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*  Morphogen gradients: from generation to interpretation. - PubMed - NCBI
Signal Transduction/physiology*. Substance. *Intercellular Signaling Peptides and Proteins. Grant support. *R01 GM056211/GM/ ... In its simplest incarnation, a morphogen signal forms a gradient by diffusion from a local source and clearance in surrounding ... The graded activity of morphogens within tissues exposes cells to different signal levels and leads to region-specific ... Morphogens are long-range signaling molecules that pattern developing tissues in a concentration-dependent manner. ...
  https://www.ncbi.nlm.nih.gov/pubmed/21801015?dopt=Abstract
*  Ephrin A4 - Wikipedia
Intercellular signaling peptides and proteins / ligands. Growth factors. *Epidermal growth factor. *Fibroblast growth factor ... cell-cell signaling. • ephrin receptor signaling pathway. • axon guidance. • osteoclast differentiation. • bone remodeling. ... Three transcript variants that encode distinct proteins have been identified.[6] References[edit]. *^ a b c GRCh38: Ensembl ... Binding proteins: IGFBP (1, 2, 3, 4, 5, 6, 7). *Cleavage products/derivatives with unknown target: Glypromate (GPE, (1-3)IGF-1) ...
  https://en.wikipedia.org/wiki/EFNA4
*  Ephrin A5 - Wikipedia
Intercellular signaling peptides and proteins / ligands. Growth factors. *Epidermal growth factor. *Fibroblast growth factor ... Reverse signaling in growth cone survival[edit]. "Reverse" signaling is one unique property of ephrin ligands that allows for ... Binding proteins: IGFBP (1, 2, 3, 4, 5, 6, 7). *Cleavage products/derivatives with unknown target: Glypromate (GPE, (1-3)IGF-1) ... protein binding. Cellular component. • membrane. • plasma membrane. • anchored component of external side of plasma membrane. • ...
  https://en.wikipedia.org/wiki/EFNA5
*  Transforming growth factor beta superfamily - Wikipedia
Intercellular signaling peptides and proteins / ligands. Growth factors. *Epidermal growth factor. *Fibroblast growth factor ... Receptor/signaling modulators. Signaling peptide/protein receptor modulators. Growth factor receptor modulators. Cytokine ... TGF-beta-1 is a peptide of 112 amino acid residues derived by proteolytic cleavage from the C-terminal of a precursor protein. ... These proteins interact with a conserved family of cell surface serine/threonine-specific protein kinase receptors, and ...
  https://en.wikipedia.org/wiki/Tgf_beta_superfamily
*  Parathyroid hormone-related protein - Wikipedia
Intercellular signaling peptides and proteins / ligands. Growth factors. *Epidermal growth factor. *Fibroblast growth factor ... G-protein coupled receptor signaling pathway. • bone mineralization. • negative regulation of chondrocyte development. ... Parathyroid hormone-related protein (or PTHrP) is a protein member of the parathyroid hormone family. It is occasionally ... adenylate cyclase-activating G-protein coupled receptor signaling pathway. • cAMP metabolic process. • positive regulation of ...
  https://en.wikipedia.org/wiki/Parathyroid_hormone-related_protein
*  NOTCH2 gene | Cancer Genetics Web
Intercellular Signaling Peptides and Proteins. *Splenic Neoplasms. *fms-Like Tyrosine Kinase 3 ... The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between ... positive regulation of Ras protein signal transduction - protein binding - pulmonary valve morphogenesis - receptor activity - ... This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions ...
  http://www.cancerindex.org/geneweb/NOTCH2.htm
*  HES1 | Cancer Genetics Web
Amyloid Precursor Protein Secretases. *Intercellular Signaling Peptides and Proteins. *Membrane Proteins. *Down-Regulation ... positive regulation of tyrosine phosphorylation of Stat3 protein - protein binding - protein complex assembly - protein ... smoothened signaling pathway - somatic stem cell maintenance - STAT protein import into nucleus - telencephalon development - ... Recombination signal-binding protein Jκ (RBPJ) is a key transcription factor downstream of receptor activation in Notch ...
  http://www.cancerindex.org/geneweb/HES1.htm
*  Independent circadian and sleep/wake regulation of adipokines and glucose in humans.
