Dienekes' Anthropology Blog: Finally, structure in haplogroup R1a (Underhill et al. 2009)
My own R1a1 67-matker haplotype is VERY close to a bunch of Indian R1a1 haplotypes, and we share the same branch on a 67-marker ... The thing is that the Russian R1a1 haplotypes are practically identical with the Indian 'Indo-European' R1a1 haplotypes. The ... All these folks rose in area where the dominant haplotype is J2. This is incorrect!. The Hittites were an Indo-European ... Why Y-STR haplotype clusters are not clades. Racial Type of the Ancient Hellenes. Anthropological Evidence and the Fallmerayer ...http://dienekes.blogspot.com/2009/11/finally-structure-in-haplogroup-r1a.html?showComment=1257383263586
Dienekes' Anthropology Blog: Major study of Iberian Y-chromosomes (Adams et al.)
Why Y-STR haplotype clusters are not clades. Racial Type of the Ancient Hellenes. Anthropological Evidence and the Fallmerayer ... You can, if you wish, make the hard work of comparing haplotypes (they are listed in the supplemental material) but that's a ... Admixture analysis based on binary and Y-STR haplotypes indicates a high mean proportion of ancestry from North African (10.6 ... Within R1b3, R1b3* appears closely interconnected by haplotype on first sight. R1b3f appears as the most common subclade, ...http://dienekes.blogspot.com/2008/12/major-study-of-iberian-y-chromosomes.html?showComment=1229073000000
Genome-wide SNP analysis reveals no gain in power for association studies of common variants in the Finnish Saami
Haplotype diversity was reduced and, on average, levels of LD were higher in the Saami as compared with those in the HapMap ... Nevertheless, the reduced haplotype diversity could potentially facilitate gene identification, especially if multiple rare ...http://liu.diva-portal.org/smash/record.jsf?pid=diva2:666273
Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment.
We employed SNP, haplotype, and multiple-gene analysis to evaluate associations. PDK1 interacted with dietary fat for both ... Haplotypes*. Humans. Insulin Resistance / genetics. Minnesota. PTEN Phosphohydrolase / genetics, metabolism. ... Statistically significant interaction with dietary carbohydrates and rectal cancer was detected by haplotype analysis of PDK1. ... with diet and illustrate the importance of evaluating dietary interactions beyond the level of single SNPs or haplotypes when a ...http://www.biomedsearch.com/nih/Diet-Colorectal-Cancer-Analysis-Candidate/21999454.html
Dienekes' Anthropology Blog: Y chromosomes of Teleuts
Phylogenetic analysis of N3a haplotypes suggested specificity of Teleut haplotypes and their closeness to those of Tomsk Tatars ... distinguished for highly specific profile of YSTR haplotypes and high haplotype diversity. The results of the comparative ... Teleut haplotypes are those of Hazaras from Pakistan,' which suggests that these Teleut individuals actually should belong to ... It was demonstrated that Teleuts and Southern Altaians had very close and overlapping profiles of R1a1 haplotypes. Population ...http://dienekes.blogspot.com/2009/09/y-chromosomes-of-teleuts.html?showComment=1254509119243
Comparative SNP and Haplotype Analysis Reveals a Higher Genetic Diversity and Rapider LD Decay in Tropical than Temperate...
The big window size haplotypes (3-SNP slide-window covering 2160 kb on average) revealed much higher genetic diversity than the ... The polymorphic information content values revealed by the haplotypes (0.436-0.566) were generally much higher than individual ... markers of high quality and compared for genetic diversity and LD decay using the SNPs and their haplotypes developed from ...http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0024861
Analysis of the IBD5 locus and potential gene-gene interactions in Crohn's disease | Gut
Variants from the IBD5 haplotype were extremely rare in the Japanese.. Conclusions: The IBD5 risk haplotype is associated with ... Terwilliger JD, Ott J. A haplotype-based 'haplotype relative risk' approach to detecting allelic associations. Hum Hered1992;42 ... IBD5 haplotype status did not have a significant effect on age at diagnosis in log rank comparisons between groups (data not ... The IBD5 haplotype and the Arg702Trp/Leu1007fsinsC CARD15 variants were associated with CD (table 4), as observed in the TDT ...http://gut.bmj.com/content/52/4/541
Dienekes' Anthropology Blog: Y chromosome haplogroups of ancient Southern Siberians from Krasnoyarsk
Why Y-STR haplotype clusters are not clades. Racial Type of the Ancient Hellenes. Anthropological Evidence and the Fallmerayer ...http://dienekes.blogspot.com/2008/03/y-chromosome-haplogroups-of-ancient.html?showComment=1206171960000
Haplotype Structure and Genotype-Phenotype Correlations of the Sulfonylurea Receptor and the Islet ATP-Sensitive Potassium...
