Integrin beta-4 signaling plays a key role in mouse embryogenesis. - PCRM Vancouver Fertility Clinic
Custom Human Integrin beta-4/CD104 IQELISA™ Kit | RayBiotech
Integrin beta-4 (CD104 Microplate (Item A)**: 96 well PCR plate coated with anti-Human Integrin beta-4 (CD104 ... Detection Affinity Reagent for Integrin beta-4 (CD104 (Item F): 2 vials of a 4x concentrated solution of anti-Human Integrin ... Custom Human Integrin beta-4/CD104 IQELISA™ Kit Be the first to review this product ... Standards and samples are pipetted into the wells and Integrin beta-4 (CD104 present in a sample is bound to the wells by the ...
Integrin beta 4 - Wikipedia
"Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and ... Biffo S, Sanvito F, Costa S, Preve L, Pignatelli R, Spinardi L, Marchisio PC (Nov 1997). "Isolation of a novel beta4 integrin- ... Biffo S, Sanvito F, Costa S, Preve L, Pignatelli R, Spinardi L, Marchisio PC (Nov 1997). "Isolation of a novel beta4 integrin- ... Hogervorst F, Kuikman I, von dem Borne AE, Sonnenberg A (Mar 1990). "Cloning and sequence analysis of beta-4 cDNA: an integrin ...
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and...
Home » beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal ... beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and ... beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and ... Expression of beta4 integrin that lacks the hemidesmosome targeting domain interferes with tissue polarity and NFkappaB ...
Fras1 MGI Mouse Gene Detail - MGI:2385368 - Fraser extracellular matrix complex subunit 1
Live tumor imaging shows macrophage induction and TMEM-mediated enrichment of cancer stem cells during metastatic dissemination...
Epidermolysis Bullosa: Practice Essentials, Pathophysiology, Etiology
... and alpha-6-beta-4 integrin. The beta-4 integrin subunit performs a central role in hemidesmosome formation and contains an ... Mutations of the genes coding for beta-4 and alpha-6 integrin also have been associated with junctional epidermolysis bullosa. ... These structures contain the extracellular portions of collagen XVII (BP180) and alpha-6-beta-4 integrin. In addition, ... a6 integrin, and b4 integrin have been demonstrated. [6] ... collagenous protein that interacts with alpha-4 integrin and ...
Epidermolysis bullosa with pyloric atresia: MedlinePlus Genetics
Pulkkinen L, Kim DU, Uitto J. Epidermolysis bullosa with pyloric atresia: novel mutations in the beta4 integrin gene (ITGB4). ... Like α6β4 integrin, plectin helps attach the epidermis to underlying layers of skin. Some PLEC gene mutations prevent the cell ... The proteins produced from the ITGA6 and ITGB4 genes join to form a protein known as α6β4 integrin. This protein plays an ... A shortage of functional α6β4 integrin causes cells in the epidermis to be fragile and easily damaged. Friction or other minor ...
SMART: FN3 domain annotation
Crystal structure of a complex between integrin beta4 and plectin. 3f7q. First pair of Fibronectin type III domains and part of ... Integrin beta-4 (P16144) (SMART). OMIM:147557: Epidermolysis bullosa, junctional, with pyloric atresia. OMIM:226730: ... Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin. 4mmy. Integrin AlphaVBeta3 ectodomain bound to the ... CRYSTAL STRUCTURE OF A TANDEM PAIR OF FIBRONECTIN TYPE III DOMAINS FROM THE CYTOPLASMIC TAIL OF INTEGRIN ALPHA6 BETA4. ...
SMART: FN3 domain annotation
Crystal structure of a complex between integrin beta4 and plectin. 3f7q. First pair of Fibronectin type III domains and part of ... Integrin beta-4 (P16144) (SMART). OMIM:147557: Epidermolysis bullosa, junctional, with pyloric atresia. OMIM:226730: ... Integrin AlphaVBeta3 ectodomain bound to the tenth domain of Fibronectin. 4mmy. Integrin AlphaVBeta3 ectodomain bound to the ... CRYSTAL STRUCTURE OF A TANDEM PAIR OF FIBRONECTIN TYPE III DOMAINS FROM THE CYTOPLASMIC TAIL OF INTEGRIN ALPHA6 BETA4. ...
