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*  Patent US6451983 - Tumor necrosis factor antibodies - Google Patents
... characterization and comparison with the actions of interleukin 1," Proc. Natl. Acad. Sci. USA Medical Sciences 83:4533-4537. ... 10(1):117-127.. 21. Watanabe, N. et al., (1986) "Analysis of the TNF receptors of kym cells by affinity cross-linking" Japanese ... MAbs 1, 47 and 54, which have been shown in competition binding studies to share an epitope on TNF, can be seen to have highly ... 11 and 18). The results for day 1, 2.5 ug and 1 ug TNF and day 2, 5 ug, 2.5 ug and lug are statistically significant in a t- ...
  http://www.google.co.uk/patents/US6451983
*  Interleukin-1 receptor antagonist gene polymorphism in human colorectal cancer
... Viet, Hung Trinh Vietnam National University, ... interleukin-1 receptor antagonist; polymorphism; VNTR; colorectal cancer National Category Medical and Health Sciences ... There is evidence that pro-inflammatory cytokines such as interleukin-1 (IL-1) are critically involved with tumour progression ... IL-1 receptor antagonist (IL-1Ra) is known to down regulate and limit the inflammatory response. Therefore we attempted to ...
  http://liu.diva-portal.org/smash/record.jsf?pid=diva2:661605
*  Immobilization increases interleukin-6, but not tumour necrosis factor-a, release from the leg during exercise in humans -...
Immobilization increases interleukin-6, but not tumour necrosis factor-a, release from the leg during exercise in humans. * ... Data on interleukin-6 (IL-6) and tumour necrosis factor-a (TNF-a) release during acute exercise are not conclusive, and ... Exercise; Exercise Test; Femoral Vein; Humans; Immobilization; Interleukin-6; Leg; Male; Oxygen Consumption; Regional Blood ... Interleukin-6 release occurred after 15 min of exercise, and the release from the IM leg was significantly greater compared ...
  http://www.forskningsdatabasen.dk/catalog/236579463
*  TNF Blockade Unable to Halt OA Joint Erosion | Medpage Today
... are thought to result from actions of cytokines such as TNF and interleukin-1 on osteoclasts and effects on bone remodeling. ... In patients treated with adalimumab, 2.1% of the pre-erosive joints had progressed to erosion after 1 year, compared with 3.6% ...
  https://www.medpagetoday.com/rheumatology/arthritis/32744
*  Interleukin-1 conserved site (IPR020877) | InterPro | EMBL-EBI
Interleukin-1 conserved site (IPR020877). Short name: IL-1_CS Description. Interleukin-1 alpha and interleukin-1 beta (IL-1 ... Crystallographic refinement of interleukin 1 beta at 2.0 A resolution.. Proc. Natl. Acad. Sci. U.S.A. 86 9667-71 1989 ... Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors.. J. ... The highest degree of similarity is to the human and murine interleukin-1 receptors, although both proteins are related to a ...
  http://www.ebi.ac.uk/interpro/entry/IPR020877
*  Interleukin-1 receptor type 1 (IPR004076) | InterPro | EMBL-EBI
Crystallographic refinement of interleukin 1 beta at 2.0 A resolution.. Proc. Natl. Acad. Sci. U.S.A. 86 9667-71 1989 ... Interleukin-1 alpha and interleukin-1 beta (IL-1 alpha and IL-1 beta) are cytokines that participate in the regulation of ... Interleukin-1 receptor family (IPR015621) *Interleukin-1 receptor type I/II (IPR004074) *Interleukin-1 receptor type 1 ( ... This entry represents Interleukin-1 receptor type 1 (IL1R1), the crystal structure of the soluble extracellular part of type-I ...
  http://www.ebi.ac.uk/interpro/entry/IPR004076
*  'interleukin 1' Protocols and Video...
... interleukin 1' include 'Microinjection of CRISPR/Cas9 Protein into Channel Catfish, Ictalurus punctatus, Embryos for Gene ... Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay', 'Screening Assay ... Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells', 'Systematic ... Interleukin-1alpha and Interleukin-1beta. The biological effects of Il-1 include the ability to replace macrophage requirements ...
  https://www.jove.com/keyword/interleukin+1
*  Human interleukin 1. Purification to homogeneity. | JEM
Human interleukin 1. Purification to homogeneity.. S R Kronheim, C J March, S K Erb, P J Conlon, D Y Mochizuki, T P Hopp ... We have purified human interleukin 1 (IL-1) to homogeneity by a simplified procedure that results in excellent yields of pure ... IL-1, secreted by human peripheral blood macrophages that have been stimulated with Staphylococcus aureus, was purified by ion ... No molecular weight heterogeneity was observed, in contrast to findings for mouse IL-1 and earlier reports of human IL-1. ...
