*  PLOS Genetics: U87MG Decoded: The Genomic Sequence of a Cytogenetically Aberrant Human Cancer Cell Line
... indels), and translocations. We found 2,384,470 SNVs, 191,743 small indels, and 1,314 large structural variations. Known gene ... models were used to predict the effect of these mutations on protein-coding sequence. Mutational analysis revealed 512 genes ... The major mutational mechanisms in this brain cancer cell line are small indels and large structural variations. The genomic ... homozygously mutated, including 154 by SNVs, 178 by small indels, 145 by large microdeletions, and up to 35 by interchromosomal ...
  http://journals.plos.org/plosgenetics/article/comments?id=10.1371/journal.pgen.1000832
*  PLOS Genetics: U87MG Decoded: The Genomic Sequence of a Cytogenetically Aberrant Human Cancer Cell Line
... indels), and translocations. We found 2,384,470 SNVs, 191,743 small indels, and 1,314 large structural variations. Known gene ... and accurate mutational analysis of the U87MG genome comprehensively identifies different classes of genetic mutations ... The major mutational mechanisms in this brain cancer cell line are small indels and large structural variations. The genomic ... Mutational analysis revealed 512 genes homozygously mutated, including 154 by SNVs, 178 by small indels, 145 by large ...
  http://journals.plos.org/plosgenetics/article/figure?id=10.1371/journal.pgen.1000832.g006
*  PathogenSeq: TBDR
Mon Feb 13 15:00:07 2017: Finding mutations. Mon Feb 13 15:00:40 2017: Finalising results. Mon Feb 13 15:00:41 2017: End. ... Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG ...
  http://tbdr.lshtm.ac.uk/?page=results&id=58a1c9d9e6f02&name=58a1c9d9e6f02
*  Celemics, Inc. | mRNA Sequencing
또한 mRNA에 존재하는 SNV(Single Nucleotide Variant), InDel(Insertion/Deletion), Gene Rearrangement 를 관찰할 수 있습니다. ... Somatic Mutation Cancer Kit , Hereditary Cancer Kit NGS Library Preparation Kit , Library Preparation Kit ...
  http://celemics.com/service/next-generation-sequencing/mrna-sequencing
*  PathogenSeq: TBDR
Mon Feb 13 09:33:09 2017: Finding mutations. Mon Feb 13 09:33:18 2017: Finalising results. Mon Feb 13 09:33:19 2017: End. ... Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG ...
  http://tbdr.lshtm.ac.uk/?page=results&id=58a17d47e3596&name=58a17d47e3596
*  PathogenSeq: TBDR
Tue Feb 14 13:04:04 2017: Finding mutations. Tue Feb 14 13:04:13 2017: Finalising results. Tue Feb 14 13:04:14 2017: End. ... Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG ...
  http://tbdr.lshtm.ac.uk/?page=results&id=58a30033e9e26&name=58a30033e9e26
*  PathogenSeq: TBDR
Mon Feb 13 16:33:09 2017: Finding mutations. Mon Feb 13 16:34:03 2017: Finalising results. Mon Feb 13 16:34:04 2017: End. ... Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG ...
  http://tbdr.lshtm.ac.uk/?page=results&id=58a1dfa365f58&name=58a1dfa365f58
*  PathogenSeq: TBDR
Wed Mar 1 22:52:16 2017: Finding mutations. Wed Mar 1 22:52:45 2017: Finalising results. Wed Mar 1 22:52:46 2017: End. ... Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG ...
  http://tbdr.lshtm.ac.uk/?page=results&id=58b75081c9287&name=58b75081c9287
*  PathogenSeq: TBDR
Thu Feb 2 07:33:48 2017: Finding mutations. Thu Feb 2 07:33:48 2017: Finalising results. Thu Feb 2 07:33:49 2017: End. ... Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG ...
  http://tbdr.lshtm.ac.uk/?page=results&id=5892e0dc60aea&name=5892e0dc60aea
*  PathogenSeq: TBDR
Wed Feb 15 11:07:57 2017: Finding mutations. Wed Feb 15 11:08:22 2017: Finalising results. Wed Feb 15 11:08:23 2017: End. ... Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG ...
  http://tbdr.lshtm.ac.uk/?page=results&id=58a4366783461&name=58a4366783461
*  PathogenSeq: TBDR
Thu Mar 2 19:56:40 2017: Finding mutations. Thu Mar 2 19:57:35 2017: Finalising results. Thu Mar 2 19:57:36 2017: End. ... Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG ...
  http://tbdr.lshtm.ac.uk/?page=results&id=58b878c228757&name=58b878c228757
*  Application # 2016/0300013. METHOD FOR SIMULTANEOUS DETECTION OF GENOME-WIDE COPY NUMBER CHANGES, cnLOH, INDELS, AND GENE...