A role for PVRL4-driven cell-cell interactions in tumorigenesis | eLife
2005) Beta4 integrin subunit gene expression correlates with tumor size and nuclear grade in early breast cancer Mod Pathol 18: ... 2007) Targeting integrin beta4 for cancer and anti-angiogenic therapy Trends Pharmacol Sci 28:506-511. ... 2007) Intrinsic signaling functions of the beta4 integrin intracellular domain J Biol Chem 282:30322-30330. ... 2006) Loss of beta4 integrin subunit reduces the tumorigenicity of MCF7 mammary cells and causes apoptosis upon hormone ...
Tumor Progression Is Mediated by Thymosin-β4 through a TGFβ/MRTF Signaling Axis | Molecular Cancer Research | American...
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair ... SCAI acts as a suppressor of cancer cell invasion through the transcriptional control of beta1-integrin ... TRIM27/MRTF-B-dependent integrin β1 expression defines leading cells in cancer cell collectives ...
Epidermolysis Bullosa: Practice Essentials, Pathophysiology, Etiology
... and alpha-6-beta-4 integrin. The beta-4 integrin subunit performs a central role in hemidesmosome formation and contains an ... Mutations of the genes coding for beta-4 and alpha-6 integrin also have been associated with junctional epidermolysis bullosa. ... These structures contain the extracellular portions of collagen XVII (BP180) and alpha-6-beta-4 integrin. In addition, ... a6 integrin, and b4 integrin have been demonstrated. [6] ... collagenous protein that interacts with alpha-4 integrin and ...
Suprabasal Dsg2 expression in transgenic mouse skin confers a hyperproliferative and apoptosis-resistant phenotype to...
Beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and ... Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of ...
Effects of thymosin β4 on wound healing of rat palatal mucosa
Bock-Marquette I, Saxena A, White MD, Dimaio JM and Srivastava D: Thymosin beta4 activates integrin-linked kinase and promotes ... Reti R, Kwon E, Qiu P, Wheater M and Sosne G: Thymosin beta4 is cytoprotective in human gingival fibroblasts. Eur J Oral Sci. ... Philp D, Scheremeta B, Sibliss K, Zhou M, Fine EL, Nguyen M, Wahl L, Hoffman MP and Kleinman HK: Thymosin beta4 promotes matrix ... Huff T, Otto AM, Müller CS, Meier M and Hannappel E: Thymosin beta4 is released from human blood platelets and attached by ...
Aberrant Activation Of Hedgehog Signalling Promotes Cell Migration And Invasion Via Matrix Metalloproteinase-7 In Ovarian...
... of Gli transcription factor leads to the inhibition of migration and invasion of ovarian cancer cells via integrin beta4- ... Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target. Cancer Res. 2008;68: ... Several classes of proteins, including calcium-dependent cadherins, integrins, extracellular proteases, angiogenetic factors ... Sawada revealed that ovarian cancer metastasis is most likely induced by upregulation of the alpha 5-integrin mediated by E- ...
Integrin β7 Rabbit Polyclonal Antibody - Cotinis the genus of scarab beetles
Description: A polyclonal antibody for detection of Integrin Beta4 from Human, Mouse, Rat. This Integrin Beta4 antibody is for ... Description: A polyclonal antibody for detection of Integrin Beta4 from Human, Mouse, Rat. This Integrin Beta4 antibody is for ... Description: A polyclonal antibody for detection of Integrin Beta4 from Human, Mouse, Rat. This Integrin Beta4 antibody is for ... Integrin β7 Rabbit Polyclonal Antibody. To Order: [email protected]. Integrin α4 Polyclonal Antibody. ...
Integrin αX Rabbit Polyclonal Antibody - Western Blot Antibodies - Bioworld Consulting Laboratories, LLC.
Description: A polyclonal antibody for detection of Integrin Beta4 from Human, Mouse, Rat. This Integrin Beta4 antibody is for ... Description: A polyclonal antibody for detection of Integrin Beta4 from Human, Mouse, Rat. This Integrin Beta4 antibody is for ... Description: A polyclonal antibody for detection of Integrin Beta4 from Human, Mouse, Rat. This Integrin Beta4 antibody is for ... Description: A polyclonal antibody for detection of Integrin Beta4 from Human, Mouse, Rat. This Integrin Beta4 antibody is for ...
