Interleukin 13 (IL-13) is a protein that in humans is encoded by the IL13 gene. IL-13 was first cloned in 1993 and is located ... Interleukin-13 has a critical role in goblet cell metaplasia. Goblet cells are filled with mucin (MUC). MUC5AC Mucin 5AC is a ... October 2004). "Interleukin-13 in the skin and interferon-gamma in the liver are key players in immune protection in human ... April 1993). "Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function". Proceedings of the ...
Interleukin-13 is a pleiotropic TH2 cytokine that has been shown to be central to the pathogenesis of asthma. Some of the most ... prominent of the effects of IL-13 include increases in goblet cell differentiation, activation of fibroblasts, elevation of ... Role of interleukin-13 in asthma Curr Allergy Asthma Rep. 2013 Oct;13(5):415-20. doi: 10.1007/s11882-013-0373-9. ... Interleukin-13 is a pleiotropic TH2 cytokine that has been shown to be central to the pathogenesis of asthma. Some of the most ...
Interleukin (IL)-13 is a key cytokine associated with the asthmatic phenotype. It signals via its cognate receptor, a complex ... Interleukin (IL)-13 is a key cytokine associated with the asthmatic phenotype. It signals via its cognate receptor, a complex ... Abbreviations: IL, interleukin; shIL-13R?1, soluble human IL-13 receptor ? chain 1; shIL-13R?2, soluble human IL-13 receptor ? ... Abbreviations: IL, interleukin; shIL-13R?1, soluble human IL-13 receptor ? chain 1; shIL-13R?2, soluble human IL-13 receptor ? ...
Interleukins 12 and 13 levels among beta-thalassaemia major patients ... Increased plasma levels of interleukin-6 and interleukin-8 in beta-thalassaemia major. Haematologia, 2001, 31:237-244. ... Increased plasma levels of interleukin-6 and interleukin-8 in beta-thalassaemia major. Haematologia, 2001, 31:237-244. ... Plasma interleukin-3 (IL-3) and IL-7 concentrations in children with homozygous beta-thalassemia. Journal of Tropical ...
Effects of Interleukin-13 Blockade on Allergen-induced Airway Responses in Mild Atopic Asthma Journal Articles ... CONCLUSIONS: IL-13 has a role in allergen-induced airway responses in humans. Further study is required to determine whether ... RATIONALE: Extensive evidence in animal models supports a role for IL-13 in the pathobiology of asthma. IMA-638 and IMA-026 are ... OBJECTIVES: We hypothesized that anti-IL-13 treatment would inhibit allergen-induced late-phase asthmatic responses, airway ...
he Evaluation of interleukin-4 and interleukin-13 in the Serum of Pulmonary Sarcoidosis and Tuberculosis Patients. by Ronald ... he Evaluation of interleukin-4 and interleukin-13 in the Serum of Pulmonary Sarcoidosis and Tuberculosis Patients ... he Evaluation of interleukin-4 and interleukin-13 in the Serum of Pulmonary Sarcoidosis and Tuberculosis Patients ... Interleukin-13 ameliorates postischemic hepatic gluconeogenesis and hyperglycemia in rat model of stroke. by Ronald ...
he Evaluation of interleukin-4 and interleukin-13 in the Serum of Pulmonary Sarcoidosis and Tuberculosis Patients. by Ronald ... he Evaluation of interleukin-4 and interleukin-13 in the Serum of Pulmonary Sarcoidosis and Tuberculosis Patients ... he Evaluation of interleukin-4 and interleukin-13 in the Serum of Pulmonary Sarcoidosis and Tuberculosis Patients ... Interleukin-13 ameliorates postischemic hepatic gluconeogenesis and hyperglycemia in rat model of stroke. by Ronald ...
Interleukin-13 receptor. In 2002 and 2003, Kawakami et al demonstrated that although several head and neck cancer cell lines ... Targets already used for head and neck cancer in animal models include epidermal growth factor receptors (EGFRs), interleukin- ... Basic fibroblast growth factor (bFGF), platelet-derived endothelial cell growth factor (PD-ECGF), and interleukin-8 (IL-8) are ... Improved anti-tumor activity and safety of interleukin-13 receptor targeted cytotoxin by systemic continuous administration in ...
