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*  Patent US6451983 - Tumor necrosis factor antibodies - Google Patents
... characterization and comparison with the actions of interleukin 1," Proc. Natl. Acad. Sci. USA Medical Sciences 83:4533-4537. ... 23.. In a further preferred embodiment of the third aspect of the present invention the ligand binds to human TNF in the ... 23(4):441-450.. 17. Socher, S.H. et al. (Dec. 1987) "Antibodies against amino acids 1-15 tumor necrosis factor block its ... wherein the antibody binds to TNF-α such that the epitope defined by the topographic regions Ala22-Glu23-Gly24-Gln25-Leu26-Gln ...
  http://www.google.co.uk/patents/US6451983
*  Immobilization increases interleukin-6, but not tumour necrosis factor-a, release from the leg during exercise in humans -...
Immobilization increases interleukin-6, but not tumour necrosis factor-a, release from the leg during exercise in humans. * ... Data on interleukin-6 (IL-6) and tumour necrosis factor-a (TNF-a) release during acute exercise are not conclusive, and ... Exercise; Exercise Test; Femoral Vein; Humans; Immobilization; Interleukin-6; Leg; Male; Oxygen Consumption; Regional Blood ... Interleukin-6 release occurred after 15 min of exercise, and the release from the IM leg was significantly greater compared ...
  http://www.forskningsdatabasen.dk/catalog/236579463
*  Interleukin-23 - Interleukins (IL) | Sigma-Aldrich
USA Home > Product Directory > Cell Culture > Reagents and Supplements > Growth Factors and Cytokines > Interleukins (IL) > ... Interleukin-23 human IL-23, recombinant, expressed in HEK 293 cells, HumanKine®, suitable for cell culture * pricing ...
  https://www.sigmaaldrich.com/life-science/cell-culture/cell-culture-products.html?TablePage=122742832
*  interleukin 23, subunit alpha Protein Superfamily Detail
Term: interleukin 23, subunit alpha. ID: PIRSF038754 Mouse Protein Superfamily Annotations. Select one or more mouse PIRSF ...
  http://www.informatics.jax.org/vocab/pirsf/PIRSF038754
*  Interleukin 23 - Wikipedia
Interleukin-23 (IL-23) is a heterodimeric cytokine composed of an IL12B (IL-12p40) subunit (that is shared with IL12) and the ... Hue S, Ahern P, Buonocore S, Kullberg MC, Cua DJ, McKenzie BS, Powrie F, Maloy KJ (2006). "Interleukin-23 drives innate and T ... Sedgwick JD (Feb 2003). "Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the ... "Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12". Journal of Clinical Investigation. 110 ...
  https://en.wikipedia.org/wiki/Interleukin_23
*  Interleukin-23 receptor - Wikipedia
Interleukin 23 receptor is a type I cytokine receptor. IL23R is its human gene. The protein encoded by this gene is a subunit ... Borgiani P, Perricone C, Ciccacci C, Romano S, Novelli G, Biancone L, Petruzziello C, Pallone F (Sep 2007). "Interleukin-23R ... IL23R interleukin 23 receptor". Duerr RH, Taylor KD, Brant SR, Rioux JD, Silverberg MS, Daly MJ, et al. (Dec 2006). "A genome- ... "Analysis of interleukin-23 receptor (IL23R) gene polymorphisms in systemic lupus erythematosus". Tissue Antigens. 70 (3): 233-7 ...
  https://en.wikipedia.org/wiki/Interleukin-23_receptor
*  Interleukin 23 subunit alpha - Wikipedia
"Genetic variations in the interleukin-12/interleukin-23 receptor (beta1) chain, and implications for IL-12 and IL-23 receptor ... Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. IL-23 is produced by dendritic cells and ... Interleukin-23 is a heterodimeric cytokine composed of an IL-12p40 subunit that is shared with IL-12 and the IL-23p19 subunit. ... "Entrez Gene: IL23A interleukin 23, alpha subunit p19". Parham C, Chirica M, Timans J, Vaisberg E, Travis M, Cheung J, et al. ( ...
