Regulation of Antibody Response in Vitro | The Journal of Immunology
... in vitro anti-hapten antibody response of the primed cells was studied. It was found that stimulation of Rag-sensitized cells ... studied enhanced antibody response when they were added to primed lymph node cells which had been treated with a hapten-protein ...http://www.jimmunol.org/content/112/5/1685
Genetic regulation of the antibody response to H-2Db alloantigens in mice. II. Tolerance to non-H-2 determinants abolishes the...
A hypothesis was proposed comparing the H-2Db antigen on a congenic cell to a hapten on a nonimmunogenic carrier which fails to ...http://jem.rupress.org/content/144/1/266
IMMUNOLOGICAL TOLERANCE IN BONE MARROW-DERIVED LYMPHOCYTES | JEM
The present studies were designed to probe the role(s) of T cells in preventing or altering tolerance induction in hapten- ... This was accomplished by using hapten conjugates of normally immunogenic heterologous carriers to selectively inhibit 2,4- ...http://jem.rupress.org/content/139/6/1464
DELETION OF HAPTEN-BINDING CELLS BY A HIGHLY RADIOACTIVE 125I CONJUGATE | JEM
The deletion was hapten specific and independent of the radioactive carrier to which the hapten was bound. DNP-binding cells ... DELETION OF HAPTEN-BINDING CELLS BY A HIGHLY RADIOACTIVE 125I CONJUGATE. Dov Theo Golan, Yves Borel ... DELETION OF HAPTEN-BINDING CELLS BY A HIGHLY RADIOACTIVE 125I CONJUGATE ... protein carrier conjugates specifically inactivated cells able to mount an immune response to that hapten after in vivo ...http://jem.rupress.org/content/136/2/305
All 6-letter words containing Letters A, H, N, P and T
HAPTEN & HATPIN. Every word on this site can be used while playing scrabble. Create other lists, that start with or end with ... hapten n. (immunology) Any small molecule that can elicit an immune response only when attached to a large carrier. ...https://www.bestwordlist.com/c/a/5/6letterwordswithahnpt.htm
"Antibody response of athymic nude mice to hapten coupled to thymus-dep" by T Kuhara, M Fujiwara et al.
Antibody response of athymic nude mice to hapten coupled to thymus-dependent carrier: the effect of hapten density. ... Kuhara, T; Fujiwara, M; and Jr, A K., "Antibody response of athymic nude mice to hapten coupled to thymus-dependent carrier: ... the effect of hapten density." (1978). Subject Strain Bibliography 1978. 2113. https://mouseion.jax.org/ssbb1978/2113 ...https://mouseion.jax.org/ssbb1978/2113/
Antibodies for Detecting Membrane-Surface Labels-Note 13.2 | Thermo Fisher Scientific
Fluorescent conjugates of several of these anti-dye and anti-hapten antibodies are also available. These antibodies can be used ... Fluorescent conjugates of several of these anti-dye and anti-hapten antibodies are available; see Anti-Dye and Anti-Hapten ...https://www.thermofisher.com/us/en/home/references/molecular-probes-the-handbook/technical-notes-and-product-highlights/antibodies-for-detecting-membrane-surface-labels.html
NAVER Academic | Perspectives on the regulatory biology of the B lymphocyte
Methods have been developed for the clonal stimulation of these cellsin vitro, with a single, hapten-specific B cell as the ... B lymphocytes with receptors specific for a particular hapten have been prepared through an antigen-affinity procedure. ... Methods have been developed for the clonal stimulation of these cellsin vitro, with a single, hapten-specific B cell as the ... B lymphocytes with receptors specific for a particular hapten have been prepared through an antigen-affinity procedure. ...http://academic.naver.com/article.naver?doc_id=34669635
"Antibody responses to trinitrophenyl (tnp)-l-glutamic acid60- -l-alani" by N L. Letvin, K L. Rock et al.