Interleukin-22. Interleukin-22 is a member of the IL-10 family of cytokines and binds to IL-22R which is complex of IL-22R1 and ... Interleukin-23. Interleukin-23 is composed of the IL-12p40 and IL-23p19 subunits and is produced primarily by DCs and monocytes ... Interleukin-4 and interleukin-10 gene polymorphisms in patients with inflammatory bowel disease. Immunol Invest (2017) 46(7): ... Differential roles for interleukin-23 and interleukin-17 in intestinal immunoregulation. Immunity (2015) 43(4):739-50. doi: ...
Polyclonal Antibody to Interleukin 13 (IL13). PAA060Po01 * $37800 $378.00 Unit price/ per ...
Mouse IL13(Interleukin 13) ELISA Kit. Mouse IL13(Interleukin 13) ELISA Kit. To Order Contact us: [email protected] ... Description: A sandwich ELISA kit for detection of Interleukin 13 from Mouse in samples from blood, serum, plasma, cell culture ... Description: A sandwich quantitative ELISA assay kit for detection of Mouse Interleukin 13 (IL13) in samples from serum, plasma ... Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Interleukin 13 (IL13) in ...
Predictors of interleukin-33 and thymic stromal lymphopoietin levels in cord blood (abstract) ... Predictors of interleukin-33 and thymic stromal lymphopoietin levels in cord blood (abstract). ... The epithelial cell-derived cytokines, thymic stromal lymphopoietin (TSLP), and interleukin-33 (IL-33) have received attention ...
Description: A sandwich ELISA kit for detection of Interleukin 12B from Guinea pig in samples from blood, serum, plasma, cell ... Description: A sandwich ELISA kit for detection of Interleukin 18 from Guinea pig in samples from blood, serum, plasma, cell ... Description: A sandwich ELISA kit for detection of Interleukin 10 from Guinea pig in samples from blood, serum, plasma, cell ... Description: A sandwich ELISA kit for detection of Interleukin 18 from Pig in samples from blood, serum, plasma, cell culture ...
JO2-01 Effect of cellulose acetate beads on the release of interleukin-13 at different temperatures. poster at ISFA 2019 pag ... adsorptive apheresis (GMA), on the release of interleukin (IL)-13, an inflammatory cytokine. We. incubated peripheral blood ... The IL-13 concentration in the samples incubated without CA beads. increased as the temperature increased; however, the IL-13 ...
Interleukin-13 (IL-13) is a cytokine involved in Th2 immune response, which plays a role in susceptibility to infection by ... Divergent patterns of linkage disequilibrium and haplotype structure across global populations at the interleukin-13 (IL13) ... Since the mutation pair W748S+E1143G has also been described in European patients, we examined the haplotypes of 13 non-Finnish ...
Interleukin-13 / pharmacology * Interleukin-2 / pharmacology * Interleukin-4 / pharmacology * Lipopolysaccharides / ...
Modulation of mucus production by interleukin-13 receptor α2 in the human airway epithelium (Clinical and Experimental Allergy) ... Modulation of mucus production by interleukin-13 receptor α2 in the human airway epithelium (Clinical and Experimental Allergy) ... Modulation of mucus production by interleukin-13 receptor α2 in the human airway epithelium (Clinical and Experimental Allergy) ... Modulation of mucus production by interleukin-13 receptor α2 in the human airway epithelium (Clinical and Experimental Allergy ...
IL-13 enhanced stem cell factor (SCF)-induced proliferation of Lin-Sca-1+ bone marrow progenitor cells more potently than IL-4 ... In contrast, IL-13 had no synergistic activity on SCF-induced proliferation of the more mature Lin-Sca-1- progenitor cells. ... Thus, the cloning frequency in response to SCF + IL-13 was at least 20-fold higher in the Lin-Sca-1+ than the Lin-Sca-1- ... Furthermore, IL-13 but not IL-4 synergistically enhanced colony formation of Lin-Sca-1+ progenitors in response to granulocyte/ ...
involved_in interleukin-13-mediated signaling pathway ISS Inferred from Sequence or Structural Similarity. more info ... enables interleukin-4 receptor binding ISS Inferred from Sequence or Structural Similarity. more info ... involved_in positive regulation of interleukin-4-mediated signaling pathway ISS Inferred from Sequence or Structural Similarity ...
Animals, Cell Line, CHO Cells, Cricetinae, Humans, Interleukin-10, Interleukin-12, Interleukin-13, Interleukin-4, Kinetics, ... Interleukin (IL)-10, IL-4, IL-13, and transforming growth factor (TGF)-beta are usually considered to be the most important ... Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood ... Stimulatory and inhibitory effects of interleukin (IL)-4 and IL-13 on the production of cytokines by human peripheral blood ...