  https://en.wikipedia.org/wiki/Interleukin_23_subunit_alpha
*  IL23R - Interleukin-23 receptor precursor - Homo sapiens (Human) - IL23R gene & protein
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain ... R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling. R-HSA-9020933 Interleukin-23 signaling. ... Interleukin-23 receptorAdd BLAST. 606. Amino acid modifications. Feature key. Position(s). DescriptionActions. Graphical view. ... interleukin-23-mediated signaling pathway Source: Reactome. *negative regulation of interleukin-10 production Source: BHF-UCL , ...
  https://www.uniprot.org/uniprot/Q5VWK5
*  Interleukin-23 orchestrates mucosal responses to Salmonella enterica serotype Typhimurium in the intestine. - PubMed - NCBI
Interleukin-23 orchestrates mucosal responses to Salmonella enterica serotype Typhimurium in the intestine.. Godinez I1, ... Interleukin-23 Orchestrates Mucosal Responses to Salmonella enterica Serotype Typhimurium in the Intestine ... Interleukin-23 Orchestrates Mucosal Responses to Salmonella enterica Serotype Typhimurium in the Intestine ... Interleukin-23 Orchestrates Mucosal Responses to Salmonella enterica Serotype Typhimurium in the Intestine ...
  https://www.ncbi.nlm.nih.gov/pubmed/18955477
*  Interleukin 23 Receptor ELISA & Assay Kits
Compare and order Interleukin 23 Receptor ELISA Kits. View citations, images, detection ranges, sensitivity, prices and more. ... Interleukin 23 Receptor ELISA Kit. 18 products by 8 suppliers: Abbexa , Biomatik , Boster Bio , CUSABIO , Cloud-Clone , ... interleukin-23 receptor , interleukin 23 receptor , interleukin-23 receptor-like , IL-23 receptor , interleukin 23 receptor- ...
  https://www.antibodies-online.com/regulation-of-leukocyte-mediated-immunity-pathway-70/il23r-elisa-kit-11452/
*  Tristetraprolin regulation of interleukin 23 mRNA stability prevents a spontaneous inflammatory disease | JEM
Differential regulation of interleukin 12 and interleukin 23 production in human dendritic cells. J. Exp. Med. 205:1447-1461. ... Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature. 445:648-651. doi:10.1038/ ... How microorganisms tip the balance between interleukin-12 family members. Nat. Rev. Immunol. 8:81-86. doi:10.1038/nri2225. ... Tristetraprolin regulation of interleukin 23 mRNA stability prevents a spontaneous inflammatory disease. Céline Molle, Tong ...
  http://jem.rupress.org/content/210/9/1675
*  Overexpression of Interleukin-23 and Interleukin-17 in the Lesion of Pemphigus Vulgaris: A Preliminary Study
... Jixin Xue,1 ... Jixin Xue, Wenting Su, Zhiwei Chen, Youhui Ke, Xiaojing Du, and Qiaochu Zhou, "Overexpression of Interleukin-23 and Interleukin ...
  https://www.hindawi.com/journals/mi/2014/463928/cta/
*  Frontiers | Increased Interleukin-23 in Hashimoto's Thyroiditis Disease Induces Autophagy Suppression and Reactive Oxygen...
In this study, we found that thyroid follicular cells (TFCs) from HT patients expressed an elevated level of interleukin-23 (IL ... Additionally, IL-23-induced autophagy suppression and ROS accumulation in human TFCs was attributed to AKT/mTOR/NF-κB ... Additionally, IL-23-induced autophagy suppression and ROS accumulation in human TFCs was attributed to AKT/mTOR/NF-κB ... These results demonstrate a key role for IL-23 in HT pathogenesis and provide a potential therapeutic strategy against IL-23 or ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2018.00096/full
*  Functional analyses of the interaction of chicken interleukin 23 subunit p19 with IL-12 subunit p40 to form the IL-23 complex
... ... Moreover, IL-23α mRNA was more highly expressed than IL-12p40 and IL-12p35 mRNA in several organs of chickens infected with ... In addition, ChIL-23 complex are associated with IL-23R, IL-12Rβ1 receptors; activate the JAK2/TYK2, STAT1/3, SOCS1 genes, and ... Using bioinformatics tools, we identified the NF-κB, C/EBPα-β, c-Jun, c-Rel, AP-1, GATA-1, and ER promoter sites in ChIL-23α. ...