Intercellular Signaling Peptides and Proteins / blood*. Leptin / blood*. Male. Middle Aged. Obesity / etiology. Sleep / ... 0/Adiponectin; 0/Blood Glucose; 0/Insulin; 0/Intercellular Signaling Peptides and Proteins; 0/Leptin ...
  http://www.biomedsearch.com/nih/Independent-circadian-regulation-adipokines-glucose/15687326.html
*  Associations among plasma adiponectin, hypertension, left ventricular diastolic function and left ventricular mass index.
0/Adiponectin; 0/Intercellular Signaling Peptides and Proteins From MEDLINE®/PubMed®, a database of the U.S. National Library ... Intercellular Signaling Peptides and Proteins / blood*. Male. Middle Aged. Ventricular Function, Left. ...
  http://www.biomedsearch.com/nih/Associations-among-plasma-adiponectin-hypertension/15581338.html
*  A factor(s) secreted from MIN-6 beta-cells stimulates differentiation of definitive endoderm enriched embryonic stem cells...
... and signalling molecules secreted from, surrounding cells. These factors are best studied using explant cultures of embryonic ... Intercellular Signaling Peptides and Proteins / pharmacology*, secretion. Mice. Pancreas / cytology, drug effects, embryology, ... 0/Culture Media, Conditioned; 0/Intercellular Signaling Peptides and Proteins From MEDLINE®/PubMed®, a database of the U.S. ... suggesting that it was a protein or peptide. Further analyses showed that insulin or proinsulin failed to mimic the effects of ...
  http://www.biomedsearch.com/nih/factors-secreted-from-MIN-6/20674663.html
*  LH-induced neuregulin 1 (NRG1) type III transcripts control granulosa cell differentiation and oocyte maturation.
0/Intercellular Signaling Peptides and Proteins; 0/Ligands; 0/Neuregulin-1; 0/Nrg1 protein, mouse; 0/RNA, Messenger; 117147-70- ... Intercellular Signaling Peptides and Proteins / pharmacology. Ligands. Luteinizing Hormone / pharmacology*. Mice. Molecular ... Proto-Oncogene Proteins c-akt / metabolism. RNA, Messenger / genetics, metabolism. Receptor Protein-Tyrosine Kinases / ... EC 2.7.11.1/Proto-Oncogene Proteins c-akt; EC 2.7.11.24/Extracellular Signal-Regulated MAP Kinases ...
  http://www.biomedsearch.com/nih/LH-Induced-Neuregulin-1-NRG1/21047912.html
*  Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis,...
0/Grn protein, mouse; 0/Intercellular Signaling Peptides and Proteins From MEDLINE®/PubMed®, a database of the U.S. National ... Intercellular Signaling Peptides and Proteins / genetics, metabolism*. Mice. Mice, Inbred BALB C. Placenta / metabolism. ... Next Document: Candidate testis-determining gene, Maestro (Mro), encodes a novel HEAT repeat protein.. ...
  http://www.biomedsearch.com/nih/Progranulin-cell-derived-growth-epithelin/12889069.html
*  Pathophysiology and treatment of septic shock in neonates.
0/Acute-Phase Proteins; 0/Anti-Infective Agents; 0/Intercellular Signaling Peptides and Proteins; 0/Opsonin Proteins; 9007-36-7 ... Intercellular Signaling Peptides and Proteins / immunology. Multiple Organ Failure / immunology, microbiology, physiopathology ... Opsonin Proteins / immunology. Proteomics / methods. Resuscitation / methods*. Risk Factors. Shock, Septic / immunology, ... Complement System Proteins / immunology. Endothelium, Vascular / immunology. Genomics / methods. Humans. Hydrocortisone / ...
