*  Reactome | VCAM1 binds Integrin alpha4beta1
Integrin cell surface interactions (Bos taurus) * VCAM1 binds Integrin alpha4beta1 (Bos taurus) ...
  http://www.reactome.org/content/detail/R-BTA-198941
*  Reactome | Integrin alpha4beta1 binds JAM2:JAM3
Integrin cell surface interactions (Gallus gallus) * Integrin alpha4beta1 binds JAM2:JAM3 (Gallus gallus) ...
  http://www.reactome.org/content/detail/R-GGA-202706
*  Details and Download Full Text PDF: Alpha4beta1 integrin blockade after spinal cord injury decreases damage and improves...
Alpha4beta1 integrin blockade after spinal cord injury decreases damage and improves neurological function.. Authors:. ... The integrin alpha4beta1, expressed by these leukocytes, is a key to their activation and migration into/within tissue. ... The leukocyte integrin alpha4beta1 is crucial for their entry. The authors previously demonstrated that an anti-alpha4 ... Timing and duration of anti-alpha4beta1 integrin treatment after spinal cord injury: effect on therapeutic efficacy.. Authors: ...
  https://www.pubfacts.com/detail/19038604/Alpha4beta1-integrin-blockade-after-spinal-cord-injury-decreases-damage-and-improves-neurological-fu
*  Contribution of alpha4beta1 integrin to the antiallergic effect of levocabastine | IRIS Università degli Studi di Catania
... integrin by reducing infiltrated eosinophils. We propose that blockade of integrin-mediated cell adhesion might be a target of ... integrin by reducing infiltrated eosinophils. We propose that blockade of integrin-mediated cell adhesion might be a target of ... The adhesion molecule integrin alpha(4)beta(1) is expressed in eosinophils; it interacts with the vascular cell adhesion ... The adhesion molecule integrin alpha(4)beta(1) is expressed in eosinophils; it interacts with the vascular cell adhesion ...
  https://www.iris.unict.it/handle/20.500.11769/51349
*  NCAM1 Gene - GeneCards | NCAM1 Protein | NCAM1 Antibody
Integrin α4β1 inhibitor, Highly potent and selective inhibitor of integrin alpha4beta1. 0. ... Highly potent and selective inhibitor of integrin alpha4beta1. 327613-57-0. Echistatin, alpha1 isoform. alphaVbeta3 and ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=NCAM1
*  CD169 mediates the capture of exosomes in spleen and lymph node | Blood Journal
Exosomes released during reticulocyte maturation bind to fibronectin via integrin alpha4beta1. Eur J Biochem. 2000;267(2):583- ... DC-derived exosomes abundantly express the ligand milk-fat globule lactadherin, a potential ligand for the αvβ3/β5 integrins.38 ... Adhesion and signaling by B cell-derived exosomes: the role of integrins. FASEB J. 2004;18(9):977-979. ...
  http://www.bloodjournal.org/content/123/2/208?sso-checked=true
*  Effect of rhSCF on the adhesion of human eosinophils t | Open-i
3). Treatment with rhSCF did not change the surface expression of integrin α4, α6, β1, α4β7, or c-kit receptor as evaluated by ... 3). Treatment with rhSCF did not change the surface expression of integrin α4, α6, β1, α4β7, or c-kit receptor as evaluated by ... Cell adhesion to FN40 was completely inhibited with antibodies against the alpha4 and beta1 integrin subunits, revealing that ... Cell adhesion to FN40 was completely inhibited with antibodies against the alpha4 and beta1 integrin subunits, revealing that ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC2198988_JEM.970564f3&req=4
*  LPS-Induced TLR4 Signaling in Human Colorectal Cancer Cells Increases β1 Integrin-Mediated Cell Adhesion and Liver Metastasis |...
Integrin alpha4beta1/VCAM-1 pathway mediates primary adhesion of RAW117 lymphoma cells to hepatic sinusoidal endothelial cells ... For β1 integrin blockade, β1 integrin functional blocking antibody (2.0 μg/mL) or isotype control IgG1 (2.0 μg/mL) were ... Increased extracellular pressure enhances cancer cell integrin-binding affinity through phosphorylation of beta1-integrin at ... Akt1 signaling regulates integrin activation, matrix recognition, and fibronectin assembly. J Biol Chem 2007;282:22964-76. ...
  http://cancerres.aacrjournals.org/content/71/5/1989
*  Erythroid cells generated in the absence of specific β1-integrin heterodimers accumulate reactive oxygen species at homeostasis...
