Tyrosine kinase of the non-receptor type, involved in the interleukin-2 and interleukin-4 signaling pathway. Phosphorylates ... Liu B & Ren B MiR-1193 represses the proliferation and induces the apoptosis of interleukin-1ß-treated fibroblast-like ... synoviocytes via targeting JAK3. Int J Rheum Dis 23:1066-1075 (2020). PubMed: 32597556 ...
Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. ... Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF, LEP and other growth ... Dephosphorylation on tyrosine residues by PTPN2 negatively regulates IL6/interleukin-6 signaling. ...
... and multiple interleukins. Following stimulation with erythropoietin (EPO) during erythropoiesis, it is autophosphorylated and ...