In macrophages and lung cells, AKR1B10 overexpression induces the expression of the proinflammatory cytokines interleukin-6 (IL ... When stimulated by IL-4 or IL-13, macrophages undergo alternative (M2) activation [27]. In general, M2 cells acquired in ... THP-1 cells were treated with 100 ng/ml phorbol 12-myristate 13-acetate (PMA, AdipoGen, San Diego, CA, U.S.A.) for 24 h. Once ... 13]. M1 macrophages are the first line of defense against microbial infection. M1 macrophages maintain a strong antigen- ...
Patients received Unituxin in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-2 (IL-2 ... GM-CSF, granulocyte-macrophage colony-stimulating factor; IL-2, interleukin-2; RA, 13-cis-retinoic acid. ... Unituxin (dinutuximab) is indicated, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin ... and interleukin-2 (IL-2) plus RA, followed by 1 cycle of RA alone. Patients randomized to the RA arm received up to 6 cycles of ...
Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor β1. J. Exp. Med. ... Interleukin-17A antagonist attenuates radiation-induced lung injuries in mice. Exp. Lung Res. 40, 77-85 (2014). ... Neutralization of interleukin-17 attenuates cholestatic liver fibrosis in mice. Scand. J. Immunol. 83, 102-108 (2016). ... Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis. Sci. Transl. Med. 11, eaaw1237 (2019). ...
View Human IL-13 Alexa Fluor® 350-conjugated Antibody (FAB213U-100UG) datasheet. ... Interleukin 13. Entrez Gene IDs. 3596 (Human); 16163 (Mouse); 116553 (Rat); 574325 (Primate) ... IL-13 binds with low affinity to IL-13 R alpha 1, triggering IL-13 R alpha 1 association with IL-4 R alpha. This high affinity ... Reviews for Human IL-13 Alexa Fluor® 350-conjugated Antibody. There are currently no reviews for this product. Be the first to ...
Y. M. Zhu, S. J. Webster, D. Flower, and P. J. Woll, "Interleukin-8/CXCL8 is a growth factor for human lung cancer cells," ... interleukin-12 (IL-12), reactive nitrogen (iNOS), and oxygen intermediates (ROS). In addition, M1 macrophages promote T-helper- ... interleukin 12 (IL-12), reactive nitrogen, and oxygen intermediates. M1-activated macrophages are part of the polarized Th1 ... S. Fichtner-Feigl, M. Terabe, A. Kitani et al., "Restoration of tumor immunosurveillance via targeting of interleukin-13 ...
Glutamine Blocks Interleukin-13-Induced Intestinal Epithelial Barrier Dysfunction Gastroenterologia (September,2019) ... 13.. Fu HX, Yang ST, Wang MQ, Wang JF, Tang IC: Butyric acid production from lignocellulosic biomass hydrolysates by engineered ... C.t was obtained from Ohio State University and cultured anaerobically at 37°C in clostridial growth medium (CGM) [13]. C.t was ...
Interleukin-5 (Interleukin 5)IBA 05/01/2009 - "There was a significant reduction in lung eosinophilia and IL-5 in high-fat fed ... Interleukin-12 (IL 12)IBA 09/01/2000 - "Mucosal IL-12 is more effective than systemic IL-12 in augmenting IFN-gamma expression ... Interleukin-13IBA 07/01/2013 - "In conclusion, our data establish that allergen-induced EoE pathogenesis is independent of IL- ... 02/01/2009 - "In the present study, the dependence of PGD(2)-induced eosinophil accumulation in vivo on interleukin-5 (IL-5) ...
Pulmonary fibrosis share the pathogenesis process of interstitial lung disease which involve the pulmonary parenchyma. Although the exact pathogenesis is not fully understood, there are many initiating factors which cause the pulmonary tissue injury. The primary features of the lung injury includes inflammation, fibrosis, and granulomas development. ...
Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a ... The interleukin 33/suppression of tumorigenicity 2 (IL33/ST2) axis has been implicated in multiple human diseases including ... Genetic association studies of interleukin-13 receptor alpha1 subunit gene polymorphisms in asthma and atopy. European ... IL-33 is more potent than IL-25 in provoking IL-13-producing nuocytes (type 2 innate lymphoid cells) and airway contraction ...