Common haplotypes (frequency ,3%) are shown in the top panel, and together they compose 92% of all haplotypes in this region; ... OR = 1.17 for E23K). Haplotype E carries the K allele of E23K, but it is the only haplotype that carries the minor allele at ... Haplotype structure.. To evaluate the haplotype structure of the SUR1/Kir6.2 gene region, we genotyped 129 publicly available ... Haplotype structure across the SUR1/Kir6.2 gene region.. To characterize haplotype structure across the SUR1/Kir6.2 gene region ...http://diabetes.diabetesjournals.org/content/53/5/1360.full
Welcome to CDC stacks | A genetic association study detects haplotypes associated with obstructive heart defects - 30276 | CDC...
Haplotypes Heart Defects, Congenital Humans Logistic Models Polymorphism, Single Nucleotide Pregnancy Tumor Suppressor Proteins ... We conducted a haplotype-based genetic association study of obstructive heart defects (OHDs), aiming to detect the genetic ... Four haplotype blocks, located in genes MGMT, MTHFS, CBS, and DNMT3L, were statistically significant using a Bayesian false- ... By examining the association between 140 haplotype blocks, we identified 9 blocks that are potentially associated with OHD ...https://stacks.cdc.gov/view/cdc/30276
Haplotype structure and selection of the MDM2 oncogene in humans - CSHL Scientific Digital Repository
In this report, the haplotype structure of the MDM2 gene is determined by using 14 different SNPs across the gene from three ... This observation, coupled with the relatively high frequency of the G allele haplotype in both and Caucasian and Ashkenazi ... African Continental Ancestry Group Alleles Entropy European Continental Ancestry Group Gene Frequency Genotype Haplotypes ... Haplotype structure and selection of the MDM2 oncogene in humans. Proc Natl Acad Sci U S A, 104 (11). pp. 4524-9. ISSN 0027- ...http://repository.cshl.edu/22964/
The association of INOS promoter haplotypes with rheumatoid arthritis - Nuffield Department of Orthopaedics, Rheumatology and...
The association of INOS promoter haplotypes with rheumatoid arthritis Share Share Share Share ...https://www.ndorms.ox.ac.uk/publications/157047
"Delayed-type hypersensitivity to h-y in "nonresponder" mouse haplotype" by leigh J. Barrington
Barrington, leigh J., "Delayed-type hypersensitivity to h-y in 'nonresponder' mouse haplotypes." (1982). Subject Strain ...https://mouseion.jax.org/ssbb1982/187/
Palmer Collaborative MS Research Center Award: MS Targeted Haplotype Project - National Multiple Sclerosis Society
Haplotype mapping involves identifying and mapping on chromosomes blocks of genes, called haplotypes, which are inherited ... Palmer Collaborative MS Research Center Award: MS Targeted Haplotype Project. $825,000; 4/1/03-3/31/08. Funded in full by a ... Lander, is turning his focus on multiple sclerosis as a test case for using a new approach called haplotype mapping to find ... His team is beginning a major, government-supported $20-million effort to map haplotypes across the entire human genome, and ...https://secure.nationalmssociety.org/site/SPageServer/?pagename=HOM_RES_research_haflerteam
Infection frequency of hepatitis C virus and IL28B haplotypes in Papua New Guinea, Fiji, and Kiribati. - Oxford Neuroscience
All antibody-positive participants bar one had HCV protective haplotypes. Our results suggest that HCV is present in these ... Infection frequency of hepatitis C virus and IL28B haplotypes in Papua New Guinea, Fiji, and Kiribati. ... All antibody-positive participants bar one had HCV protective haplotypes. Our results suggest that HCV is present in these ... Infection frequency of hepatitis C virus and IL28B haplotypes in Papua New Guinea, Fiji, and Kiribati. ...https://www.neuroscience.ox.ac.uk/publications/420852
Haplotype-based approach to known MS-associated regions increases the amount of explained risk - Semantic Scholar
SNP-haplotypes (of various lengths from 1 up to 15 contiguous SNPs) were constructed at each of the 110 previously identified, ... Here we compare the use of multi-SNP-haplotypes to the use of single-SNPs as alternative methods to describe MS genetic risk. ... Also, the use of SNP-haplotypes can lead to the discovery of new regions of interest, which have not been identified by a ... By contrast, in no region was the single-SNP based model similarly more significant than the SNP-haplotype based model. ...https://www.semanticscholar.org/paper/Haplotype-based-approach-to-known-MS-associated-re-Khankhanian-Gourraud/2a6f6508e10fee2bae5ac13566c384825ebbd949
The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases -...
The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases ... 1999) The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological ... An individual's major histocompatibility complex (MHC) ancestral haplotype (AH) is the dearest single determinant of ...http://researchrepository.murdoch.edu.au/id/eprint/15013/
Genotypes and haplotypes in the insulin-like growth factors, their receptors and binding proteins in relation to plasma...
