Cell Cycle Regulation of Myosin-V by Calcium/Calmodulin-Dependent Protein Kinase II | Science
Wild-type and mutant proteins are listed above each pair of lanes, and the treatment with either mitotic (M) or interphase (I) ... Half a milligram of GST-myc-MGT bound to glutathione-agarose beads was labeled in 100 μl of either mitotic or interphase ... Myosin-V-driven transport of melanosomes is inhibited by their incubation in mitotic, but not interphase, Xenopus egg extract ... MGT bound to melanosomes (C) and was retained after treatment with interphase egg extract (I) but was released after treatment ...
Clinical Resistance to STI-571 Cancer Therapy Caused by BCR-ABL Gene Mutation or Amplification | Science
Interphase and metaphase cells were prepared (37) and examined with Locus Specific Identifier BCR-ABL dual color translocation ... Bar, 10 μm.) (B) BCR-ABL FISH analyses of interphase nuclei from blast crisis patient M14 before, during, and after removal ... A) BCR-ABL FISH analyses of interphase nuclei from blast crisis patient M13 before and during STI-571 therapy. Nuclei are ... Multiple copies of the BCR-ABL gene were detected in interphase nuclei in three (two myeloid blast crisis, one lymphoid blast ...
Sustained Microtubule Treadmilling in Arabidopsis Cortical Arrays | Science
... interphase microtubules show a progressive change in organization after cell division. Unlike interphase arrays in animal or ... 3, A and B) (movie S5). This recovery time is faster than that measured in animal interphase arrays by a factor of ∼4 (19, 20 ... Thus, the majority of new microtubules in mature interphase arrays were likely created at the cell cortex and did not come from ... Further, the discovery of dynamic instability as the dominant mode of dynamic behavior in the Arabidopsis interphase arrays ...
Control of Stem Cell Self-Renewal in Drosophila Spermatogenesis by JAK-STAT Signaling | Science
3D, arrowhead). This was confirmed using the late interphase marker Anillin, which strongly stains SSCs but decreases as cyst ... Anillin marks all interphase nuclei in the wild type, particularly SSC nuclei (small arrowheads) near the hub (outlined). Their ...