*  Types of myeloma | Leukaemia CARE
The light chain proteins are smaller than complete immunoglobulins and show up in the blood and urine. This can be monitored ... Light chain/Bence Jones. About 1 in 5 people with myeloma (20%) do not produce complete immunoglobulins (paraproteins). They ... The serum free light chain test may pick up very low levels of paraprotein, and so can be helpful in diagnosing this type of ... This test can pick up free light chains in the blood and is easier as you don't have to collect 24 hours worth of urine every ...
  http://www.leukaemiacare.org.uk/types-of-myeloma
*  Variability of the immunoglobulin light chain in the Siberian sturgeon, Acipenser baeri
immunoglobulin; light chain; VL gene; diversity; evolution; Siberian sturgeon; Acipenser baeri; HEAVY-CHAIN; SOMATIC MUTATION; ... Variability of the immunoglobulin light chain in the Siberian sturgeon, Acipenser baeri. Lundqvist, ML Uppsala University. ...
  http://uu.diva-portal.org/smash/record.jsf?pid=diva2:105872
*  Serum free light chains, not urine specimens, should be used to evaluate response in light-chain multiple myeloma | Blood...
... chain and urine electrophoresis for the detection of the light chain component of monoclonal immunoglobulins in light chain and ... Serum free light chains, not urine specimens, should be used to evaluate response in light-chain multiple myeloma. Thomas ... Serum free light chains, not urine specimens, should be used to evaluate response in light-chain multiple myeloma. Blood, 128( ... Serum free light chains should be the target of response evaluation in light chain multiple myeloma rather than urines: results ...
  http://www.bloodjournal.org/content/128/25/2941?sso-checked=true
*  Analysis of the Immunoglobulin Light Chain Genes in Zebra Finch: Evolutionary Implications
Evidence for one immunoglobulin light-chain type in chickens: absence of a blocked N-terminal light-chain type. Biochem Genet. ... and two identical light chains (IGL). Most tetrapod species encode more than one isotype of light chains. Chicken is the only ... Analysis of the Immunoglobulin Light Chain Genes in Zebra Finch: Evolutionary Implications. Sabyasachi Das,*,1,2 Uzra Mohamedy, ... Organization of the human immunoglobulin lambda light-chain locus on chromosome 22q11.2. Hum Mol Genet. 1995;4:983-991. [PubMed ...
  http://pubmedcentralcanada.ca/pmcc/articles/PMC2877555/
*  Primary structure of a deleted human lambda type immunoglobulin light chain containing carbohydrate: protein Sm lambda
An internal molecular deletion occurring in a human lambda type immunoglobulin light (L)-chain (Sm lambda) has been defined by ... Primary structure of a deleted human lambda type immunoglobulin light chain containing carbohydrate: protein Sm lambda. ... Primary structure of a deleted human lambda type immunoglobulin light chain containing carbohydrate: protein Sm lambda. ... and light (L) chains and the hypervariable regions, are particularly susceptible to breakage and reunion. We postulate that the ...
  https://eurekamag.com/research/041/068/041068912.php
*  Novel Analysis of Clonal Diversification in Blood B Cell and Bone Marrow Plasma Cell Clones in Immunoglobulin Light Chain...
Immunoglobulin light chain amyloidosis (AL) is characterized by a limited clonal expansion of plasma cells and amyloid ... Human B cells cell differentiation repertoire development plasma cells light chain amyloidosis immunoglobulin light chain ... Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain-associated ... Immunoglobulin light chain amyloidosis (AL) is characterized by a limited clonal expansion of plasma cells and amyloid ...
  https://link.springer.com/article/10.1007%2Fs10875-006-9056-9
*  Immunoglobulin light chain gene translocations in non-Hodgkin'...
Immunoglobulin light chain gene translocations in non-Hodgkin's lymphoma as assessed by fluorescence in situ hybridisation.: In ... while a few involve the immunoglobulin light chain gene (IGL) locus, consisting of the kappa light chain gene (IGkappa) and the ... Immunoglobulin light chain gene translocations in non-Hodgkin's lymphoma as assessed by fluorescence in situ hybridisation.. ... In non-Hodgkin's lymphoma (NHL), the majority of translocations involve the immunoglobulin heavy chain gene (IGH) locus, ...
  https://www.mysciencework.com/publication/show/immunoglobulin-light-chain-gene-translocations-non-hodgkin-s-lymphoma-assessed-fluorescence-situ-hybridisation-6aeb6d05
*  "A small hypervariable segment in the variable domain of an immunoglobu" by N Sakato, M Semma et al.
