... homeodomain-interacting protein kinase) functions as a key regulator of multiple proteostatic stress responses, each ... Homeodomain-interacting protein kinase (HPK-1) kinase activity is necessary to improve proteostasis.. (A) Multiple sequence ... Neuronal homeodomain-interacting protein kinase (HPK-1) induces the proteostatic network in distal tissues.. (A) Fluorescent ... Homeodomain-interacting protein kinase (HPK-1) functions within the nervous system to regulate healthspan.. Video of wild-type ...
Reversible Dysfunction of Wild-Type p53 following Homeodomain-Interacting Protein Kinase-2 Knockdown Rosa Puca; Rosa Puca ... Homeodomain-interacting protein kinase-2 (HIPK2) is a positive regulator of p53 oncosuppressor function. Here, we show, by ... Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser46 and mediates apoptosis. Nat Cell Biol ... Homeodomain-interacting protein kinase-2 restrains cytosolic phospholipase A2-dependent prostaglandin E2 generation in human ...
ADAMTS Proteins ADAMTS1 Protein ADAMTS13 Protein ADAMTS4 Protein ADAMTS5 Protein ADAMTS7 Protein ADAMTS9 Protein Adansonia ... ... Antennapedia Homeodomain ProteinHomeodomain ProteinsTranscription FactorsNuclear ProteinsDrosophila ProteinsDNA-Binding ... Antennapedia homeodomain protein is a homeobox ... 2006; ANTENNAPEDIA HOMEODOMAIN PROTEIN was indexed under NUCLEAR PROTEINS & ... Proteins [D12.776] * DNA-Binding Proteins [D12.776.260] * Homeodomain Proteins [D12.776.260.400] * Antennapedia Homeodomain ...
Homeodomain Proteins - Fushi Tarazu Transcription Factors PubMed MeSh Term *Overview. Overview. subject area of * Requirement ...
Buy Homeodomain Only Protein (HOP) Polyclonal Antibody (Mouse), HRP at gentaur.com ... A Rabbit polyclonal antibody against Mouse Homeodomain Only Protein (HOP). This antibody is labeled with HRP. ... The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal ...
Buy Homeodomain Only Protein (HOP) Polyclonal Antibody (Human), APC-Cy7 at gentaur.com ... A Rabbit polyclonal antibody against Human Homeodomain Only Protein (HOP). This antibody is labeled with APC-Cy7. ... The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal ... C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and ...
Gehring WJ, Affolter M, Bürglin T (1994). "Homeodomain proteins". Annual Review of Biochemistry. 63: 487-526. doi:10.1146/ ... Cdx protein family DNA-binding protein Inhibitor of DNA-binding protein Mapper(2) Nuclear receptor, a class of ligand activated ... Homeo domain 3.1.1 Family: Homeo domain only; includes Ubx 3.1.2 Family: POU domain factors; includes Oct 3.1.3 Family: Homeo ... Bürglin TR, Affolter M (June 2016). "Homeodomain proteins: an update". Chromosoma. 125 (3): 497-521. doi:10.1007/s00412-015- ...
NKX3.1 homeodomain protein binds to topoisomerase I and enhances its activity. In: Cancer Research. 2007 ; Vol. 67, No. 2. pp. ... NKX3.1 homeodomain protein binds to topoisomerase I and enhances its activity. Cai Bowen, August Stuart, Jeong Ho Ju, Jenny ... NKX3.1 homeodomain protein binds to topoisomerase I and enhances its activity. / Bowen, Cai; Stuart, August; Ju, Jeong Ho et al ... NKX3.1 homeodomain protein binds to topoisomerase I and enhances its activity. Cancer Research. 2007 Jan 15;67(2):455-464. doi ...
Homeodomain Proteins / genetics * Homeodomain Proteins / metabolism * Humans * MAP Kinase Kinase Kinases / genetics ... mitogen-activated or extracellular signal-regulated protein kinase kinase), placing miR-221/222 downstream of the RAS pathway. ...
Homeodomain Proteins / genetics* * Homeodomain Proteins / ultrastructure * Nucleic Acid Conformation * Protein Biosynthesis / ... Keywords: ES9S; Hox cluster; RNA structure; RNA-protein interaction; expansion segment; internal initiation; internal ribosome ...
The 200-kDa CUX1 protein is highly expressed in the developing kidney, where it functions to regulate cell proliferation. ... We determined the pattern and timing of CUX1 protein expression in developing testes. CUX1 expression was continuous in Sertoli ... Transgenic mice ectopically expressing the 200-kDa CUX1 protein develop renal hyperplasia associated with reduced expression of ... The homeodomain CUX1 protein exists as multiple isoforms that arise from proteolytic processing of a 200-kDa protein or an ...
