*  Immobilized cytochrome c bound to cardiolipin exhibits peculiar oxidation state-dependent axial heme ligation and catalytically...
Axial coordination of the ferric heme thus differs from the (LS) 6c His/Lys and (LS) 6c His/OH- states observed in solution. ... Surface-enhanced resonance Raman (SERR) studies allowed the axial heme iron ligands to be identified, which were found to be ... Immobilized cytochrome c bound to cardiolipin exhibits peculiar oxidation state-dependent axial heme ligation and catalytically ... Immobilized cytochrome c bound to cardiolipin exhibits peculiar oxidation state-dependent axial heme ligation and catalytically ...
  https://iris.unimore.it/handle/11380/1065990
*  Subcellular Localization of Iron and Heme Metabolism Related Proteins at Early Stages of Erythrophagocytosis - pdf descargar
Subcellular Localization of Iron and Heme Metabolism Related Proteins at Early Stages of Erythrophagocytosis. . Biblioteca ... heme is rapidly degraded through the catabolic activity of heme oxygenase HO. Extracted heme iron is then either exported or ... thereby suggesting a model for heme catabolism occurring outside the phagosome, with heme likely being transported into the ... However, the cellular localization of the early steps of heme processing and iron extraction during EP remains to be clearly ...
  http://libros.duhnnae.com/2017/jun7/149816174770-Subcellular-Localization-of-Iron-and-Heme-Metabolism-Related-Proteins-at-Early-Stages-of-Erythrophagocytosis.php
*  Cytochrome c-type heme lyase
These data indicate that heme contacts mediated by residues within these domains modulate the dynamics of heme binding and ... Links covalently the heme group to the apoprotein of cytochrome c. The protein encoded by this gene is an enzyme that ... cysteines and histidine of the heme attachment site, Cys-XX-Cys-His play a key role in mitochondrial holocytochrome c synthase ... Mechanisms of mitochondrial holocytochrome c synthase and the key roles played by cysteines and histidine of the heme ...
  https://pharos.nih.gov/idg/targets/P53701
*  The interaction of covalently bound heme with the cytochrome c maturation protein CcmE. - Radcliffe Department of Medicine
In addition, the properties of the heme resonances of the holo-protein as compared with those of a form of CcmE with non- ... covalently bound heme provide evidence for the modification of one of the heme vinyl side chains by the protein, most likely ... In the continued absence of a structure of the holoform of CcmE, identification of the heme ligands is an important step in ... In this work, we present spectroscopic data that provide insight into the ligation of the heme iron in the soluble domain of ...
  https://www.rdm.ox.ac.uk/publications/100803
*  Eukaryotic Heme Utilization - Caroline Philpott
Very little is known about heme transport in eukaryotes and a heme-specific transport uptake systems have not been identified ... Heme transporters from C. elegans have heme uptake activity when expressed in yeast and mutant forms of heme transporters ... We analyzed its heme transport activity in yeast and found evidence that the protein encoded by LHR1 was also a heme importer ... Heme is synthesized in mitochondria, yet the cofactor is used in compartments throughout the cell. Heme is highly hydrophobic ...
  http://grantome.com/grant/NIH/ZIA-DK054513-07
*  Structural Biochemistry/Protein function/Heme group - Wikibooks, open books for an open world
Heme proteins have some iron-porphyrins such as heme a, heme b, heme c, heme d, heme d1, heme o, etc. They are constituted by ... Heme C[edit]. Heme C differs from heme B in that the two vinyl side from the heme B are substituted with a covalently thioether ... Heme A[edit]. Heme A is a bimolecular heme that is made up of of macrocyclic ligand called a porphyrin, chelating an iron atom ... Heme D[edit]. Heme D is another form of heme B. Instead, the hydroxylated propionic acid side chain forms a gamma-spirolactone ...
  https://en.wikibooks.org/wiki/Structural_Biochemistry/Protein_function/Heme_group
*  Heme iron intake, dietary antioxidant capacity, and risk of colorectal adenomas in a large cohort study of French women |...
Heme iron intake, dietary antioxidant capacity, and risk of colorectal adenomas in a large cohort study of French women. Nadia ... Heme iron intake, dietary antioxidant capacity, and risk of colorectal adenomas in a large cohort study of French women ... Results:Heme iron intake was positively associated with colorectal and colon adenoma risks (HR for the fourth vs. first ... Heme iron intake, dietary antioxidant capacity, and risk of colorectal adenomas in a large cohort study of French women ...
  http://cebp.aacrjournals.org/content/early/2016/01/28/1055-9965.EPI-15-0724
*  FA Biochemistry Heme Synthesis Flashcards - Cram.com
Study Flashcards On FA Biochemistry Heme Synthesis at Cram.com. Quickly memorize the terms, phrases and much more. Cram.com ... ":"FA Biochemistry Heme Synthesis","payreferer_url":"\/flashcards\/copy\/fa-biochemistry-heme-synthesis-360466","isGuest":true ...
  http://www.cram.com/flashcards/fa-biochemistry-heme-synthesis-360466
*  Heme Oxygenase Attenuates Angiotensin II-Mediated Increase in Cyclooxygenase-2 Activity in Human Femoral Endothelial Cells |...
