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*  Differential effects of BMP signaling on parvalbumin and somatostatin interneuron differentiation. - Semantic Scholar
Treatment of cortical cultures containing interneuron precursors is sufficient to generate PV(+) interneurons prematurely and ... interneurons. PV(+) interneurons in the cortex express BMP type I receptors and a subpopulation displays activated BMP ... However, PV (also known as PVALB) is not expressed by interneurons until the second postnatal week after reaching the cortex, ... Furthermore, overexpression of BMP4 in vivo increases the number of interneurons expressing PV, with a reduction in the number ...
  https://www.semanticscholar.org/paper/Differential-effects-of-BMP-signaling-on-parvalbum-Mukhopadhyay-Mcguire/628e718270d2446b07ce83de5cf0dbf7c67b5f7c
*  Brain State Dependent Postinhibitory Rebound in Entorhinal Cortex Interneurons | Journal of Neuroscience
We found interneuron-interneuron pairs that displayed PIR during theta state but displayed only inhibition during SO. Typical ... Some target neurons that display rebound upon inhibition from some interneurons (e.g., interneurons number 18 and 30 onto ... PIR is mostly present at interneuron-interneuron connections. By definition, PIR corresponds to an inhibition-excitation ... in the ISI histograms of a theta phase-modulated interneuron (E, G) and a theta phase-unmodulated interneuron (F, H), during ...
  http://www.jneurosci.org/content/32/19/6501
*  Lake Forest College Publications - Steven Galovich Memorial Student Symposium: Repeated Drug Exposure Disrupts Rat Hippocampal...
I found developmental disregulation of GABA interneurons to cocaine and a glutamate agonist, but not to a marijuana-mimic. This ... Recent findings indicate that these drugs disrupt GABA interneurons in the maturing PFC, but effects on hippocampus are unknown ... For my thesis, I investigated three such drugs for effects on hippocampal GABA interneurons in adolescent rats. ... GABA interneurons mediate maturation of the prefrontal cortex (PFC) and hippocampus during adolescence. ...
  https://publications.lakeforest.edu/gss/gss2013/program/19/
*  Plus it
... and PV-positive interneurons in the rat BLA. As observed in the mouse, GAD staining revealed classical local interneurons, ... paracapsular interneurons were immunopositive only for GAD. To determine whether similar populations of interneurons are ... One population of classical interneurons was scattered throughout the BLA, was immunopositive for typical interneuron markers ... 2B). These findings suggest that, as observed in the mouse BLA, pcs and local GABAergic interneurons in the rat BLA activate ...
  http://jpet.aspetjournals.org/content/324/1/251
*  "The Continuing Case for the Renshaw Cell" by Francisco J. Alvarez and Robert E.W. Fyffe
... making them a uniquely well-defined class of spinal interneuron. Recent work has revealed novel ways to identify Renshaw cells ... making them a uniquely well-defined class of spinal interneuron. Recent work has revealed novel ways to identify Renshaw cells ...
  https://corescholar.libraries.wright.edu/ncbp/354/
*  ModelDB: Synchronicity of fast-spiking interneurons balances medium-spiny neurons (Damodaran et al. 2014)
Neostriatum spiny direct pathway neuron; Neostriatum spiny indirect pathway neuron; Neostriatum fast spiking interneuron; ... 1 . Damodaran S, Evans RC, Blackwell KT (2014) Synchronized firing of fast-spiking interneurons is critical to maintain ... Synchronicity of fast-spiking interneurons balances medium-spiny neurons (Damodaran et al. 2014). ...
  https://senselab.med.yale.edu/ModelDB/ShowModel.cshtml?model=156260&file=%2Fstriatalnetwork%2FUtilities%2F
*  The Generation of Cortical Interneurons : Jasper's Basic Mechanisms of the Epilepsies - oi
... it is likely that they have roles in controlling interneuron function and/or survival, such as Dlx1.36 As interneuron defects ... because many of the transcription factors that regulate early interneuron development are expressed in mature interneurons (e.g ... Most, if not all, mouse pallial interneurons are derived from three progenitor regions in the embryonic subpallium: MGE, CGE, ... Most, if not all, mouse pallial interneurons are derived from three progenitor regions in the embryonic subpallium: MGE, CGE, ...
  http://oxfordindex.oup.com/view/10.1093/med/9780199746545.003.0061
*  Epigenome Mapping in Cortical Interneurons - Schahram Akbarian
2015) Interneuron epigenomes during the critical period of cortical plasticity: Implications for schizophrenia. Neurobiol Learn ... Epigenome Mapping in Cortical Interneurons Akbarian, Schahram University of Massachusetts Medical School Worcester, Worcester, ... These GABA related gene expression deficits include distinct cell types such as the class of fast spiking interneurons commonly ... Epigenome Mapping in Cortical Interneurons. Akbarian, Schahram / Icahn School of Medicine at Mount Sinai. $369,540. ...
