Interleukin 7 - Wikipedia
1994). "Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor". Science. 262 (5141): 1877-80 ... Interleukin 7 (IL-7) is a protein that in humans is encoded by the IL7 gene. IL-7 is a hematopoietic growth factor secreted by ... September 1993). "Interleukin 7 is produced by murine and human keratinocytes". J. Exp. Med. 178 (3): 1109-14. doi:10.1084/jem. ... Muegge K, Vila MP, Durum SK (July 1993). "Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene". ...
Plasma interleukin-3 (IL-3) and IL-7 concentrations in children with homozygous beta-thalassemia
Plasma levels of IL-3 and IL-7 were studied in 23 patients with homozygous beta-thalassemia in order to determine whether these ... No significant difference was found in plasma IL-7 conce … ... Plasma interleukin-3 (IL-3) and IL-7 concentrations in children ... 1997 Dec;43(6):366-7. doi: 10.1093/tropej/43.6.366. Authors N Kutukculer 1 , C Vergin, N Cetingul, K Kavakli, S Caglayan, S ... Plasma levels of IL-3 and IL-7 were studied in 23 patients with homozygous beta-thalassemia in order to determine whether these ...
IL7 Human Protein Recombinant | Interleukin-7 | ProSpec
IL-7 Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight range of 19-30kDa due to ... IL-7 is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a ... IL-7 Human Recombinant produced in HEK cells is a glycosylated monomer, having a molecular weight range of 19-30kDa due to ... Lyophilized IL-7 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution ...
2019 Session | (2015) Enhancing Tumor Directed T Cells with an Interleukin-7 Signal Modulator · ASPHO
IL7RA, interleukin 7 receptor - Creative BioMart
Interleukin-7/Interferon axis drives T-cell and salivary gland epithelial cell interactions in Sjögren's syndrome. | Quanterix
Interleukin-7/Interferon axis drives T-cell and salivary gland epithelial cell interactions in Sjögrens syndrome.. ... IL‐7 was secreted by SGECs stimulated with type 1 or type 2 IFN and, in turn, activate T cells that secrete type 2 IFN. An anti ... IL‐7 serum level was increased in pSS patients versus controls and was associated with B‐cell biomarkers. IL7R expression was ... The aim of this work was to study the interactions between SGECs and T cells in pSS and the role of the IL‐7/IFN axis. ...
Interleukin 7 Receptor - Creative Biolabs
... including interleukin-2, -4, -9, and -15. Interleukin-7 receptor is expressed on various cell types, including naive and memory ... Interleukin 7 Receptor. Product list The interleukin-7 receptor is a protein found on the surface of cells. It is made up of ... interleukin-7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various ...
IL7Rbase: Interleukin-7 receptor α deficiency | Publications
Characterization of a novel nonsense mutation in the interleukin-7 receptor alpha gene in a Korean patient with severe combined ... A partial deficiency of interleukin-7R alpha is sufficient to abrogate T-cell development and cause severe combined ... Blood 2000(8): 2803-7 [PubMed abstract]. 1998. * Defective IL7R expression in T(-)B(+)NK(+) severe combined immunodeficiency.. ... Variation registry for Interleukin-7 receptor α deficiency Select database by name. ADAbase. AICDAbase. AIREbase. AK2base. ...
Interleukin 23 - wikidoc
Sedgwick JD (Feb 2003). "Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the ... Interleukin-23 (IL-23) is a heterodimeric cytokine composed of an IL12B (IL-12p40) subunit (that is shared with IL12) and the ... 110 (4): 493-7. doi:10.1172/JCI15751. PMC 150420. PMID 12189243.. *↑ Cua DJ; Sherlock J; Chen Y; Murphy CA; Joyce B; Seymour B ... "Interleukin-23 drives innate and T cell-mediated intestinal inflammation". Journal of Experimental Medicine. 203 (11): 2473-83 ...
STIMULATION OF HUMAN AND MURINE THYMOCYTE PROLIFERATION BY INTERLEUKIN-7 - Immunology
The role of interleukin-7 during haematopoiesis<...
The role of interleukin-7 during haematopoiesis. / Brown, Geoffrey.. Advances in Medicine and Biology. Nova Science Publishers ... Brown, G. (Accepted/In press). The role of interleukin-7 during haematopoiesis. In Advances in Medicine and Biology Nova ... The role of interleukin-7 during haematopoiesis. In Advances in Medicine and Biology. Nova Science Publishers, Inc. 2018 ... The role of interleukin-7 during haematopoiesis. Advances in Medicine and Biology. Nova Science Publishers, Inc., 2018. ...