In the haplotype analysis we found that the AC haplotype was associated with higher levels of IGFBP3 than the AG haplotype and ... None of the common haplotypes within the IGF1 receptor (IGF1R) haplotype or IGFALS haplotype were found significantly ... One haplotype in IGF2 was associated with the levels of both IGF1 and IGFBP3, while two haplotypes in the IGF2R gene were ... Two haplotype variants and two SNPs in IGF2R were associated with the levels of IGF1. Both variants of the IGFBP3 haplotype and ...https://bmcmedgenomics.biomedcentral.com/articles/10.1186/1755-8794-3-9
HLA-DRB and HLA-DQB Allele and Haplotype Frequencies in Iranian Patients with Recurrent Aphthous Stomatitis
In order to evaluate the association of HLA-DR and DQ alleles and haplotypes, 54 patients with RAS and 100 unrelated healthy ... RAS appears to be associated with some human leukocyte antigen (HLA) class II alleles and haplotypes. This study attempts to ... However, DRB*07:01/DQB1*03:02 haplotype was found to be significantly frequent in patients than controls. In respect of HLA ... The DRB*04/DQB1*03:01 and DRB*01:01/DQB1*02:01 haplotypes were significantly distributed in healthy subjects compared with ...http://rrc.tums.ac.ir/publication/view/id/436?lang=en
"Efficient mining of haplotype patterns for linkage disequilibrium mapp" by Lin L., Wong L. et al.
Linkage disequilibrium mapping is the process of finding disease gene locations through comparisons of haplotype frequencies ... and Haplotype Pattern Mining (HPM). Experimental results show that for a substantial class of problems, our method has good ... LinkageTracker does not require any population ancestry information about the disease and the genealogy of the haplotypes. ... Lin L., Wong L., Tze-Yun LEONG, and Lai P.. Efficient mining of haplotype patterns for linkage disequilibrium mapping. (2010). ...http://ink.library.smu.edu.sg/sis_research/3016/
Population Genetic Analysis of Haplotypes Based on 17 Short Tandem Repeat Loci on Y Chromosome in Population Sample from...
Results A total of 207 haplotypes were recorded, 197 of which were unique (90%). Haplotype diversity was 0.9993, with the most ... Y-chromosome SNP haplotypes suggest evidence of gene flow among caste, tribe, and the migrant Siddi populations of Andhra ... The haplotype frequencies were determined by direct counting and analyzed using Arlequin 3.1 and analysis of molecular variance ... Aim To analyze the haplotype of the Ezhava population of Kerala, south India, using 8 short tandem repeat (STR) loci on the Y ...http://pdc-connection.ebscohost.com/c/articles/52291709/population-genetic-analysis-haplotypes-based-17-short-tandem-repeat-loci-y-chromosome-population-sample-from-eastern-croatia
Gene polymorphisms of novel immunotolerant molecule BTLA: distribution of alleles, genotypes and haplotypes in Polish Caucasian...
gene polymorphism B lymphocyte T lymphocyte interleukin T helper cell allele distribution genotype haplotype Polish Caucasian ... Gene polymorphisms of novel immunotolerant molecule BTLA: distribution of alleles, genotypes and haplotypes in Polish Caucasian ...http://agro.icm.edu.pl/agro/element/bwmeta1.element.agro-0638aecc-d17c-4b32-be09-98f8aa1e2418
Analysis of Plasmodium vivax Apical Membrane Antigen-1 (PvAMA-1) Haplotypes among Iranian Isolates - International Journal of...
The scattering plot haplotypes by age showed an increasing incidence rate with age during childhood whereas incidence was the ... Keywords: Apical membrane antigen-1 (AMA-1), DNA sequencing, genetic polymorphism, Haplotype, Malaria transmission, Plasmodium ... Analysis of Plasmodium vivax Apical Membrane Antigen-1 (PvAMA-1) Haplotypes among Iranian Isolates ... Haplotypes among Iranian Isolates. Int J Mol Cell Med. 2017; 6 (4) URL: http://ijmcmed.org/article-1-735-en.html ...http://ijmcmed.org/browse.php?a_id=735&sid=1&slc_lang=en&ftxt=0
HLA DR-DQ haplotypes and genotypes in patients with systemic lupus erythematosus with co-existing Sjogren's syndrome, systemic...
... had revealed an increased frequency of the DRB1*0301-DQA1*0501-DQB1*0201 haplotype, as well as of the extended haplotype DRB1* ... HLA DR-DQ haplotypes and genotypes in patients with systemic lupus erythematosus with co-existing Sjogren's syndrome, systemic ... In contrast, SLE-noSS patients had an increased estimated frequency of the DRB1*1501-DQA1*0102-DQB1*0602 haplotype. In SLE-SS ... In the present study, we conducted a thorough evaluation of the genotype and haplotype profiles in well-defined subgroups of ...https://arthritis-research.biomedcentral.com/articles/10.1186/ar1621