Detection of Mutations and Indels [0135] The high read depth allowed for the detection of single point mutations and indels in ... Identification of mutations and indels in Agilent SureCall software showing a 26-bp indel (on the right) and a heterozygous SNP ... METHOD FOR SIMULTANEOUS DETECTION OF GENOME-WIDE COPY NUMBER CHANGES, cnLOH, INDELS, AND GENE MUTATIONS Abstract. Provided ... 0124] The SNP calling algorithm SNPPET was used to call point mutations and indels (see, e.g., US Patent Application ...
  http://patents.com/us-20160300013.html
*  A System for Dosage-Based Functional Genomics in Poplar | Plant Cell
... indel mutations). Using high-precision dosage analysis, we detected indel mutations in ∼55% of the progeny. These indels varied ... A) For each chromosome, indel mutations are tiled across their length. Indel mutations vary in length (up to a whole chromosome ... A) Determination of the parental origin of each indel mutation. For each indel mutation identified (Figure 1), the percentage ... B) Density of indel mutations across the poplar genome. All indel mutations were pooled together, except for whole-chromosome ...
  http://www.plantcell.org/content/27/9/2370.full?sid=94ff4db9-637d-41ed-acb6-4d2a6a3e9c10
*  Nilesh Banavali, Ph.D.
Dynamic mechanisms behind indel mutations and their sequence dependence in nucleic acid replication:. Base pairing, or its ... We have recently delineated the underlying 3D strand slippage mechanism by which a single base insertion or deletion (indel) ... the possibility of specific non-canonical interactions providing a direct mechanism for sequence dependence of indel mutations ... Banavali, JACS, 2013). This work is being applied to understand the introduction of such mutations during strand extension by ...
  https://www.wadsworth.org/print/senior-staff/nilesh-banavali
*  GoldenPiCS: a Golden Gate-derived modular cloning system for applied synthetic biology in the yeast Pichia pastoris | BMC...
Indel mutation screenings with CRISPR/Cas9-BB3's were done in a CBS7435(MutS) strain stably expressing eGFP under control of ... InDel mutations using CRISPR/Cas9. Targeting efficiency of the modular CRISPR/Cas9 system on native sequences was evaluated by ... 2018.) This allowed rapid optimization of a CRISPR/Cas9-BB3 for efficient InDel mutations in P. pastoris within a short time. ... After restreaking the clones two times on selective agar plates the targeted loci were checked for InDel mutations by colony ...
  https://bmcsystbiol.biomedcentral.com/articles/10.1186/s12918-017-0492-3
*  John A McGrath
Novel indel mutation of STS underlies a new phenotype of self-healing recessive X-linked ichthyosis.. Authors:. Takuya Takeichi ... Novel TGM5 mutations in acral peeling skin syndrome.. Authors:. Jaap J A J van der Velden Michel van Geel Ruud G L Nellen ... Mutations in KLHL24 Add to the Molecular Heterogeneity of Epidermolysis Bullosa Simplex.. Authors:. John Y W Lee Lu Liu Chao- ... ATR gene mutations in HPV negative oropharyngeal cancer.. Authors:. Jean-Pierre Jeannon Akio Tanaka Selvam Thavaraj Teresa ...
  https://www.pubfacts.com/author/John+A+McGrath
*  RNA cytosine methyltransferase Nsun3 regulates embryonic stem cell differentiation by promoting mitochondrial activity |...
