*  Gentium Receives Negative Opinion From the CHMP on Defibrotide for the Treatment and Prevention of VOD
... recommending the refusal of the marketing authorization for Defibrotide to treat and prevent hepatic veno-occlusive disease in ... recommending the refusal of the marketing authorization for Defibrotide to treat and prevent hepatic veno-occlusive disease (" ... Veno-occlusive disease (VOD) is a potentially life-threatening condition, which typically occurs as a significant complication ... Certain high-dose conditioning regimens used as part of stem cell transplantation can damage the lining cells of hepatic blood ...
  https://www.cnbc.com/id/100581799
*  Veno-Occlusive Disease - Hepatic and Biliary Disorders - Merck Manuals Professional Edition
... particularly when veno-occlusive disease is severe. In 25%, veno-occlusive disease is severe, accompanied by fulminant liver ... Hepatic veno-occlusive disease is caused by endothelial injury, leading to nonthrombotic occlusion of the terminal hepatic ... Veno-Occlusive Disease (Sinusoidal Obstruction Syndrome). By Nicholas T. Orfanidis, MD, Clinical Assistant Professor, Thomas ... 10 mm Hg suggests veno-occlusive disease). Measuring the pressure across the liver entails inserting a catheter percutaneously ...
  http://www.merckmanuals.com/professional/hepatic-and-biliary-disorders/vascular-disorders-of-the-liver/veno-occlusive-disease
*  Ignore Regeneron Pharmaceuticals, Inc: Here Are 3 Better Buys Right Now -- The Motley Fool
Defitelio was submitted as a potential treatment for severe hepatic veno-occlusive disease in adults and children undergoing ... Between its best-selling eye disease medication Eylea winning a handful of label expansions, and its new PCSK9 inhibitor ...
  https://www.fool.com/investing/general/2016/02/02/ignore-regeneron-pharmaceuticals-inc-here-are-3-be.aspx
*  Home - Sanofi Mobile Framework
Patients who have previously received a hematopoietic stem cell transplant (HSCT) are at higher risk for veno-occlusive disease ... Monitor hepatic function and for signs and symptoms of hepatitis and hepatic failure. Discontinue Clolar for Grade 3 or greater ... Severe and fatal hepatotoxicity, including hepatitis and hepatic failure, has occurred with the use of Clolar. In clinical ... There are no trials verifying an improvement in disease-related symptoms or increased survival with Clolar. ...
  http://clolar.com
*  Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study - Tabular View - ClinicalTrials.gov
Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study (Treatment IND). The safety and scientific ... Hepatic Veno-Occlusive Disease. Intervention ICMJE *Drug: Defibrotide Defibrotide is a single-stranded polydeoxyribonucleotide ... Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study. ... Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study. ...
  https://clinicaltrials.gov/ct2/show/record/NCT00628498?term=NCT00628498&rank=1
*  Busulfan (Intravenous Route) Description and Brand Names - Mayo Clinic
This medicine may cause hepatic veno-occlusive disease (HVOD). This usually occurs if you receive too much busulfan, or receive ... However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.. ...
  https://www.mayoclinic.org/drugs-supplements/busulfan-intravenous-route/description/DRG-20067303?p=1
*  Hepatic Veno-Occlusive Disease - Disease, Hepatic Veno-Occlusive Summary Report | CureHunter
Extracellular matrix, rich in FIBRONECTINS, is usually deposited around the HEPATIC VEINS leading to venous outflow occlusion ... Liver disease that is caused by injuries to the ENDOTHELIAL CELLS of the vessels and subendothelial EDEMA, but not by ... Hepatic Veno-Occlusive Disease (Disease, Hepatic Veno-Occlusive). Subscribe to New Research on Hepatic Veno-Occlusive Disease ... Disease, Hepatic Veno-Occlusive; Hepatic Veno Occlusive Disease; Hepatic Veno-Occlusive Diseases; Syndrome, Sinusoidal ...
  http://www.curehunter.com/public/keywordSummaryD006504-Hepatic-Veno-Occlusive-Disease-Disease--Hepatic-Veno-Occlusive.do
*  Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study - Full Text View - ClinicalTrials.gov
Hepatic Veno-Occlusive Disease. Liver Diseases. Digestive System Diseases. Vascular Diseases. Cardiovascular Diseases. ... Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study (Treatment IND). The safety and scientific ... Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study. ... Multi-institutional use of defibrotide in 88 patients after stem cell transplantation with severe veno-occlusive disease and ...
