Collagen, type XXIII, alpha 1 - Wikipedia
... novel ligand for integrin alpha2beta1 in the epidermis". J. Biol. Chem. 286 (31): 27804-13. doi:10.1074/jbc.M111.220046. PMC ... Integrin α2β1 is a collagen-binding integrin present at the epidermis, therefore this is the location where the interaction ... Cellular receptors for collagens belong to the family of β1 integrins. Collagen XXIII interacts in an ion-and conformation- ... Collagen Protein domain Transmembrane protein Non-small-cell lung carcinoma Prostate cancer Homotrimer Lipid raft Integrin, ...
Staff Listing in the Biomolecular Science and Medicinal Chemistry Division - The University of Nottingham
Structure of the integrin alpha2beta1-binding collagen peptide. Journal of Molecular Biology. 335(4), 1019-28 ... Structural determinants of integrin binding to the talin rod. The Journal of biological chemistry. 284(13), 8866-76 ... Integrin connections to the cytoskeleton through talin and vinculin. Biochemical Society transactions. 36(Pt 2), 235-9 ... Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib. Blood advances. 3(9 ...
Basic aspects of tumor cell fatty acid-regulated signaling and transcription factors | SpringerLink
SMART: VWA domain annotation
I DOMAIN FROM INTEGRIN ALPHA2-BETA1. 1atz. HUMAN VON WILLEBRAND FACTOR A3 DOMAIN. ... INTEGRIN ALPHA M I DOMAIN. 1mhp. Crystal structure of a chimeric alpha1 integrin I-domain in complex with the Fab fragment of a ... Integrin I domain of complement receptor 3 in complex with C3d. 4mmx. Integrin AlphaVBeta3 ectodomain bound to the tenth domain ... Re-refinement of Integrin AlphaIIbBeta3 Headpiece Bound to Antagonist L-739758. 2vdk. Re-refinement of Integrin AlphaIIbBeta3 ...
Thieme E-Journals - Thrombosis and Haemostasis / Abstract
Kelly Marshall McNagny - UBC Professor - Faculty Member - Researcher - Supervisor
The v-erbA oncogene blocks expression of alpha2/beta1 integrin a normal inhibitor of erythroid progenitor proliferation. (2002) ... Integrin alpha 2 beta 1 mediates interactions between developing embryonic retinal cells and collagen (1995). Development, 121 ... and disrupted integrin targeting to the basolateral surface. To determine whether podocalyxin has a definitive role in breast ...
![Reactome | 3x4Hyp-GalHyl-COL2A1(182-1241) [extracellular region]](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAYAAAAf8/9hAAACDklEQVQ4jW2ST0sbURTFf3dmMon/qYiWVtyF7hKXXYW4tHTrFygEiq78BNIPUSkEpPu6KqUuSkmaRTduTLoqpWDC2Ooolkw0GTOZuV1Ep4mdAw8e571z7r3nPUhA3fWou16x7nqVpPNRWGPCMw+EoqI7AkUQAMr11jLwtJRf2b9vYIxWRLSCUhGkCEI3CCnXW6+Bn8AGQOmgkSkdNBZjgyO3XQAqwyVFBLpByNFZm0/H5wCbgB1Gmil9bGwCP0ALALm9L0jd9fTOrReEfL+8pul1iW7Zh1Npml6XluczaZkAqOrG4Wn7AtiJDc67fb6eXMbCMFKaXo+rYIA/iJiwDB6kU3T6A47bPccPo2UgikPsh1Esdjo9vp138AcRj2cyqCrXQcjZ9Q2dfgiwDKDgGElPc9Lx8QcRADeDkIten99XsRjAAbYEslaSAYBtGszaJhe9IOZShvBoOsN8JrX99vnqPtz7B0OhsDBpM/wDcb7M2BZP5qcwZJwfHcFZmEixMGGTNg1EwDRkrPpQjA/ijhpUgbWTK387bZmICKYIc7bF0mQ6NlDFR9kFsuX1XC02UNW1/OJs9bYrB2UL+DBtW/yrD39ugvflZ7mt8nrOGR3ZWF2aG+6EGpAtra7sRooP9IE3CfmOIQ6xlF9xR/h3wPbhafsX8BLVYXcJkCTyDvm9mgF8Bl4pVBsvCv/d+Qt+deSvq9D1CQAAAABJRU5ErkJggg==)
Reactome | 3x4Hyp-GalHyl-COL2A1(182-1241) [extracellular region]
Integrin alpha2beta1,alpha3:beta1:(collagen,laminin,fibronectin) [plasma membrane] (Gallus gallus) * Collagen, laminin, ... Non-integrin membrane-ECM interactions (Gallus gallus) * DDR2 binds collagen type I, II, III, V, X fibrils (Gallus gallus) * ...