  https://insights.ovid.com/pubmed?PMID=29040919
*  Regulation of interleukin-12 and interleukin-23 production by tristetraprolin (TTP) | ScholarBank@NUS
LOW PEY YNG (2012-06-04). Regulation of interleukin-12 and interleukin-23 production by tristetraprolin (TTP). ScholarBank@NUS ... Despite the importance of the TH1/IL-12 and TH17/IL-23 axis in protective immunity, excessive production of IL-12 and IL-23 can ... IL-12 and IL-23 form a crucial link to adaptive immunity through their ability to influence the development of TH1 and TH17 ... This highlights the importance of regulating IL-12 and IL-23 production and we sought to investigate the ability of the mRNA- ...
  http://scholarbank.nus.edu.sg/handle/10635/35560
*  Interleukin-23 subunit alpha
This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 ... subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific ... IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor ... IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for ...
  https://pharos.nih.gov/idg/targets/IL23A
*  ActoFactor™ Recombinant Human Interleukin 23 | Creative Bioarray
IL-23 has been shown to enhance proliferation of memory T cells. It also stimulates the production of IFN-γ in NK cells, ... IL-23 is a proinflammatory heterodimeric protein composed of two subunits, a unique p19 subunit and a p40 subunit, which is ... IL-23 is secreted by activated dendritic cells and macrophages, and signals though a receptor comprised of IL-23R complexed ... Recombinant IL-23 is a 53.5 kDa heterodimeric protein consisting of two subunits, p19 (170 amino acids) and p40 (306 amino ...
  https://www.creative-bioarray.com/ActoFactor-Recombinant-Human-Interleukin-23-CSC-CTK0270-item-3596.htm
*  Gentaur Molecular :FabGennix \ Interleukin 23 P19, FITC conjugates \ IL23P19-110-FITC
Interleukin 23 P19, FITC conjugates \ IL23P19-110-FITC for more molecular products just contact us ... Il33] Interleukin-33 (IL-33) [Cleaved into: Interleukin-33(102-266); Interleukin-33(109-266)]. [Il18rap] Interleukin-18 ... Interleukin-1 HY1) (IL-1HY1) (Interleukin-1 delta) (IL-1 delta) (Interleukin-1 family member 5) (IL-1F5) (Interleukin-1 homolog ... Interleukin-1 HY1) (IL-1HY1) (Interleukin-1 delta) (IL-1 delta) (Interleukin-1 family member 5) (IL-1F5) (Interleukin-1 ...
  http://www.antibody-antibodies.com/product_det.php?id=3098743&supplier=search&name=Interleukin%2023%20P19,%20FITC%20conjugates%20
*  Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology. - Oxford Neuroscience
IL-23-driven inflammation has primarily been linked to the actions of T-helper type 17 (TH17) cells. Somewhat overlooked, IL-23 ... IL-23-responsive innate intestinal cells are also a feature of T-cell-dependent models of colitis. The transcription factor ROR ... The key role of interleukin (IL)-23 in the pathogenesis of autoimmune and chronic inflammatory disorders is supported by the ... Stimulation of colonic leukocytes with IL-23 induced the production of IL-17 and interferon-gamma exclusively by innate ...
