*  Abraham, David - Philadelphia University + Thomas Jefferson University - Thomas Jefferson University
... to kill parasites and to identify the immune evasion mechanisms used by the parasites. Vaccine development against parasitic ... basis of the vaccines will the combination of recombinant antigens with adjuvants capable of inducing specific types of immune ...
  http://www.kimmelcancercenter.org/university/jmc/departments/microbiology/faculty_staff/faculty/abraham.html
*  Frontiers | NK cells and poxvirus infection | Immunology
This review focuses on recent advances in understanding the role of NK cells in the immune response to poxviruses, the ... and the viral evasion strategies poxviruses employ to avoid the NK response. ... This review focuses on recent advances in understanding the role of NK cells in the immune response to poxviruses, the ... Not only do we realize viruses have many immune evasion strategies to escape NK cell responses, but that stimulation of NK cell ...
  https://www.frontiersin.org/articles/10.3389/fimmu.2013.00007/full
*  Immune Evasion Mechanisms in the Pathogenesis of Trypanosomatid Infections | Frontiers Research Topic
... and on the expression of the virulence factors involved in the immune evasion mechanisms of the host and on the pathogenesis of ... Keywords: Infection, Parasitic Pathogens, Pathogenesis, Virulence Factors, Immune Evasion, Trypanosoma cruzi, Trypanosoma ... and on the expression of the virulence factors involved in the immune evasion mechanisms of the host and on the pathogenesis of ... brucei, Leishmania sp, Parasite infection, parasite pathology, Parasite imune evasion, Parasite imune recognition, ...
  https://www.frontiersin.org/research-topics/5921/immune-evasion-mechanisms-in-the-pathogenesis-of-trypanosomatid-infections
*  JCI - Extracellular vesicles and infectious diseases: new complexity to an old story
... or that serve as regulators of host defense and mediators of immune evasion. These molecules may include proteins, nucleic ... whereas their involvement in immune evasion mechanisms is prominent among pathogens that establish chronic infection and is ... gp63, which can block T cell activation or induce apoptosis of immune effector cells. Exosomes from M.. tuberculosis. - or ... These exosomes and other extracellular vesicles can inhibit an immune response and likely do so through multiple mechanisms ...
  https://www.jci.org/articles/view/81132/figure/1
*  Specific Targeting of the EBV Lytic Phase Protein BNLF2a to the Transporter Associated with Antigen Processing Results in...
Immune evasion by BNLF2a was examined functionally using TAP-dependent peptide translocation assays (Fig. 5⇑B) and flow ... A CD8+ T cell immune evasion protein specific to Epstein-Barr virus and its close relatives in Old World primates. J. Exp. Med. ... These results show that BNLF2a functions as an immune evasion protein in B cells, a natural host cell for EBV infection, and ... We therefore first verified that BNLF2a expression also yielded an HLA class I immune evasion phenotype in B cells. A wild-type ...
  http://www.jimmunol.org/content/182/4/2313.long
*  Infiltration of Regulatory T Lymphocytes Impair Clinical Outcome in Ovarian Cancer Patients | MedCrave
... when they increase in the tumor microenvironment they become a part of the evasion mechanisms of the antitumor immune response ... cells may participate in mediating a suppressive microenvironment in tumor tissue and contribute to tumor evasion from immune ... Therefore, it was proved that they had differences in the tumor immune cells infiltration and it was possible that, on these ... Sakaguchi S, Miyara M, Costantino CM, Hafler DA (2010) FOXP3+ regulatory T cells in the human immune system. Nat Rev Immunol 10 ...
  http://googlescholar.medcraveonline.com/scholars/article_fulltext/6058
*  Burkitt Lymphoma: Pathogenesis and Immune Evasion
... with a specific focus on molecular targeted agents and novel immune therapies. ... Burkitt Lymphoma: Pathogenesis and Immune Evasion. Jason M. God and Azizul Haque ... or attenuation of cellular network and immune recognition or evasion will be summarized. We will also discuss the various ... its ability to mask itself from the immune system makes BL an intriguing disease to study. In this paper, we will provide an ...
  https://www.hindawi.com/journals/jo/2010/516047/abs/
*  Persistent Viral Infections and Immune evasion | Institut Pasteur
... with a particular focus on persistent viruses and the mechanisms by which viruses escape from the immune system. This specific ... Because of potent immune evasion mechanisms, and the ability of the virus to persist in immune competent hosts, a vast majority ... HomeInternationalInternational coursesInternational courses 2018Persistent Viral Infections and Immune evasion ... A new approach for deciphering complex immune responses. *A new mechanism used by group B Streptococcus to evade the host ...