  https://clinicaltrials.gov/ct2/show/NCT00628498?state1=NA%3AUS%3ATX&state2=NA%3AUS%3ATX&locn=cook+children
*  Hepatic veno-occlusive disease - Wikipedia
Hepatic veno-occlusive disease or veno-occlusive disease (VOD) is a condition in which some of the small veins in the liver are ... Hepatic veno occlusive disease". www.orpha.net. Retrieved 2016-12-26. Dalle, JH; Giralt, SA (March 2016). "Hepatic Veno- ... Fulgenzi, A; Ferrero, ME (2016). "Defibrotide in the treatment of hepatic veno-occlusive disease". Hepatic medicine : evidence ... Toxic agents causing veno-occlusive disease include plants as well as the medication cyclophosphamide. Hepatic doppler ...
  https://en.wikipedia.org/wiki/Hepatic_veno-occlusive_disease
*  An Outbreak of Hepatic Veno-Occlusive Disease in Western Afghanistan Associated with Exposure to Wheat Flour Contaminated with...
An Outbreak of Hepatic Veno-Occlusive Disease in Western Afghanistan Associated with Exposure to Wheat Flour Contaminated with ... Faizullah Kakar, Zarif Akbarian, Toby Leslie, et al., "An Outbreak of Hepatic Veno-Occlusive Disease in Western Afghanistan ...
  https://www.hindawi.com/journals/jt/2010/313280/cta/
*  Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease...
Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease ... Study Comparing Efficacy and Safety of Defibrotide vs Best Supportive Care in the Prevention of Hepatic Veno-Occlusive Disease ... and be at high risk or very high risk of developing veno-occlusive disease (VOD). ... Patient has a serious active disease or co-morbid medical condition, as judged by the investigator, which would interfere with ...
  https://www.centerwatch.com/clinical-trials/listings/98260/veno-occlusive-disease-study-comparing-efficacy-safety/?section=elg
*  FDA Approves Defibrotide for Patients who Develop Hepatic Veno-Occlusive Disease After Transplant - ASH Clinical News
FDA Approves Defibrotide for Patients who Develop Hepatic Veno-Occlusive Disease After Transplant - Latest & Greatest, News - ... FDA Approves Defibrotide for Patients who Develop Hepatic Veno-Occlusive Disease After Transplant. Wednesday, June 1, 2016. ... The U.S. FDA approved defibrotide sodium for adults and children with hepatic veno-occlusive disease (VOD) with additional ... This is the first FDA-approved treatment for severe hepatic VOD. Hepatic VOD is a condition in which some of the veins in the ...
  https://www.ashclinicalnews.org/news/fda-approves-defibrotide-patients-develop-hepatic-veno-occlusive-disease-transplant/
*  Global Veno-Occlusive Hepatic Disease Therapeutics Market (Hospitals, Research Institutes. Ambulatory Surgical Centres and...
... analyzes and researches the Veno-Occlusive Hepatic Disease Therapeu ... This report studies the Global Veno-Occlusive Hepatic Disease Therapeutics Market 2017, ... 6.1 EU Veno-Occlusive Hepatic Disease Therapeutics Market Size (2012-2017). 6.2 EU Veno-Occlusive Hepatic Disease Therapeutics ... 7 Japan Veno-Occlusive Hepatic Disease Therapeutics Development Status and Outlook. 7.1 Japan Veno-Occlusive Hepatic Disease ...
  https://www.medgadget.com/2017/03/global-veno-occlusive-hepatic-disease-therapeutics-market-hospitals-research-institutes-ambulatory-surgical-centres-and-othersize-status-and-forecast-2022-global-qyresearch.html
*  Late-onset hepatic veno-occlusive disease after allografting: report of two cases with atypical clinical features successfully...
Late-onset hepatic veno-occlusive disease after allografting: report of two cases with atypical clinical features successfully ... veno-occlusive disease). Seminars in Liver Disease, 22, 27.. Shulman, H.M., Gown, A.M. & Nugent, D.J. (1987) Hepatic veno- ... Late-onset hepatic veno-occlusive disease after allografting: report of two cases with atypical clinical features successfully ... Hepatic Veno-occlusive disease (VOD) is a potentially severe complication of hematopoietic stem cell transplantation (HSCT). ...
  http://www.mjhid.org/index.php/mjhid/article/view/2018.001
*  Late-onset hepatic veno-occlusive disease after allografting: report of two cases with atypical clinical features successfully...