  http://www.biomedsearch.com/nih/Pathophysiology-treatment-septic-shock-in/20569817.html
*  Carl Hashimoto, PhD | Yale School of Medicine
Intercellular Signaling Peptides and Proteins; Proteolysis Research Organizations. Cell Biology: Developmental Cell Biology and ... Specialized Terms: Proteolysis; Serpins; Intercellular signaling; Morphogenesis; Disease modeling; Drosophila molecular ... Spatial regulation of developmental signaling by a serpin. Hashimoto, C., Kim, D.R., Weiss, L.A., Miller, J.W. and Morisato, D ... Hashimoto C, Kim DR, Weiss LA, Miller JW, Morisato D: Spatial regulation of developmental signaling by a serpin. Dev Cell. 2003 ...
  http://medicine.yale.edu/intranet/facultybydept/carl_hashimoto-2.profile
*  TNF-Related Apoptosis-Inducing Ligand | Harvard Catalyst Profiles | Harvard Catalyst
Intercellular Signaling Peptides and Proteins [D12.644.276]. *Cytokines [D12.644.276.374]. *Tumor Necrosis Factors [D12.644. ... A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that ... The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form. ... Derakhshan A, Chen Z, Van Waes C. Therapeutic Small Molecules Target Inhibitor of Apoptosis Proteins in Cancers with ...
  https://connects.catalyst.harvard.edu/Profiles/display/Concept/TNF-Related%20Apoptosis-Inducing%20Ligand
*  Epoetin Alfa - Epogen Summary Report | CureHunter
... protein and 38% carbohydrate), regulates red blood cell production. Epoetin alfa is produced by Chinese hamster ovary cells ... Peptides: 22950*Intercellular Signaling Peptides and Proteins: 12097*Cytokines: 54678*Hematopoietic Cell Growth Factors: 11* ... Intercellular Signaling Peptides and Proteins: 12097*Cytokines: 54678*Hematopoietic Cell Growth Factors: 11*Colony-Stimulating ... Intercellular Signaling Peptides and Proteins: 12097*Cytokines: 54678*Hematopoietic Cell Growth Factors: 11*Colony-Stimulating ...
  http://www.curehunter.com/public/keywordSummaryD019322.do
*  Lubricants Summary Report | CureHunter
Intercellular Signaling Peptides and Proteins (Growth Factors) 3. Cytokines 4. Proteins (Proteins, Gene) ... and matrix proteins; and secretion of lubricants to protect the tissue from abrasion, adhesion, infection, and tumor ...
  http://www.curehunter.com/public/keywordSummaryD054327-Lubricants.do
*  Transforming Growth Factor beta3 - TGF beta 3 Summary Report | CureHunter
The association of the cleavage products results in the formation a latent protein which must be activated to bind its receptor ... It is synthesized as a precursor molecule that is cleaved to form mature TGF-beta3 and TGF-beta3 latency-associated peptide. ... Amino Acids, Peptides, and Proteins*Proteins: 90489*Intercellular Signaling Peptides and Proteins: 12097*Cytokines: 54678* ... Peptides: 22950*Intercellular Signaling Peptides and Proteins: 12097*Cytokines: 54678*Transforming Growth Factor beta: 11179* ...