Severe combined immunodeficiency (SCID) | Immune Deficiency Foundation
Interleukin 7 receptor (IL7R) deficiency SCID. The fourth most common type of SCID, which accounts for less than 10% of cases, ... The most common form of SCID, affecting nearly 30% of all cases, is due to a variant in the interleukin 2 receptor gamma (IL2RG ... is interleukin 7 receptor (IL7R) deficiency. In this type of SCID, the gene variant prevents the creation of the IL7R chain, ...
MedlinePlus: Genes: I
Stem cell factor and interleukin-7 synergize to enhance early myelopoiesis in vitro. - Radcliffe Department of Medicine
IL-7 has been shown to synergize with stem cell factor (SCF) to provide a potent growth stimulus for pre-B cells. However, the ... Interleukin-7 (IL-7) has been shown to be a critical factor in murine lymphoid development. It stimulates pre-B cells to divide ... rhIL-7 alone had no proliferative effect on Lin-Sca1+ cells, but in a dose-dependent manner directly enhanced rrSCF-induced ... In the present study, the effects of recombinant rat (rr) SCF and recombinant human (rh) IL-7 on primitive murine bone marrow ...
Thyroxine: Reference Range, Interpretation, Collection and Panels
Continuous interleukin-6 application in vivo via macroencapsulation of interleukin-6-expressing COS-7 cells induces massive...
Cellular localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain.. Schobitz B, de Kloet ER, Sutanto W, ... Localization of interleukin 6 mRNA and interleukin 6 receptor mRNA in rat brain.. Schobitz B, Voorhuis DA, De Kloet ER., ... Expression of interleukin-6 (IL-6) and interleukin-6 receptor (IL-6R) mRNAs in rat brain during postnatal development.. Gadient ... Continuous interleukin-6 application in vivo via macroencapsulation of interleukin-6-expressing COS-7 cells induces massive ...
Interleukin 7 and interleukin 4 stimulate human thymocyte growth through distinct mechanisms. - The Kennedy Institute of...
We have investigated the effects of interleukin 4 (IL-4) and interleukin 7 (IL-7) on human thymocyte proliferation. Although ... Proliferation induced with IL-7 plus PHA, but not that induced by IL-7 alone, could be blocked by this treatment. In contrast, ... Our findings show that both IL-7 and IL-4 can act as growth factors for human thymocytes, and that these cytokines stimulate ... maximal proliferation was dependent upon the presence of the mitogen phytohaemagglutinin (PHA), IL-7 alone stimulated thymocyte ...
Cytomegalovirus infection induces the accumulation of short-lived, multifunctional CD4(+) CD45RA(+) CD27(-) T cells: the...
The serum factor from patients with ulcerative colitis that induces T cell proliferation in the mouse thymus is interleukin-7<...
Since interleukin-7 is a crucial cytokine for proliferation and differentiation of T cells in the thymus, the present study ... Since interleukin-7 is a crucial cytokine for proliferation and differentiation of T cells in the thymus, the present study ... Since interleukin-7 is a crucial cytokine for proliferation and differentiation of T cells in the thymus, the present study ... Since interleukin-7 is a crucial cytokine for proliferation and differentiation of T cells in the thymus, the present study ...
Two genes encoding immune-regulatory molecules (LAG3 and IL7R) confer susceptibility to multiple sclerosis
Receptors, Interleukin-7 / genetics* Substances * Antigens, CD * Receptors, Interleukin-7 * Lymphocyte Activation Gene 3 ...
25-hydroxycholesterol, 7β-hydroxycholesterol and 7-ketocholesterol upregulate interleukin-8 expression independently of Toll...
Each oxysterol stimulated secretion of the inflammatory chemokine interleukin-8 (IL-8), but not I?B degradation or tumour ... Each oxysterol stimulated secretion of the inflammatory chemokine interleukin-8 (IL-8), but not I?B degradation or tumour ... Each oxysterol stimulated secretion of the inflammatory chemokine interleukin-8 (IL-8), but not I?B degradation or tumour ... Each oxysterol stimulated secretion of the inflammatory chemokine interleukin-8 (IL-8), but not I?B degradation or tumour ...
Puppet masters of B-cell progenitor acute lymphoblasticleukemia: The preB cell receptor and the interleukin 7 receptor α -...
Puppet masters of B-cell progenitor acute lymphoblasticleukemia: The preB cell receptor and the interleukin 7 receptor α ... Puppet masters of B-cell progenitor acute lymphoblasticleukemia: The preB cell receptor and the interleukin 7 receptor α. ... Two signaling pathways viathe preB cell receptor (preBCR) and the interleukin 7 receptorα(IL-7Rα) chain govern thebalance ...