Alpha4beta1 integrin and erythropoietin mediate temporally distinct steps in erythropoiesis: integrins in red cell development ... Proteomic analysis of alpha4beta1 integrin adhesion complexes reveals alpha-subunit-dependent protein recruitment. Proteomics. ... Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation ... Integrin-dependent signaling in erythroid cells. How are the phenotypic differences between α4- and α 5-integrins molecularly ...
  http://www.haematologica.org/content/98/11/1769
*  IGSF8 - Wikipedia
2004). "EWI-2 modulates lymphocyte integrin alpha4beta1 functions". Blood. 103 (8): 3013-9. doi:10.1182/blood-2003-07-2201. ... Stipp CS, Kolesnikova TV, Hemler ME (2004). "EWI-2 regulates alpha3beta1 integrin-dependent cell functions on laminin-5". J. ... 2006). "Contrasting effects of EWI proteins, integrins, and protein palmitoylation on cell surface CD9 organization". J. Biol. ...
  https://en.wikipedia.org/wiki/IGSF8
*  The effect of anti-integrin monoclonal antibodies on antigen-induced pulmonary inflammation in allergic rabbits. - Semantic...
... integrin), CD18 (beta(2) integrin) and the alpha sub-units of beta(2) integrin CD11a (LFA-1 integrin) and CD11b (Mac-1 integrin ... Treatment with the other anti-integrin mAbs had no effect on the acute bronchoconstriction after inhaled Ag challenge.Pre- ... treatment with the anti-integrin mAbs had differential effects in blocking the recruitment of inflammatory cells 24 h after ... The integrin adhesion molecules are involved in the recruitment and activation of inflammatory cells at sites of inflammation ...
  https://www.semanticscholar.org/paper/The-effect-of-anti-integrin-monoclonal-antibodies-Gascoigne-Holland/835de195266434990ac0574291b231f6938e9321
*  Table of Contents | Journal of Cell Science
Osteopontin is a ligand for the alpha4beta1 integrin K.J. Bayless, G.A. Meininger, J.M. Scholtz, G.E. Davis ... Vitronectin regulates smooth muscle contractility via alphav and beta1 integrin L.M. Dahm, C.W. Bowers ...
  http://jcs.biologists.org/content/111/9.most-read
*  BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways | JCB
Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation ... Integrin-linked kinase associated with integrin activation. Blood. 113:5304-5313. doi:10.1182/blood-2008-07-169136. ... which then activates integrin-linked kinase 1 (ILK-1) via α4-integrins. ILK-1 then induces the Wnt-PCP pathway by binding a ... We show that FN interacts with α4-integrins to activate integrin-linked kinase 1 (ILK-1). This leads to the formation of a ...
  http://jcb.rupress.org/content/192/1/171.full
*  PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP | Journal of Cell Science
Reinhardt, P. H., Elliott, J. F. and Kubes, P. (1997). Neutrophils can adhere via alpha4beta1-integrin under flow conditions. ... Gao, X., Xu, N., Sekosan, M., Mehta, D., Ma, S. Y., Rahman, A. and Malik, A. B. (2001). Differential role of CD18 integrins in ... Heit, B., Colarusso, P. and Kubes, P. (2005). Fundamentally different roles for LFA-1, Mac-1 and {alpha}4-integrin in ... A second potential mechanism resulting in this delay is an alteration in the activation patterns of integrins (Reinhardt et al ...
  http://jcs.biologists.org/content/121/2/205
*  TR 14035 - AdisInsight
TR 14035 is an orally active dual α4β7/α4β1 integrin antagonist. It was originated by Tanabe Seiyaku and was being developed by ... Mechanism of Action Alpha4-beta7 integrin antagonists; Integrin alpha4beta1 antagonists * Orphan Drug Status Orphan designation ...
  http://adisinsight.springer.com/drugs/800012563?error=cookies_not_supported&code=940db574-f584-4dd3-8819-cf1d29e0a660
*  CiNii 論文 - Raised Serum Chondroitin Sulfate Epitope Level in Ovarian Epithelial Cancer ...
A role of chondroitin sulfate glycosaminoglycan binding site in alpha4beta1 integrin-mediated melanoma cell adhesion IIDA J. ...
  http://ci.nii.ac.jp/naid/10018841588
*  Experience of in vitro fertilization surrogacy in Finland.