  https://www.neuroscience.ox.ac.uk/publications/53303
*  The critical role of interleukin-23 in spondyloarthropathy. - The Kennedy Institute of Rheumatology
We will review the anatomical sites affected and the evidence for the importance of IL-23 in these conditions, before drawing ... Recently progress has been made because numerous independent studies have converged upon IL-23 as a central cytokine in ... Enthesitis, Interleukin-23, Spondyloarthropathy, T lymphocytes, Animals, Bone and Bones, Genetic Predisposition to Disease, HLA ... We will review the anatomical sites affected and the evidence for the importance of IL-23 in these conditions, before drawing ...
  https://www.kennedy.ox.ac.uk/publications/432682
*  The Role of Interleukin 23 In Colitis Associated Cancer - Sergei Grivennikov
The Role of Interleukin 23 In Colitis Associated Cancer Grivennikov, Sergei I. University of California San Diego, La Jolla, CA ... The Role of Interleukin 23 In Colitis Associated Cancer. Grivennikov, Sergei I. / University of California San Diego. $40,459. ... The Role of Interleukin 23 In Colitis Associated Cancer. Grivennikov, Sergei I. / University of California San Diego. $90,000. ... The Role of Interleukin 23 In Colitis Associated Cancer. Grivennikov, Sergei I. / Research Institute of Fox Chase Cancer Center ...
  http://grantome.com/grant/NIH/K99-DK088589-02
*  人IL-23 ELISA试剂盒(Interleukin-23) | Abcam中国官方网站
Interleukin-23) ELISA试剂盒datasheet (ab64708).Abcam抗体、ELISA、激动剂拮抗剂、表观遗传试剂、蛋白多肽 ... Combination use of immune complexes and a Ca2(+) channel blocker azelnidipine enhances interleukin-12 p40 secretion without T ... Interleukin-23) Human in vitro ELISA (Enzyme-Linked Immunosorbent Assay) kit is designed for the quantitative measurement of IL ... Interleukin-23). 参阅全部 IL23 试剂盒. ... Interleukin-23 subunit p19. *JKA3
  http://www.abcam.cn/human-il-23-elisa-kit-interleukin-23-ab64708.html
*  Interleukin-23 Receptor Gene Variants in Acute Lymphoblastic Leukemia and Their Relation to Prognostic Factors
Objective: To investigate the possible association of interleukin-23 receptor (IL23R) gene variants rs1884444, rs10889677 and ... Interleukin (IL)-23 has an important role in tumor immune regulation. ... Background: Interleukin (IL)-23 has an important role in tumor immune regulation. Objective: To investigate the possible ... "Interleukin-23 Receptor Gene Variants in Acute Lymphoblastic Leukemia and Their Relation to Prognostic Factors". Iranian ...
  http://iji.sums.ac.ir/article_39289.html
*  RIG‐I antiviral signaling drives interleukin23 production and psoriasis‐like skin disease | EMBO Molecular Medicine
Sivanesan D, Beauchamp C, Quinou C, Lee J, Lesage S, Chemtob S, Rioux JD, Michnick SW (2016) IL23R (interleukin 23 receptor) ... Zheng Y, Danilenko DM, Valdez P, Kasman I, Eastham‐Anderson J, Wu J, Ouyang W (2007) Interleukin‐22, a T(H)17 cytokine, ... RIG‐I antiviral signaling drives interleukin23 production and psoriasis‐like skin disease. Huiyuan Zhu, Fangzhou Lou, Qianqian ... Increased expression of interleukin 23 p19 and p40 in lesional skin of patients with psoriasis vulgaris. J Exp Med 199: 125-130 ...
  http://embomolmed.embopress.org/content/9/5/589
*  Interleukin (IL)-23 mediates Toxoplasma gondii-induced immunopathology in the gut via matrixmetalloproteinase-2 and IL-22 but...
Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat. Immunol. 10:857-863. ... Interleukin-22 but not interleukin-17 provides protection to hepatocytes during acute liver inflammation. Immunity. 27:647-659. ... Expression of interleukin-12-related cytokine transcripts in inflammatory bowel disease: elevated interleukin-23p19 and ... Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis. Nature. 445:648-651. doi:10.1038/ ...
  http://jem.rupress.org/content/206/13/3047