  http://jem.rupress.org/content/161/3/490
*  Interleukin-1 receptor - Wikipedia
Interleukin-1 receptor (IL-1R) is a cytokine receptor which binds interleukin 1. Two forms of the receptor exist. The type I ... Arend WP (1991). "Interleukin 1 receptor antagonist. A new member of the interleukin 1 family". J. Clin. Invest. 88 (5): 1445- ... Wesche H, Korherr C, Kracht M, Falk W, Resch K, Martin MU (March 1997). "The interleukin-1 receptor accessory protein (IL-1RAcP ... Receptors, Interleukin-1 at the US National Library of Medicine Medical Subject Headings (MeSH). ...
  https://en.wikipedia.org/wiki/Interleukin-1_receptor
*  interleukin-1 (IL-1)
... By Ivan Suarez Robles 08 Feb, 2011 A cytokine that is involved with various inflammatory activities. ...
  https://web.stanford.edu/group/hopes/cgi-bin/hopes_test/glossary/interleukin-1-il-1/
*  Interleukin-1 family - Wikipedia
Liu N, Li X, Liu C, Zhao Y, Cui B, Ning G (2010). "The association of interleukin-1alpha and interleukin-1beta polymorphisms ... The Interleukin-1 family (IL-1 family) is a group of 11 cytokines, which plays a central role in the regulation of immune and ... The interleukin-1 superfamily has 11 members, which have similar gene structure, although originally it contained only four ... Dinarello CA (2011). "Interleukin-1 in the pathogenesis and treatment of inflammatory diseases". Blood. 117 (14): 3720-32. doi: ...
  https://en.wikipedia.org/wiki/Interleukin-1_family
*  Interleukin 1 beta - Wikipedia
... interleukin-6 and interleukin-8 in the pathogenesis of the otitis media with effusion". Eur. Cytokine Netw. 13 (2): 161-72. ... There are two genes for interleukin-1 (IL-1): IL-1 alpha and IL-1 beta (this gene). IL-1β precursor is cleaved by cytosolic ... "Entrez Gene: IL1B interleukin 1, beta". Masters SL, Simon A, Aksentijevich I, Kastner DL (2009). "Horror autoinflammaticus: the ... This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. The molecular weight of the ...
  https://en.wikipedia.org/wiki/Interleukin_1_beta
*  Interleukin-1 beta - Proteopedia, life in 3D
3] Mizutani H, Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human ... Human Interleukin-1 Beta THREE-DIMENSIONAL STRUCTURE OF IL-1β The molecule contains 12 antiparallel β-strands. The molecule has ... 5] Guy P. A. Vigers, Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1β, Nature 1997,386,190- ... 4] B Veerapandian, Structure and function of interleukin-1, based on crystallographic and modeling studies,Biophys J.1992, ...
  http://proteopedia.org/wiki/index.php/Interleukin-1_beta
*  Topological frustration and the folding of interleukin-1 beta. - PubMed - NCBI
The cytokine, interleukin-1beta (IL-1beta), adopts a beta-trefoil fold. It is known to be much slower folding than similarly ... Topological frustration and the folding of interleukin-1 beta.. Gosavi S1, Chavez LL, Jennings PA, Onuchic JN. ... 1. Center for Theoretical Biological Physics, University of California San Diego, 9500 Gilman Drive, La Jolla, CA 92037, USA.. ...
  https://www.ncbi.nlm.nih.gov/pubmed/16469330
*  INTERLEUKIN 1 | The Journal of Rheumatology
The Journal of Rheumatology January 1 2017, 44 (1) 102-109; DOI: https://doi.org/10.3899/jrheum.160518 ...
  http://www.jrheum.org/keyword/interleukin-1
*  Receptors interleukin-1 - Biology-Online Dictionary
receptors, interleukin-1 specific molecular sites or structures on cells with which interleukin-1 reacts or to which it binds ... The il-1 receptor on t-lymphocytes and fibroblasts is composed of a single polypeptide chain that binds both il-1 alpha and il- ... Retrieved from "https://www.biology-online.org/dictionary/index.php?title=Receptors_interleukin-1&oldid=65867" ... 1 beta. The molecular weight of this high-affinity receptor is believed to be 80 kD. ...
  https://www.biology-online.org/dictionary/Receptors_interleukin-1
*  Downregulation of Renin Gene Expression by Interleukin-1 | Hypertension
Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever. J Infect Dis. 1990;161:79 ... Downregulation of Renin Gene Expression by Interleukin-1. Nenad Petrovic, Colleen M. Kane, Curt D. Sigmund, Kenneth W. Gross ... Interleukin-1 and interleukin-1 antagonism in sepsis, systemic inflamatory response syndrome, and septic shock. Shock. 1995;3: ... Downregulation of Renin Gene Expression by Interleukin-1. Nenad Petrovic, Colleen M. Kane, Curt D. Sigmund and Kenneth W. Gross ...