Antibody responses to trinitrophenyl (tnp)-l-glutamic acid60- -l-alanine30-l-tyrosine10 (gat) in microcultures: anti-hapten and ... anti-hapten and anti-carrier responses appear to be under separable control." (1982). Subject Strain Bibliography 1982. 3398. ...https://mouseion.jax.org/ssbb1982/3398/
Carrier Independent T Cell Helper Effects in Antigenic Stimulation | The Journal of Immunology
Thus, specific T cells contribute significantly, not only to stimulation by the hapten on the homologous carrier, but also when ... These results are interpreted as indicating a role for collaborative interactions of hapten-specific T cells with B cells ... mice before their transfer to irradiated non-immune recipients decreased the ability of such cells to be stimulated by hapten ... hapten is presented on heterologous and even poorly immunogenic carriers. ...http://www.jimmunol.org/content/111/4/1140
Hapten - Wikipedia
Hapten inhibition or "semi-hapten" is the inhibition of a type III hypersensitivity response. In inhibition, free hapten ... The concept of haptens emerged from the work of Karl Landsteiner who also pioneered the use of synthetic haptens to study ... Sometimes the small-molecule hapten can even block immune response to the hapten-carrier adduct by preventing the adduct from ... Once the body has generated antibodies to a hapten-carrier adduct, the small-molecule hapten may also be able to bind to the ...https://en.wikipedia.org/wiki/Hapten
Hapten - Sandwich Labeling of Cell-Surface Antigens | SpringerLink
Hapten Group Biotin Hydrazide Avidin Molecule Conventional Sandwich Trinitrobenzene Sulfonate These keywords were added by ... Hapten-sandwich labeling uses instead detector-coupled antihapten antibodies to amplify first-layer antibodies to which the ... The last few years have seen the introduction of hapten-sandwich labeling procedures (Lamm et al,1972; Wofsy et al.,1974; ... Wofsy L., Henry C., Cammisuli S. (1978) Hapten - Sandwich Labeling of Cell-Surface Antigens. In: Reisfeld R.A., Inman F.P. (eds ...https://link.springer.com/chapter/10.1007/978-1-4757-0779-3_7
hapten - definition and meaning
hapten: A small molecule that reacts with a specific antibody but cannot induce the formation of antibodies unless bound to a ... Janda attaches a hapten - which is either a bit of the drug itself, or a synthetic version of it - to a larger protein that ... Carrier proteins such as DT stimulate T-helper cells which co-operate with B-cells to enable them to respond to the hapten by ... First of all, the method does not work with just any antibodies, it works with antibodies to a particular hapten (a β-diketone ...https://www.wordnik.com/words/hapten
Thermodynamic model of binding of flexible bivalent haptens to antibody (Journal Article) | ETDEWEB
... fragment to a hapten-Fab' complex) is strongly dependent on the length of the hapten. We present a simple model for predicting ... fragment to a hapten-Fab' complex) is strongly dependent on the length of the hapten. We present a simple model for predicting ... In particular we used the model to obtain the dependence of the cross-linking constant on the length of th hapten, the depth to ... In particular we used the model to obtain the dependence of the cross-linking constant on the length of th hapten, the depth to ...https://www.osti.gov/etdeweb/biblio/6138048
Conjugated hapten | definition of conjugated hapten by Medical dictionary
What is conjugated hapten? Meaning of conjugated hapten medical term. What does conjugated hapten mean? ... Looking for online definition of conjugated hapten in the Medical Dictionary? conjugated hapten explanation free. ... conjugated hapten. con·ju·gat·ed hap·'ten. a hapten that may cause the production of antibodies when it has been covalently ... con·ju·gat·ed hap·ten. (kon'jŭ-gā-tĕd hap'ten) A hapten that may cause the production of antibodies when it has been covalently ...https://medical-dictionary.thefreedictionary.com/conjugated+hapten
Definition for hapten
hapten definition: a tiny molecule that reacts with a certain antibody but cannot induce the formation of antibodies unless ... Definition for "hapten"*a tiny molecule that reacts with a certain… ... How would you define hapten?. All the definitions on AZdictionary were written by people just like you. Now's your chance to ... Medical Dictionary for "hapten"*In immunology, a molecule that's unable,… ...https://www.azdictionary.com/definition/hapten
Anti-Hapten Chicken Antibodies of the 7S Class | The Journal of Immunology
Anti-Hapten Chicken Antibodies of the 7S Class Message Subject (Your Name) has forwarded a page to you from The Journal of ... Anti-Hapten Chicken Antibodies of the 7S Class. Edward W. Voss Jr. and Herman N. Eisen ...http://www.jimmunol.org/content/109/5/944
Simple radiometric method for accurately quantitating epitope densities of hapten-protein conjugates with sulfhydryl linkages |...