  http://grantome.com/grant/NIH/R01-MH093332-02
*  Neuronal Networks of Movement : Slc10a4 as a Modulator & Dmrt3 as a Gait-keeper
The transcription factor encoded by Dmrt3 was found to be expressed in a population of inhibitory commissural interneurons ... Locomotion in mammals relies on a central pattern-generating circuitry of spinal interneurons established during development ... Commissural Inhibitory Interneuron National Category Neurosciences Research subject. Neuroscience Identifiers. URN: urn:nbn:se: ... much remains to be revealed regarding the identity and function of specific interneuron cell types and how neuromodulation tune ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:745033
*  NeuroElectro :: Article
Barrel Cortex Layer IV Fast-Spiking Interneuron resting membrane potential (mV) -64.5 (118) -64.5 (mV) Data Table. ... Barrel Cortex Layer IV Somatostatin Containing Interneuron resting membrane potential (mV) -64.0 (30) -64.0 (mV) Data Table. ... Barrel Cortex Layer IV Fast-Spiking Interneuron input resistance (MΩ) 68.0 (118) 68.0 (MΩ) Data Table. ... Barrel Cortex Layer IV Fast-Spiking Interneuron spike half-width (ms) 0.21 (118) 0.21 (ms) Data Table. ...
  https://neuroelectro.org/article/14309/
*  neuron-glia interactions - Dwight Bergles Laboratory
Interneurons are critical for proper neural network function and can activate Ca2+ signaling in astrocytes. However, the impact ... Therefore, astrocytes decode interneuron activity and transform inhibitory into excitatory signals, contributing to the ... Stimulation in stratum oriens reliably elicited a slow mGluR1-mediated current in O-LM interneurons if they were briefly ... Transporter-dependent potentiation of mGluR1 EPSCs led to a dramatic increase in interneuron firing and enhanced inhibition of ...
  http://bergleslab.com/index.php/tag/neuron-glia-interactions/
*  "Target Selection of Proprioceptive and Motor Axon Synapses on Neonatal" by Valerie C. Siembab, Courtney A. Smith et al.
Some Ia inhibitory interneurons (IaINs) and all Renshaw cells (RCs) derive from embryonic V1 interneurons; however, in adult ... Thus, motor, proprioceptive, and even some interneuron inputs are biased toward specific subtypes of V1-interneurons. Postnatal ... V1-interneurons were labeled using genetically encoded lineage markers in mice. The results show that although neonatal V1- ... Alternatively, specific inputs might precisely connect only with predefined groups of V1 interneurons. To test these hypotheses ...
  https://corescholar.libraries.wright.edu/ncbp/540/
*  A developmental cell-type switch in cortical interneurons leads to a selective defect in cortical oscillations - CSHL...
We use a genetic cell fate switch to delete both PV+ and SST+ interneurons selectively in cortical layers 2-4 without ... A developmental cell-type switch in cortical interneurons leads to a selective defect in cortical oscillations ... The cellular diversity of interneurons in the neocortex is thought to reflect subtype-specific roles of cortical inhibition. ... Here we ask whether perturbations to two subtypes-parvalbumin-positive (PV+) and somatostatin-positive (SST+) interneurons-can ...
  http://repository.cshl.edu/30900/
*  Role of ionotropic glutamate receptors in long-term potentiation in rat hippocampal CA1 oriens-lacunosum moleculare...
Because interneuron diversity potentially conceals simple rules underlying different forms of plasticity, we focus on ... We show that anti-Hebbian LTP in O-LM interneurons has consistent induction and expression properties, and is prevented by ... Although both AMPA and kainate receptors are expressed in hippocampal interneurons, their relative roles in anti-Hebbian LTP ... Some interneurons of the hippocampus exhibit NMDA receptor-independent long-term potentiation (LTP) that is induced by ...
  https://pharm.ox.ac.uk/publications/185115
*  interneuron - Everything2.com
The interneurons constitute one of the three basic classes of neuron,neurons. They receive input only from neurons, either ... Interneurons make up all of the brain and most of the spinal cord, and number close to a hundred billion by some estimates. ... The interneurons constitute one of the three basic classes of neurons. They receive input only from neurons, either sensory ... The interneurons that make up the brain's cerebral cortex alone include pyramidal, spiny stellate, chandelier,and basket ...
  https://everything2.com/title/interneuron
*  Interneuron Issue 4.2 by theinterneuron - issuu
Title: Interneuron Issue 4.2, Author: theinterneuron, Name: Interneuron Issue 4.2, Length: 23 pages, Page: 1, Published: 2017- ... GET INVOLVED! Interneuron is always looking for contributors! If you are interested in joining us as a writer, artist, or ... Send us an email: interneuron.utoronto@gmail.com Images from http://icons.iconarchive.com/icon s/custom-icon-design/flatastic- ...