COX-1 and COX-2 are heme proteins,6 and it is well documented that the heme prosthetic group of both COX isoforms is essential ... Heme oxygenase (HO) regulates cellular heme levels and catalyzes the formation of bilirubin and carbon monoxide. We hypothesize ... Regulation of cyclooxygenase by the heme-heme oxygenase system in microvessel endothelial cells. J Pharmacol Exp Ther. 2002; ... it is also magnified in cells treated with exogenous heme to compensate for reductions in cellular heme levels owing to HO-1 ...
  http://hyper.ahajournals.org/content/41/3/715
*  HEME OXYGENASE (PS00593) | InterPro | EMBL-EBI
HEME_OXYGENASE (PS00593). Accession PS00593 Integration. Haem oxygenase conserved site (IPR018207) Member database. PROSITE ...
  http://www.ebi.ac.uk/interpro/ISignatureOverview?sig=PS00593&query=P
*  Heme Peroxidases (RSC Publishing)
Heme Peroxidases serves as an essential text for those working in industry and academia in biochemistry and metallobiology. ... Chapters written and edited by worldwide experts span a range of heme peroxidases from plants, yeast, bacteria and mammals. ... This book provides a comprehensive single source of information on the various aspects of heme peroxidase structure, function ... Heme peroxidases are widely distributed in biological systems and are involved in a wide range of processes essential for life ...
  http://pubs.rsc.org/en/content/ebook/978-1-84973-911-5
*  Heme | Technology Trends
Biocrystallization - Heme. ... avoid destruction by this molecule, the parasite biocrystallizes heme to form hemozoin ... Heme ... Heme. A heme (American English) or haem (British English) is a prosthetic group that consists of an iron ion contained in the ... Heme - Genes. ... The following genes are part of the chemical pathway for making heme ALAD aminolevulinic acid, delta-, ... bonding prefers a bent geometry for the heme-NO complex ... Thus nitric oxide binding ferrous heme at the distal position gives ...
  http://www.primidi.com/heme
*  Heme facts, information, pictures | Encyclopedia.com articles about Heme
Make research projects and school reports about Heme easy with credible articles from our FREE, online encyclopedia and ... Hemoglobin consists of a complex of a protein plus heme. Heme consists of iron plus protoporphyrin IX. Normally, during the ... haem (heme) A metal-chelate complex in which iron is bonded to the four nitrogens of a porphyrin ring structure. The word (and ... haem (heme) An iron-containing molecule (see formula) that binds with proteins as a cofactor or prosthetic group to form the ...
  http://encyclopedia.com/science-and-technology/biochemistry/biochemistry/heme
*  Heme Motions | JILA Science
What is this thing called heme? And, how does it do such amazing work inside our bodies? Scientists know that heme is a large ... In the heme molecule shown at right, the iron atom is green and the atoms in the porphyrin ring are carbon (teal), nitrogen ( ... Our lives depend on heme. As part of hemoglobin, it carries oxygen to our tissues. As part of cytochrome c, it helps transform ... Understanding how heme functions at the biomolecular level is a hot research topic for biophysicists, including Research ...
  https://jila.colorado.edu/node/5196
*  Endogenous Estrogen-Mediated Heme Oxygenase Regulation in Experimental Menopause
... Anikó Pósa,1 Renáta Szabó,1 Anett Csonka,1 ... A. M. K. Choi, "Heme oxygenase-1 protects the heart," Circulation Research, vol. 89, no. 2, pp. 105-107, 2001. View at Google ... T. M. Chen, J. Li, L. Liu et al., "Effects of heme oxygenase-1 upregulation on blood pressure and cardiac function in an animal ... Y. M. Lee, P. Y. Cheng, S. F. Hong et al., "Oxidative stress induces vascular heme oxygenase-1 expression in ovariectomized ...
  https://www.hindawi.com/journals/omcl/2015/429713/ref/
*  Heme oxygenase-1: a metabolic nike. | Sigma-Aldrich
The heme oxygenases (HO) are metabolic enzymes that utilize NADPH and oxygen to break apart the heme moiety liberating ... Heme oxygenase-1: a metabolic nike.. [Barbara Wegiel, Zsuzsanna Nemeth, Matheus Correa-Costa, Andrew C Bulmer, Leo E Otterbein] ... Heme that is derived from hemoproteins can be toxic to the cells and if not removed immediately, it causes cell apoptosis and ... Further, heme is an important component of a number of metabolic enzymes, and, therefore, HO-1 plays an important role in the ...
