*  Plus it
Inositol phosphate formation in [3H]myo-inositol-labeled cells and intracellular calcium ([Ca2+]i) mobilization in Fura 2- ... P2Y4 and P2Y6 receptor promoted a steady accumulation of inositol phosphates for up to 60 min (Figs. 2A and3A). Although the ... A, time course for inositol phosphate accumulation in the presence of 100 μM UTP (the data represent the mean ± S.E.M. from ... 2B). The EC50 values for nucleotide-promoted inositol phosphate formation in (m)P2Y4-1321N1 cells were as follows: UTP, 260 ± ...
  http://jpet.aspetjournals.org/content/297/1/43
*  Subcellular localization of the enzymes that dephosphorylate myo-inositol polyphosphates in human platelets | Biochemical...
The cytosolic Ins(1,4)P2 phosphatase hydrolyses the 1-phosphate of Ins(1,4)P2, whereas the cytosolic and membrane-bound Ins(1,4 ... The phosphatase-induced hydrolysis of [3H]inositol 1,4-bisphosphate [Ins(1,4)P2)] and [3H]inositol 1,4,5-trisphosphate [Ins(1,4 ... Subcellular localization of the enzymes that dephosphorylate myo-inositol polyphosphates in human platelets. L Molina Y Vedia, ... Subcellular localization of the enzymes that dephosphorylate myo-inositol polyphosphates in human platelets ...
  http://www.biochemj.org/content/255/3/795
*  Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes | Biochemical Journal
Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes. G M Burgess, R F Irvine, M J Berridge, J S McKinney, J ... In permeabilized hepatocytes, inositol 1,4,5-trisphosphate, inositol 2,4,5-trisphosphate and inositol 4,5-bisphosphate induced ... The order of potency was inositol 1,4,5-trisphosphate greater than inositol 2,4,5-trisphosphate greater than inositol 4,5- ... Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes Message Subject (Your Name) has forwarded a page to you ...
  http://www.biochemj.org/content/224/3/741
*  Plus it
... inositol phosphates. The carbachol-stimulated increase in [3H]inositol phosphate accumulation was not affected by pretreatment ... The accumulation of [3H]inositol monophosphate was delayed and progressively increased over 30 min. [3H]inositol 1,3,4,5- ... inositol phosphate production. The more M3 receptor-selective muscarinic antagonist pirenzepine (KB = 53 nM) was approximately ... without altering inositol 1,4,5-trisphosphate accumulation. We conclude that muscarinic receptor stimulation of inositol ...
  http://molpharm.aspetjournals.org/content/40/6/952
*  Inhibition of carbachol-induced inositol phosphate accumulation by phencyclidine, phencyclidine-like ligands and sigma agonists...
It is concluded that PCP, PCP-like compounds and sigma agonists block carbachol-induced inositol-phosphate accumulation by ... In all three regions studied, PCP significantly inhibited carbachol-induced [3H]inositol phosphate accumulation working as low ... Inhibition of carbachol-induced inositol phosphate accumulation by phencyclidine, phencyclidine-like ligands and sigma agonists ... Inhibition of carbachol-induced inositol phosphate accumulation by phencyclidine, phencyclidine-like ligands and sigma agonists ...
  http://jpet.aspetjournals.org/content/254/3/952
*  Changes in Inositol 1,4,5-Trisphosphate and Inositol 1,3,4,5-Tetrakisphosphate Mass Accumulations in Cultured Adrenal...
Histamine, which produced a larger overall total inositol phosphate response in [H-3]inositol-loaded cells, produced ... CHALLISS, R A J and JONES, J A and OWEN, P J and BOARDER, M R (1991) Changes in Inositol 1,4,5-Trisphosphate and Inositol 1,3,4 ... Here, we have used mass assays of inositol 1,4,5-trisphosphate [Ins(1,4,5)P3] and inositol 1,3,4,5-tetrakisphosphate [Ins(1,3,4 ... Changes in Inositol 1,4,5-Trisphosphate and Inositol 1,3,4,5-Tetrakisphosphate Mass Accumulations in Cultured Adrenal ...
  http://eprints.lancs.ac.uk/56101/
*  Inositol Phosphate Release and Metabolism During Myocardial Ischemia and Reperfusion in Rat Heart | Circulation Research
Ischemia for longer than 5 minutes caused a cessation of inositol phosphate production, with inositol phosphates initially ... First, total release of inositol phosphates was greater (466±37 compared with 345±29 cpm/mg protein, P,.05). Second, inositol 1 ... Inositol Phosphate Release and Metabolism During Myocardial Ischemia and Reperfusion in Rat Heart. Karen E. Anderson, Anthony M ... Inositol phosphate release and metabolism in rat left atria. Circ Res. 1995;76:252-260. ...
  http://circres.ahajournals.org/content/76/2/261
*  A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate. - Department of...