  http://www.curehunter.com/public/keywordSummaryD053782.do
*  Wnt5a regulate VEGF-A165b expression via Ror2/JNK/SC35- | Open-i
VEGF-A165b protein expression was measured by western immunoblot ana ... Intercellular Signaling Peptides and Proteins/genetics. *Mice. *Mice, Knockout. *Mice, Transgenic. *Protein Isoforms ... VEGF-A165b protein expression was measured by western immunoblot analysis in the presence or absence of recombinant Wnt5a in ... e. SC35 protein expression was measured by western blot analysis in the presence or absence of stimulation with recombinant ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC4257756_emss-60202-f0004&req=4
*  Compensatory Refeeding and Neuropeptide mRNA levels in | Open-i
High Mobility Group Proteins/genetics/metabolism. *Intercellular Signaling Peptides and Proteins/genetics/metabolism ... Mentions: Because Pomc neurons serve as primary hypothalamic sensors for adiposity signals, we suspected that hyperphagia and ... Mentions: Because Pomc neurons serve as primary hypothalamic sensors for adiposity signals, we suspected that hyperphagia and ... through their opposing effects on melanocortin receptor signaling. In previous studies, Pomc mutant mice became obese, but Agrp ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC1287504_pbio.0030415.g008&req=4
*  Janus kinase - wikidoc
Animal intercellular signaling peptides and proteins. Growth factors. Epidermal growth factor - Fibroblast growth factor (FGF2 ... they rely on the JAK family of tyrosine kinases to phosphorylate and activate downstream proteins involved in their signal ... signalling, whereas JAK1 and TYK2 are involved type I interferon signalling. Mice that do not express TYK2 have defective ... Abelson leukemia virus protein - c-Kit - C-MET - Flt3 - Janus kinase (Janus kinase 1, Janus kinase 2, Janus kinase 3, Tyrosine ...
  http://wikidoc.org/index.php/JAK2
*  Interleukin-10 - MeSH - NCBI
All MeSH CategoriesChemicals and Drugs CategoryAmino Acids, Peptides, and ProteinsPeptidesIntercellular Signaling Peptides and ... All MeSH CategoriesChemicals and Drugs CategoryAmino Acids, Peptides, and ProteinsProteinsIntercellular Signaling Peptides and ... All MeSH CategoriesChemicals and Drugs CategoryBiological FactorsIntercellular Signaling Peptides and ProteinsCytokines ... Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein. ...
  https://www.ncbi.nlm.nih.gov/mesh?Db=mesh&Cmd=DetailsSearch&Term=%22Interleukin-10%22%5BMeSH+Terms%5D
*  Regulation of T cell development by Mib1 in the thymic | Open-i
Intercellular Signaling Peptides and Proteins/metabolism. *Mice. *Mice, Transgenic. *RNA Interference. *Receptors, Notch/ ... Notch signaling regulates lineage decisions at multiple stages of lymphocyte development, and Notch activation requires the ... Notch signaling regulates lineage decisions at multiple stages of lymphocyte development, and Notch activation requires the ... Interestingly, when BM cells from transgenic Notch reporter mice were transplanted into Mib1- mice, the Notch signaling was ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2571928_jem2052525f05&req=4
*  all pediatric l1 2005:2010[pubdate] *count=100 - BioMedLib™ search engine
Chemical-registry-number] 0 / Cytokines; 0 / Intercellular Signaling Peptides and Proteins; 0 / Iron Chelating Agents; 0 / ... Fas Ligand Protein / metabolism. Fas Ligand Protein / pharmacology. Mice. Mice, Inbred C57BL. Mice, Knockout. Signal ... Chemical-registry-number] 0 / Antigens, CD95; 0 / Fas Ligand Protein; 0 / Fas protein, mouse; 0 / Fasl protein, mouse; 0 / ... Chemical-registry-number] 0 / Antigens, CD95; 0 / Dietary Fats; 0 / Fabp4 protein, mouse; 0 / Fatty Acid-Binding Proteins ...
  http://www.bmlsearch.com/?kwr=all+pediatric+l1+2005:2010%5Bpubdate%5D&cxts=100&stmp=b0
*  Yeast two-hybrid screening for angiostatin-binding prot | Open-i
Yeast two-hybrid screening for angiostatin-binding proteins in a human placenta cDNA library. (A) Yeast transfected with the ... Intercellular Signaling Peptides and Proteins*. *Neovascularization, Physiologic/physiology*. *Peptide Fragments/metabolism*. * ... This fusion protein was expressed in yeast and did not activate the His or β-gal reporter genes when expressed alone or in ... This fusion protein was expressed in yeast and did not activate the His or β-gal reporter genes when expressed alone or in ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2199208_JCB0010121.f1&req=4