Reactome | Laminin-213 [extracellular region]
![Integrin alpha 2/CD49b Antibody (HAS3) [Unconjugated] (MAB1233): Novus Biologicals](data:image/png;base64,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)
Integrin alpha 2/CD49b Antibody (HAS3) [Unconjugated] (MAB1233): Novus Biologicals
View Mouse Monoclonal anti-Integrin alpha 2/CD49b Antibody (HAS3) [Unconjugated] (MAB1233). Validated Applications: Flow, IP, ... Londrigan S, Graham K, Takada Y, Halasz P, Coulson B Monkey rotavirus binding to alpha2beta1 integrin requires the alpha2 I ... Integrin alpha 2 is one of twelve integrin family alpha subunits that share the beta 1 subunit (1‑3). Integrin alpha 2 beta 1 ... Home » Integrin alpha 2/CD49b » Integrin alpha 2/CD49b Antibodies » Integrin alpha 2/CD49b Antibody (HAS3) [Unconjugated] ...
MeSH Browser
Integrins (1994-2002). Public MeSH Note. 2003; INTEGRIN ALPHA2BETA1 was indexed under INTEGRINS 1994-2002. History Note. 2003; ... Integrin alpha2beta1 Preferred Concept UI. M0417889. Registry Number. 0. Scope Note. An integrin found on fibroblasts, ... Integrins [D12.776.543.750.705.408] * Receptors, Fibronectin [D12.776.543.750.705.408.530] * Integrin alpha2beta1 [D12.776. ... Integrin alpha2beta1 Preferred Term Term UI T141800. LexicalTag NON. ThesaurusID NLM (2003). ...
Dynamics of transcriptome changes during subcutaneous preadipocyte differentiation in ducks | BMC Genomics | Full Text
... muscle insulin resistance is associated with extracellular matrix remodeling and interaction with integrin alpha2beta1 in mice ... term integrins subunit beta 1 (ITGB1) and CD44 were positively correlated with insulin resistance and glycemic control in human ...
Recognition and catabolism of synthetic heterotrimeric collagen peptides by matrix metalloproteinases
Structure of the integrin alpha2beta1-binding collagen peptide.. Emsley J, Knight CG, Farndale RW, Barnes MJ., J Mol Biol 335(4 ...
Reactome | 3x4Hyp-GlcGalHyl-COL6A1 [extracellular region]
Collagen types III, IV, V, VI, VIII, IX, XVI bind integrins alpha1beta1 and alpha2beta1 (Homo sapiens) * Collagen types III, IV ... Collagen types III, IV, V, VI, VIII, IX, XVI:Integrins alpha1beta 1, alpha2beta1 [plasma membrane] (Homo sapiens) * Collagen ... Collagen types VI, IX bind integrin alpha10beta1 (Homo sapiens) * Collagen tupe VI network, Collagen type IX:Integrin ...
Coagulants. Medical search
Integrin alpha2beta1 is thought to be essential for platelet adhesion to subendothelial collagens, facilitating subsequent ... Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen. (7/178). Platelet adhesion on ... including alpha2beta1 integrin, which strengthens adhesion without being essential. (+info). Femoral artery thrombosis after ... On the other hand, we show that platelets lacking GPVI can not activate integrins and consequently fail to adhere to and ...
Platelet adhesion and adhesive proteins--how to measure the platelet adhesiveness - Fingerprint - Keio University
Integrin alpha2beta1 7% * Afibrinogenemia 7% * Collagen Receptors 6% * Platelet Count 4% * Fibrinogen 4% ...
Page 1 | Search Results | Blood | American Society of Hematology
CD49b - wikidoc
1aox: I DOMAIN FROM INTEGRIN ALPHA2-BETA1. 1aox: I DOMAIN FROM INTEGRIN ALPHA2-BETA1 ... The CD49b protein is an integrin alpha subunit. It makes up half of the α2β1 integrin duplex. Integrins are heterodimeric ... Porter JC, Hogg N (1999). "Integrins take partners: cross-talk between integrins and other membrane receptors". Trends Cell ... Integrin alpha-2 or CD49b (cluster of differentiation 49b) is a protein which in humans is encoded by the CD49b gene. ...
Bio2Vec
In vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cells<...
Integrin alpha2beta1 Medicine & Life Sciences 100% * Rhabdomyosarcoma Medicine & Life Sciences 70% * adhesion receptor Medicine ... Cloned integrin α2 subunit complementary DNA was expressed on human rhabdomyosarcoma (RD) cells to give a functional VLA-2 (α2β ... N2 - Cloned integrin α2 subunit complementary DNA was expressed on human rhabdomyosarcoma (RD) cells to give a functional VLA-2 ... AB - Cloned integrin α2 subunit complementary DNA was expressed on human rhabdomyosarcoma (RD) cells to give a functional VLA-2 ...