RESULTS: The derivative 2-O-benzyl-myo-inositol 1,3,4,5,6-pentakisphosphate (2-O-Bn-InsP(5)) is active towards cancer types ... We previously reported that the inhibition of Akt by inositol 1,3,4,5,6-pentakisphosphate (InsP(5)) results in anti-tumour ... Inositol Phosphates, Intracellular Signaling Peptides and Proteins, Male, Mice, Mice, Nude, Molecular Structure, Ovarian ... A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate. ...
  https://pharm.ox.ac.uk/publications/640326
*  Lithium inhibits muscarinic-receptor-stimulated inositol tetrakisphosphate accumulation in rat cerebral cortex | Biochemical...
These data are consistent with inhibition of inositol mono-, bis- and 1,3,4-tris-phosphate phosphatases to different degrees by ... inositol 1,3,4-trisphosphate ([3H]Ins(1,3,4)P3), [3H]inositol 1,4,5-trisphosphate ([3H]Ins(1,4,5)P3) and [3H]inositol ... inositol. The muscarinic agonist carbachol evoked an enhanced steady-state accumulation of [3H]inositol monophosphate ([3H] ... Lithium inhibits muscarinic-receptor-stimulated inositol tetrakisphosphate accumulation in rat cerebral cortex. I Batty, S R ...
  http://www.biochemj.org/content/247/3/797
*  AID 461509 - Activity at human 5HT2A receptor expressed in HEK293 cells assessed as [3H]inositol phosphate production by...
BioAssay record AID 461509 submitted by ChEMBL: Activity at human 5HT2A receptor expressed in HEK293 cells assessed as [3H]inositol phosphate production by scintillation counting.
  https://pubchem.ncbi.nlm.nih.gov/bioassay/461509
*  Inositol-phosphate phosphatase - Wikipedia
... inositol 1-phosphatase, L-myo-inositol-1-phosphate phosphatase, myo-inositol 1-phosphatase, inositol phosphatase, inositol ... phosphate Thus, the two substrates of this enzyme are myo-inositol phosphate and H2O, whereas its two products are myo-inositol ... an inositol-phosphate phosphatase (EC 3.1.3.25) is an enzyme that catalyzes the chemical reaction myo-inositol phosphate + H2O ... myo-inositol-1(or 4)-phosphate phosphohydrolase, myo-inositol monophosphatase, and myo-inositol-1-phosphatase. Eisenberg F Jr ( ...
  https://en.wikipedia.org/wiki/Inositol-phosphate_phosphatase
*  Inositol phosphate - Wikipedia
The group comprises: inositol monophosphate (IP) inositol bisphosphate (IP2) inositol trisphosphate (IP3) inositol ... Inositol phosphates are a group of mono- to polyphosphorylated inositols. They play crucial roles in diverse cellular functions ... Further reading: Function of calcium in humans Inositol tetra-, penta-, and hexa-phosphates have been implicated in gene ... Inositol trisphosphates act on the inositol triphosphate receptor to release calcium into the cytoplasm. ...
  https://en.wikipedia.org/wiki/Inositol_phosphate
*  Inositol Phosphates and Lipids | SpringerLink
Inositol, in its native or lipid derived forms, serves as a master building block which, when phosphorylated, leads to the ... Inositol Phosphates and Lipids: Methods and Protocols compiles many of the techniques that underscore phosphorylated inositol ... In Inositol Phosphates and Lipids: Methods and Protocols, expert researchers introduce the basic methodological tools to ... Molecular Manipulation and Analysis of Inositol Phosphate and Pyrophosphate Levels in Mammalian Cells ...
  https://link.springer.com/book/10.1007/978-1-60327-175-2
*  Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to...
Here we report that inositol phosphates (InsPs) and phosphatdidylinositol phosphates (PtdInsPs) serve as activators of IDE. ... Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to ... Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to ... Inositol phosphates and phosphoinositides activate insulin-degrading enzyme, while phosphoinositides also mediate binding to ...
  https://www.ncbi.nlm.nih.gov/pubmed/28325868?dopt=Abstract
*  Inositol Phosphate Production in the Left Ventricle following Induction of Acute Hypertension | Clinical Science
Inositol Phosphate Production in the Left Ventricle following Induction of Acute Hypertension. DH MacIver, AM Heagerty, JD ... Inositol Phosphate Production in the Left Ventricle following Induction of Acute Hypertension ... Inositol Phosphate Production in the Left Ventricle following Induction of Acute Hypertension ... Inositol Phosphate Production in the Left Ventricle following Induction of Acute Hypertension ...
  http://www.clinsci.org/content/76/s20/52P.3
*  Inositol-3-phosphate synthase - Wikipedia
... inositol 1-phosphate synthatase, glucose 6-phosphate cyclase, inositol 1-phosphate synthetase, glucose-6-phosphate inositol ... 1D-myo-inositol 3-phosphate Hence, this enzyme has one substrate, D-glucose 6-phosphate, and one product, 1D-myo-inositol 3- ... Barnett JE, Corina DL (1968). "The mechanism of glucose 6-phosphate-D-myo-inositol 1-phosphate cyclase of rat testis. The ... an inositol-3-phosphate synthase (EC 5.5.1.4) is an enzyme that catalyzes the chemical reaction D-glucose 6-phosphate ⇌ {\ ...