Human ITGb4(Integrin Beta 4) ELISA Kit - Hudsen
Description: ITGB4 (Integrin, beta-4), also known as CD104 (Cluster of Differentiation 104), is a human gene. The gene encodes ... The integrin beta-4 subunit is characterized by an unusually long cytoplasmic domain that harbors 4 fibronectin type III (FNIII ... The integrin beta-4 subunit is characterized by an unusually long cytoplasmic domain that harbors 4 fibronectin type III (FNIII ... Description: Recombinant Rat Integrin beta-4(Itgb4),partial expressed in in vitro E.coli expression system ...
The epithelial-mesenchymal transition: new insights in signaling, development, and disease | Journal of Cell Biology |...
beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and ... beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and ... Other TGF-β targets include integrins β4 and α6. Richard Bates (University of Massachusetts, Worcester, MA) reported that the ... Colorectal cancer progression: integrin alphavbeta6 and the epithelial-mesenchymal transition (EMT). Cell Cycle. ...
alpha(6) Integrin is the main receptor of human papillomavirus type 16 VLP
... integrins were determined and compared with the amount of HPV-VLP binding in ten cell lines … ... Integrin alpha6 * Integrin beta1 / metabolism * Integrin beta4 * Oncogene Proteins, Viral / metabolism * Papillomaviridae / ... alpha(6) Integrin is the main receptor of human papillomavirus type 16 VLP Biochem Biophys Res Commun. 2001 May 11;283(3):668- ... Both the expression level of alpha(6) integrin and the amount of HPV-VLP binding were high in cervical cancer cell lines, as ...
Beta lactams. Medical search
HeterocyclicIntegrin alpha5beta1Peptides, CyclicIntegrin beta4Integrin alpha6beta4Integrin beta Chainsbeta 2-Glycoprotein IAza ... HeterocyclicIntegrin alpha5beta1Peptides, CyclicIntegrin beta4Chromatography, PaperIntegrin alpha6beta4Integrin beta Chainsbeta ... Integrin beta4. Also known as CD104 antigen, this protein is distinguished from other beta integrins by its relatively long ... Integrin beta3. An integrin beta subunit of approximately 85-kDa in size which has been found in INTEGRIN ALPHAIIB-containing ...
Junctional Epidermolysis Bullosa - GeneReviews® - NCBI Bookshelf
Chavanas S, Gache Y, Vailly J, Kanitakis J, Pulkkinen L, Uitto J, Ortonne J, Meneguzzi G. Splicing modulation of integrin beta4 ... α6β4 integrin comprises one α6 and one β4 integrin protein from the integrin family of proteins and is a component of the ... Integrins associate in pairs containing one alpha and one beta chain. α6β4 integrin comprises one α6 and one β4 integrin from ... Micheloni A, De Luca N, Tadini G, Zambruno G, DAlessio M. Intracellular degradation of beta4 integrin in lethal junctional ...
Genome-wide association scan for QTL and their positional candidate genes associated with internal organ traits in chickens |...
Pulkkinen L, Kim DU, Uitto J. Epidermolysis bullosa with pyloric atresia: novel mutations in the beta4 integrin gene (ITGB4). ... The integrin subunit beta 4 (ITGB4) gene is located within the QTL on GGA18 (rs315188853 - rs312861933) explaining 2.98% of the ... genetic variance for GIZZP and encodes ß4 integrin polypeptides [53]. In humans, several studies reported both lethal and ... bullosa-pyloric atresia syndrome and altered basement membrane zone immunofluorescence for the alpha6beta4 integrin. J Invest ...
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Faculty Profiles - KARIYA Yoshinobu
Beta4 Integrin and EGF Coordinately Regulate Electric Field-mediated Directional Migration via Rac1. ... binds syndecan-1 and regulates cellular adhesion and migration by suppressing phosphorylation of integrin beta4 chain. ... Laminin-332 and Integrins: Signaling Platform for Cell Adhesion and Migration and its Regulation by N-Glycosylation. ... short arm of laminin-5 gamma2 chain regulates cellular adhesion and migration by preventing phosphorylation of integrin beta4 ...