Cybase
Alkalies. Medical search
Human keratinocytes and fibroblasts adhered to the alkali-treated collagen via the collagen receptor integrin alpha2beta1. This ... collagen retained the triple helical conformation and the ligand activity for the cell adhesion via alpha2beta1 integrin. (2/ ...
This is... MedChem .fi
Novel alpha2beta1 integrin inhibitors reveal that integrin binding to collagen under shear stress conditions does not require ... Fluorescent small molecule probe to modulate and explore alpha2beta1 integrin function. Journal of the American Chemical ... A small molecule inhibitor of integrin alpha2beta1 introduces a new strategy for antithrombotic therapy. Thrombosis and ... Blockage of Collagen Binding to Integrin alpha2beta1: Structure-activity Relationship of Protein-protein Interaction Inhibitors ...
Rockefeller University Press - Texas A&M University (TAMU) Scholar
Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through alpha2beta1 integrin.. The ... Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside- ... Modulation of calcium current in arteriolar smooth muscle by alphav beta3 and alpha5 beta1 integrin ligands.. The Journal of ... Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through 21 integrin. The Journal of ...
e-space
In the main, integrins alpha2beta1 and alphavbeta6 intervened in these processes. Using tyrphostins, it was demonstrated that ... Concomitant cell growth and differentiation are dependent on erbB1 and integrin activation in an autonomously surviving colon ... Concomitant cell growth and differentiation are dependent on erbB1 and integrin activation in an autonomously surviving colon ...
![Anti-Integrin a2 [HAS-6] | Monoclonal Antibodies - Ximbio](data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAABAAAAAQCAMAAAAoLQ9TAAAANlBMVEX4SEX4SEX4SEX4SEX4SEX4SEX4SEX4SEVHcEz4SEX4SEX4SEX4SEX4SEX4SEX4SEX4SEX4SEX6NYF0AAAAEXRSTlMC9uyFrZgJAQDBczhIYSgb3FtikdoAAACHSURBVBiVNU5LFsQwCLJtGkn/3P+yA+aNi0QFgYiEKjLSTerHyaFOU+MFLwbZxMFGIRmBixQkInkWwxA79BxTA6mjUYdpeb+LYK74LwJd89I9S9S6rxmPFEojEazqTqaAiY/c9xKpBWa/lI1PbrFf4KkgdlnJ246HnGypoDuqGrcZfbobk8YP/EEJVU07lXwAAAAASUVORK5CYII=)
Anti-Integrin a2 [HAS-6] | Monoclonal Antibodies - Ximbio
Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. ... Integrin alpha II combines with Integrin beta 1 to form the alpha2/beta1 integrin duplex. Integrins are involved in cell ... Anti-Integrin a2 [HAS-6] Invented by Prof Fiona Watt from Kings College London Invented at Cancer Research UK London Research ... Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. ...
S-Adenosyl-L-Methionine protects the probiotic yeast, Saccharomyces boulardii,from acid-induced cell death | BMC Microbiology |...
Saccharomyces boulardii improves intestinal cell restitution through activation of the alpha2beta1 integrin collagen receptor. ...
CD47 - wikidoc
Integrins. CD47 interacts with several membrane integrins, most commonly integrin avb3. These interactions result in CD47/ ... "Thrombospondin-1 acts via IAP/CD47 to synergize with collagen in alpha2beta1-mediated platelet activation". Blood. 94 (2): 642- ... Chung J, Gao AG, Frazier WA (1997). "Thrombspondin acts via integrin-associated protein to activate the platelet integrin ... 1996). "Integrin-associated protein is a receptor for the C-terminal domain of thrombospondin". J. Biol. Chem. 271 (1): 21-4. ...
Associate Professor Feng-Ting Huang
Evaluation of prognostic integrin alpha2beta1 PET tracer and concurrent targeting delivery using focused ultrasound for brain ... Integrin α2β1-targeting ferritin nanocarrier traverses the blood-brain barrier for effective glioma chemotherapy. J ... The use of PET imaging for prognostic integrin α2β1 phenotyping to detect non-small cell lung cancer and monitor drug ...
Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF (2840-A3) | Bio-Techne
Recombinant Human Integrin alpha 3 beta 1/VLA-3 Protein, CF (2840-A3) is manufactured by R&D Systems. Cited in 5 publications. ... Haidari M et al. (2012-07-25), Integrin alpha2beta1 mediates tyrosine phosphorylation of vascular endothelial cadherin induced ... Background: Integrin alpha 3 beta 1/VLA-3. VLA-3 (Very Late Antigen 3) is a member of the integrin family, beta1 subfamily, of ... Human Integrin alpha3. (Phe33-Glu991). Accession # P26006. acidic tail. Human Integrin beta1. (Glu21-Asp728). Accession # ...