Here we report a simple radiometric method that uses 14C-labeled cystine to measure hapten epitope densities during sulfhydryl ... especially with the use of small haptens, large molecular weight carrier proteins, and limited amounts of protein. ... Control of small molecule hapten epitope densities on antigenic carrier proteins is essential for development and testing of ... conjugation of haptens to maleimide activated carrier proteins. ... Control of small molecule hapten epitope densities on antigenic ...https://www.rti.org/publication/simple-radiometric-method-accurately-quantitating-epitope-densities-hapten%E2%80%93protein
DIGITAL.CSIC: Site-heterologous haptens and competitive monoclonal antibody-based immunoassays for pyrimethanil residue...
Site-heterologous haptens and competitive monoclonal antibody-based immunoassays for pyrimethanil residue analysis in ...https://digital.csic.es/handle/10261/127803
NIOSHTIC-2 Publications Search - 20028901 - Hapten and antibody production for a sensitive immunoassay determining a human...
The immunizing haptens, except for hapten 5, provided the target specific antibodies. Molecular modeling of the haptens ... Six ELISAs with both a heterologous hapten structure and a heterologous hapten configuration (cis/trans or trans/cis) between ... hapten 3), N-(cis/trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane-1-carbonyl)-4-amino-l-phenylalanine (hapten 5), N-(N-( ... or trans-hapten-thyroglobulin conjugate as immunogens were screened against numerous hapten-bovine serum albumin conjugates as ...https://www.cdc.gov/niosh/nioshtic-2/20028901.html
Direct Evidence for the Formation of Diastereoisomeric Benzylpenicilloyl Haptens from Benzylpenicillin and Benzylpenicillenic...
The Diastereoisomeric Penicillin Hapten Formation Depends on PA.. To determine how BP forms diastereoisomeric haptens in the ... Characterization of Penicillin Hapten Formed by BP and PA In Vitro.. Mass spectrometric analysis revealed that both BP and PA ... Penicillin Hapten Formed in Patients.. HSA was extracted by affinity chromatography from a pool of plasma samples donated by ... To probe the mechanism of penicillin hapten formation in vitro and in vivo, the aminolysis reactions of BP or PA with N-acetyl ...http://jpet.aspetjournals.org/content/338/3/841
RCSB PDB - 1KEL: CATALYTIC ANTIBODY 28B4 FAB FRAGMENT COMPLEXED WITH HAPTEN (1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO]...
CATALYTIC ANTIBODY 28B4 FAB FRAGMENT COMPLEXED WITH HAPTEN (1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO] METHYLPHOSPHONIC ACID) ... The x-ray crystal structures of the sulfide oxidase antibody 28B4 and of antibody 28B4 complexed with hapten have been solved ... The x-ray crystal structures of the sulfide oxidase antibody 28B4 and of antibody 28B4 complexed with hapten have been solved ... CATALYTIC ANTIBODY 28B4 FAB FRAGMENT COMPLEXED WITH HAPTEN (1-[N-4'-NITROBENZYL-N-4'-CARBOXYBUTYLAMINO] METHYLPHOSPHONIC ACID) ...https://www.rcsb.org/structure/1KEL
Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to...
Attachment at the universal position works with different haptens, antibodies, and payloads. Examples are the haptens Fluo, Dig ... Humanized hapten-binding IgGs were designed with an accessible cysteine close to their binding pockets, for specific covalent ... Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to ... in proximity to binding pockets but without contributing to hapten interactions. Payloads that carry a free thiol are ...https://www.sigmaaldrich.com/catalog/papers/25670234
Hapten | Article about hapten by The Free Dictionary
Find out information about hapten. An incomplete antigen that cannot induce antibody formation by itself but can do so by ... coupling with a larger carrier molecule Explanation of hapten ... Hapten Antibody Anti-Hapten Method. *hapten inhibition of ... hapten. Also found in: Dictionary, Medical, Wikipedia.. Related to hapten: complete antigen, Tolerogen hapten. (immunology) An ... Also, Hapten Sciences is reviewing other applications related to this approach for other dermatology conditions.. Hapten ...http://encyclopedia2.thefreedictionary.com/hapten