Late-onset hepatic veno-occlusive disease after allografting: report of two cases with atypical clinical features successfully ... Late-Onset Hepatic Veno-Occlusive Disease after Allografting: Report of Two Cases with Atypical Clinical Features Successfully ... The syndrome of hepatic veno-occlusive disease after marrow transplantation. Blood 1995; 85:3005-20. PMid:7756636 ... Hepatic Veno-Occlusive Disease (VOD) is a potentially severe complication of hematopoietic stem cell transplantation (HSCT). ...
  http://www.mjhid.org/index.php/mjhid/article/view/2018.001/html
*  DailyMed - BUSULFEX- busulfan injection
5.3 Hepatic Veno-Occlusive Disease (HVOD) 5.4 Embryo-fetal Toxicity 5.5 Cardiac Tamponade 5.6 Bronchopulmonary Dysplasia 5.7 ... Hepatic Veno-Occlusive Disease (HVOD): Increased risk of developing HVOD at AUC greater than 1,500 µM•min. Monitor serum ... 5.3 Hepatic Veno-Occlusive Disease (HVOD) Current literature suggests that high busulfan area under the plasma concentration ... VOD = Veno-Occlusive Disease of the liver ‡ GVHD = Graft versus Host Disease ...
  https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e03a2579-fb59-4c77-b487-0a72cb8cd76e
*  May 10, 2016 - The ASCO Post
Defibrotide Sodium for Hepatic Veno-occlusive Disease After HSCT. In the Clinic provides overviews of novel oncology agents, ...
  http://www.ascopost.com/issues/may-10-2016/
*  GastroHep News Story
Doppler-ultrasonography predicts severity of hepatic veno-occlusive disease. Doppler-ultrasonography can predict the severity ... The researchers investigated a noninvasive method capable of predicting the severity of veno-occlusive disease (VOD) at the ... of veno-occlusive disease after stem cell transplantation, claims a team from Villejuif, France.. ...
  http://www.gastrohep.com/news/news.asp?id=1450
*  SP110 Gene - GeneCards | SP110 Protein | SP110 Antibody
hepatic venoocclusive disease with immunodeficiency. *hepatic veno-occlusive disease with immunodeficiency. *20301448 ... Diseases associated with SP110 include Hepatic Venoocclusive Disease With Immunodeficiency and Mycobacterium Tuberculosis, ... Hepatic venoocclusive disease with immunodeficiency (VODI) [MIM:235550]: Autosomal recessive primary immunodeficiency ... 5) MalaCards diseases for SP110 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, DISEASES, and GeneCards. ...
  http://www.genecards.org/cgi-bin/carddisp.pl?gene=SP110
*  Gemcitabine - FDA prescribing information, side effects and uses
Hepatic veno-occlusive disease has been reported.. Pulmonary - Parenchymal toxicity, including interstitial pneumonitis, ... b Partial response non-measurable disease. c Independent reviewers could not evaluate disease demonstrated by sonography or ... Hepatic Toxicity [see Warnings and Precautions (5.5)]. *Embryo-fetal Toxicity [see Warnings and Precautions (5.6), Use in ... Median time to disease progression for the Gemcitabine plus cisplatin arm was 5.0 months compared to 4.1 months on the ...
  https://www.drugs.com/pro/gemcitabine.html
*  Pertussis - Health Articles
Pulmonary veno-occlusive disease - The Diagnosis *Pulmonary veno-occlusive disease - The Risk factors ... Treatment of the complications of cirrhosis - Hepatic encephalopathy *Treatment of the complications of cirrhosis - Variceal ... Restrictive lung diseases (Respiratory Disease) - The Preventions *Restrictive lung diseases (Respiratory Disease) - Treatments ... Coronary heart disease Treatments In conventional medicine perspective *Coronary heart disease Treatments In Herbal medicine ...
  http://kylenorton.healthblogs.org/category/pertussis/
*  Histopathology - Volume 34, Issue 1 - January 1999 - Wiley Online Library
Hepatic stellate cells (Ito cells) in veno-occlusive disease of the liver after allogeneic bone marrow transplantation (pages ...
  http://onlinelibrary.wiley.com/doi/10.1111/his.1999.34.issue-1/issuetoc
*  Browse Cochrane - Essential Evidence Plus
Hepatic veno-occlusive disease (VOD) is a severe complication after haematopoietic stem cell transplantation (HSCT). Different ... Interventions for prophylaxis of hepatic veno-occlusive disease in people undergoing haematopoietic stem cell transplantation ... Communication problems in health care may arise as a result of healthcare providers focusing on diseases and their management, ... Familial Mediterranean fever, a hereditary auto-inflammatory disease, mainly affects ethnic groups living in the Mediterranean ...
  http://www.essentialevidenceplus.com/content/cochrane?page=177&results=20&class=none