A small hypervariable segment in the variable domain of an immunoglobulin light chain stimulates formation of anti-idiotypic ... "A small hypervariable segment in the variable domain of an immunoglobulin light chain stimulates formation of anti-idiotypic ...
  https://mouseion.jax.org/ssbb1982/3493/
*  Anti-Rat immunoglobulin light chain-like antibody [KT100] (ab95376) Protocols
Abcam provides specific protocols for Anti-Rat immunoglobulin light chain-like antibody [KT100] (ab95376) : Western blot ...
  http://www.abcam.com/rat-immunoglobulin-light-chain-like-antibody-kt100-ab95376-protocols.html
*  High sensitivity cardiac troponin T in patients with immunoglobulin light chain amyloidosis | Heart
High sensitivity cardiac troponin T in patients with immunoglobulin light chain amyloidosis ... High sensitivity cardiac troponin T in patients with immunoglobulin light chain amyloidosis ... assay in patients with immunoglobulin light chain amyloidosis (AL) improves risk prediction. ...
  http://heart.bmj.com/content/100/5/383
*  Immunoglobulin light chain - Wikipedia
... heavy chains and two Ig light chains. There are two types of light chain in humans: kappa (κ) chain, encoded by the ... thus the two light chains of an individual antibody are identical. Each light chain is composed of two tandem immunoglobulin ... The immunoglobulin light chain is the small polypeptide subunit of an antibody (immunoglobulin). A typical antibody is composed ... Other types of light chains can be found in lower vertebrates, such as the Ig-Light-Iota chain of Chondrichthyes and Teleostei ...
  https://en.wikipedia.org/wiki/Immunoglobulin_light_chain
*  Frontiers | Diversity of Immunoglobulin Light Chain Genes in Non-Teleost Ray-Finned Fish Uncovers IgL Subdivision into Five...
... encoding homogeneous lambda-like light chain. In addition, sterlet possesses sigma-like VL and J-CL genes, which are ... encoding homogeneous lambda-like light chain. In addition, sterlet possesses sigma-like VL and J-CL genes, which are ... The isotype described previously as the teleostean IgL lambda turned out to be a kappa and lambda chain paralog that emerged ... The isotype described previously as the teleostean IgL lambda turned out to be a kappa and lambda chain paralog that emerged ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2018.01079/full
*  Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: results of a phase II...
... urine free light chain excretion and serum free light chain ratio).. Hematologic responses were measured at three, six, nine ... Immunoglobulin light chain amyloidosis (AL) is a plasma cell dyscrasia characterized by deposition of amyloid fibrils in ... Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: results of a phase II ... Melphalan, lenalidomide and dexamethasone for the treatment of immunoglobulin light chain amyloidosis: results of a phase II ...
  http://www.haematologica.org/content/98/5/789
*  Immunoglobulin light chain gene rearrangements in precursor-B-acute lymphoblastic leukemia: characteristics and applicability...
Immunoglobulin light chain gene rearrangements in precursor-B-acute lymphoblastic leukemia: characteristics and applicability ... Immunoglobulin light chain gene rearrangements in precursor-B-acute lymphoblastic leukemia: characteristics and applicability ... Immunoglobulin light chain gene rearrangements in precursor-B-acute lymphoblastic leukemia: characteristics and applicability ... showed a good stability between diagnosis and relapse and reached good sensitivities in real-time quantitative polymerase chain ...
  http://www.haematologica.org/content/91/5/679
*  Serological Immunoglobulin-Free Light Chain Profile in Myasthenia Gravis Patients
Serological levels of free immunoglobulin light chains (FLCs), produced in excess of heavy chains during synthesis of ... Serological Immunoglobulin-Free Light Chain Profile in Myasthenia Gravis Patients. Umberto Basile,1 Mariapaola Marino,2 Cecilia ... We found a statistically significant increase in free κ chains in both AChR- and MuSK-MG patients, while free λ chain levels ... We also observed a significant reduction of both free κ and λ chains in 1/4 MuSK-MG patients along with specific abs titer, two ...
  https://www.hindawi.com/journals/jir/2018/9646209/abs/
*  Immunoglobulins devoid of light chains - Vrije, Universiteit Brussel
There is provided an isolated immunoglobulin comprising two heavy polypeptide chains sufficient for the formation of a complete ... light chain in the four-chain model immunoglobulins is that of a committed heavy chain chaperon and that the emergence of light ... As all three immunoglobulins bind to Protein A we refer to them as IgG: namely IgG1 (light chain and heavy chain γ1 (50 Kd) ... The immunoglobulins of the invention, which are devoid of light chains are such that the variable domains of their heavy chains ...
  http://www.freepatentsonline.com/5759808.html
*  Comparative hybridization studies iwth an immunoglobulin light chain mRNA fraction and non-immunoglobulin mRNA of mouse. -...
