Effect of Phosphatidylcholine on Plasma Homocysteine in Healthy Volunteers - Tabular View - ClinicalTrials.gov
A high homocysteine concentration is a potential risk for cardiovascular disease. Plasma homocysteine concentrations can be ... Effect of Phosphatidylcholine on Plasma Homocysteine in Healthy Volunteers. Official Title ICMJE Effect of Choline Supplemented ... Effect of Phosphatidylcholine on Plasma Homocysteine in Healthy Volunteers. This study has been completed. ... If supplementation with choline or phosphatidylcholine, the form in which choline occurs in foods, lowers homocysteine ...https://clinicaltrials.gov/ct2/show/record/NCT00102232
Homocysteine Study (HOST) - Full Text View - ClinicalTrials.gov
Homocysteine lowering and cognition in CKD: the Veterans Affairs homocysteine study. Am J Kidney Dis. 2009 Sep;54(3):440-9. doi ... Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal ... Patients will be screened by their plasma homocysteine concentration. They must have a level of at least 15 uM/L to be enrolled ... Patients will be screened by their plasma homocysteine concentration. They must have a level of at least 15 mM/L to be enrolled ...https://clinicaltrials.gov/ct2/show/study/NCT00032435?show_desc=Y
High Homocysteine Levels May Double Risk of Dementia, Alzheimer's Disease, New Report Suggests
The relationship between AD and the amino acid homocysteine is of particular interest because blood levels of homocysteine can ... High Homocysteine Levels May Double Risk of Dementia, Alzheimer's Disease, New Report Suggests (SafetyAlerts) - People with ... The association between homocysteine and AD was found to be strong and independent of other factors, such as age, gender, APOE ... Elevated homocysteine levels (defined as greater than 14 mmol/liter) doubled the chance that a participant would develop AD and ...http://www.safetyalerts.com/g/alzheimers.html
Plasma homocysteine levels in patients with deep venous thromb...
Plasma homocysteine levels in patients with deep venous thrombosis.: Increased risk of arterial and venous thromboembolic ... Plasma homocysteine levels in patients with deep venous thrombosis.. Authors * Amundsen, T ...https://www.mysciencework.com/publication/show/plasma-homocysteine-levels-patients-deep-venous-thrombosis-db8ba3a0
Effect of Dexrazoxane on Homocysteine-Induced Endothelial Dysfunction in Normal Subjects | Arteriosclerosis, Thrombosis, and...
Homocysteine-induced endothelial cell injury in vitro: a model for the study of vascular injury. Thromb Res. 1980; 18: 113-121. ... Homocysteine-mediated cellular toxicity may be dependent in part on interactions with intracellular LMW-Fe2+. Nearly all iron ... After placebo, oral methionine increased plasma homocysteine (from 5.1±0.4 μmol/L at baseline to 14.2±1.3 μmol/L at 4 hours, P, ... Homocysteine and Oxidative Stress. The effects of dexrazoxane on vascular endothelial function were determined in a model of ...http://atvb.ahajournals.org/content/22/7/e15
Plasma homocysteine and markers for oxidative stress and inflammation in patients with coronary artery disease - a prospective...
... suggesting that homocysteine per se does not cause increased lipid peroxidation. Levels of plasma ICAM-1 and S-AA were ... Elevated plasma levels of total homocysteine (tHcy) are associated with an increased risk of developing occlusive vascular ... Plasma total homocysteine and hospitalizations for cardiovascular disease: the Hordaland Homocysteine Study. Arch Intern Med ... Vitamin supplementation normalizes total plasma homocysteine concentration but not plasma homocysteine redox status in patients ...https://www.degruyter.com/view/j/cclm.2005.43.issue-6/cclm.2005.108/cclm.2005.108.xml
IBIMA Publishing Plasma Homocysteine Concentrations in Dogs
"Homocysteine Measurement by an Enzymatic Method and Potential Role of Homocysteine as a Biomarker in Dogs," The Journal of ... Sex and Homocysteine Concentration. The mean plasma Hcy concentrations of the male and female dogs were 16.1 ± 0.6 Î¼mol/l ( ... Disease and Homocysteine Concentration. Dogs in the heart disease, neoplastic disease, kidney disease, and skin disease groups ... Breed and Homocysteine Concentration. Breed-specific plasma Hcy concentrations are summarized in Table 1. Breeds are only ...http://ibimapublishing.com/articles/IJVMR/2014/141449/
2002 - Elevated plasma total homocysteine levels increased the risk for dementia in the elderly | 2002 Sep-Oct :...