Expression of mOb1, a novel atypical 73 amino acid K50-homeodomain protein, during mouse development. / Adu, Jimi; Leong, F.T ... Expression of mOb1, a novel atypical 73 amino acid K50-homeodomain protein, during mouse development. Mechanisms of Development ... Expression of mOb1, a novel atypical 73 amino acid K50-homeodomain protein, during mouse development. In: Mechanisms of ... Dive into the research topics of Expression of mOb1, a novel atypical 73 amino acid K50-homeodomain protein, during mouse ...
Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins Share Share ... Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins ...
Nguyen, D. N. T., Rohrbaugh, M., & Lai, Z. C. (2000). The Drosophila homolog of Onecut homeodomain proteins is a neural- ... Nguyen, DNT, Rohrbaugh, M & Lai, ZC 2000, The Drosophila homolog of Onecut homeodomain proteins is a neural- specific ... The Drosophila homolog of Onecut homeodomain proteins is a neural- specific transcriptional activator with a potential role in ... Dive into the research topics of The Drosophila homolog of Onecut homeodomain proteins is a neural- specific transcriptional ...
The only conserved protein motif is a homeodomain closely related to the HB9/MNR2 homeodomain family (Fig. 1). Because there ... F, Comparison of percentage amino acid identity between HB9/MNR2 proteins in the homeodomain (HD, gray).d, Drosophila; m, mouse ... 1994) RK2, a glial-specific homeodomain protein required for embryonic nerve cord condensation and viability in Drosophila. ... 2002) Drosophila homeodomain protein dHb9 directs neuronal fate via crossrepressive and cell-nonautonomous mechanisms. Neuron ...
Duplicated homeodomain-like superfamily protein. Show species without binding site experiments. Motif. Genes. Species. atr. aly ...
homeodomain interacting protein kinase 2. ISO. CTD Direct Evidence: marker/mechanism. CTD. PMID:28318631. NCBI chr 4:67,439,327 ... Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine ... S100 calcium-binding protein A4. ISO. CTD Direct Evidence: marker/mechanism. CTD. PMID:30818366. NCBI chr 2:176,090,951... ... protein:increased expression:nephron tubule, kidney interstitium (human). RGD. PMID:10580398 PMID:21346373. RGD:12879397, RGD: ...
zinc finger homeodomain enhancer-binding protein. Background. ZEB1 encodes a zinc finger transcription factor that represses T- ... ZEB1 (NP_110378, 801 a.a. ~ 900 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ... Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control. ... CD63 is a type II membrane protein belonging to tetraspanin superfamily and it play key roles in the activation of several ...
The HNF1B gene provides instructions for making a protein called hepatocyte nuclear factor-1 beta (HNF-1β). Learn about this ... The HNF-1β protein is one of a large group of transcription factors called homeodomain proteins. The homeodomain is a region of ... Many change single protein building blocks (amino acids) in the HNF-1β protein. Others lead to an abnormally shaped protein or ... The HNF1B gene provides instructions for making a protein called hepatocyte nuclear factor-1 beta (HNF-1β). This protein ...
Figure 3: Distribution of genes encoding HD1 and HD2 homeodomain proteins in the matA locus and genes encoding pheromone ... It is composed of two genes encoding Y and Z homeodomain proteins of the HD2 and HD1 classes, respectively. The Y and Z ... Orthologs of S. commune proteins in the fungal kingdom.. Proteins of S. commune were assigned to orthologous groups with ... Protein families.. The PFAM database version 24.0 (ref. 39) was used to identify PFAM protein families. Custom scripts in ...
Family a.4.1.1: Homeodomain [46690] (41 proteins). Pfam PF00046. *. Protein Hypothetical protein 4930532d21rik [140157] (1 ... PDB Compounds: (A:) Hypothetical protein 4930532D21Rik. SCOPe Domain Sequences for d1x58a1:. Sequence; same for both SEQRES and ... Class a: All alpha proteins [46456] (290 folds). *. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies). core ... Superfamily a.4.1: Homeodomain-like [46689] (21 families) consists only of helices. ...