  https://www.sigmaaldrich.com/catalog/papers/24180257
*  Recombinant Human Heme Oxygenase 1 protein (ab86919)
Buy our Recombinant Human Heme Oxygenase 1 protein. Ab86919 is a protein fragment produced in Escherichia coli and has been ... Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to ... Recombinant Human Heme Oxygenase 1 protein. See all Heme Oxygenase 1 proteins and peptides. ... Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are ...
  http://www.abcam.com/recombinant-human-heme-oxygenase-1-protein-ab86919.html
*  Heme-Egr-1 | Circulation Research
Unbound heme, is a strong oxidant, and its hydrophobic nature permits rapid entry into cells of the vascular wall. Once heme ... The importance of heme metabolism has been highlighted in clinical observations in which the lack of capacity to degrade heme ... oxidized heme) exposure and how they may contribute to the confounding actions of heme. Their findings are significant because ... HO-1 levels may be insufficient to break down increased levels of heme. Heme is an important inducer of HO-1 expression, and ...
  http://circres.ahajournals.org/content/102/1/6
*  Biology of Heme in Mammalian Erythroid Cells and Related Disorders
This review will focus on the biology of heme in mammalian erythroid cells, including the heme biosynthetic pathway as well as ... Biology of Heme in Mammalian Erythroid Cells and Related Disorders. Tohru Fujiwara1,2 and Hideo Harigae1,2 ... Heme is a prosthetic group comprising ferrous iron (Fe2+) and protoporphyrin IX and is an essential cofactor in various ... Heme biosynthesis is induced during erythroid differentiation and is coordinated with the expression of genes involved in ...
  https://www.hindawi.com/journals/bmri/2015/278536/abs/
*  Myoglobin Human heme free | ProSpec
The Myoglobin heme free contains N-terminal T7 tag and purified by proprietary chromatographic techniques. ... Recombinant Human Myoglobin heme free produced in E.Coli is a non-glycosylated polypeptide chain having a molecular mass of ... Myoglobin heme free although stable at 15°C for 2 weeks, should be stored at 4°C. For long term storage it is recommended to ... Myoglobin heme free Human Recombinant produced in E.Coli is a non-glycosylated polypeptide chain having a molecular mass of ...
  https://www.prospecbio.com/Myoglobin_Human_heme_free
*  RCSB PDB - Protein Feature View - Heme oxygenase 1 - P06762 (HMOX1 RAT)
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to ... Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are ... Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis. UniProt ...
  http://www.rcsb.org/pdb/protein/P06762
*  Heme Oxygenase-1 Detection: ELISAs and Antibodies
Heme Oxygenase-1 Detection. Heme oxygenase-1 (HO-1) is a microsomal enzyme that degrades heme, a prosthetic group of the heme ... Heme oxygenase exists in at least two isozyme forms: heme oxygenase-1 and heme oxygenase-2, each of which differs in tissue ... Antibodies for Heme Oxygenase-1 Detection. Anti-Heme Oxygenase-1 Antibody, Monoclonal (Clone GTS-1) and Anti-Heme Oxygenase-1 ... Heme oxygenase‑1. M174. IHC. WB. Heme oxygenase‑1 inhibition assay. Rat. (GTS-1). Mouse IgG1 MoAb. Cross-reacts with human and ...
  http://www.clontech.com/US/Products/Cell_Biology_and_Epigenetics/Cell_Proliferation_and_Viability/Heme_Oxygenase-1?sitex=10020:22372:US&PEBCL1=zjSgfwItVwkgPgXTDIiLgJk7fa&PEBCL1_pses=ZGDA5926A0884E3B659A91BD6C03C75314F0DD912290C026E1776337865235E3BD84DE34A7C7A118006B622F01CF6C93ED3F262CD98CCD9AFD
*  The Alternative Route to Heme in the Methanogenic Archaeon Methanosarcina barkeri
... a heme synthase that converts Fe-COPRO III into heme during the alternative heme biosynthesis pathway in Methanosarcina barkeri ... The presence of heme in the purified AhbAB complex was completely unexpected. Usually, heme serves as a redox cofactor in ... The ratio of heme to AhbAB was estimated by peak integration after HPLC analysis and was determined to be about 0.03 mol heme ... b) Heme biosynthesis gene clusters in M. barkeri. Genes encoding enzymes which catalyze the early steps during heme formation ...
  https://www.hindawi.com/journals/archaea/2014/327637/
*  Sexual Dimorphism of Cardiovascular Ischemia Susceptibility Is Mediated by Heme Oxygenase
X. N. Nguyen and P. A. Dennery, "Nuclear translocation of heme oxygenase-1 and heme oxygenase-2 proteins: a novel signaling ... HO is the rate-limiting enzyme in heme catabolism; it catalyzes the breakdown of heme into equimolar amounts of carbon monoxide ... Figure 3: Heme-oxygenase expression (HO2 and HO-1 expressed as %) in the aortic of male (the black square) and female (the grey ... Figure 2: Heme-oxygenase expression (HO-2 and HO-1 expressed as %) in the cardiac left ventricle of male (the black square) and ...
  https://www.hindawi.com/journals/omcl/2013/521563/