  http://hyper.ahajournals.org/content/30/2/230
*  Anti-Interleukin-1 in Diabetes Action - Full Text View - ClinicalTrials.gov
Anti-Interleukin-1 in Diabetes Action (AIDA). The safety and scientific validity of this study is the responsibility of the ... The anti-interleukin-1 in type 1 diabetes action trial--background and rationale. Diabetes Metab Res Rev. 2009 May;25(4):321-4 ... Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled ... The aim of the Anti-Interleukin-1 in Diabetes Action trial (AIDA) study is to test the feasibility, safety/tolerability and ...
  https://clinicaltrials.gov/show/NCT00711503
*  Interleukin-1 receptor family - Wikipedia
The term interleukin-1 includes IL-1α, IL-1β and Interleukin 1 receptor antagonist (IL-1Ra). IL-1Rs are involved in immune host ... Jul 1993). "Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4". Science. 261: 472-5. doi: ... There are four main groups of TIR domain-containing proteins in animals; Toll-like receptors, Interleukin-1 receptor (IL-1R), ... Weber A, Wasiliew P, Kracht M (Jan 2010). "Interleukin-1 (IL-1) pathway". Journal Nature Reviews Immunology. Dinarello CA. (Apr ...
  https://en.wikipedia.org/wiki/Interleukin-1_receptor_family
*  The Multiple Biological Properties of Interleukin-1 Influencing Immunocompetent Cells | SpringerLink
... generalized reaction despite the fact that most disease processes which induce circulating IL-1 produced at the site of the ... Cloning and expression of murine interleukin-1 in Escherchia coli. Nature 312:458, (1984).ADSCrossRefGoogle Scholar ... Interleukin-1 activity in the synovial fluid of patients with rheumatoid arthritis. Rheumatol. Internat. 2:49, (1982).CrossRef ... Human large granular lymphocytes are potent producers of interleukin-1. Nature 309:56, (1984).ADSCrossRefGoogle Scholar ...
  https://link.springer.com/chapter/10.1007/978-1-4684-5323-2_10
*  Interleukin 1 receptor antagonist - Wikipedia
The interleukin-1 receptor antagonist (IL-1RA) is a protein that in humans is encoded by the IL1RN gene. IL-1RA was initially ... Interleukin 1 receptor antagonist is used in horses for the treatment of equine lameness secondary to joint and soft-tissue ... An interleukin 1 receptor antagonist is used in the treatment of rheumatoid arthritis, an autoimmune disease in which IL-1 ... "Entrez Gene: IL1RN interleukin 1 receptor antagonist". Langdahl BL, Løkke E, Carstens M, Stenkjaer LL, Eriksen EF (March 2000 ...
  https://en.wikipedia.org/wiki/Interleukin_1_receptor_antagonist
*  Interleukin 1 in ulcerative colitis. | Gut
Role of interleukin 1 in inflammatory bowel disease--enhanced production during active disease. ...
  http://gut.bmj.com/content/32/3/338.2
*  410) A1(interleukin-1) = receptor antagonist
... (411) Anti(interleukin-1) = f (412) Adv0(use) = clinically. (413) Bon(interleukin-1) = proinflammatory. (414) Contr1(interleukin-1) = interleukin-2. (415) Contr2(interleukin-1) = interleukin-3. (416) Contr3(interleukin-1) = interleukin-4. (417) Contr4(interleukin-1) = interleukin-5. (418) Contr5(interleukin-1) = interleukin-6. (419) Fact1 (interleukin-1) = use. (420) Func1(interleukin-1) = Inhibit (induction of apoptosis). (421) Gener(interleukin-1) = Proinflammatory cytokine. (422) Nocer (Interleukin-1) = deprive of. (423) Oper1 (interleukin-1) = use (man). (424) Oper2 (gene) = encode (gene). (426) Syn (Interleukin-1) = f (427) Sloc(interleukin-1) = DNA. (428) S1(interleukin-1) = enzyme. (429) S2(interleukin-1) = neoplasm. (430) ...
  http://elies.rediris.es/elies6/interleukinLF.htm
*  Salivary Interleukin-1 Beta - Salimetrics
Interleukin-1β (IL-1 beta) is one of a family of biologically active small protein molecules known as cytokines. Cytokines are ... APPROVED SALIVARY IL-1 BETA COLLECTION METHODS. SalivaBio Passive Drool Adults, Children 6+ ... 1,2,3) IL-1β is an example of a pro-inflammatory cytokine, since it is involved in the body's inflammatory response to acute or ... 4,5) IL-1β is therefore frequently used as a bio-marker of inflammation. (6,7) A study with normal mouse parotid acinar cells ...
  https://www.salimetrics.com/analyte/salivary-interleukin-1-beta/
*  WikiGenes - IL1R2 - interleukin 1 receptor, type II
Synonyms: CD121 antigen-like family member B, CD121b, CDw121b, IL-1 type II receptor, IL-1R-2, ... ...
  https://www.wikigenes.org/e/gene/e/7850.html