Wu, X.; Chen, H.; Parker, B.; Rubin, E.; Zhu, T.; Lee, J.S.; Argani, P.; Sukumar, S. HOXB7, a Homeodomain Protein, Is ... Fenton, H.; Carlile, B.; Montgomery, E.A.; Carraway, H.; Herman, J.; Sahin, F.; Su, G.H.; Argani, P. LKB1 protein expression in ... Wu, J.M.; Halushka, M.K.; Argani, P. Intratumoral heterogeneity of HER-2 gene amplification and protein overexpression in ... and Expression of Gross Cystic Disease Fluid Protein 15 (GCDFP) and Mammaglobin (MGB). American Journal of Clinical Pathology. ...
The E2A-PBX1 chimeric protein contains these transactivation domains fused to the homeodomain of PBX1. E2A-PBX1 binds DNA in a ... Each of the E2A proteins (E12 and E47) contains a bHLH domain that is responsible for sequence-specific DNA binding and protein ... The CDK4-cyclinD complex normally phosphorylates the retinoblastoma protein (Rb protein), leading to release of the E2F ... The p19ARF protein, which is encoded by the same locus as p16, also leads to cell cycle arrest by inhibiting the ability of ...
SATB1 is a homeodomain MAR binding protein. It recognizes ATC sequences that consist of stretches of As, Ts, and Cs on one ... SATB1 is a homeodomain MAR binding protein. It recognizes ATC sequences that consist of stretches of As, Ts, and Cs on one ... The 14/SATB1 monoclonal antibody specifically binds to the special AT-rich sequence binding protein 1 that is encoded by the ,/ ... The 14/SATB1 monoclonal antibody specifically binds to the special AT-rich sequence binding protein 1 that is encoded by the ,/ ...
SATB1 is a homeodomain MAR binding protein. It recognizes ATC sequences that consist of stretches of As, Ts, and Cs on one ... SATB1 is a homeodomain MAR binding protein. It recognizes ATC sequences that consist of stretches of As, Ts, and Cs on one ... The 14/SATB1 monoclonal antibody specifically binds to the special AT-rich sequence binding protein 1 that is encoded by the ,/ ... The 14/SATB1 monoclonal antibody specifically binds to the special AT-rich sequence binding protein 1 that is encoded by the ,/ ...
Combinatorial function of the homeodomain proteins Nkx2.1 and Gsh2 in ventral telencephalic patterning. Development. 130:4895- ... bone morphogenetic proteins (BMPs), Wingless/INT proteins (WNTs), transforming growth factors (TGFs) and retinoic acid (RA). ... zinc-finger proteins. also have essential functions. The main HD containing TF families are: paired-box (e.g. Pax6), forkhead ... WNT proteins and their downstream molecules have been found to be highly expressed right after the generation of NE cells. In ...
Conserved Protein Domain Family LIM_bind, The LIM-domain binding protein, binds to the LIM domain pfam00412 of LIM homeodomain ... LIM-domain binding protein. The LIM-domain binding protein, binds to the LIM domain pfam00412 of LIM homeodomain proteins which ... The Drosophila protein Chip is required for segmentation and activity of a remote wing margin enhancer. Chip is a ubiquitous ... that these proteins act synergistically to enhance transcriptional efficiency by acting as co-factors for LIM homeodomain and ...
maltose binding-a1 homeodomain protein chimera, crystal form I. 1mh4. maltose binding-a1 homeodomain protein chimera, crystal ... HOMEODOMAIN FROM THE DROSOPHILA PAIRED PROTEIN BOUND TO A DNA OLIGONUCLEOTIDE. 1ftt. THYROID TRANSCRIPTION FACTOR 1 HOMEODOMAIN ... Solution structure of the homeodomain-only protein HOP. 2hoa. STRUCTURE DETERMINATION OF THE ANTP(C39->S) HOMEODOMAIN FROM ... Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA. 1qry. Homeobox protein VND (ventral nervous system defective ...
HOX proteins execute their activity by exploiting a cooperative binding to PBX proteins and DNA. Therefore, an increase or ... Finally, the latter peptides in complex with PBX1 protein and DNA were exploited to run MD simulations and the ΔGbinding ... simulations in complex with PBX1 protein and DNA to evaluate complex binding stability. MM-GBSA calculations of the resulting ... HOX proteins have been extensively studied due to their pivotal role in transcriptional events. ...
Here the authors demonstrate that members of the Homeodomain-interacting protein kinases (HIPKs) HIPK3 and DYRK1A are also ... Homeodomain-interacting protein kinases (HIPKs) belong to the CMGC kinase family and are closely related to dual-specificity ... Homeodomain-interacting protein kinases, a novel family of co-repressors for homeodomain transcription factors. J. Biol. Chem. ... Novel homeodomain-interacting protein kinase family member, HIPK4, phosphorylates human p53 at serine 9. FEBS Lett. 581, 5649- ...