Elevated plasma total homocysteine levels increased the risk for dementia in the elderly. PDF. ACP J Club. 2002 Sept-Oct;137:76 ... Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N Engl J Med. 2002 Feb 14;346:476-83. [PubMed ID: ... deviation in the log-transformed baseline plasma total homocysteine levels. Hyperhomocysteinemia (plasma homocysteine , 14 µmol ... 1. Kalmijn S, Launer LJ, Lindemans J, et al. Total homocysteine and cognitive decline in a community-based sample of elderly ...http://acpjc.org/Content/137/2/issue/ACPJC-2002-137-2-076.htm
Tips From Other Journals - American Family Physician
Interventional studies with homocysteine-lowering therapy are currently in progress. Homocysteine may not be as harmful to the ... Homocysteine, a risk factor for coronary artery disease or not? A meta-analysis. Am J Cardiol. November 1, 2000;86:1005-9. ... The role of homocysteine in the long-term progression of atherosclerosis and CAD maybe overshadowed by other risk factors such ... However, persons with elevated homocysteine levels may have less healthy lifestyles, which is itself a risk factor for CAD. ...https://www.aafp.org/afp/2001/0501/p1829.html
ADHD treatments: 2010
The conversion of homocysteine to cysteine is (largely) irreversible. This is good news if we want to "dump off" homocysteine ... If this SAMe to homocysteine conversion process is not kept in check, we run the potential risk of homocysteine buildup. ... To summarize: if we want to keep the "cycle" going to avoid homocysteine buildup by converting homocysteine to methionine, we ... Elevated homocysteine levels have been linked from everything from cancer to diabetes to autoimmune disorders to stroke ( ...http://adhd-treatment-options.blogspot.com/2010/
Elevated Fasting Total Plasma Homocysteine Levels and Cardiovascular Disease Outcomes in Maintenance Dialysis Patients |...
A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. JAMA.. 1995;274:1049-1057. ... Bostom AG, Brosnan JT, Hall B, Nadeau MR, Selhub J. Net uptake of plasma homocysteine by the rat kidney in vivo. ... Folate status is the major determinant of fasting total plasma homocysteine levels in maintenance dialysis patients. ... Elevated Fasting Total Plasma Homocysteine Levels and Cardiovascular Disease Outcomes in Maintenance Dialysis Patients. A ...http://atvb.ahajournals.org/content/17/11/2554
MTHFR polymorphisms and serum cobalamin affect plasma homocysteine concentrations differentially in females and males
... Nilsson ... MTHFR genotypes, haplotypes, total homocysteine, folate, cobalamin, nutrigenetics National Category Medical Bioscience ... on total plasma homocysteine concentrations (tHcy). Genotyping was performed with Pyrosequencing(R) technology. The MTHFR 677T- ...http://umu.diva-portal.org/smash/record.jsf?pid=diva2:779291
Elevated homocysteine levels increase risk of heart disease and dementia
NaturalHealth365) Find out why elevated homocysteine levels dramatically increase your risk of a heart attack and stroke. Get a ... Homocysteine is a non-protein amino acid that is synthesized in the body from the amino acid methionine. Homocysteine levels ... Warning: Elevated homocysteine raises your risk of premature death. Research has shown that high homocysteine is associated ... Elevated homocysteine levels increase risk of heart disease, stroke and dementia. Posted by: Lori Alton, staff writer in ...https://www.naturalhealth365.com/homocysteine-dementia-2340.html
Parkinson's Disease: Hyperhomocysteinemia & The Levodopa Connection | The Natural Health Blogger
admin 1 Comment B Vitamins Parkinsons Disease, Homocysteine & Levodopa, Hyperhomocysteinemia Parkinsons Disease, MTHFR ... 1] [Homocysteine and its role in pathogenesis of Parkinson's disease and other neurodegenerative disorders]. ... A number of studies have now confirmed that treatment with the medication Levodopa leads to an increase in homocysteine levels ... 2] Elevated homocysteine levels in Parkinson's Disease: is there anything besides L-dopa treatment? ...http://thenaturalhealthblogger.com/2017/07/12/parkinsons-disease-hyperhomocysteinemia-the-levodopa-connection/
Prospective study of methylenetetrahydrofolate reductase (MTHFR) variant C677T and risk of all-cause and cardiovascular disease...
OBJECTIVE: The objective was to examine associations of MTHFR C677T, a proxy for high homocysteine concentrations, with CVD ... A comparison of homozygotes at baseline showed that individuals with a TT genotype had a 2.2-μmol/L higher homocysteine and a ... a proxy for high homocysteine concentration) and death from CVD. ... a proxy for high homocysteine concentration) and death from CVD ... The association between blood homocysteine concentration and the risk of cardiovascular disease (CVD) remains controversial, ...https://www.ndph.ox.ac.uk/publications/329423
DrOlgaLazin: Homocysteine Causes, Symptoms, Treatment - What are the possible symptoms and signs of elevated homocysteine...
Oxidation of homocysteine to form derivative homocysteine species may result in the formation of homocysteine-mixed disulfides ... Homocysteine Topic Guide What are the possible symptoms and signs of elevated homocysteine levels? Elevated homocysteine levels ... Homocysteine Topic Guide What are the possible symptoms and signs of elevated homocysteine levels? Elevated homocysteine levels ... What are high homocysteine levels? What causes elevated homocysteine levels? Can elevated homocysteine levels be hereditary? ...http://olgaandrassy.blogspot.com/2017/01/homocysteine-causes-symptoms-treatment.html
MTHFR 677C--|T polymorphism and risk of coronary heart disease: a meta-analysis. - Oxford Clinical Trial Service Unit &...