Next Document: Expression of alpha(v)beta3 and alpha4beta1 integrins throughout the putative window of implantation.... ...
  http://www.biomedsearch.com/nih/Experience-in-vitro-fertilization-surrogacy/12174160.html
*  Leucine-Aspartic Acid-Valine Sequence as Targeting Ligand and Drug Carrier for Doxorubicin Delivery to Melanoma Cells: In Vitro...
... as targeting ligand and drug carrier for targeted delivery to integrin α4β1 over-expressing cancer cells. ... Garcia-Gila M, Cabanas C, Garcia-Pardo A. Analysis of the activation state of alpha4beta1 integrin in human B cell lines ... alpha4beta1 integrin)-mediated cell adhesion based on the Ile-Leu-Asp-Val tetrapeptide. J Pept Sci. 2000;6:321-41.CrossRef ... alpha4beta1 integrin)-mediated cell adhesion. Discovery of compounds like cyclo(MePhe-Leu-Asp-Val-D-Arg-D-Arg) (ZD7349) ...
  https://rd.springer.com/article/10.1007/s11095-009-9971-6
*  Gut-specific homing - Wikipedia
"Intracellular signaling required for CCL25-stimulated T cell adhesion mediated by the integrin alpha4beta1". J. Leukoc. Biol. ... Additionally, this integrin was much more common on CD8+ T cells activated in the Peyer's patches (PP T-cells) compared to ... These integrins interact with E-selectin molecules found on inflamed skin. Breast specific homing- Involved in the redirection ... This process relies on the key interaction between the integrin α4β7 and the addressin MadCAM-1 on the surfaces of the ...
  https://en.wikipedia.org/wiki/Gut-specific_homing
*  Protocols and Video Articles Authored by Mark D. Bass
... we have examined differences in the mechanism of focal adhesion formation mediated by the FN-binding integrins alpha4beta1 and ... SHARPINing Integrin Inhibition Nature Cell Biology. Nov, 2011 , Pubmed ID: 22048411 The activity state of integrins is crucial ... Proteomic Analysis of Integrin Adhesion Complexes Science Signaling. 2011 , Pubmed ID: 21467297 Integrin receptors regulate ... SHARPIN is now shown to negatively regulate integrin activation by binding the α-integrin subunit and interfering with the ...
  https://www.jove.com/author/Mark+D._Bass
*  ADAM28 - Wikipedia
2003). "Integrin alpha4beta1-dependent adhesion to ADAM 28 (MDC-L) requires an extended surface of the disintegrin domain". ... 2002). "The lymphocyte metalloprotease MDC-L (ADAM 28) is a ligand for the integrin alpha4beta1". J. Biol. Chem. 277 (5): 3784- ...
  https://en.wikipedia.org/wiki/ADAM28
*  Protocols and Video Articles Authored by Lawrence Steinman
Recent work has revealed the role of three key molecules in relapse and remission: alpha4beta1 integrin (also known as VLA4) is ... in the case of osteopontin and alpha4beta1 integrin) and then to terminate them as remissions in multiple sclerosis (in the ... osteopontin binds to alpha4beta1 integrin, stimulating the production of pro-inflammatory cytokines and inhibiting apoptosis; ... In this Charcot Lecture, I shall focus on osteopontin-the binding partner for alpha4 beta 1 integrin, on alpha B crystallin and ...
  https://www.jove.com/author/Lawrence_Steinman
*  Protocols and Video Articles Authored by Ming H. Lye (Translated to Russian)
1 supports specific eosinophil adhesion via alpha4beta1 integrin. We tested the hypothesis that adhesive contacts formed by ... In contrast, nontransformed fibroblasts on VCAM-1 formed peripheral focal adhesions that were positive for alpha4, beta1, ... The structures contained beta1 integrin subunit, phosphotyrosine-containing proteins, punctate filamentous actin, and gelsolin ...
  https://www.jove.com/author/Ming+H._Lye?language=Russian
*  Junctional adhesion molecule C (JAM-C) dimerization aids cancer cell migration and metastasis, Biochimica et Biophysica Acta ...
Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin ... JAM2 interacts with alpha4beta1. Facilitation by JAM3. Cunningham, S.A.; Rodriguez, J.M.; Arrate, M.P.; Tran, T.M.; Brock, T.A. ... Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion ... The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin mac-1 ...
  https://www.deepdyve.com/lp/elsevier/junctional-adhesion-molecule-c-jam-c-dimerization-aids-cancer-cell-9qR05bRWWA