  https://issuu.com/theinterneuron/docs/interneuron_issue_4.2
*  Interneurons find their way to the striatum
... 11.06.2015. Researchers from the MRC Centre for Developmental Neurobiology (MRC ... MGE-derived interneurons are shown expressing EphB3 (red) and Nkx2-1 (green) migrating to the striatum. ... While most research studies have focused on the migration of interneurons to the cortex, very little is known about the ... Both cortical and striatal interneurons can be attracted by Nrg1 sources present in the cerebral cortex and the striatum. ...
  http://www.innovations-report.com/html/reports/life-sciences/interneurons-find-their-way-to-the-striatum.html
*  Differentiation of V2a interneurons from human pluripotent stem cells | PNAS
V2a interneuron protocol specifically increases V2a interneuron population. (A) Timeline contrasting the motor neuron and V2a ... Single-cell RNAseq of V2a interneuron cultures. (A) tSNE plot of V2a interneuron cultures indicating seven clusters. (B) CHX10 ... V2a interneuron protocol robustly increases hPSC neurogenesis. (A) Gene expression throughout V2a interneuron differentiation ... Long-Term Culture Increases the Maturation Profile of V2a Interneurons.. To examine the maturation of V2a interneurons, ...
  https://www.pnas.org/content/114/19/4969
*  Nonspiking and Spiking Local Interneurons in the Locust | SpringerLink
... nonspiking interneurons) (for reviews, see Roberts and Bush, 1981), the question of why such neurons should exist... ... Since the discovery of interneurons that normally do not produce action potentials ( ... Since the discovery of interneurons that normally do not produce action potentials (nonspiking interneurons) (for reviews, see ... Burrows, M. and Siegler, M. V. S., 1982, Spiking local interneurons mediate local reflexes, Science 217:650-652.PubMedCrossRef ...
  https://link.springer.com/chapter/10.1007/978-1-4757-5858-0_7
*  Hyperactivity is Associated with Decreased Numbers of Interneurons
... 14.05.2008. A new study published in Biological Psychiatry ... A decreased number of these same interneurons is "one of the most consistent findings in schizophrenia and psychotic disorders ... hyperactivity that is correlated with a lack of parvalbumin-positive and somatostatin-positive inhibitory interneurons in the ...
  http://www.innovations-report.com/hrml/reports/studies/report-109937.html
*  Novel markers for OLM interneurons in the hippocampus
interneuron, OLM, somatostatin, hippocampus, Chrna2 National Category Neurosciences Identifiers. URN: urn:nbn:se:uu:diva-259200 ... In this thesis I present compelling in vitro and in vivo evidence that a subpopulation of OLM interneurons (defined by the ... 1. On the Mechanisms Behind Hippocampal Theta Oscillations: The role of OLMα2 interneurons. Open this publication in new window ... hippocampus, interneuron, optogenetics, theta oscillations, anxiety National Category Neurosciences Identifiers. urn:nbn:se:uu: ...
  http://www.diva-portal.org/smash/record.jsf?pid=diva2:843720
*  Transplanted interneurons can help reduce fear in mice | EurekAlert! Science News
Scientists in China are reporting that by transplanting mouse embryonic interneurons into the brains of mice and combining that ... "We also need to determine the exact subtype of transplanted interneurons and the exact subregion in the amygdala that are ... "We found that although the transplanted interneurons did not alter the formation of fear memories, they reduced recovery and ... Scientists in China are reporting that by transplanting mouse embryonic interneurons into the brains of mice and combining that ...
  https://www.eurekalert.org/pub_releases/2016-12/cp-tic120116.php
*  Wide Dispersion and Diversity of Clonally Related Inhibitory Interneurons. - PubMed - NCBI
... we find that clonally related interneurons can be widely dispersed while unrelated interneurons can be closely clustered. These ... Wide Dispersion and Diversity of Clonally Related Inhibitory Interneurons.. Harwell CC1, Fuentealba LC2, Gonzalez-Cerrillo A3, ... The role of lineage in the organization and circuitry of interneurons is still not well understood. Utilizing a combination of ... which divide symmetrically to produce pairs of newborn interneurons. The newborn neurons must then migrate tangentially to ...
  https://www.ncbi.nlm.nih.gov/pubmed/26299474
*  Interneurons from Embryonic Development to Cell-Based Therapy | Science
Interneurons Reach Far and Wide. Interneurons in the brain have been garnering increasing attention. Southwell et al. (10.1126/ ... Cortical interneurons are a heterogeneous population, and little is known about how distinct subtypes of interneurons function ... It is unknown how transplanted interneurons modify disease phenotypes. While transplanted interneurons likely exert therapeutic ... and even some sorts of chronic pain either involve interneurons or may respond to transplanted interneurons. ...
  http://science.sciencemag.org/content/344/6180/1240622
*  INTERNEURON FILES FOR OFFERING | BioWorld
BioWorld Online is the news service of record for the biotechnology industry and is updated every business morning. BioWorld Online will keep you up to date on all of the industry's business, science and regulatory news -- mergers and collaborations, FDA hearings and results, breakthroughs in research and much more.
  http://www.bioworld.com/content/interneuron-files-offering