  https://www.pasteur.fr/en/international/international-courses/international-courses-2018/persistent-viral-infections-and-immune-evasion
*  Preventing EBV immune evasion | Disease Models & Mechanisms
... the yeast-based assay as an effective cell-based screening approach for compounds that interfere with EBV immune evasion and ... thereby suppressing the production of antigenic peptides that the human immune system recognises as foreign. Here, Blondel et ...
  http://dmm.biologists.org/content/7/4/e0201
*  JCI - STAT3-enhancing germline mutations contribute to tumor-extrinsic immune evasion
Thus, STAT3-enhancing germline receptor variants contribute to immune evasion through their pleiotropic functions in immune ... Immune evasion and the suppression of anti-tumor responses during cancer progression are considered hallmarks of cancer and are ... Although the molecular basis for the crosstalk between tumor and immune cells is an area of active investigation, whether host- ...
  https://jci.org/articles/view/96708/pdf
*  Allosteric inhibition of complement function by a staphylococcal immune evasion protein. - PubMed - NCBI
The complement system is a major target of immune evasion by Staphylococcus aureus. Although many evasion proteins have been ... Allosteric inhibition of complement function by a staphylococcal immune evasion protein.. Chen H1, Ricklin D, Hammel M, Garcia ... Allosteric inhibition of complement function by a staphylococcal immune evasion protein. Proc Natl Acad Sci U S A. 2010 Oct 12; ... Allosteric inhibition of complement function by a staphylococcal immune evasion protein. Proc Natl Acad Sci U S A. 2010 Oct 12; ...
  https://www.ncbi.nlm.nih.gov/pubmed/20876141
*  Viruses | Free Full-Text | Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins
NS1 and NS4B proteins are involved in immune evasion. This review discusses the interplay between viral non-structural ... immune evasion; emergence flavivirus; HCV; non-structural protein; immune evasion; emergence ... Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins. Shun Chen 1,2,3,†,* , Zhen Wu 1,†. ... Chen, S.; Wu, Z.; Wang, M.; Cheng, A. Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins. Viruses 2017, 9, ...
  http://www.mdpi.com/1999-4915/9/10/291
*  Cancers | Free Full-Text | Immune Evasion in Pancreatic Cancer: From Mechanisms to Therapy
Interestingly, preclinical data have highlighted the importance of this immune evasion as the source of resistance to single ... trying to understand the immunosuppressive factors that play a part in the strong immune evasion that characterizes PDA. The ... Here, we will discuss the molecular mechanisms involved in PDA immune escape as well as the state of the art of the PDA ... the focus on the stroma of pancreatic cancer has interestingly moved from activated fibroblasts to the immune compartment, ...
  http://www.mdpi.com/2072-6694/10/1/6
*  Plasmodia Immune Evasion Flashcards - PHVTD | Brainscape
Non-variation implies it has a highly conserved function or is not very visible to the immune system. ... Blood - AMA1 MSP1 induce solid immune protection but are allele specific.. Sexual stages - TBVs ... It has antigenic escape residues that can change to escape the immune response. ... the erythrocyte moving around the body thus evading the liver and the spleen and preventing it from being detected by immune ...
  https://www.brainscape.com/flashcards/plasmodia-immune-evasion-2323878/packs/4042660
*  Abstract IA18: Latency and immune evasion of metastatic stem cells | Cancer Research
Abstract IA18: Latency and immune evasion of metastatic stem cells Message Subject (Your Name) has forwarded a page to you from ... Latency and immune evasion of metastatic stem cells. [abstract]. In: Proceedings of the AACR Special Conference: Function of ... Abstract IA18: Latency and immune evasion of metastatic stem cells. Joan Massagué ... Abstract IA02: Immune checkpoint blockade in cancer therapy: New insights and opportunities, and prospects for cures ...
  http://cancerres.aacrjournals.org/content/76/15_Supplement/IA18
*  Innate immune evasion strategies against Cryptococcal meningitis caused by Cryptococcus neoformans (Review)
... *Authors: *Cheng‑ ... Innate immune system evasion. C. neoformans has a number of established virulence factors, including polysaccharide capsules ... Innate immune responses restrict the growth and invasion of C. neoformans in mammalian hosts (16). Innate immune cells are the ... Yang, C., Wang, J., & Zou, L. (2017). Innate immune evasion strategies against Cryptococcal meningitis caused by Cryptococcus ...
  https://www.spandidos-publications.com/etm/14/6/5243
*  Immune evasion: Who needs it? | Mystery Rays from Outer Space
I said how disconcerting it was to learn that immune evasion genes of mouse cytomegalovirus really don't seem to have ... Immune evasion: Who needs it? By iayork. Last time I talked about immune evasion, I said how disconcerting it was to learn that ... Does immune evasion allow rapid HIV progression? , Mystery Rays from Outer Space says: May 4th, 2010 at 6:48 am ... The first example of viral T cell immune evasion to de described, as far as I know, was in adenovirus: 2 A glycoprotein in the ...
  http://www.iayork.com/MysteryRays/2007/08/06/33/
*  Viruses | Free Full-Text | Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain...