Comparative hybridization studies iwth an immunoglobulin light chain mRNA fraction and non-immunoglobulin mRNA of mouse. ... Comparative hybridization studies iwth an immunoglobulin light chain mRNA fraction and non-immunoglobulin mRNA of mouse. ... Comparative hybridization studies iwth an immunoglobulin light chain mRNA fraction and non-immunoglobulin mRNA of mouse. ... Immunoglobulin Fragments, Liver, Mice, Mice, Inbred BALB C, Myeloma Proteins, Nucleic Acid Conformation, Nucleic Acid ...
  https://www.rdm.ox.ac.uk/publications/601870
*  Detection of immunoglobulin light chain mRNA by in situ hybridisation using biotinylated tyramine signal amplification. |...
A highly sensitive method for the light microscopic in situ hybridisation of immunoglobulin light chain mRNA in formalin fixed ... kappa and lambda light chain immunoglobulin mRNA in situ hybridisation was performed with fluorescein isothiocyanate conjugated ... Detection of immunoglobulin light chain mRNA by in situ hybridisation using biotinylated tyramine signal amplification. ... Detection of immunoglobulin light chain mRNA by in situ hybridisation using biotinylated tyramine signal amplification. ...
  http://mp.bmj.com/content/52/1/47
*  Immunoglobulin Free Light Chains, Serum - Meriter Laboratories
Immunoglobulin Free Light Chains, S Useful For. Monitoring patients with monoclonal light chain diseases but no M-spike on ... Test Code SQ KLFLCM, EPIC LAB735 Immunoglobulin Free Light Chains, Serum Additional Codes. Mayo Test ID. ... Kappa Free Light Chain, S. No. Yes. LFLC. Lambda Free Light Chain, S. No. Yes. ...
  http://meriter.testcatalog.org/show/SQ-KLFLCM-EPIC-LAB735
*  123550: Immunoglobulin G (IgG) Heavy and Light Chain ... | LabCorp
For the quantitative measurement of human IgG heavy chain and light chain intact immunoglobulin in serum. The IgG HLC ratio can ... Immunoglobulin G (IgG) Heavy and Light Chain (HLC) Pairs, κ and λ With Ratio. TEST: 123550 Test number copied ... Immunoglobulin heavy/light chain ratios improve paraprotein detection and monitoring, identify residual disease and correlate ... IgG Heavy Light Chains(HLC), S. 123536. IgG K/L HLC Ratio. Ratio. 74868-1. ...
  https://www.labcorp.com/test-menu/29391/immunoglobulin-g-igg-heavy-and-light-chain-hlc-pairs-%CE%BA-and-%CE%BB-with-ratio
*  ASMscience | Lyme Borreliosis
Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme ... Genetic manipulation of spirochetes-light at the end of the tunnel. Trends Microbiol. 9:245-248.. ... Characterization of a candidate Borrelia burgdorferi β3-chain integrin ligand identified using a phage display library. Mol. ... Role of immunoglobulin G in killing Borrelia burgdorferi by the classical complement pathway. Infect. Immun. 56:314-321.. ...
  http://www.asmscience.org/content/book/10.1128/9781555816490.chap11
*  Chelators - MP Biomedicals
IgM (Mu Chain). *IgM (WM). *Light Chains. *Monkey*IgG (WM). *Mouse*IgA (WM) ...
  http://www.mpbio.com/index.php?cPath=1_6_33_223&country=223
*  Prevalence of pregnancy-relevant infections in a rural setting of Ghana | BMC Pregnancy and Childbirth | Full Text
VIDAS test for avidity of Toxoplasma-specific immunoglobulin G for confirmatory testing of pregnant women. J Clin Microbiol. ... Plasmodium parasites were detected by peripheral blood smear and light microscopy using the Field's stain technique. Serum ... Polymerase chain reaction. spp.: Species. TPPA: Treponema pallidum particle assay. VDRL: Veneral disease research laboratory ...
  https://bmcpregnancychildbirth.biomedcentral.com/articles/10.1186/s12884-017-1351-3
*  HLA supertype variation across populations: new insights into the role of natural selection in the evolution of HLA-A and HLA-B...
As the main-chain atoms of pocket B residues 24, 25, and 34 are part of the protein backbone, and their side chains are not ... The light gray section of the bars represents the number of populations where the referred supertype was not detected ... to cytotoxic T lymphocytes and also functioning as ligands for the killer immunoglobulin-like receptor (KIR) of natural killer ...
  https://link.springer.com/article/10.1007/s00251-015-0875-9
*  Plasma cell - Wikipedia
Primary amyloidosis (AL) is caused by the deposition of excess immunoglobulin light chains which are secreted from plasma cells ... Plasma cells can only produce a single kind of antibody in a single class of immunoglobulin. In other words, every B cell is ... Plasma cells are large lymphocytes with a considerable nucleus-to-cytoplasm ratio and a characteristic appearance on light ... Educational Resource on the Biology of Immunoglobulins. *Histology image: 21001loa - Histology Learning System at Boston ...
  https://en.wikipedia.org/wiki/Plasma_cells