Several colonies were expanded and screened for indel mutations in Nsun3 exon 6. To this end, PCR (NSUN3fw 5′ ... Nsun3 mutation affects Wnt signalling and production of mitochondrial ROS in ESCs. In search for potential causes of the ... Nsun2 also plays an important role in this process, as its mutation was shown to delay differentiation of skin and testis in ... if Nsun3 mutation affects stem cell features of ESCs. Analysis of expression levels of the major pluripotency markers Oct4, ...
  https://link.springer.com/article/10.1007/s00018-017-2700-0
*  Examples of global statistics for a given project. Grap | Open-i
C) Distribution of indel sizes. Mentions: This section also provides graphical outputs comparing the average heterozygosity of ... indels) in many plant species. The rapidly increasing amount of re-sequencing and genotyping data generated by large-scale ... indels) in many plant species. The rapidly increasing amount of re-sequencing and genotyping data generated by large-scale ... SNiPlay detects SNPs and indels events and outputs submission files for the design of Illumina's SNP chips. Subsequently, it ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3102043_1471-2105-12-134-4&req=4
*  Construction and evolution of an Escherichia coli strain relying on nonoxidative glycolysis for sugar catabolism | PNAS
... and three synonymous amino acid mutations (SI Appendix, Table S4). Finally, there were three Indel mutations and four genome ... There are multiple mutations accumulated in the evolution of the NOG strains. The minimal set of the mutations that are ... Potential Beneficial Mutations for the Growth Phenotype of the NOG Strains.. In NOG6, part of the synthetic pck promoter (PLlac ... A point mutation in pta (V14F) was also identified in NOG6, which was not present in PHL13. To examine the effect of this ...
  http://www.pnas.org/content/115/14/3538
*  SOS1 domain structure and location of residues altered | Open-i
INDEL Mutation/genetics. *Introns. *Male. *Mitogen-Activated Protein Kinase Kinases/genetics. *Mutation ... Residue Asp309 (uncharacterized mutation p.Asp309Tyr) is shown in purple. Affected residues are listed in Supp. Table S2. ... Residue Asp309 (uncharacterized mutation p.Asp309Tyr) is shown in purple. Affected residues are listed in Supp. Table S2. ... Bottom Line: Here, we explored further the spectrum of SOS1 mutations and their associated phenotypic features.Two previously ...
  https://openi.nlm.nih.gov/detailedresult.php?img=PMC3118925_humu0032-0760-f1&req=4
*  METHODS AND COMPOSITIONS FOR RNA-GUIDED TREATMENT OF HIV INFECTION - TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER...
... after LTR-C-induced indel mutation at the 96/102 sites, a 290 bp band (middle arrow) after LTR-D-induced mutations at the 372 ... or substitution mutation or a combination of such mutations). One or more of the substitution mutations can be a substitution ( ... 3B) and no indel mutations as verified by Sanger sequencing. PCR genotyping using primers targeting Cas9 and U6-LTR showed that ... 10B is a SURVEYOR assay that shows indel mutations (arrow) in the on-target LTR genome of Cas9/LTR-A/B transfected cells. J-Lat ...
  http://www.freepatentsonline.com/y2016/0250300.html
*  "Using gene expression databases for classical trait QTL candidate gene" by Lu Lu, Lai Wei et al.
Although Tnni1 protein differences could not be confirmed, a 273 bp indel polymorphism was discovered 1 Kb upstream of the ... Animals; Blotting, Western; *Databases, Genetic; *Gene Expression Profiling; INDEL Mutation; Mice; Mice, Inbred C57BL; Mice, ... Although Tnni1 protein differences could not be confirmed, a 273 bp indel polymorphism was discovered 1 Kb upstream of the ...
  https://escholarship.umassmed.edu/oapubs/2275/
*  Preauricular | definition of preauricular by Medical dictionary
A NOVEL INDEL MUTATION IN THE TCOF1 GENE FOUND IN A NEWBORN WITH TREACHER COLLINS SYNDROME ...
  https://medical-dictionary.thefreedictionary.com/preauricular
*  Produktübersicht anti-Adracalin Antikörper
Triple A syndrome with a novel indel mutation in the AAAS gene and delayed puberty. ... Sequencing of the AAAS gene detected a compound heterozygous mutation consisting of a novel mutation p.Ser296Tyr (c.887C>A) in ... In all children with mutation in AAAS gene, regular follow up of adrenal function is necessary to avoid adrenal crisis and ... The compromising c.43C>A mutation is predicted to cause a p.Gln15Lys amino acid substitution in the ALADIN protein. ...
  http://www.antikoerper-online.de/abstract/Achalasia%2C+Adrenocortical+Insufficiency%2C+Alacrimia+