  https://en.wikipedia.org/wiki/Inositol-3-phosphate_synthase
*  1L-myo-inositol 1-phosphate cytidylyltransferase - Wikipedia
... inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase, the key enzyme for di-myo-inositol- ... inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1-phosphate transferase (IPCT/DIPPS)), L-myo-inositol-1- ... inositol-1-phosphate cytidylyltransferase (bifunctional CTP:inositol-1-phosphate cytidylyltransferase/CDP-inositol:inositol-1- ... CDP-1L-myo-inositol This enzyme is involved in biosynthesis of bis(1L-myo-inositol) 1,3'-phosphate. Rodrigues, M.V.; Borges, N ...
  https://en.wikipedia.org/wiki/1L-myo-inositol_1-phosphate_cytidylyltransferase
*  D-inositol-3-phosphate glycosyltransferase - Wikipedia
D-inositol-3-phosphate glycosyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH) Molecular and ... D-inositol-3-phosphate glycosyltransferase (EC 2.4.1.250, mycothiol glycosyltransferases, MshA) is an enzyme with systematic ... This enzyme catalyses the following chemical reaction UDP-N-acetyl-D-glucosamine + 1D-myo-inositol 3-phosphate ⇌ {\displaystyle ... 1D-myo-inositol 3-phosphate + UDP This enzyme catalyses the first dedicated reaction in the biosynthesis of mycothiol. Newton, ...
  https://en.wikipedia.org/wiki/D-inositol-3-phosphate_glycosyltransferase
*  Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1,25-dihydroxyvitamin D3 |...
Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1,25-dihydroxyvitamin D3. S ... Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1,25-dihydroxyvitamin D3 ... Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1,25-dihydroxyvitamin D3 ... Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1,25-dihydroxyvitamin D3 ...
  http://www.biochemj.org/content/289/3/675
*  The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization |...
... inositol phosphate; IP3K, Ins(1,4,5)P3 3-kinase; IP6K, InsP6 kinase; (Hs or Rn)IPMK, (human or rat) inositol phosphate ... Functionally important motifs [inositol phosphate-binding site, ATP-binding site, catalytically important SSLL (Ser-Ser-Leu-Leu ... It was previously reported that it is also an inositol phosphate multikinase and an important factor of the mRNA export pathway ... The human homologue of yeast ArgRIII protein is an inositol phosphate multikinase with predominantly nuclear localization. ...
  http://www.biochemj.org/content/366/2/549
*  Inositol phosphate metabolism | LAMP
1-phosphatidylinositol-4-phosphate 5-kinase. 2.7.1.68. TA19180. CDP diacylglycerol-inositol 3-phosphatidyltransferase. 2.7.8.11 ... 1-phosphatidylinositol-4-phosphate 5-kinase. 2.7.1.68. TA11845. 1-phosphatidylinositol-4-phosphate 5-kinase. 2.7.1.68. TA13405 ...
  http://www.llamp.net/?q=Ta%20Inositol%20phosphate%20metabolism
*  RANDOX 25I-NBOMe (2C-I-NBOMe, Cimbi-5) ELISA [R-NBOMe] Equl offers Enzyme Assay Kits, Reagent Mixtures, Enzymes, Glycobiology,...
Alpha Phosphate Modified NTP. * Non-Nucleotide 5' Triphosphates. * Hot Start PCR Reagent ... Inositol. * Vitamin B1 (Thiamin). * Vitamin B12 (Cyanocobalamin). * Vitamin B2 (Riboflavin). * Vitamin B3 (Niacin) ...
  http://www.equl.com/index.php?main_page=product_info&cPath=70_1541_1709&products_id=322614
*  Urinary Support-category-listing
Main IngredientSodium Phosphate Sodium Phosphate (1) * Main IngredientUrinary Support Formula Urinary Support Formula (4) ... Main IngredientInositol Inositol (1) * Main IngredientJuniper (Juniperus communis) Juniper (Juniperus communis) (1) ...
  https://www.pureformulas.com/category/urinary-support.html?N=4294961755+4294862150+4294961789+4294965620&view=listing
*  Protocols and Video Articles Authored by Rohini Kuner (Translated to Italian)
Inositol 1,4,5-triphosphate receptor 1 and myosin light chain kinase were recruited as key phosphorylation targets of ... 2011 , Pubmed ID: 21359147 Sphingosine-1-phosphate (S1P) is a key regulator of immune response. Immune cells, epithelia and ... the ability of linking mGluR1/5 to synaptic proteins and functions as an endogenous negative modulator of the mGluR1/5 inositol ...
  https://www.jove.com/author/Rohini_Kuner?language=Italian