Herein we propose to call this unique structural scaffolding the PIE (Poxvirus Immune Evasion) domain. PIE domain containing ... Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these ... viral immune evasion; chemokine and cytokine decoy receptors poxvirus; PIE domain; SECRET domain; viral immune evasion; ... Structural Conservation and Functional Diversity of the Poxvirus Immune Evasion (PIE) Domain Superfamily. Christopher A. Nelson ...
  http://www.mdpi.com/1999-4915/7/9/4873
*  The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion | Science
The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion ... The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion ... The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion ... The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion ...
  http://science.sciencemag.org/content/358/6365/888
*  Does immune evasion allow rapid HIV progression?
Evidence for a functional role of MHC class I immune evasion? ... Does immune evasion allow rapid HIV progression? By iayork. I ... One Response to "Does immune evasion allow rapid HIV progression?" 1 Understanding HIV Transmission , Health says: May 7th, ... Now there's another paper5 showing a function for the MHC class I immune evasion ability of HIV (actually for SIV, but again ... This entry is filed under Immune evasion, Immunology, MHC, Science, Virology. You can follow any responses to this entry ...
  http://www.iayork.com/MysteryRays/2010/05/04/does-immune-evasion-allow-rapid-hiv-progression/
*  Host Immune Evasion by Lyme and Relapsing Fever Borreliae: Findings to Lead Future Studies for Borrelia miyamotoi
This article compares the physiology and immune system survival mechanisms of B. miyamotoi compared to other strains of ... Host Immune Evasion by Lyme and Relapsing Fever Borreliae: Findings to Lead Future Studies for Borrelia miyamotoi. * ... Host Immune Evasion by Lyme and Relapsing Fever Borreliae: Findings to Lead Future Studies for Borrelia miyamotoi.. Front ... as well as the current state of understanding immune evasion by B. miyamotoi.. Source: By Stone BL and Brissette CA. ...
  http://www.prohealth.com/library/showArticle.cfm?libid=29959
*  Effective immune evasion (Influenza vs. Interferon: The grudge match)
My last couple mentions of viral immune evasion of T cells may have left the impression that immune evasion in general has a ... of viral immune evasion genes that are important, or essential, for virulence. One example is influenza virus's evasion of ... of immune evasion that do have a very large effect on the virus's virulence. The example I mentioned before was influenza virus ... Immune evasion as a vaccine target , Mystery Rays from Outer Space says: October 13th, 2008 at 9:28 am ...
  http://www.iayork.com/MysteryRays/2007/08/08/effective-immune-evasion-influenza-vs-interferon-the-grudge-match/
*  Epithelial-Mesenchymal Transition and Immune Evasion during Lung Cancer Progression: The Chicken or the Egg? | Clinical Cancer...
Immune evasion is required for tumor progression and is characterized by an ineffective antitumor immune response and ... Epithelial-Mesenchymal Transition and Immune Evasion during Lung Cancer Progression: The Chicken or the Egg?. Ila Datar and ... Immune evasion is a key aspect of malignant tumor progression and is characterized by either the absence of detectable ... The balance between tumor inflammation and immune evasion is considered to be a dynamic process and solid tumors can display ...
  http://clincancerres.aacrjournals.org/content/22/14/3422
*  An Overview of the Immune Evasion Strategies Adopted by Different Viruses with Special Reference to Classical Swine Fever Virus...
An Overview of the Immune Evasion Strategies Adopted by Different Viruses with Special Reference to Classical Swine Fever Virus ... It is well established that the viruses have evolved wide variety of immune evasion strategies viz., evasion by noncytocidal ... 7. Immune evasion and immunopathogenesis of CSF. CSF virus (CSFV) has high affinity for vascular endothelial cells and ... 2. Newer concepts in the evasion of host deffense by viruses. The main sensors of the innate immune response are pattern ...
  https://www.intechopen.com/books/viral-replication/an-overview-of-the-immune-evasion-strategies-adopted-by-different-viruses-with-special-reference-to-/
*  ASMscience | Lyme Borreliosis
The plethora of inbred mouse strains, including genetically modified animals, and the depth of knowledge of the murine immune ... Immune evasion of Borrelia burgdorferi by acquisition of human complement regulators FHL-1/reconectin and factor H. Eur. J. ... CD8_ T cells are activated during the early Th1 and Th2 immune responses in the murine Lyme disease model. Infect. Immun. 65: ... Immune complexes and the evolution of Lyme arthritis: dissemination and localization of abnormal C1q binding activity. N. Engl ...
  http://www.asmscience.org/content/book/10.1128/9781555816490.chap11