WHO EMRO | Interleukins 12 and 13 levels among beta-thalassaemia major patients | Volume 19, issue 2 | EMHJ volume 19, 2013
Interleukins 12 and 13 levels among beta-thalassaemia major patients ... Increased plasma levels of interleukin-6 and interleukin-8 in beta-thalassaemia major. Haematologia, 2001, 31:237-244. ... Increased plasma levels of interleukin-6 and interleukin-8 in beta-thalassaemia major. Haematologia, 2001, 31:237-244. ... Plasma interleukin-3 (IL-3) and IL-7 concentrations in children with homozygous beta-thalassemia. Journal of Tropical ...
Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes | Diabetes Care | American Diabetes...
Pancreatic β-cell IL-1 expression is increased and interleukin-1 receptor ... Interleukin (IL)-1 impairs insulin secretion and induces β-cell apoptosis. ... Sustained Effects of Interleukin-1 Receptor Antagonist Treatment in Type 2 Diabetes Claus M. Larsen, MD; Claus M. Larsen, MD ... Interleukin (IL)-1 impairs insulin secretion and induces β-cell apoptosis. Pancreatic β-cell IL-1 expression is increased and ...
Frontiers | Immunological Feature and Transcriptional Signaling of Ly6C Monocyte Subsets From Transcriptome Analysis in Control...
Interleukin-6 induces monocyte chemotactic protein-1 in peripheral blood mononuclear cells and in the U937 cell line. Blood ( ... Angiotensin II hypertension is attenuated in interleukin-6 knockout mice. Am J Physiol Heart Circulatory Physiol (2006) 290: ... Lack of T-bet reduces monocytic interleukin-12 formation and accelerates thrombus resolution in deep vein thrombosis. Sci Rep ( ... interleukin)-1, IL-18, IL-15, and MCP (MC chemoattractant protein)-1 to contribute to systemic/tissue inflammation and T-cell ...
Cord blood stem cell‑derived Angptl7 ameliorates the severity of bronchopulmonary dysplasia via anti‑inflammatory and...
The concentrations of interleukin‑6 and monocyte chemoattractant protein‑1 were negatively correlated with cord blood Angptl7 ... interleukin-6 (IL-6; pg/ml), and monocyte chemoattractant protein-1 (MCP-1; pg/ml) concentrations. A minimum of 5 µl serum was ... interleukin-6; MCP-1, monocyte chemoattractant protein-1; VEGF-A, vascular endothelial growth factor-A. ... 7).. Figure 7.. Concentrations of proinflammatory cytokines IL-6 and MCP-1 in serum as determined by ELISA. (a) MCP-1 and (b) ...
IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor | Nature...
We engineered CAR-T cells to express interleukin (IL)-7 and CCL19 (7 × 19 CAR-T cells), as these factors are essential for the ... In mice, 7 × 19 CAR-T cells achieved complete regression of pre-established solid tumors and prolonged mouse survival, with ... Depletion of recipient T cells before 7 × 19 CAR-T cell administration dampened the therapeutic effects of 7 × 19 CAR-T cell ... Following treatment of mice with 7 × 19 CAR-T cells, both recipient conventional T cells and administered CAR-T cells generated ...
Frontiers | Influence of the Circadian Timing System on Tacrolimus Pharmacokinetics and Pharmacodynamics After Kidney...
AKR1B10 | Cancer Genetics Web
MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.. Proc Natl Acad Sci U S A. 2019; 116(12 ... Melanoma differentiation-associated gene-7/interleukin-24 ( Related: Apoptosis MicroRNAs MITF Cancer Prevention and Risk ... Two breast cancer cell lines, MCF-7 (ERα-dependent) and MDA-MB-231 (ERα-independent) were examined. We found that DEHP impaired ... A zebrafish xenograft model confirmed the disruptive effect of DEHP on CPT-induced anti-growth of MCF-7 cells. In summary, DEHP ...
Interleukin-27 Ameliorates Atherosclerosis in ApoE-/- Mice through Regulatory T Cell Augmentation and Dendritic Cell Tolerance
Recent evidence indicated that interleukin (IL)-27 showed pleiotropic properties in immune diseases. However, precise ... Figure 7(a)). TGF-β (. vs , respectively; ), Foxp3 (. vs , respectively; ), and IL-10 (. vs , respectively; ) levels were ... In the groups modeling the progression of atherosclerosis (Figure 7(b)), TGF-β (. vs , respectively; ), Foxp3 (. vs , ... R. Zhu, H. Sun, K. Yu et al., "Interleukin-37 and dendritic cells treated with interleukin-37 plus troponin I ameliorate ...