP 90 Protein SAP-90 Protein SAP90 Protein Synapse ... PSD 95 Protein. PSD-95 Protein. PSD95 Protein. Postsynaptic Density Protein 95. SAP 90 Protein. SAP-90 Protein. SAP90 Protein. ... Disks Large Homolog 4 Protein - Preferred Concept UI. M000632224. Scope note. A neuronal protein consisting of three PDZ ...
Mucin-4 | Profiles RNS
I-kappa B Proteins. *Interleukin-1 Receptor-Associated Kinases. *Intracellular Calcium-Sensing Proteins ... Mucin-4 may play a role in regulating cellular adhesion and in cell surface signaling from the ERBB-2 RECEPTOR PROTEIN-TYROSINE ... The alpha and beta chains result from the proteolytic cleavage of a precursor protein. ...
Class I Phosphatidylinositol 3-Kinases | Profiles RNS
Pediatric Hypoparathyroidism: Background, Pathophysiology, Epidemiology
... or inappropriate regulations that result from the activated or antibody-stimulated calcium-sensing receptor (CaSR). These ... Mature PTH is an 84-amino acid protein. Production and secretion of PTH are regulated by a G protein-coupled calcium-sensing ... Unlike other protein hormones, its production and secretion are stimulated by decreased intracellular calcium concentrations, ... The calcium-sensing receptor: a window into the physiology and pathophysiology of mineral ion metabolism [published erratum ...
Calcium-sensing receptor residues with loss- and gain-of-function mutations are located in regions of conformational change and...
... is a homodimeric G-protein-coupled receptor that signals via intracellular calcium (Ca2+i) mobilisation and phosphorylation of ... extracellular signal-regulated kinase 1/2 (ERK) to regulate extracellular calcium (Ca2+e) homeostasis. The central importance ... The calcium-sensing receptor (CaSR) is a homodimeric G-protein-coupled receptor that signals via intracellular calcium (Ca2+i) ... Calcium-sensing receptor residues with loss- and gain-of-function mutations are located in regions of conformational change and ...
MeSH Browser
Intracellular Calcium-Sensing Proteins [D12.776.476.387] * Mesothelin [D12.776.476.410] * Methyl-Accepting Chemotaxis Proteins ... Amino Acids, Peptides, and Proteins [D12] * Proteins [D12.776] * Intracellular Signaling Peptides and Proteins [D12.776.476] * ... Tumor Necrosis Factor alpha-Induced Protein 3 [D12.776.476.938] * Tumor Protein, Translationally-Controlled 1 [D12.776.476.941] ... Phosphatidylethanolamine Binding Protein [D12.776.476.555] * Phosphatidylinositol 3-Kinases [D12.776.476.556] * ...
Cyclins | Profiles RNS
Inhibitor of Growth Protein 1. *Interleukin-1 Receptor-Associated Kinases. *Intracellular Calcium-Sensing Proteins ... F-box protein specificity for g1 cyclins is dictated by subcellular localization. PLoS Genet. 2012; 8(7):e1002851. ... A large family of regulatory proteins that function as accessory subunits to a variety of CYCLIN-DEPENDENT KINASES. They ... CDK and MAPK Synergistically Regulate Signaling Dynamics via a Shared Multi-site Phosphorylation Region on the Scaffold Protein ...
Pharos : Target Details - P0DP25
This gene encodes a member of a family of proteins that binds calcium and functions as a enzymatic co-factor. Activity of this ... Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together ... protein is important in the regulation of the cell cycle and cytokinesis. Multiple alternatively spliced transcript variants ... Protein / Calcium-binding Protein. / Intracellular Calcium-sensing Protein. / Calmodulin. / Calmodulin-3. DTO Classes. Protein ...
Plus it
Voltage-sensing calcium ion channels, and the CaV2 channel in particular, play an integral role in regulating synaptic ... Protein assembly is a complex and regulated process; membrane-resident proteins typically stay in the endoplasmic reticulum (ER ... one intracellular and one extracellular, were known to play a part in the channels function, but whether they also aid in ... Watching Calcium Channel Subunit Trafficking in C. elegans. Kelly H. Oh, Ame Xiong, Jun-yong Choe, Janet E. Richmond, and ...
Aquaporin Membrane Channels in Oxidative Stress, Cell Signaling, and Aging: Recent Advances and Research Trends
This review focuses on emerging topics encompassing the functional involvement of aquaporin channel proteins (AQPs) and ... While ROS-dependent modifications are fundamental in transducing intracellular signals controlling pleiotropic functions, ... measured in cells displaying low intracellular calcium concentration, secondary to the expression of the calcium-sensing ... 3. Aquaporins, Membrane Channel Proteins of Pleiotropic Relevance. Aquaporins (AQPs) are channel proteins widely present in ...