DATA EXTRACTION: Data were collected on MTHFR 677C--,T genotype, case-control status, and plasma levels of homocysteine, folate ... These results support the hypothesis that impaired folate metabolism, resulting in high homocysteine levels, is causally ... T polymorphism is a genetic alteration in an enzyme involved in folate metabolism that causes elevated homocysteine ... individuals with elevated levels of plasma homocysteine tend to have moderately increased risk of coronary heart disease (CHD ...https://www.ctsu.ox.ac.uk/publications/49312
Plasma total homocysteine levels in postmenopausal women with unstable coronary artery disease
Plasma total homocysteine (tHey) is considered a risk factor for CAD, but the relationship between tHey and well-defined CAD in ... Plasma total homocysteine levels in postmenopausal women with unstable coronary artery disease. Nielsen, Niels Erik Linköping ... Homocysteine, Women, Unstable coronary artery disease, Coronary angiography, Odds ratio, Covariates, ROC curve National ... An elevated plasma total homocysteine (tHcy) level is considered a risk factor for coronary artery disease (CAD), but the ...http://liu.diva-portal.org/smash/record.jsf?pid=diva2:247599
... is a homocysteine (CHEBI:17230) L-homocysteine (CHEBI:17588) is a serine family amino acid (CHEBI: ... S-(5-deoxy-β-D-ribos-5-yl)-L-homocysteine (CHEBI:90364) has functional parent L-homocysteine (CHEBI:17588). L-homocysteine ... L-homocysteine (CHEBI:17588) is conjugate acid of L-homocysteinate (CHEBI:63072) L-homocysteine (CHEBI:17588) is tautomer of L- ... L-homocysteinate (CHEBI:63072) is conjugate base of L-homocysteine (CHEBI:17588). L-homocysteine zwitterion (CHEBI:58199) is ...http://www.ebi.ac.uk/chebi/searchId.do?chebiId=CHEBI:17588
... remethylation as determinant of enzyme inactivation and homocysteine export. J Pharmacol Exp Ther, v. 267, n. 3, p ... McCULLY, K. S. Homocysteine and vascular disease. Nat Med, n. 2, p. 386-9, 1996. [ Links ]. 46. McCULLY, K. S. Vascular ... Plasma homocysteine levels and mortality in patients with coronary artery disease. N Engl J Med, n. 337, p. 230-6, 1997. [ ... Plasma total homocysteine in health subjects: sex-specific relation with biological trials. Am J Clin Nutr, n. 64, p. 587-93, ...http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442004000500006&lang=pt
Elevated homocysteine levels have been observed in patients with MS. Studies have examined why plasma homocysteine levels are ... Homocysteine and vascular disease: review of published results of the homocysteine-lowering trials. J Inherit Metab Dis 2011; ... Homocysteine testing (measurement of plasma levels of homocysteine) may be considered medically necessary for the following ... Measurements of homocysteine (Hcy) levels are usually performed fasting. Normal homocysteine concentrations range between 5 and ...https://www.wellmark.com/Provider/MedpoliciesAndAuthorizations/MedicalPolicies/policies/Homocysteine_Testing.aspx
Homocysteine and Cholesterol | Lifescript.com
Homocysteine, an amino acid in the blood, is associated with an increased risk of heart attack and stroke. Some experts predict ... In addition, researchers haven't set a "safe" level of homocysteine.. The good news is that homocysteine levels can often be ... like your homocysteine level and C reactive protein.. Homocysteine, an amino acid in the blood, is associated with an increased ... Homocysteine and Cholesterol. Health Conditions. By Lisa Mosing, MS, RD, FADA, Special to LifeScript Published August 11, 2005 ...http://www.lifescript.com/health/centers/cholesterol/articles/homocysteine_and_cholesterol.aspx
Homocysteine and MTHFR Mutations | Circulation
Causes of Elevated Homocysteine Levels. Some people have elevated homocysteine levels (Table 1) caused by a deficiency of B ... How Is Homocysteine Measured?. Homocysteine is measured through a routine blood test. Most of the time, no preparations are ... Does Lowering Homocysteine Levels Decrease the Risk for Atherosclerosis and Thrombosis?. *How Can You Lower Homocysteine Levels ... Does Lowering Homocysteine Levels Decrease the Risk for Atherosclerosis and Thrombosis?. *How Can You Lower Homocysteine Levels ...http://circ.ahajournals.org/content/111/19/e289.long
Cross-references: Homocysteine-binding domain (IPR003726) | InterPro | EMBL-EBI
Cross-references: Homocysteine-binding domain (IPR003726). The following external resources were found for this entry:. ENZYME ...http://www.ebi.ac.uk/interpro/entry/IPR003726/xrefs